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Journal Articles

Macrophage metabolic rewiring improves heme-suppressed efferocytosis and tissue damage in sickle cell disease

Richa Sharma, Ada Antypiuk, S. Zebulon Vance, Deepa Manwani, Quentinn Pearce, James E. Cox, Xiuli An, Karina Yazdanbakhsh, Francesca Vinchi
Journal: Blood
Blood (2023) 141 (25): 3091–3108.
https://doi.org/10.1182/blood.2022018026
Published: 2023
Includes: Supplemental data
Journal Articles

Heme and Iron Aggravate Tissue Damage in Sickle Cell Disease By Driving Macrophage Functional Reprogramming through the Coordinated Suppression of Efferocytosis and Mitochondrial Metabolism

Richa Sharma, S. Zebulon Vance, Ada Antypiuk, Deepa Manwani, Quentinn Pearce, James E. Cox, Xiuli An, Karina Yazdanbakhsh, Francesca Vinchi
Journal: Blood
Blood (2022) 140 (Supplement 1): 2456–2457.
https://doi.org/10.1182/blood-2022-165364
Published: 2022
Journal Articles

Glutamine via α-ketoglutarate dehydrogenase provides succinyl-CoA for heme synthesis during erythropoiesis

Joseph S. Burch, Jason R. Marcero, John Alan Maschek, James E. Cox, Laurie K. Jackson, Amy E. Medlock, John D. Phillips, Harry A. Dailey, Jr
Journal: Blood
Blood (2018) 132 (10): 987–998.
https://doi.org/10.1182/blood-2018-01-829036
Published: 2018
Includes: Supplemental data
Journal Articles

The Role of TCA Cycle Compounds in Erythroid Heme Synthesis and Its Regulation During an Inflammatory Response

Jason R. Marcero, BS, Joseph S. Burch, PhD, John D. Phillips, PhD, James E. Cox, PhD, Laurie K. Jackson, PhD, Harry A. Dailey, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3473.
https://doi.org/10.1182/blood.V130.Suppl_1.3473.3473
Published: 2017
Journal Articles

Ready-to-Use Supplementary Food Supplements Improve Endothelial Function, Hemoglobin and Growth in Tanzanian Children with Sickle Cell Anaemia: The Vascular Function Intervention Study (V-FIT), a Random Order Crossover Trial

Sharon E. Cox, BSc, MSc, PhD, Julie Makani, MD PhD, Gurishaeli Walter, Dip, Selemani Mtunguja, Dip, Beatrice A Kamala, Dip, Elizabeth Ellins, MSc, Charles RJ Newton, MD PhD, Fenella J. Kirkham, MD, Andrew M Prentice, BSc, PhD, Julian P Halcox, MD PhD
Journal: Blood
Blood (2014) 124 (21): 4087.
https://doi.org/10.1182/blood.V124.21.4087.4087
Published: 2014
Journal Articles

Endothelial Function In Tanzanian Children With Sickle Cell Disease: Baseline Results From The Vascular Function Intervention Trial (VFIT)

Sharon E. Cox, BSc, MSc, PhD, Julie Makani, MD, PhD, Elizabeth Ellins, MSc, Gurishaeli Walter, Dip, Selemani Mtunguja, Dip, Fenella J. Kirkham, MD, PhD, Charles RJ Newton, MD, PhD, Andrew M. Prentice, BSc, PhD, Julian P. Halcox, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 984.
https://doi.org/10.1182/blood.V122.21.984.984
Published: 2013
Journal Articles

Zebrafish screen identifies novel compound with selective toxicity against leukemia

Suzanne Ridges, Will L. Heaton, Deepa Joshi, Henry Choi, Anna Eiring, Lance Batchelor, Priya Choudhry, Elizabeth J. Manos, Hossein Sofla, Ali Sanati, Seth Welborn, Archana Agarwal, Gerald J. Spangrude, Rodney R. Miles, James E. Cox, J. Kimble Frazer, Michael Deininger, Kaveri Balan, Matthew Sigman, Markus Müschen, Tatiana Perova, Radia Johnson, Bertrand Montpellier, Cynthia J. Guidos, David A. Jones, Nikolaus S. Trede
Journal: Blood
Blood (2012) 119 (24): 5621–5631.
https://doi.org/10.1182/blood-2011-12-398818
Published: 2012
Includes: Supplemental data
Journal Articles

Hepcidin is the major predictor of erythrocyte iron incorporation in anemic African children

Andrew M. Prentice, Conor P. Doherty, Steven A. Abrams, Sharon E. Cox, Sarah H. Atkinson, Hans Verhoef, Andrew E. Armitage, Hal Drakesmith
Journal: Blood
Blood (2012) 119 (8): 1922–1928.
https://doi.org/10.1182/blood-2011-11-391219
Published: 2012
Journal Articles

Genetics of fetal hemoglobin in Tanzanian and British patients with sickle cell anemia

Brief Report
Julie Makani, Stephan Menzel, Siana Nkya, Sharon E. Cox, Emma Drasar, Deogratius Soka, Albert N. Komba, Josephine Mgaya, Helen Rooks, Nisha Vasavda, Gregory Fegan, Charles R. Newton, Martin Farrall, Swee Lay Thein
Journal: Blood
Blood (2011) 117 (4): 1390–1392.
https://doi.org/10.1182/blood-2010-08-302703
Published: 2011
Journal Articles

Malaria in patients with sickle cell anemia: burden, risk factors, and outcome at the outpatient clinic and during hospitalization

Clinical Trials & Observations
Julie Makani, Albert N. Komba, Sharon E. Cox, Julie Oruo, Khadija Mwamtemi, Jesse Kitundu, Pius Magesa, Stella Rwezaula, Elineema Meda, Josephine Mgaya, Kisali Pallangyo, Emelda Okiro, David Muturi, Charles R. Newton, Gregory Fegan, Kevin Marsh, Thomas N. Williams
Journal: Blood
Blood (2010) 115 (2): 215–220.
https://doi.org/10.1182/blood-2009-07-233528
Published: 2010
Journal Articles

Treatment of chronic granulocytic leukemia with melphalan

T Hauch, G Logue, J Laszlo, E Cox, W Rundles
Journal: Blood
Blood (1978) 51 (4): 571–577.
https://doi.org/10.1182/blood.V51.4.571.571
Published: 1978