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Journal Articles

Correlation between the Degree of Bone Marrow Involvement and the Results of NGS in Plasma Cell Neoplasms

Ekaterina Rebmann Chigrinova, MD PhD, Naomi A. Porret, PhD, Gertrud Wiedemann, PhD, Martin Andres, MD, Yara Banz, MD PhD, Myriam Legros, Matthias Pollak, MD, Elisabeth Oppliger Leibundgut, Thomas Pabst, MD, Ulrike Bacher

Blood (2020) 136 (Supplement 1): 9–10.

https://doi.org/10.1182/blood-2020-142009

Published: 2020

Journal Articles

Characterization of Kinase Activity By Phosphoproteomics in Myeloid Cell Lines for Identification of Driving Oncogenic Pathways

Mahmoud Hallal, Manfred Heller, PhD, Rémy Bruggmann, PhD, Ramanjaneyulu Allam, PhD MSc, BSc, Raphael Jeancourt, PhD, Elisabeth Oppliger Leibundgut, PharmD, Cédric Simillion, PhD, Nicolas Bonadies, MD

Blood (2017) 130 (Supplement 1): 2515.

https://doi.org/10.1182/blood.V130.Suppl_1.2515.2515

Published: 2017

Journal Articles

Dynamics of Telomere Length Reflect the Clonal Suppression Seen with the Telomerase Inhibitor Imetelstat in Patients with Essential Thrombocythemia

Monika Haubitz, PhD, Elisabeth Oppliger Leibundgut, PharmD, Ingrid Helsen, Dania Hiltbrunner, Bart Burington, PhD, Oliver G. Ottmann, MD, Gary Spitzer, MD, Olatoyosi Odenike, MD, Michael A McDevitt, MD PhD, Alexander Röth, MD, David S. Snyder, MD, Gabriela M. Baerlocher, MD

Blood (2016) 128 (22): 1938.

https://doi.org/10.1182/blood.V128.22.1938.1938

Published: 2016

Journal Articles

Dynamics of Mutations in Patients with ET Treated with Imetelstat

Elisabeth Oppliger Leibundgut, PharmD, Monika Haubitz, PhD, Bart Burington, PhD, Oliver G. Ottmann, MD, Gary Spitzer, MD, Olatoyosi Odenike, MD, Michael A McDevitt, MD PhD, Alexander Roeth, MD, David S. Snyder, MD, Gabriela M. Baerlocher, MD

Blood (2015) 126 (23): 57.

https://doi.org/10.1182/blood.V126.23.57.57

Published: 2015

Journal Articles

Impact of comorbidities on overall survival in patients with chronic myeloid leukemia: results of the randomized CML Study IV

Blood (2015) 126 (1): 42–49.

https://doi.org/10.1182/blood-2015-01-617993

Published: 2015

Includes: Supplemental data

Journal Articles

Potential of Digital PCR in CML Calibration

Niels Pallisgaard, Morten T. Andersen, Anni Aggerholm, PhD, Hans Ehrencrona, MD PhD, Beatriz Bellosillo, Elisabeth Oppliger Leibundgut, PharmD

Blood (2014) 124 (21): 1817.

https://doi.org/10.1182/blood.V124.21.1817.1817

Published: 2014

Journal Articles

Monitoring of Calr Allele Burden in Patients with Essential Thrombocythemia Treated with Imetelstat, a Telomerase Inhibitor, Reveals Rapid and Substantial Molecular Responses

Gabriela M. Baerlocher, MD, Monika Haubitz, PhD, Oliver G. Ottmann, MD, Olatoyosi Odenike, MBBS, Alexander Roeth, MD, Michael A McDevitt, MD PhD, Ted Shih, Bart Burington, Dianne Morfeld, Neeru Batra, BS, David Snyder, MD, Elisabeth Oppliger Leibundgut, PharmD

Blood (2014) 124 (21): 408.

https://doi.org/10.1182/blood.V124.21.408.408

Published: 2014

Journal Articles

Successful Engraftment In Children With Severe Aplastic Anemia After Transplantation Of HLA-Identical Hematopoietic Donor Cells With Shorter Telomere Length

Abdulrahman Alsultan, MD, Gabriela M. Baerlocher, MD, Elisabeth Oppliger Leibundgut, PharmD, Sameera AlAfghani, MD, Reem Al-Sudairy, MD, Mohammed Al Balwi, PhD, Mohammed Jarrar, MD

Blood (2013) 122 (21): 2047.

https://doi.org/10.1182/blood.V122.21.2047.2047

Published: 2013

Journal Articles

Imetelstat Rapidly Induces and Maintains Substantial Hematologic and Molecular Responses in Patients with Essential Thrombocythemia (ET) Who Are Refractory or Intolerant to Prior Therapy: Preliminary Phase II Results

Gabriela M. Baerlocher, MD, Elisabeth Oppliger Leibundgut, PharmD, Christina Ayran, Martha Blaney, PharmD, Bart Burington, Ph.D, Dianne Morfeld, Olatoyosi Odenike, MD, Oliver Ottman, MD, Anita Reddy, PhD, Alexander Roeth, MD, Gary Spitzer, MD, Monic J. Stuart, MD, MPH, Srdan Verstovsek, MD, PhD, David S. Snyder, MD

Blood (2012) 120 (21): 179.

https://doi.org/10.1182/blood.V120.21.179.179

Published: 2012

Journal Articles

The Interlaboratory Robustness of Next-Generation Sequencing (IRON) Study Phase II: Deep-Sequencing Analyses of Hematological Malignancies Performed by an International Network Involving 26 Laboratories

Blood (2012) 120 (21): 1399.

https://doi.org/10.1182/blood.V120.21.1399.1399

Published: 2012

Journal Articles

Imetelstat, A Potent Telomerase Inhibitor, Inhibits the Spontaneous Growth of CFU-Meg In Vitro From Essential Thrombocythemia Patients but Not From Healthy Individuals,

Claudio Brunold, Thomas R Braschler, Ning Go, MD, Joi Ninomoto, PharmD, Hooman Kashani, MS DABT, Monic J. Stuart, MD, MPH, Elisabeth Oppliger Leibundgut, PharmD, Gabriela M. Baerlocher, MD

Blood (2011) 118 (21): 3843.

https://doi.org/10.1182/blood.V118.21.3843.3843

Published: 2011

Journal Articles

Interlaboratory Quality Control Round of MPL Mutation Detection in Fourteen European Laboratories: A MPN&MPNr-EuroNet Study,

Naomi A. Porret, PhD, Elisabeth Oppliger Leibundgut, PharmD, Serge Carillo, Bruno Cassinat, PharmD, Francois Girodon, MD, PhD, Éric Lippert, MD, PhD, Valérie Ugo, MD, PhD, Sylvie Hermouet, MD, PhD, Paola Guglielmelli, MD, Jiri Schwarz, MD, PhD, Beatriz Bellosillo, Susanne Schnittger, PhD, Maj K. Westman, Stephane Giraudier, MD, PhD

Blood (2011) 118 (21): 3859.

https://doi.org/10.1182/blood.V118.21.3859.3859

Published: 2011

Journal Articles

Stability of Conversion Factors for BCR-ABL Monitoring -– Implications for the Frequency of Validation Rounds

Martin C. Müller, MD, Umang Munjal, PhD, Philipp Erben, MD, Thomas Lion, MD, PhD, Gerlinde Mitterbauer-Hohendanner, MD, Hakim El Housni, MD, Nancy Boeckx, Renata Zadro, MD, PhD, Jiri Mayer, MD, PhD, Peter Rohon, MD, Jana Rulcova, PhD, Lykke Grubach, Kadri Raudsepp, MD, Veli Kairisto, MD, PhD, Francois-Xavier Mahon, MD, PhD, Claude Preudhomme, MD, Sandrine Hayette, MD, Jean Gabert, MD, Jean-Michel Cayuela, MD, PhD, Christian Thiede, Lars Galonska, MD, Heike Pfeifer, MD, Carsten Hirt, MD, Philippe Schafhausen, MD, Nils von Neuhoff, PhD, Martin Roskos, MD, Christiane Pott, MD, Thoralf Lange, MD, Georg Hess, MD, Susanne Schnittger, PhD, Annika Dufour, MD, Steffen Koschmieder, MD, Frank Stegelmann, MD, Katerina Zoi, MD, PhD, Kostas Stamatopoulos, Hajnalka Andrikovics, MD, PhD, Tali Tohami, MD, PhD, Giovanni Martinelli, MD, Barbara Izzo, PhD, Enrico Gottardi, MD, Mindaugas Stoskus, Dag Andre Nymoen, MD, Tomasz Sacha, MD, Joana Diamond, MD, PhD, Rodica Talmaci, PhD, Andrey Misyurin, MD, Michael V. Dubina, MD, Tadej Pajic, MD, PhD, Josep F. Nomdedeu, MD, Dolors Colomer, MD, PhD, Gisela Barbany-Bustinza, MD, Hans Ehrencrona, MD, Elisabeth Oppliger Leibundgut, PhD, Jeroen Janssen, MD, Vincent H. J. van der elden, MD, Peter J.M. Valk, MD, PhD, Ugur Ozbek, MD, PhD, Lihui Wang, Gareth Gerrard, PhD, Helen E White, PhD, Thomas Schenk, MD, Thomas Ernst, MD, Rüdiger Hehlmann, MD, Giuseppe Saglio, MD, PhD, Andreas Hochhaus, MD, Nicholas C. P. Cross, PhD

Blood (2010) 116 (21): 893.

https://doi.org/10.1182/blood.V116.21.893.893

Published: 2010

Journal Articles

Harmonized Testing for BCR-ABL Kinase Domain Mutations In CML: Results of a Survey and First Control Round within 28 National Reference Laboratories In Europe

Blood (2010) 116 (21): 894.

https://doi.org/10.1182/blood.V116.21.894.894

Published: 2010

Journal Articles

The Extent in Telomere Attrition and the Number of Affected Leukocyte Subsets Distinguishes Patients with Different Myeloproliferative Neoplasms (MPN).

Dirk de Beer, Elke Beutler, Adrian Emanuel Schmidt, Lucie Kopfstein, Elisabeth Oppliger Leibundgut, PharmD, PhD, Gabriela M. Baerlocher, MD

Blood (2009) 114 (22): 1913.

https://doi.org/10.1182/blood.V114.22.1913.1913

Published: 2009

Journal Articles

Cultivation of Megakaryocytes On a Collagen Matrix: A More Sensitive and Reproducible Test for the Diagnosis of Patients with Essential Thrombocythaemia.

Adrian Emanuel Schmidt, MD, Patricia Darlington, Lucie Kopfstein, MD, PhD, Elisabeth Ischi, Elisabeth Oppliger Leibundgut, PharmD, Gabriela Baerlocher, MD

Blood (2009) 114 (22): 4970.

https://doi.org/10.1182/blood.V114.22.4970.4970

Published: 2009

Journal Articles

Distinct Expression and Localization of the Ku Autoantigens in Patients with Chronic Lymphocytic Leukaemia (CLL).

Dirk de Beer, Naomi Porret, Elisabeth Oppliger Leibundgut, PharmD, PhD, Gabriela M. Baerlocher, MD

Blood (2009) 114 (22): 3239.

https://doi.org/10.1182/blood.V114.22.3239.3239

Published: 2009

Journal Articles

NDRG1 Expression Is Inhibited in AML and Its Knockdown Attenuates Neutrophil Differentiation.

Mario P. Tschan, PhD, Deborah Shan, Judith Laedrach, Marianne Eyholzer, Elisabeth Oppliger Leibundgut, PhD, Gabriela Baerlocher, MD, Andreas Tobler, MD, Deborah Stroka, PhD, Martin F. Fey, MD

Blood (2008) 112 (11): 927.

https://doi.org/10.1182/blood.V112.11.927.927

Published: 2008

Journal Articles

A high-resolution allelotype of B-cell chronic lymphocytic leukemia (B-CLL)

Urban Novak, Elisabeth Oppliger Leibundgut, Jörg Hager, Dominique Mühlematter, Martine Jotterand, Celine Besse, Nicolas Leupin, Daniel Ratschiller, Jeanette Papp, Gina Kearsey, Stefan Aebi, Hans Graber, Rolf Jaggi, Jean-Marc Lüthi, Sandrine Meyer-Monard, Mark Lathrop, Andreas Tobler, Martin F. Fey

Blood (2002) 100 (5): 1787–1794.

https://doi.org/10.1182/blood.V100.5.1787.h81702001787_1787_1794

Published: 2002

NARROW

Correlation between the Degree of Bone Marrow Involvement and the Results of NGS in Plasma Cell Neoplasms

Characterization of Kinase Activity By Phosphoproteomics in Myeloid Cell Lines for Identification of Driving Oncogenic Pathways

Dynamics of Telomere Length Reflect the Clonal Suppression Seen with the Telomerase Inhibitor Imetelstat in Patients with Essential Thrombocythemia

Dynamics of Mutations in Patients with ET Treated with Imetelstat

Impact of comorbidities on overall survival in patients with chronic myeloid leukemia: results of the randomized CML Study IV

Potential of Digital PCR in CML Calibration

Monitoring of Calr Allele Burden in Patients with Essential Thrombocythemia Treated with Imetelstat, a Telomerase Inhibitor, Reveals Rapid and Substantial Molecular Responses

Successful Engraftment In Children With Severe Aplastic Anemia After Transplantation Of HLA-Identical Hematopoietic Donor Cells With Shorter Telomere Length

Imetelstat Rapidly Induces and Maintains Substantial Hematologic and Molecular Responses in Patients with Essential Thrombocythemia (ET) Who Are Refractory or Intolerant to Prior Therapy: Preliminary Phase II Results

The Interlaboratory Robustness of Next-Generation Sequencing (IRON) Study Phase II: Deep-Sequencing Analyses of Hematological Malignancies Performed by an International Network Involving 26 Laboratories

Imetelstat, A Potent Telomerase Inhibitor, Inhibits the Spontaneous Growth of CFU-Meg In Vitro From Essential Thrombocythemia Patients but Not From Healthy Individuals,

Interlaboratory Quality Control Round of MPL Mutation Detection in Fourteen European Laboratories: A MPN&MPNr-EuroNet Study,

Stability of Conversion Factors for BCR-ABL Monitoring -– Implications for the Frequency of Validation Rounds

Harmonized Testing for BCR-ABL Kinase Domain Mutations In CML: Results of a Survey and First Control Round within 28 National Reference Laboratories In Europe

The Extent in Telomere Attrition and the Number of Affected Leukocyte Subsets Distinguishes Patients with Different Myeloproliferative Neoplasms (MPN).

Cultivation of Megakaryocytes On a Collagen Matrix: A More Sensitive and Reproducible Test for the Diagnosis of Patients with Essential Thrombocythaemia.

Distinct Expression and Localization of the Ku Autoantigens in Patients with Chronic Lymphocytic Leukaemia (CLL).

NDRG1 Expression Is Inhibited in AML and Its Knockdown Attenuates Neutrophil Differentiation.

A high-resolution allelotype of B-cell chronic lymphocytic leukemia (B-CLL)

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American Society of Hematology

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