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Journal Articles

Setbp1 Overexpression Acts in the Place of Class-Defining Somatic Mutations to Drive Mouse and Human FLT3-ITD -Mutant AMLs

Suruchi Pacharne, Oliver M. Dovey, PhD, Jonathan L Cooper, Muxin Gu, Vijay Baskar, PhD, Mathias J Friedrich, Malgorzata Gozdecka, PhD, Sandeep S Rajan, PhD, Etienne De Braekeleer, PhD MSc, Maxim Barenboim, Grace Collord, Hannes Postingl, PhD, Ruben Bautista, Milena Mazan, PhD, Roland Rad, Prof., MD, Konstantinos Tzelepis, Penny Wright, George S. Vassiliou, MD PhD FRCPath, MRCP

Blood (2020) 136 (Supplement 1): 31–32.

https://doi.org/10.1182/blood-2020-141743

Published: 2020

Journal Articles

Pharmacological Inhibition of the RNA m 6 a Writer METTL3 As a Novel Therapeutic Strategy for Acute Myeloid Leukemia

Konstantinos Tzelepis, Etienne De Braekeleer, PhD MSc, Eliza Yankova, PhD, Justyna Rak, PhD, Demetrios Aspris, MSc, Ana Filipa Domingues, PhD, Richard Fosbeary, Alan Hendrick, PhD, Dan Leggate, PhD, Yaara Ofir-Rosenfeld, PhD, Alexandra Sapetschnig, PhD, Cristina Pina, MDDPhil, Mark Albertella, PhD, Wesley Blackaby, PhD, Oliver Rausch, PhD, George S. Vassiliou, FRCPath, MRCP, PhD, Tony Kouzarides, PhD

Blood (2019) 134 (Supplement_1): 403.

https://doi.org/10.1182/blood-2019-127962

Published: 2019

Journal Articles

The Nucleotide Kinase Nadk Is Required for ROS Detoxification and Constitutes a Metabolic Vulnerability of NOTCH1-Driven T-ALL

Etienne De Braekeleer, PhD MSc, Joanne Hsu, BS, Celine Hervieu, MSc, Konstantinos Tzelepis, PhD, Stefano Indraccolo, MD, Alan J. Warren, PhD FRCP, FRCPath, Irmela Jeremias, MD PhD, David Fernandez Antoran, PhD, Phil H Jones, PhD, Margaret A. Goodell, PhD, George S. Vassiliou

Blood (2018) 132 (Supplement 1): 2615.

https://doi.org/10.1182/blood-2018-99-118827

Published: 2018

Journal Articles

High Prevalence of PPM1D Mutations in Therapy-Related AML/MDS Is Due to Context-Specific Clonal Hematopoiesis

Joanne Hsu, BS, Tajhal Dayaram, Ayala Tovy, PhD, Etienne De Braekeleer, PhD MSc, Mira Jeong, PhD, Jason H. Rogers, MS, Feng Wang, PhD, Jianhua Zhang, PhD, Guillermo Garcia-Manero, MD, Hagop M. Kantarjian, MD, George S. Vassiliou, Andrew Futreal, PhD, Lawrence Donehower, Koichi Takahashi, MD, Margaret Goodell, PhD

Blood (2018) 132 (Supplement 1): 746.

https://doi.org/10.1182/blood-2018-99-115007

Published: 2018

Journal Articles

SRPK1 Is a Therapeutic Vulnerability in Acute Myeloid Leukemia through Its Effects on Alternative Isoforms of Epigenetic Regulators Including BRD4

Konstantinos Tzelepis, PhD, Etienne De Braekeleer, PhD, Isaia Barbieri, PhD, Vijay Baskar, PhD, Demetrios Aspris, MSc, Francisco Hermida Prado, PhD, Malgorzata Gozdecka, PhD, Monika Dudek, MSc, Hannes Postingl, PhD, David Bates, PhD, Andrew Bannister, PhD, Brian J.P Huntly, Cristina Pina, MDDPhil, Allan Bradley, PhD, Kosuke Yusa, PhD, Tony Kouzarides, PhD, George S. Vassiliou, MD PhD

Blood (2017) 130 (Supplement 1): 781.

https://doi.org/10.1182/blood.V130.Suppl_1.781.781

Published: 2017

Journal Articles

A Crispr/Cas9 Drop-out Screen Identifies Genome-Wide Genetic Valnerubilities in Acute Myeloid Leukaemia

Blood (2015) 126 (23): 554.

https://doi.org/10.1182/blood.V126.23.554.554

Published: 2015

Journal Articles

New Insights to the MLL Recombinome Including 8 Novel Partner Genes ACTN4, C2CD3, DCP1A, FLNA, LAMC3, LOC100128568, NRIP3, and TNRC18.

Claus Meyer, PhD, Eric Kowarz, PhD, Julia Hofmann, Thomas Fischer, Sara El Ashkar, Andrea Teigler-Schlegel, PhD, Brian Balgobind, MD, Thomas Burmeister, PhD, Etienne De Braekeleer, Eric Delabesse, PhD, Aline Renneville, MD, Theo Dingermann, PhD, Thomas Klingebiel, MD, Rolf Marschalek, PhD

Blood (2008) 112 (11): 2047.

https://doi.org/10.1182/blood.V112.11.2047.2047

Published: 2008

Journal Articles

Novel Spliced MLL Fusions Have Been Identified Involving the MLL Partner Genes ELL, EPS15, MLLT3, and SEPT5.

Claus Meyer, PhD, Eric Kowarz, Wajih Brahim, MD, Renate Grümayer, MD, Raouf Ben-Abdelali, MD, Etienne De Braekeleer, Marc De Braekeleer, PhD, Elizabeth A. Macintyre, PhD, Eric Delabesse, PhD, Theo Dingermann, PhD, Thomas Klingebiel, MD, Rolf Marschalek, PhD

Blood (2007) 110 (11): 978.

https://doi.org/10.1182/blood.V110.11.978.978

Published: 2007

NARROW

Setbp1 Overexpression Acts in the Place of Class-Defining Somatic Mutations to Drive Mouse and Human FLT3-ITD -Mutant AMLs

Pharmacological Inhibition of the RNA m 6 a Writer METTL3 As a Novel Therapeutic Strategy for Acute Myeloid Leukemia

The Nucleotide Kinase Nadk Is Required for ROS Detoxification and Constitutes a Metabolic Vulnerability of NOTCH1-Driven T-ALL

High Prevalence of PPM1D Mutations in Therapy-Related AML/MDS Is Due to Context-Specific Clonal Hematopoiesis

SRPK1 Is a Therapeutic Vulnerability in Acute Myeloid Leukemia through Its Effects on Alternative Isoforms of Epigenetic Regulators Including BRD4

A Crispr/Cas9 Drop-out Screen Identifies Genome-Wide Genetic Valnerubilities in Acute Myeloid Leukaemia

New Insights to the MLL Recombinome Including 8 Novel Partner Genes ACTN4, C2CD3, DCP1A, FLNA, LAMC3, LOC100128568, NRIP3, and TNRC18.

Novel Spliced MLL Fusions Have Been Identified Involving the MLL Partner Genes ELL, EPS15, MLLT3, and SEPT5.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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