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Journal Articles

Exploring the Role of a Novel Tumor Suppressor - OSR2 in T-ALL

Arpan A. Sinha, MBBS, MD, Pilar I. Andrade, MS, Megan Malone-Perez, BS, Syed T Ahmed, MD, J. Kimble Frazer, MD PhD

Blood (2020) 136 (Supplement 1): 26.

https://doi.org/10.1182/blood-2020-142772

Published: 2020

Journal Articles

Deranged Transcription and Replication in MYC-Induced B and T Cell Leukemias

Arpan A. Sinha, MBBS, MD, Pilar I. Andrade, MS, Courtney Sansam, PhD, Megan Malone-Perez, BS, Christopher Sansam, PhD, J. Kimble Frazer, MD PhD

Blood (2020) 136 (Supplement 1): 2.

https://doi.org/10.1182/blood-2020-142890

Published: 2020

Journal Articles

CHD1 - a Novel Epigenetic Regulator in Myeloid Malignancies with a Role in DNA Repair

Arpan Sinha, MBBS, MD, Adriana De La Garza, PhD, Amit Verma, MD, J. Kimble Frazer, MD PhD, Teresa V. Bowman, PhD

Blood (2018) 132 (Supplement 1): 2607.

https://doi.org/10.1182/blood-2018-99-114259

Published: 2018

Journal Articles

Zebrafish screen identifies novel compound with selective toxicity against leukemia

Blood (2012) 119 (24): 5621–5631.

https://doi.org/10.1182/blood-2011-12-398818

Published: 2012

Includes: Supplemental data

Journal Articles

Focal 22q11.22 Loss Combined with IKZF1 Alterations Predict Very Poor Outcome in Childhood Acute Lymphoblastic Leukemia

D. Spencer Mangum, MD, Soheil Shams, PhD, Jonathan M. Downie, BS, Uta von Schwedler, PhD, Vladimir Rodic, PhD, Michael Engel, MD, PhD, Phillip Barnette, MD, J. Kimble Frazer, MD, PhD, Nikolaus Trede, MD, PhD, Dequing Pei, PhD, Cheng Cheng, PhD, Ching-Hon Pui, MD, Stephen P Hunger, MD, Jun J. Yang, PhD, Rodney R. Miles, MD, PhD, Charles G Mullighan, MBBS, MD, FRACP, FRCPA, MSc, Joshua D. Schiffman, MD

Blood (2011) 118 (21): 741.

https://doi.org/10.1182/blood.V118.21.741.741

Published: 2011

Journal Articles

A Novel Dual AXL/Mertk and Aurora Kinase Inhibitor Active Against T Cell Acute Lymphoblastic Leukemia

Anupam Verma, MD, J. Kimble Frazer, MD, PhD, Alesia Trakhimets, William Heaton, Jared Bearrs, Steven Warner, PhD, David Bearrs, PhD, Sunil Sharma, MD

Blood (2011) 118 (21): 1519.

https://doi.org/10.1182/blood.V118.21.1519.1519

Published: 2011

Journal Articles

T-Cell Receptor Gene Deletions Are Associated with High Risk Features and Worse Outcome In Childhood Precursor B-Cell Acute Lymphoblastic Leukemia (ALL)

Jonathan Downie, BS, Phillip Barnette, MD, Vladimir Rodic, BS, J. Kimble Frazer, MD, PhD, Nikolaus Trede, MD, PhD, Meenakshi Devidas, PhD, Charles Mullighan, MBBS, MD, FRACP, FRCPA, MSc, Stephen Hunger, MD, Rodney R. Miles, MD, PhD, Joshua D. Schiffman, MD

Blood (2010) 116 (21): 275.

https://doi.org/10.1182/blood.V116.21.275.275

Published: 2010

Journal Articles

A Drug Screen in Zebrafish Identifies a New Therapeutic Agent Active in Acute Lymphoblastic Leukemia

Nikolaus Trede, MD, PhD, Suzanne Ridges, BS, Deepa Joshi, BS, Jon Beck, Hossein Soffla, Kaveri Balan, PhD, Betsy Manos, BS, Alexis Davis, Nathan Sweeney, BS, Nathan Meeker, MD, J. Kimble Frazer, MD, PhD, Archana Agarwal, MD, Radia Johnson, PhD, Irina Matei, PhD, Bertrand Montpellier, PhD, Cynthia Guidos, PhD, Matthew Sigman, PhD, David Jones, PhD

Blood (2010) 116 (21): 2129.

https://doi.org/10.1182/blood.V116.21.2129.2129

Published: 2010

Journal Articles

Cross-Species Comparison of Acquired Genetic Changes In T Cell Malignancy.

Lynnie A. Rudner, AB, Kim H. Brown, PhD, Kimberly P. Dobrinski, PhD, Diana F. Bradley, BS, Jonathan Downie, BS, Nathan D. Meeker, MD, Alexandra Smith, BA, Martha Iveth Garcia, Alejandro Gutierrez, MD, Charles Mullighan, MBBS, MD, FRACP, FRCPA, MSc, A. Thomas Look, MD, James R. Downing, MD, Joshua D. Schiffman, MD, Charles Lee, PhD, Nikolaus Trede, MD, PhD, J. Kimble Frazer, MD, PhD

Blood (2010) 116 (21): 1192.

https://doi.org/10.1182/blood.V116.21.1192.1192

Published: 2010

Journal Articles

VPREB1 Deletions Occur Independent of Lambda-Light Chain Rearrangement and Predict Worse Outcome In Pediatric Acute Lymphoblastic Leukemia (ALL)

Rodney R. Miles, MD, PhD, Jonathan Downie, BS, Mona S. Jahromi, BS, Deepa Joshi, BS, Vladimir Rodic, BS, Markus Muschen, MD, Jun J. Yang, PhD, William E. Evans, PharmD, Nathan Meeker, MD, Nikolaus Trede, MD, PhD, J. Kimble Frazer, MD, PhD, Phillip Barnette, MD, Joshua D. Schiffman, MD

Blood (2010) 116 (21): 273.

https://doi.org/10.1182/blood.V116.21.273.273

Published: 2010

Journal Articles

Three Heritable T Cell Malignancy Models Established Using a Forward Genetic Mutagenesis Screen in Zebrafish.

J. Kimble Frazer, MD, PhD, Nathan Meeker, MD, Diana F. Bradley, Lynnie Rudner, Sherrie L. Perkins, MD, PhD, Nikolaus Trede, MD, PhD

Blood (2008) 112 (11): 2052.

https://doi.org/10.1182/blood.V112.11.2052.2052

Published: 2008

NARROW

Exploring the Role of a Novel Tumor Suppressor - OSR2 in T-ALL

Deranged Transcription and Replication in MYC-Induced B and T Cell Leukemias

CHD1 - a Novel Epigenetic Regulator in Myeloid Malignancies with a Role in DNA Repair

Zebrafish screen identifies novel compound with selective toxicity against leukemia

Focal 22q11.22 Loss Combined with IKZF1 Alterations Predict Very Poor Outcome in Childhood Acute Lymphoblastic Leukemia

A Novel Dual AXL/Mertk and Aurora Kinase Inhibitor Active Against T Cell Acute Lymphoblastic Leukemia

T-Cell Receptor Gene Deletions Are Associated with High Risk Features and Worse Outcome In Childhood Precursor B-Cell Acute Lymphoblastic Leukemia (ALL)

A Drug Screen in Zebrafish Identifies a New Therapeutic Agent Active in Acute Lymphoblastic Leukemia

Cross-Species Comparison of Acquired Genetic Changes In T Cell Malignancy.

VPREB1 Deletions Occur Independent of Lambda-Light Chain Rearrangement and Predict Worse Outcome In Pediatric Acute Lymphoblastic Leukemia (ALL)

Three Heritable T Cell Malignancy Models Established Using a Forward Genetic Mutagenesis Screen in Zebrafish.

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American Society of Hematology

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American Society of Hematology

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