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Journal Articles

Cumulative Incidence of Blood Stream Infections during Acute Myeloid Leukemia Treatment in the Netherlands: A 15-Year Overview

Emily Risa Schwartz, Sc.B., A.B., Kim Klein, MD MSc, Valerie de Haas, MD PhD, Birgit Lissenberg-Witte, PhD, Lynn Ball, MD, Natasja Dors, MD, Marry M Van den Heuvel-Eibrink, Prof, MD PhD, Rutger Knops, MD, Wim Tissing, MD, Birgitta A. Versluys, MD PhD, Christian M. Zwaan, MD, Raphaele R.L. van Litsenburg, MD PhD, Gertjan J.L. Kaspers, MD PhD

Blood (2018) 132 (Supplement 1): 2685.

https://doi.org/10.1182/blood-2018-99-114364

Published: 2018

Journal Articles

Obesity Is Associated with Favorable Cytogenetic Abnormalities in Pediatric Acute Myeloid Leukemia

Ditte Juel Adolfsen Løhmann, MD, Jonas Abrahamsson, MD PhD, Shau-Yin Ha, MD PhD, Olafur G. Jonsson, MD PhD, Gertjan J.L. Kaspers, MD PhD, Minna M Koskenvuo, MD PhD, Birgitte Lausen, MD PhD, Barbara De Moerloose, MD PhD, Josefine Palle, MD PhD, Bernward Zeller, MD PhD, Henrik Hasle, MD PhD, Lillian Sung, MD PhD

Blood (2017) 130 (Supplement 1): 1302.

https://doi.org/10.1182/blood.V130.Suppl_1.1302.1302

Published: 2017

Journal Articles

A Dynamic Epigenetic Landscape in Genetic and Immunophenotypic Stable Pediatric AML

Diana Hanekamp, MSc, Jennifer R. Scheick, Yaseswini Neelamraju, Edwin Sonneveld, PhD, Valerie de Haas, MD PhD, Gert J. Ossenkoppele, MD PhD, Gerrit J. Schuurhuis, PhD, Gertjan J.L. Kaspers, MD PhD, Francine E. Garrett-Bakelman, MDPhD, Jacqueline Cloos, PhD

Blood (2017) 130 (Supplement 1): 2686.

https://doi.org/10.1182/blood.V130.Suppl_1.2686.2686

Published: 2017

Journal Articles

Differences in Infection Prophylaxis between Pediatric AML Study Groups within the International BFM Study Group

Kim Klein, MD MSc, Henrik Hasle, MD PhD, Jonas Abrahamsson, MD PhD, Barbara De Moerloose, MD PhD, Gertjan J.L. Kaspers, MD PhD

Blood (2017) 130 (Supplement 1): 2104.

https://doi.org/10.1182/blood.V130.Suppl_1.2104.2104

Published: 2017

Journal Articles

Targeted Deep Sequencing of GATA1 more Sensitively Identifies Transient Myeloproliferative Disorder in Neonates with Down Syndrome

Bianca F Goemans, MD PhD, Sanne Noort, MD MSc, Marjolein Blink, MD PhD, Ko van Wouwe, MD PhD, Gertjan J.L. Kaspers, MD PhD, Valerie de Haas, MD PhD, Wouter J.W. Kollen, MD PhD, Vincent van der Velden, PhD, Tanja A. Gruber, MD PhD, Michel Zwaan, MD PhD

Blood (2017) 130 (Supplement 1): 2919.

https://doi.org/10.1182/blood.V130.Suppl_1.2919.2919

Published: 2017

Journal Articles

Characteristics and Outcomes of Pediatric Patients with t(16;16)-AML: Results of a Case Series By the International BFM Study Group

Kim Klein, MD MSc, Valerie de Haas, MD PhD, Jonas Abrahamsson, MD PhD, Todd A Alonzo, PhD, Brenda Gibson, MD PhD, Christine J Harrison, PhD FRCPath, Henrik Hasle, MD PhD, Betsy A Hirsch, PhD, Guy Leverger, MD PhD, Franco Locatelli, MD PhD, Susana C. Raimondi, PhD, Jeffrey E Rubnitz, MD PhD, Dirk Reinhardt, MD PhD, Daisuke Tomizawa, MD PhD, Gertjan J.L. Kaspers, MD PhD

Blood (2017) 130 (Supplement 1): 2671.

https://doi.org/10.1182/blood.V130.Suppl_1.2671.2671

Published: 2017

Journal Articles

The Prognostic Impact of Cytogenetics and Karyotype Changes in Pediatric Patients with Relapsed Acute Myeloid Leukemia: A Retrospective Cohort Study within the Relapsed AML 2001/01 Study

Blood (2016) 128 (22): 2896.

https://doi.org/10.1182/blood.V128.22.2896.2896

Published: 2016

Journal Articles

Excellent Outcome in Pediatric AML with Response Guided Chemotherapy without Allogeneic HSCT in First Complete Remission: Results from Protocol DB-AML01

Eveline de Bont, MD PhD, Ardine Reedijk, MSc, Tim Lammens, PhD, Valerie de Haas, MD PhD, Barbara Denys, PhD, Laurence Dedeken, MD, Marry van den Heuvel, MD PhD, Maroeska Loo, MD PhD, Anne Uyttebroeck, An Vandamme, MD PhD, Jutte VanderWerff-ten Bosch, MD PhD, Jozsef Zsiros, Gertjan J.L. Kaspers, MD PhD, Barbara Moerloose, MD PhD

Blood (2015) 126 (23): 2506.

https://doi.org/10.1182/blood.V126.23.2506.2506

Published: 2015

Journal Articles

Risk-Group Stratified and Minimal Residual Disease (MRD)-Guided Treatment with Extended ATRA and Reduced-Anthracycline Chemotherapy in Childhood Acute Promyelocytic Leukemia (APL): Results from ICC APL Study 01 (NCT01226303; EudraCT 2008-002311-40)

Anna Maria Testi, MD, Andrea Pession, MD, David Grimwade, PhD FRCPath, Daniela Diverio, PhD, Christine Ragu, PhD, Sarah Elitzur, MD, Alcira Fynn, MD, Henrik Hasle, MD PhD, Jutte Van der Werff ten Bosch, MD PhD, Owen Smith, MD, Brenda Gibson, MD, Franco Locatelli, MD PhD, Gertjan J.L. Kaspers, MD PhD

Blood (2015) 126 (23): 563.

https://doi.org/10.1182/blood.V126.23.563.563

Published: 2015

Journal Articles

Marcks Marks Resistance to Proteasome Inhibitors: Exocytosis of Polyubiquitinated Proteins in Bortezomib-Resistant Leukemia Cells

Niels Franke, MD, Gertjan J.L. Kaspers, MD PhD, Yehuda G Assaraf, PhD, Johan Van Meerloo, MSc, Denise Niewerth, PhD, Terzah M. Horton, MD PhD, Wee Joo Chng, MD PhD, Chonglei Bi, B.S, Rene X. Menezes, PhD, Renée J. Musters, PhD, Pino J. Poddighe, PhD, Floortje Kessler, Serge Smeets, PhD, Bauke Ylstra, PhD, Sonja Zweegman, MD PhD, Gerrit Jansen, PhD, Jacqueline Cloos, PhD

Blood (2015) 126 (23): 3712.

https://doi.org/10.1182/blood.V126.23.3712.3712

Published: 2015

Journal Articles

The Relevance of Stem Cell Load at Diagnosis for the Development of Relapse in Pediatric Acute Myeloid Leukemia

Dirkje W. Hanekamp, Barbara Denys, Gertjan J.L. Kaspers, MD PhD, Jeroen G. te Marvelde, Gerrit Jan Schuurhuis, PhD, Valerie De Haas, MD PhD, Barbara De Moerloose, MD PhD, Eveline S. de Bont, Anja de Jong, Jan Philippé, MD PhD, Jacqueline Cloos, PhD, Vincent H.J. van der Velden, PhD

Blood (2015) 126 (23): 2584.

https://doi.org/10.1182/blood.V126.23.2584.2584

Published: 2015

Journal Articles

Phase II Study on Bortezomib (BTZ) in Multiple Relapsed or Refractory Pediatric Acute Lymphoblastic Leukemia (rALL): High Response Rate with a Modestly Intensive Regimen Including BTZ, Not Related to Pharmacokinetics

Blood (2015) 126 (23): 2501.

https://doi.org/10.1182/blood.V126.23.2501.2501

Published: 2015

Journal Articles

Predictors of Early Death in Childhood Acute Promyelocytic Leukemia: Results of an International Retrospective Study

Oussama Abla, MD, Raul C. Ribeiro, MD, Anna Maria Testi, MD, Pau Montesinos Fernández, MD, Ursula Creutzig, MD, Lillian Sung, MD PhD, Giancarlo Di Giuseppe, BSc, Derek Stephens, MSc, Henrik Hasle, MD PhD, Gertjan J.L. Kaspers, MD PhD, Luciano Dalla-Pozza, MB BS FRACP, Alvaro Lassaletta, MD, Martin S. Tallman, MD, Franco Locatelli, MD, Dirk Reinhardt, MD, Johann Hitzler, MD FRCP (C), FAAP, Miguel A. Sanz, MD PhD

Blood (2015) 126 (23): 172.

https://doi.org/10.1182/blood.V126.23.172.172

Published: 2015

Journal Articles

Frequency and Prognostic Relevance of Gene Mutations in Pediatric AML Patients At First Relapse.

Costa Bachas, MSc, Gerrit Jan Schuurhuis, PhD, Dirk Reinhardt, MD, Ursula Creutzig, MD, PhD, Zinia J. Kwidama, BSc, C. Michel Zwaan, MD, PhD, Marry M. van den Heuvel-Eibrink, Evelina S De Bont, MD, PhD, Sara Elitzur, MD, Carmelo Rizzari, MD, PhD, Valérie de Haas, MD, PhD, Martin Zimmermann, Jacqueline Cloos, PhD, Gertjan J.L. Kaspers, MD, PhD

Blood (2012) 120 (21): 2480.

https://doi.org/10.1182/blood.V120.21.2480.2480

Published: 2012

Journal Articles

Harnessing Gene Expression Profiles for the Identification of Drug Resistance Genes in Pediatric AML

Costa Bachas, MSc, Gerrit Jan Schuurhuis, PhD, C. Michel Zwaan, MD, PhD, Marry M. van den Heuvel-Eibrink, Monique L. Den Boer, PhD, Zinia J. Kwidama, BSc, Evelina S. De Bont, MD, PhD, Dirk Reinhardt, MD, Ursula Creutzig, MD, PhD, Valérie de Haas, MD, PhD, Yehuda Assaraf, PhD, Gertjan J.L. Kaspers, MD, PhD, Jacqueline Cloos, PhD

Blood (2012) 120 (21): 283.

https://doi.org/10.1182/blood.V120.21.283.283

Published: 2012

Journal Articles

Telomere Length and Telomerase Complex Mutations in Pediatric Acute Myeloid Leukemia

Anna M. Aalbers, Rodrigo T. Calado, Neal S. Young, Christian M. Zwaan, Colin O. Wu, Sachiko Kajigaya, PhD, Eva A. Coenen, André Baruchel, Karin Geleijns, Valerie de Haas, Gertjan J.L. Kaspers, MD, PhD, Taco W. Kuijpers, Dirk Reinhardt, MD, Jan Trka, MD, PhD, Martin Zimmermann, Rob Pieters, MD, PhD, Vincent H.J. van der Velden, Marry M. van den Heuvel-Eibrink

Blood (2012) 120 (21): 1482.

https://doi.org/10.1182/blood.V120.21.1482.1482

Published: 2012

Journal Articles

Translocation t(6;9)(p22;q34)/DEK-NUP214 rearranged Pediatric AML: A Retrospective International Study

Blood (2012) 120 (21): 538.

https://doi.org/10.1182/blood.V120.21.538.538

Published: 2012

Journal Articles

Interferon-γ-Induced Upregulation of Immunoproteasome Subunit Assembly Overcomes Bortezomib Resistance of Leukemia Cell Lines Harbouring Bortezomib-Induced Mutations in Constitutive PSMB5

Denise Niewerth, MSc, Niels Franke, MD, Gerrit Jansen, PhD, Yehuda Assaraf, PhD, Johan van Meerloo, MSc, Christopher J Kirk, PhD, Sonja Zweegman, MD, PhD, Gertjan J.L. Kaspers, MD, PhD, Jacqueline Cloos, PhD

Blood (2012) 120 (21): 1346.

https://doi.org/10.1182/blood.V120.21.1346.1346

Published: 2012

Journal Articles

Characterization of CEBPA Mutations and Promoter Hypermethylation in Pediatric Acute Myeloid Leukemia.

Iris H.I.M. Hollink, MD, Marry M. van den Heuvel-Eibrink, MD, PhD, Susan T.C.J.M. Arentsen-Peters, Martin Zimmermann, PhD, Justine K. Peeters, PhD, Peter J. Valk, PhD, Brian V. Balgobind, MD, Gertjan J.L. Kaspers, MD, PhD, Evelina S.J.M. de Bont, MD, PhD, Siebold S.N. de Graaf, MD, PhD, Jan Trka, PhD, Jan Stary, MD, PhD, Jean-Michel Cayuela, PhD, Andre Baruchel, MD, PhD, Ursula Creutzig, MD, PhD, Dirk Reinhardt, MD, PhD, Rob Pieters, MD, PhD, C. Michel Zwaan, MD, PhD

Blood (2009) 114 (22): 1605.

https://doi.org/10.1182/blood.V114.22.1605.1605

Published: 2009

NARROW

Cumulative Incidence of Blood Stream Infections during Acute Myeloid Leukemia Treatment in the Netherlands: A 15-Year Overview

Obesity Is Associated with Favorable Cytogenetic Abnormalities in Pediatric Acute Myeloid Leukemia

A Dynamic Epigenetic Landscape in Genetic and Immunophenotypic Stable Pediatric AML

Differences in Infection Prophylaxis between Pediatric AML Study Groups within the International BFM Study Group

Targeted Deep Sequencing of GATA1 more Sensitively Identifies Transient Myeloproliferative Disorder in Neonates with Down Syndrome

Characteristics and Outcomes of Pediatric Patients with t(16;16)-AML: Results of a Case Series By the International BFM Study Group

The Prognostic Impact of Cytogenetics and Karyotype Changes in Pediatric Patients with Relapsed Acute Myeloid Leukemia: A Retrospective Cohort Study within the Relapsed AML 2001/01 Study

Excellent Outcome in Pediatric AML with Response Guided Chemotherapy without Allogeneic HSCT in First Complete Remission: Results from Protocol DB-AML01

Risk-Group Stratified and Minimal Residual Disease (MRD)-Guided Treatment with Extended ATRA and Reduced-Anthracycline Chemotherapy in Childhood Acute Promyelocytic Leukemia (APL): Results from ICC APL Study 01 (NCT01226303; EudraCT 2008-002311-40)

Marcks Marks Resistance to Proteasome Inhibitors: Exocytosis of Polyubiquitinated Proteins in Bortezomib-Resistant Leukemia Cells

The Relevance of Stem Cell Load at Diagnosis for the Development of Relapse in Pediatric Acute Myeloid Leukemia

Phase II Study on Bortezomib (BTZ) in Multiple Relapsed or Refractory Pediatric Acute Lymphoblastic Leukemia (rALL): High Response Rate with a Modestly Intensive Regimen Including BTZ, Not Related to Pharmacokinetics

Predictors of Early Death in Childhood Acute Promyelocytic Leukemia: Results of an International Retrospective Study

Low Levels of Mir-151-5p and Mir-451 Predict Relapse in Pediatric B-Lineage Acute Lymphoblastic Leukemia.

Frequency and Prognostic Relevance of Gene Mutations in Pediatric AML Patients At First Relapse.

Harnessing Gene Expression Profiles for the Identification of Drug Resistance Genes in Pediatric AML

Telomere Length and Telomerase Complex Mutations in Pediatric Acute Myeloid Leukemia

Translocation t(6;9)(p22;q34)/DEK-NUP214 rearranged Pediatric AML: A Retrospective International Study

Interferon-γ-Induced Upregulation of Immunoproteasome Subunit Assembly Overcomes Bortezomib Resistance of Leukemia Cell Lines Harbouring Bortezomib-Induced Mutations in Constitutive PSMB5

Characterization of CEBPA Mutations and Promoter Hypermethylation in Pediatric Acute Myeloid Leukemia.

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American Society of Hematology

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American Society of Hematology

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