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Journal Articles

The Akt pathway regulates survival and homing in Waldenstrom macroglobulinemia

Blood (2007) 110 (13): 4417–4426.

https://doi.org/10.1182/blood-2007-05-092098

Published: 2007

Journal Articles

Protein kinase C inhibitor enzastaurin induces in vitro and in vivo antitumor activity in Waldenström macroglobulinemia

Anne-Sophie Moreau, Xiaoying Jia, Hai T. Ngo, Xavier Leleu, Garrett O'Sullivan, Yazan Alsayed, Alexey Leontovich, Klaus Podar, Jeffrey Kutok, John Daley, Suzan Lazo-Kallanian, Evdoxia Hatjiharissi, Marc S. Raab, Lian Xu, Steven P. Treon, Teru Hideshima, Kenneth C. Anderson, Irene M. Ghobrial

Blood (2007) 109 (11): 4964–4972.

https://doi.org/10.1182/blood-2006-10-054577

Published: 2007

Journal Articles

Novel Agent Perifosine Enhances Antitumor Activity of Bortezomib, Rituximab and Other Conventional Therapies in Waldenstrom’s Macroglobulinemia.

Xavier Leleu, MD, Garrett O’Sullivan, Xiaoying Jia, Anne-Sophie Moreau, MD, Hai Ngo, Evdoxia Hatjiharisi, MD, Hiroshi Yasui, Zachary Hunter, Yu-Tsu Tai, PhD, Judith Runnels, PhD, Steven Treon, MD, Teru Hideshima, MD, Kenneth Anderson, MD, Irene Ghobrial, MD

Blood (2006) 108 (11): 2517.

https://doi.org/10.1182/blood.V108.11.2517.2517

Published: 2006

Journal Articles

Abnormal Expression of TRAF Adapter Proteins in Waldenstrom’s Macroglobulinemia.

Xavier Leleu, MD, Lian Xu, Zachary R. Hunter, Anne-Sophie Moreau, MD, Xiaoying Jia, Garrett O’Sullivan, Vinod Bakthavachalam, Allen W. Ho, Evdoxia Hatjiharissi, MD, Hai T. N’Go, Daniel D. Santos, MD, Kelly O’Connor, Robert Manning, Jacob Soumerai, Christopher Patterson, Irene M. Ghobrial, MD, Steven P. Treon, MD

Blood (2006) 108 (11): 4640.

https://doi.org/10.1182/blood.V108.11.4640.4640

Published: 2006

Journal Articles

Analysis of Chemokine and Adhesion Markers in Waldenstrom Macroglobulinemia.

Hai T. Ngo, Xavier Leleu, MD, Anne-Sophie Moreau, MD, Evdoxia Hatjiharissi, MD, Xiaoying Jia, Garrett O’Sullivan, Judith Runnels, PhD, Rose Villarreal, Zachary Hunter, Steven Treon, MD,PhD, Teru Hideshima, MD, Kenneth Anderson, MD, Irene Ghobrial, MD

Blood (2006) 108 (11): 4653.

https://doi.org/10.1182/blood.V108.11.4653.4653

Published: 2006

Journal Articles

The Combination of the mTOR Inhibitor Rapamycin and Proteasome Inhibitor Bortezomib Is Synergistic In Vitro in Multiple Myeloma.

Garrett O’Sullivan, Xavier Leleu, MD, Xiaoying Jia, Evdoxia Hatjiharisi, MD, Hai Ngo, Anne-Sophie Moreau, MD, Yu-Tsu Tai, PhD, Douglas McMillin, Constantine Mitsiades, MD, Noopur Raje, MD, Teru Hideshima, MD, Robert Schlossman, MD, Paul Richardson, MD, Nikhil Munshi, MD, Kenneth Anderson, MD, Irene Ghobrial, MD

Blood (2006) 108 (11): 3495.

https://doi.org/10.1182/blood.V108.11.3495.3495

Published: 2006

Journal Articles

The Proteasome Inhibitor NPI-0052 in Combination with Bortezomib Induces Antitumor Activity in Waldenstrom Macroglobulinemia.

Xiaoying Jia, Xavier Leleu, MD, Anne-Sophie Moreau, MD, Evdoxia Hatjiharisi, MD, Hai Ngo, Garrett O’Sullivan, Douglas McMillin, PhD, Steven Treon, MD, Constantine Mitsiades, MD, Teru Hideshima, MD, Michael Palladino, Kenneth Anderson, MD, Dharminder Chauhan, PhD, Irene Ghobrial, MD

Blood (2006) 108 (11): 4746.

https://doi.org/10.1182/blood.V108.11.4746.4746

Published: 2006

Journal Articles

Perifosine, an Oral Bioactive Novel Akt Inhibitor, Induces In Vitro and In Vivo Antitumor Activity in Waldenstrom Macroglobulinemia.

Xavier Leleu, MD, Xiaoying Jia, Anne-Sophie Moreau, MD, Evdoxia Hatjiharisi, MD, Hai Ngo, Garrett O’Sullivan, Daisy Moreno, Tanyel Kiziltepe, PhD, Enrique Ocio, MD, Allen Ho, MD, Thierry Facon, MD, Steven Treon, MD, Teru Hideshima, MD, Kenneth Anderson, MD, Irene Ghobrial, MD

Blood (2006) 108 (11): 2488.

https://doi.org/10.1182/blood.V108.11.2488.2488

Published: 2006

Journal Articles

The Selective Protein Kinase CB Inhibitor, Enzastaurin, Induces In Vitro and In Vivo Antitumor Activity in Waldenstrom’s Macroglobulinemia.

Anne-Sophie Moreau, MD, Xiaoying Jia, Garrett O’Sullivan, Xavier Leleu, MD, Klaus Podar, MD, John Daley, Suzan Lalo, Evdoxia Hatjiharisi, MD, Hai Ngo, Mark Raab, MD, Jean-Claude D’Halluin, PhD, Thierry Facon, MD, Teru Hideshima, MD PhD, Steven Treon, MD PhD, Kenneth Anderson, MD, Irene Ghobrial, MD

Blood (2006) 108 (11): 2496.

https://doi.org/10.1182/blood.V108.11.2496.2496

Published: 2006

Journal Articles

Molecular Mechanisms Regulating Resistance to the Akt Inhibitor Perifosine in Waldenstrom’s Macroglobulinemia, the Role of the ERK and PKC Pathways.

Xavier Leleu, MD, Hai Ngo, Xiaoying Jia, Anne-Sophie Moreau, MD, Evdoxia Hatjiharisi, MD, Ruben Carrasco, MD, Garrett O’Sullivan, Judith Runnels, PhD, Yu-Tsu Tai, PhD, Steven Treon, MD, Teru Hideshima, MD, Kenneth Anderson, MD, Irene Ghobrial, MD

Blood (2006) 108 (11): 2416.

https://doi.org/10.1182/blood.V108.11.2416.2416

Published: 2006

Journal Articles

The PI3K/Akt Pathway Is an Important Regulator of Homing and Adhesion in Waldenstrom’s Macroglobulinemia.

Xavier Leleu, MD, Hai Ngo, Judy Runnels, PhD, Costas Pitsillides, Joel Spencer, Anne-Sophie Moreau, MD, Evdoxia Hatjiharisi, MD, Xiaoying Jia, Garrett O’Sullivan, Steven Treon, MD, Teru Hideshima, MD, Charles Lin, PhD, Kenneth Anderson, MD, Irene Ghobrial, MD

Blood (2006) 108 (11): 2417.

https://doi.org/10.1182/blood.V108.11.2417.2417

Published: 2006

Journal Articles

The CXCR4/SDF-1 Axis Regulates Migration and Adhesion in Waldenstrom Macroglobulinemia.

Hai Ngo, Evdoxia Hatjiharissi, MD, Xavier Leleu, MD, Judith Runnels, PhD, Anne-Sophie Moreau, MD, Xiaoying Jia, Garrett O’Sullivan, Daniel Santos, MD, Lian Xu, Steven Treon, Teru Hideshima, MD, Kenneth Anderson, MD, Irene Ghobrial, MD

Blood (2006) 108 (11): 2418.

https://doi.org/10.1182/blood.V108.11.2418.2418

Published: 2006

Journal Articles

Serum Free Light Chain in Waldenstrom Macroglobulinemia.

Anne-Sophie Moreau, MD, Xavier Leleu, MD, Robert Manning, Valérie Coiteux, MD, Stéphane Darre, MD, Evdoxia Hatjiharisi, MD, Zachary Hunter, Xiaoying Jia, Hai Ngo, Garrett O’Sullivan, Daniel Santos, MD, Steven Treon, MD, Thierry Facon, MD, Kenneth Anderson, MD, Irene Ghobrial, MD

Blood (2006) 108 (11): 2420.

https://doi.org/10.1182/blood.V108.11.2420.2420

Published: 2006

NARROW

The Akt pathway regulates survival and homing in Waldenstrom macroglobulinemia

Protein kinase C inhibitor enzastaurin induces in vitro and in vivo antitumor activity in Waldenström macroglobulinemia

Novel Agent Perifosine Enhances Antitumor Activity of Bortezomib, Rituximab and Other Conventional Therapies in Waldenstrom’s Macroglobulinemia.

Abnormal Expression of TRAF Adapter Proteins in Waldenstrom’s Macroglobulinemia.

Analysis of Chemokine and Adhesion Markers in Waldenstrom Macroglobulinemia.

The Combination of the mTOR Inhibitor Rapamycin and Proteasome Inhibitor Bortezomib Is Synergistic In Vitro in Multiple Myeloma.

The Proteasome Inhibitor NPI-0052 in Combination with Bortezomib Induces Antitumor Activity in Waldenstrom Macroglobulinemia.

Perifosine, an Oral Bioactive Novel Akt Inhibitor, Induces In Vitro and In Vivo Antitumor Activity in Waldenstrom Macroglobulinemia.

The Selective Protein Kinase CB Inhibitor, Enzastaurin, Induces In Vitro and In Vivo Antitumor Activity in Waldenstrom’s Macroglobulinemia.

Molecular Mechanisms Regulating Resistance to the Akt Inhibitor Perifosine in Waldenstrom’s Macroglobulinemia, the Role of the ERK and PKC Pathways.

The PI3K/Akt Pathway Is an Important Regulator of Homing and Adhesion in Waldenstrom’s Macroglobulinemia.

The CXCR4/SDF-1 Axis Regulates Migration and Adhesion in Waldenstrom Macroglobulinemia.

Serum Free Light Chain in Waldenstrom Macroglobulinemia.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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