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Journal Articles

Single-Cell Profiling of Signal Transduction Pathways in Pediatric T-Cell Acute Lymphoblastic Leukemia By Mass Cytometry:Dissecting JAK/STAT and PI3K/Akt/mTOR Active Signalling

Daniela Kužílková, PhD, Tomas Kalina, MD PhD, Cristina Bugarin, Dr., Katerina Rejlová, Dr., Daniel Thurner, Dr., Pavel Semerák, Dr., Jan Stuchly, MSc, Andrea Biondi, MD PhD, Giuseppe Gaipa, PhD

Blood (2020) 136 (Supplement 1): 38–39.

https://doi.org/10.1182/blood-2020-141973

Published: 2020

Journal Articles

Donor-Derived CAR T Cells Engineered with Sleeping Beauty Achieve Anti-Leukemic Activity without Severe Toxicity

Blood (2020) 136 (Supplement 1): 34.

https://doi.org/10.1182/blood-2020-141236

Published: 2020

Journal Articles

Transient Switch to Myeloid Lineage in Acute Lymphoblastic Leukemia during Induction Therapy: The Role of CD371 Expression and Implication for Minimal Residual Disease Detection

Elena Varotto, MD PhD, Margarita Maurer-Granofszky, PhD, Daniela Silvestri, Pamela Scarparo, PhD, Ester Mejstrikova, MD PhD, Monika Brüggemann, Giovanni Cazzaniga, PhD, Valentino Conter, MD, Ondrej Hrusak, MD PhD, Giuseppe Gaipa, PhD, Angela Schumich, Maria Grazia Valsecchi, PhD, Giuseppe Basso, MD PhD, Michael Dworzak, MD, Barbara Buldini, MD PhD

Blood (2019) 134 (Supplement_1): 377.

https://doi.org/10.1182/blood-2019-127287

Published: 2019

Journal Articles

Donor-Derived CD19 CAR Cytokine Induced Killer (CIK) Cells Engineered with Sleeping Beauty Transposon for Relapsed B-Cell Acute Lymphoblastic Leukemia (B-ALL)

Blood (2019) 134 (Supplement_1): 200.

https://doi.org/10.1182/blood-2019-125894

Published: 2019

Journal Articles

Glucocorticoids-Resistant Leukemic B-Cells Undergo a Phenotypic Change That Increases Sensitivity to SRC/ABL Inhibition

Jolanda Sarno, PhD, Christina Bligaard Pedersen, MSc, Astraea Jager, BS, Tyler Burns, PhD, Giuseppe Gaipa, PhD, Garry P. Nolan, PhD, Alessio Felice Bava, PhD, Kara L. Davis, DO

Blood (2018) 132 (Supplement 1): 1546.

https://doi.org/10.1182/blood-2018-99-117443

Published: 2018

Journal Articles

Flow Cytometric Measurement of the Initial In Vivo Response to Prednisone Provides New Prognostic Information in Childhood Acute Lymphoblastic Leukemia (ALL)

Giuseppe Gaipa, PhD, Oscar Maglia, Simona Sala, Bsc, Noemi Marino, Daniela Silvestri, Maria Grazia Valsecchi, PhD, Andrea Biondi, MD, Valentino Conter, MD

Blood (2018) 132 (Supplement 1): 2827.

https://doi.org/10.1182/blood-2018-99-116782

Published: 2018

Journal Articles

Targeting a Specific Glycosylated Epitope of CD43 with a New Humanized Monoclonal Antibody for the Treatment of Pediatric and Adult T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Cirino Botta, MD, Giuseppe Gaipa, PhD, Maria Eugenia Gallo Cantafio, PhD, Chiara Buracchi, PhD, Maria Anna Siciliano, MD, Caterina Riillo, MD, Katia Grillone, PhD, Alessandro Gulino, Maria Cucè, Nicoletta Staropoli, Andrea Ghelli Luserna Di Rora, Franca Maria Tuccillo, Maria Teresa Di Martino, Claudio Tripodo, MD, Marco Rossi, MD, Giovanni Martinelli, Andrea Biondi, MD, Pierosandro Tagliaferri, Pierfrancesco Tassone, MD

Blood (2018) 132 (Supplement 1): 1418.

https://doi.org/10.1182/blood-2018-99-118572

Published: 2018

Journal Articles

Clinical-Grade Transduction of Allogeneic Cytokine Induced Killer (CIK) Cells with CD19 Chimeric Antigen Receptor (CAR) Using Sleeping Beauty (SB) Transposon: Successful GMP-Compliant Manufacturing for Clinical Applications

Blood (2018) 132 (Supplement 1): 196.

https://doi.org/10.1182/blood-2018-196

Published: 2018

Journal Articles

Final Analysis of a Multicenter Pilot Phase 2 Study of Cytokine Induced Killer (CIK) Cells for Patients with Relapse after Allogeneic Transplantation

Blood (2016) 128 (22): 1160.

https://doi.org/10.1182/blood.V128.22.1160.1160

Published: 2016

Journal Articles

Manufacturing of Mesenchymal Stromal Cells for the Treatment of Graft-Versus-Host Disease: A Survey within the European Society of Blood and Marrow Transplantation

Blood (2016) 128 (22): 3374.

https://doi.org/10.1182/blood.V128.22.3374.3374

Published: 2016

Journal Articles

Euroflow-Based Immunophenotypic Characterization of CD34+ Cell Compartment in Juvenile Myelomonocytic Leukemia (JMML): A New Tool for Differential Diagnosis

Giuseppe Gaipa, PhD, Cristina Bugarin, Sergio Matarraz, Chiara Buracchi, PhD, Lukasz Sedek, MDPhD, Vincent H.J. van der Velden, PhD, Tomasz Szczepanski, Prof MD PhD, Alita van der Sluijs, Elaine Sobral da Costa, Michaela Novakova, Ester Mejstrikova, MD PhD, Carmen Aanei, Jacques JM van Dongen, Andrea Biondi, MD, Alberto Orfao, MD PhD

Blood (2016) 128 (22): 3127.

https://doi.org/10.1182/blood.V128.22.3127.3127

Published: 2016

Journal Articles

A Multicenter Phase II Study of Sequential Administration of Unmanipulated DLI and Donor Derived Cytokine Induced Killer (CIK) Cells in HSCT Patients, Relapsed of Disease

Martino Introna, MD, Elisa Gotti, BA, Michela Bonzi, BA, Josee Golay, PhDBA, Alessandra Algarotti, MD, Caterina Micò, MD, Anna Grassi, MD, Cristina Boschini, Maria Luisa Ferrari, BSc, Irene Cavattoni, MD, Ettore Biagi, MD, Adriana Balduzzi, Sr., MD, Attilio Rovelli, MD, Paolo Perseghin, MD, Giuseppe Gaipa, PhD, Andrea Biondi, Alessandro Rambaldi, MD

Blood (2015) 126 (23): 3160.

https://doi.org/10.1182/blood.V126.23.3160.3160

Published: 2015

Journal Articles

Mass Cytometry Analysis Dissects CRLF2-Driven Signaling Pathways in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL)

Jolanda Sarno, Kara L. Davis, DO, Angela Maria Savino, PhD, Cristina Bugarin, Stefania Pinto, Chiara Buracchi, PhD, Astraea Jager, BS, Chiara Palmi, PhD, Ruth C Barber, PhD, Daniela Silvestri, Gianni Cazzaniga, PhD, Martin J.S. Dyer, Prof., Andrea Biondi, Prof, MD, Garry P. Nolan, Prof, PhD, Giuseppe Gaipa, PhD

Blood (2015) 126 (23): 906.

https://doi.org/10.1182/blood.V126.23.906.906

Published: 2015

Journal Articles

Increased Frequency of Cells with Activated Ribosomal Protein S6 at Diagnosis Associates with MRD Positivity and Relapse in Childhood BCP ALL

Kara L. Davis, DO, Jolanda Sarno, Andrea Biondi, Prof, MD, Astraea Jager, BS, Giuseppe Gaipa, PhD, Zinaida Good, Garry P. Nolan, Prof, PhD

Blood (2015) 126 (23): 2616.

https://doi.org/10.1182/blood.V126.23.2616.2616

Published: 2015

Journal Articles

Role of the Histone Deacetylase Inhibitor Givinostat (ITF2357) in Treatment of CRLF2 Rearranged Acute Lymphoblastic Leukemia

Angela Maria Savino, Jolanda Sarno, Luca Trentin, Margherita Vieri, Grazia Fazio, PhD, Michela Bardini, Cristina Bugarin, Gianluca Fossati, Kara L. Davis, DO, Giuseppe Gaipa, PhD, Lueder Hinrich Meyer, MD, Garry P. Nolan, Prof, PhD, Andrea Biondi, Prof, MD, Geertruy Te Kronnie, PhD, Chiara Palmi, PhD, Giovanni Cazzaniga

Blood (2015) 126 (23): 2534.

https://doi.org/10.1182/blood.V126.23.2534.2534

Published: 2015

Journal Articles

Fine Tuning of Surface CRLF2 Expression and Its Associated Signalling Profile in Childhood B Cell Precursor Acute Lymphoblastic Leukemia

Giuseppe Gaipa, PhD, Cristina Bugarin, Chiara Palmi, PhD, Jolanda Sarno, Angela Savino, Oscar Maglia, Geertruy te Kronnie, Giovanni Cazzaniga, Andrea Biondi, MD

Blood (2012) 120 (21): 1409.

https://doi.org/10.1182/blood.V120.21.1409.1409

Published: 2012

Journal Articles

Recurrent SETBP1 Mutations in Atypical Chronic Myeloid Leukemia Abrogate an Ubiquitination Site and Dysregulate SETBP1 Protein Levels

Blood (2012) 120 (21): LBA-2.

https://doi.org/10.1182/blood.V120.21.LBA-2.LBA-2

Published: 2012

Journal Articles

Understanding the Immunomodulatory Effect of Mesenchymal Stem Cell Infused In Transplanted Patients with Steroid-Refractory GvHD

Erica Dander, PhD, Giovanna Lucchini, MD, Paola Vinci, Martino Introna, MD, Sonia Bonanomi, MD, Adriana Balduzzi, MD, Giuseppe Gaipa, PhD, Paolo Perseghin, MD, Francesca Masciocchi, Chiara Capelli, PhD, Josée Golay, PhD, Alessandra Algarotti, MD, Alessandro Rambaldi, MD, Attilio Rovelli, MD, Andrea Biondi, MD, Ettore Biagi, MD, Giovanna D'Amico, PhD

Blood (2010) 116 (21): 2306.

https://doi.org/10.1182/blood.V116.21.2306.2306

Published: 2010

Journal Articles

Feasibility of Multicentric Assessment of MRD in All by Flow-Cytometry: Standardization and Experience of the I-BFM-ALL FCM-MRD Study Group.

Giuseppe Gaipa, PhD, Marinella Veltroni, PhD, Richard Ratei, MD, Wolf-Dieter Ludwig, MD, Andrea Biondi, MD, Giuseppe Basso, MD, Michael N. Dworzak, MD

Blood (2004) 104 (11): 1079.

https://doi.org/10.1182/blood.V104.11.1079.1079

Published: 2004

NARROW

Single-Cell Profiling of Signal Transduction Pathways in Pediatric T-Cell Acute Lymphoblastic Leukemia By Mass Cytometry:Dissecting JAK/STAT and PI3K/Akt/mTOR Active Signalling

Donor-Derived CAR T Cells Engineered with Sleeping Beauty Achieve Anti-Leukemic Activity without Severe Toxicity

Transient Switch to Myeloid Lineage in Acute Lymphoblastic Leukemia during Induction Therapy: The Role of CD371 Expression and Implication for Minimal Residual Disease Detection

Donor-Derived CD19 CAR Cytokine Induced Killer (CIK) Cells Engineered with Sleeping Beauty Transposon for Relapsed B-Cell Acute Lymphoblastic Leukemia (B-ALL)

Glucocorticoids-Resistant Leukemic B-Cells Undergo a Phenotypic Change That Increases Sensitivity to SRC/ABL Inhibition

Flow Cytometric Measurement of the Initial In Vivo Response to Prednisone Provides New Prognostic Information in Childhood Acute Lymphoblastic Leukemia (ALL)

Targeting a Specific Glycosylated Epitope of CD43 with a New Humanized Monoclonal Antibody for the Treatment of Pediatric and Adult T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Clinical-Grade Transduction of Allogeneic Cytokine Induced Killer (CIK) Cells with CD19 Chimeric Antigen Receptor (CAR) Using Sleeping Beauty (SB) Transposon: Successful GMP-Compliant Manufacturing for Clinical Applications

Final Analysis of a Multicenter Pilot Phase 2 Study of Cytokine Induced Killer (CIK) Cells for Patients with Relapse after Allogeneic Transplantation

Manufacturing of Mesenchymal Stromal Cells for the Treatment of Graft-Versus-Host Disease: A Survey within the European Society of Blood and Marrow Transplantation

Euroflow-Based Immunophenotypic Characterization of CD34+ Cell Compartment in Juvenile Myelomonocytic Leukemia (JMML): A New Tool for Differential Diagnosis

A Multicenter Phase II Study of Sequential Administration of Unmanipulated DLI and Donor Derived Cytokine Induced Killer (CIK) Cells in HSCT Patients, Relapsed of Disease

Mass Cytometry Analysis Dissects CRLF2-Driven Signaling Pathways in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL)

Increased Frequency of Cells with Activated Ribosomal Protein S6 at Diagnosis Associates with MRD Positivity and Relapse in Childhood BCP ALL

Role of the Histone Deacetylase Inhibitor Givinostat (ITF2357) in Treatment of CRLF2 Rearranged Acute Lymphoblastic Leukemia

Fine Tuning of Surface CRLF2 Expression and Its Associated Signalling Profile in Childhood B Cell Precursor Acute Lymphoblastic Leukemia

Recurrent SETBP1 Mutations in Atypical Chronic Myeloid Leukemia Abrogate an Ubiquitination Site and Dysregulate SETBP1 Protein Levels

Understanding the Immunomodulatory Effect of Mesenchymal Stem Cell Infused In Transplanted Patients with Steroid-Refractory GvHD

Feasibility of Multicentric Assessment of MRD in All by Flow-Cytometry: Standardization and Experience of the I-BFM-ALL FCM-MRD Study Group.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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