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Journal Articles

A Predictive Score Based on Cytokines, CD4/CD8 Ratio and Age Predicts Hematological Neoplasm-Associated Hemophagocytic Lymphohistiocytosis (H-HLH)

Coralie Bloch, Nanthara Sritharan, Jean-Philippe Jais, Marine Gil, Genevieve de Saint-Basile, Olivier Hermine

Blood (2023) 142 (Supplement 1): 1164.

https://doi.org/10.1182/blood-2023-181748

Published: 2023

Journal Articles

Hematological Involvement in Childhood Langerhans Cell Histiocytosis: A Cohort Study of 303 Patients

Blood (2023) 142 (Supplement 1): 4573.

https://doi.org/10.1182/blood-2023-184588

Published: 2023

Journal Articles

Functional and genetic testing in adults with HLH reveals an inflammatory profile rather than a cytotoxicity defect

Julien Carvelli, Christelle Piperoglou, Catherine Farnarier, Frédéric Vely, Karin Mazodier, Sandra Audonnet, Patrick Nitschke, Christine Bole-Feysot, Mohamed Boucekine, Audrey Cambon, Mohamed Hamidou, Jean-Robert Harle, Geneviève de Saint Basile, Gilles Kaplanski

Blood (2020) 136 (5): 542–552.

https://doi.org/10.1182/blood.2019003664

Published: 2020

Includes: Supplemental data

Journal Articles

HAVCR2 mutations are associated with severe hemophagocytic syndrome in subcutaneous panniculitis-like T-cell lymphoma

Gabrielle Sonigo, Maxime Battistella, Marie Beylot-Barry, Saskia Ingen-Housz-Oro, Nathalie Franck, Stéphane Barete, Serge Boulinguez, Olivier Dereure, Nathalie Bonnet, Gérard Socié, Pauline Brice, Olivia Boccara, Christine Bodemer, Henri Adamski, Michel D’Incan, Nicolas Ortonne, Sylvie Fraitag, Florence Brunet-Possenti, Stephane Dalle, Felipe Suarez, Ambroise Marçais, François Skowron, Dima Haidar, Eve Maubec, Gerome Bohelay, Liliane Laroche, Antoine Mahé, Elodie Birckel, Jean-David Bouaziz, Isabelle Brocheriou, Romain Dubois, Sarah Faiz, Jehane Fadlallah, Caroline Ram-Wolff, Agnes Carlotti, Guido Bens, Brigitte Balme, Beatrice Vergier, Sara Laurent-Roussel, Lydia Deschamps, Olivier Carpentier, Philippe Moguelet, Genevieve Herve, François Comoz, François Le Gall, Guy Leverger, Antoine Finon, Olivier Augereau, Claire Bléchet, Remy Kerdraon, Laurence Lamant, Emilie Tournier, Frédéric Franck, Valérie Costes-Martineau, Vanessa Szablewski, Sebastien Taix, Isabelle Beschet, Frédéric Guerin, Fernando E. Sepulveda, Martine Bagot, Genevieve de Saint Basile, David Michonneau, Adele de Masson

Blood (2020) 135 (13): 1058–1061.

https://doi.org/10.1182/blood.2019003811

Published: 2020

Includes: Supplemental data

Journal Articles

Alemtuzumab as First Line Treatment in Children with Familial Lymphohistiocytosis

Blood (2019) 134 (Supplement_1): 80.

https://doi.org/10.1182/blood-2019-124477

Published: 2019

Journal Articles

Genetic of Sporadic Hemophagocytic Lymphohistiocytosis

Coralie Bloch, MD PhD, Jean-Philippe Jais, MD PhD, Marine Gil, Marouane Boubaya, PhD, Felipe Suarez, MD PhD, Brigitte Bader-Meunier, MD, Nizar Malhaoui, MD PhD, Alain Fischer, MD PhD, Genevieve de Saint Basile, MD PhD, Olivier Hermine, MD PhD

Blood (2019) 134 (Supplement_1): 82.

https://doi.org/10.1182/blood-2019-129743

Published: 2019

Journal Articles

Germline TIM-3 Mutations Characterize Sub-Cutaneous Panniculitis T-Cell Lymphomas with Hemophagocytic Lymphohistiocytic Syndrome

Blood (2018) 132 (Supplement 1): 1569.

https://doi.org/10.1182/blood-2018-99-120297

Published: 2018

Journal Articles

Gene-corrected human Munc13-4–deficient CD8 + T cells can efficiently restrict EBV-driven lymphoproliferation in immunodeficient mice

Tayebeh Soheili, Julie Rivière, Ida Ricciardelli, Amandine Durand, Els Verhoeyen, Anne-Céline Derrien, Chantal Lagresle-Peyrou, Geneviève de Saint Basile, François-Loïc Cosset, Persis Amrolia, Isabelle André-Schmutz, Marina Cavazzana

Blood (2016) 128 (24): 2859–2862.

https://doi.org/10.1182/blood-2016-07-729871

Published: 2016

Includes: Supplemental data

Journal Articles

Therapeutic effect of JAK1/2 blockade on the manifestations of hemophagocytic lymphohistiocytosis in mice

Sophia Maschalidi, Fernando E. Sepulveda, Alexandrine Garrigue, Alain Fischer, Geneviève de Saint Basile

Blood (2016) 128 (1): 60–71.

https://doi.org/10.1182/blood-2016-02-700013

Published: 2016

Includes: Supplemental data

Journal Articles

Polygenic mutations in the cytotoxicity pathway increase susceptibility to develop HLH immunopathology in mice

Fernando E. Sepulveda, Alexandrine Garrigue, Sophia Maschalidi, Meriem Garfa-Traore, Gaël Ménasché, Alain Fischer, Geneviève de Saint Basile

Blood (2016) 127 (17): 2113–2121.

https://doi.org/10.1182/blood-2015-12-688960

Published: 2016

Includes: Supplemental data

Journal Articles

A novel immunoregulatory role for NK-cell cytotoxicity in protection from HLH-like immunopathology in mice

Fernando E. Sepulveda, Sophia Maschalidi, Christian A. J. Vosshenrich, Alexandrine Garrigue, Mathieu Kurowska, Gael Ménasche, Alain Fischer, James P. Di Santo, Geneviève de Saint Basile

Blood (2015) 125 (9): 1427–1434.

https://doi.org/10.1182/blood-2014-09-602946

Published: 2015

Includes: Supplemental data

Journal Articles

Stem Cell and T-Cell Gene Therapy Using SIN-Lentiviral Vector In Type 3 Familial Hemophagocytic Lymphohistiocytosis

Julie Rivière, Tayebeh Soheili, Els Verhoeyen, Anne Galy, Geneviève de Saint Basile, Alain Fischer, Isabelle Andre-Schmutz, Marina Cavazzana

Blood (2013) 122 (21): 4214.

https://doi.org/10.1182/blood.V122.21.4214.4214

Published: 2013

Journal Articles

The risk of hemophagocytic lymphohistiocytosis in Hermansky-Pudlak syndrome type 2

Blood (2013) 121 (15): 2943–2951.

https://doi.org/10.1182/blood-2012-10-463166

Published: 2013

Includes: Supplemental data

Journal Articles

Characteristics and outcome of early-onset, severe forms of Wiskott-Aldrich syndrome

Nizar Mahlaoui, Isabelle Pellier, Cécile Mignot, Jean-Philippe Jais, Chrystèle Bilhou-Nabéra, Despina Moshous, Bénédicte Neven, Capucine Picard, Geneviève de Saint-Basile, Marina Cavazzana-Calvo, Stéphane Blanche, Alain Fischer

Blood (2013) 121 (9): 1510–1516.

https://doi.org/10.1182/blood-2012-08-448118

Published: 2013

Includes: Supplemental data

Journal Articles

Distinct severity of HLH in both human and murine mutants with complete loss of cytotoxic effector PRF1, RAB27A, and STX11

Fernando E. Sepulveda, Franck Debeurme, Gaël Ménasché, Mathieu Kurowska, Marjorie Côte, Jana Pachlopnik Schmid, Alain Fischer, Geneviève de Saint Basile

Blood (2013) 121 (4): 595–603.

https://doi.org/10.1182/blood-2012-07-440339

Published: 2013

Includes: Supplemental data

Journal Articles

Terminal transport of lytic granules to the immune synapse is mediated by the kinesin-1/Slp3/Rab27a complex

Mathieu Kurowska, Nicolas Goudin, Nadine T. Nehme, Magali Court, Jérôme Garin, Alain Fischer, Geneviève de Saint Basile, Gaël Ménasché

Blood (2012) 119 (17): 3879–3889.

https://doi.org/10.1182/blood-2011-09-382556

Published: 2012

Includes: Supplemental data

Journal Articles

MST1 mutations in autosomal recessive primary immunodeficiency characterized by defective naive T-cell survival

Nadine T. Nehme, Jana Pachlopnik Schmid, Franck Debeurme, Isabelle André-Schmutz, Annick Lim, Patrick Nitschke, Frédéric Rieux-Laucat, Patrick Lutz, Capucine Picard, Nizar Mahlaoui, Alain Fischer, Geneviève de Saint Basile

Blood (2012) 119 (15): 3458–3468.

https://doi.org/10.1182/blood-2011-09-378364

Published: 2012

Includes: Supplemental data

Journal Articles

Control of Plasmodium falciparum erythrocytic cycle: γδ T cells target the red blood cell–invasive merozoites

Giulia Costa, Séverine Loizon, Marianne Guenot, Iulia Mocan, Franck Halary, Geneviève de Saint-Basile, Vincent Pitard, Julie Déchanet-Merville, Jean-François Moreau, Marita Troye-Blomberg, Odile Mercereau-Puijalon, Charlotte Behr

Blood (2011) 118 (26): 6952–6962.

https://doi.org/10.1182/blood-2011-08-376111

Published: 2011

Includes: Supplemental data

Journal Articles

The munc13-4–rab27 complex is specifically required for tethering secretory lysosomes at the plasma membrane

Edo D. Elstak, Maaike Neeft, Nadine T. Nehme, Jarno Voortman, Marc Cheung, Monireh Goodarzifard, Hans C. Gerritsen, Paul M. P. van Bergen en Henegouwen, Isabelle Callebaut, Geneviève de Saint Basile, Peter van der Sluijs

Blood (2011) 118 (6): 1570–1578.

https://doi.org/10.1182/blood-2011-02-339523

Published: 2011

Includes: Multimedia, Supplemental data

Journal Articles

Clinical similarities and differences of patients with X-linked lymphoproliferative syndrome type 1 (XLP-1/SAP deficiency) versus type 2 (XLP-2/XIAP deficiency)

Blood (2011) 117 (5): 1522–1529.

https://doi.org/10.1182/blood-2010-07-298372

Published: 2011

Includes: Supplemental data

NARROW

A Predictive Score Based on Cytokines, CD4/CD8 Ratio and Age Predicts Hematological Neoplasm-Associated Hemophagocytic Lymphohistiocytosis (H-HLH)

Hematological Involvement in Childhood Langerhans Cell Histiocytosis: A Cohort Study of 303 Patients

Functional and genetic testing in adults with HLH reveals an inflammatory profile rather than a cytotoxicity defect

HAVCR2 mutations are associated with severe hemophagocytic syndrome in subcutaneous panniculitis-like T-cell lymphoma

Alemtuzumab as First Line Treatment in Children with Familial Lymphohistiocytosis

Genetic of Sporadic Hemophagocytic Lymphohistiocytosis

Germline TIM-3 Mutations Characterize Sub-Cutaneous Panniculitis T-Cell Lymphomas with Hemophagocytic Lymphohistiocytic Syndrome

Gene-corrected human Munc13-4–deficient CD8 + T cells can efficiently restrict EBV-driven lymphoproliferation in immunodeficient mice

Therapeutic effect of JAK1/2 blockade on the manifestations of hemophagocytic lymphohistiocytosis in mice

Polygenic mutations in the cytotoxicity pathway increase susceptibility to develop HLH immunopathology in mice

A novel immunoregulatory role for NK-cell cytotoxicity in protection from HLH-like immunopathology in mice

Stem Cell and T-Cell Gene Therapy Using SIN-Lentiviral Vector In Type 3 Familial Hemophagocytic Lymphohistiocytosis

The risk of hemophagocytic lymphohistiocytosis in Hermansky-Pudlak syndrome type 2

Characteristics and outcome of early-onset, severe forms of Wiskott-Aldrich syndrome

Distinct severity of HLH in both human and murine mutants with complete loss of cytotoxic effector PRF1, RAB27A, and STX11

Terminal transport of lytic granules to the immune synapse is mediated by the kinesin-1/Slp3/Rab27a complex

MST1 mutations in autosomal recessive primary immunodeficiency characterized by defective naive T-cell survival

Control of Plasmodium falciparum erythrocytic cycle: γδ T cells target the red blood cell–invasive merozoites

The munc13-4–rab27 complex is specifically required for tethering secretory lysosomes at the plasma membrane

Clinical similarities and differences of patients with X-linked lymphoproliferative syndrome type 1 (XLP-1/SAP deficiency) versus type 2 (XLP-2/XIAP deficiency)

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American Society of Hematology

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American Society of Hematology

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