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Journal Articles

Aberrant Activity of the Calcium Sensor STIM1 Underlies Congenital Platelet Disorders and Myeloproliferative Neoplasms

Molly Brakhane, Vittorio Abbonante, Angelo B. A. Laranjeira, Christian Di Buduo, Brooke Sadler, Katrina Ashworth, Tim Kong, Fan He, Mary C. Fulbright, Dong Chen, Regina Clemens, Elena Pegoraro, Michele P. Lambert, Kandace Gollomp, Jorge Di Paola, Alessandra Balduini, Stephen T. Oh
Journal: Blood
Blood (2023) 142 (Supplement 1): 995.
https://doi.org/10.1182/blood-2023-186413
Published: 2023
Journal Articles

Galectin-1 Fuels Monocyte-Driven Hyperinflammation and Represents a Novel Therapeutic Target in Myeloproliferative Neoplasms

Fan He, Tim Kong, Shuyang Lin, Mary C. Fulbright, Angelo B. A. Laranjeira, Daniel A.C. Fisher, Maggie J Cox, Katrina Ashworth, Jorge Di Paola, Stephen T. Oh
Journal: Blood
Blood (2023) 142 (Supplement 1): 4518.
https://doi.org/10.1182/blood-2023-189252
Published: 2023
Journal Articles

RSK1 Is an Exploitable Dependency in Myeloid Malignancies

Tim Kong, Angelo B. A. Laranjeira, LaYow Yu, Jared Scott Fowles, Daniel A.C. Fisher, Sherwin Ng, Wei Yang, Fan He, Maggie J Cox, Mary C. Fulbright, Stacey L. Rentschler, My-my Huynh, Gerrit Los, Sandra E. Dunn, Grant A Challen, Stephen T. Oh
Journal: Blood
Blood (2023) 142 (Supplement 1): 46.
https://doi.org/10.1182/blood-2023-182320
Published: 2023
Journal Articles

Transcriptional and Metabolic Profiling Reveals Alpha-Ketoglutarate As a Novel Mediator of Aberrant Platelet Activity and Inflammation in Myeloproliferative Neoplasms

Fan He, Angelo BA Laranjeira, Tim Kong, Katrina Bark, Alice Liu, Maggie J. Allen, Daniel AC Fisher, Mary Fulbright, LaYow Yu, Nina M. Lasky, Stephen M. Sykes, Angelo D'Alessandro, Jorge Di Paola, Stephen T Oh
Journal: Blood
Blood (2022) 140 (Supplement 1): 1095–1097.
https://doi.org/10.1182/blood-2022-167786
Published: 2022
Journal Articles

Targeting RSK1-Mediated Dependency and Inflammation in Myeloid Malignancies

Tim Kong, Angelo BA Laranjeira, LaYow Yu, Jared S. Fowles, Fan He, Maggie J. Allen, Stephen T Oh
Journal: Blood
Blood (2022) 140 (Supplement 1): 6724–6725.
https://doi.org/10.1182/blood-2022-164912
Published: 2022
Journal Articles

Comprehensive Profiling of Clinical JAK2 Inhibitors in Myeloproliferative Neoplasms

Tim Kong, LaYow Yu, Angelo BA Laranjeira, Fan He, Maggie J. Allen, Stephen T Oh
Journal: Blood
Blood (2022) 140 (Supplement 1): 3951–3952.
https://doi.org/10.1182/blood-2022-164925
Published: 2022