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Journal Articles

Safety and Efficacy of R-CEEP (Rituximab, Cyclophosphamide, Epirubicin, Etoposide, Prednisolone) in Elderly or Unfit Patients with Diffuse Large B-Cell Lymphoma (DLBCL): A Retrospective Single-Centre Experience

James Yeung, MBBS, Ashlea Campbell, BSc MBBS FRACP FRCPA, Christian E Bryant, MBBS PhDFRACP FRCPA, Liane Khoo, MBBS PhDFRACP FRCPA, Scott Dunkley, MBBS FRACP FRCPA, Harry J Iland, MBBS FRACP FRCPA MHGSA, Stephen R Larsen, MBBS PhDFRACP FRCPA, Susan Moreton, MBBS FRACP FRCPA, Douglas E Joshua, BSc(Hons) MBBS DPhil FRACP FRCPA, Vinay Vanguru, MBBS FRACP FRCPA, Derek A McCulloch, BSc MBBChir PhDFRACP FRCPA, Danny Hsu, MBBS FRACP FRCPA, John Gibson, MBBS PhDFRACP FRCPA, P. Joy Ho, MBBS DPhil FRACP FRCPA, Christina Brown, MBBS PhDFRACP FRCPA

Blood (2019) 134 (Supplement_1): 2911.

https://doi.org/10.1182/blood-2019-131589

Published: 2019

Journal Articles

Early Serum Free Light Chain (SFLC) Kinetics Is Highly Predictive of Renal Response in Carfilzomib/ Dexamethasone (Cfz/Dex) in Myeloma (MM) Patients with Renal Impairment (RI) — Interim Analysis of the Australian ALLG MM16 Trial

Phoebe Joy Ho, MBBS DPhil FRACP FRCPA, Andrew Spencer, MBBS, FRACP, FRCPA, DM, Peter Mollee, FRACP, FRCPA, MBBS, MMSc, Anoop K Enjeti, MBBS, FRCPA, MD MRCP, Noemi Horvath, MBBS FRACP FRCPA, Christian E Bryant, MBBS, PhD FRACP, FRCPA, Judith Trotman, Simon Gibbs, FRACP, FRCPA, MBBS, Douglas E Joshua, BSc(Hons) MBBS DPhil FRACP FRCPA

Blood (2018) 132 (Supplement 1): 3283.

https://doi.org/10.1182/blood-2018-99-110664

Published: 2018

Journal Articles

A Blood Dendritic Cell Vaccine for Acute Myeloid Leukemia Expands Anti-Tumour T Cell Responses at Remission

Derek NJ Hart, PhD FRCPA, FRACP, MB, Jennifer L Hsu, Christian E Bryant, Michael S Papadimitrious, Benjamin Kong, Robin E Gasiorowski, Daniel W Orellana, Helen McGuire, Barbara Fazekas de St Groth, Douglas E. Joshua, Phoebe Joy Ho, Stephen R Larsen, Harry J Iland, John Gibson, Georgina J Clark, Phillip D Fromm

Blood (2017) 130 (Supplement 1): 2648.

https://doi.org/10.1182/blood.V130.Suppl_1.2648.2648

Published: 2017

Journal Articles

A Blood Dendritic Cell Vaccine for Acute Myeloid Leukemia

Jennifer Hsu, PhD, Christian Bryant, Phillip Fromm, PhD, Michael Papadimitrious, Daniel Orellana, Hayley Suen, Shihong Yang, Claire Weatherburn, Robin Gasiorowski, Harry J Iland, MBBS FRACP FRCPA, Ross D Brown, Douglas E Joshua, Phoebe Joy Ho, MBBS, DPhil, John Gibson, Georgina Clark, Derek NJ Hart

Blood (2016) 128 (22): 5221.

https://doi.org/10.1182/blood.V128.22.5221.5221

Published: 2016

Journal Articles

Phospho-Flow Cytometry Quantitation of STAT Signalling Checkpoints in Malignant and Non-Malignant Cells Identifies Patients Suitable for pSTAT3 and 5 Targeted Inhibitors

Ross D Brown, P Joy Ho, Douglas E Joshua, Shihong Yang, Christian Bryant, Hayley Suen, Claire Weatherburn, Stephen Larsen, Derek NJ Hart, John Gibson

Blood (2015) 126 (23): 5356.

https://doi.org/10.1182/blood.V126.23.5356.5356

Published: 2015

Journal Articles

Protective Cytotoxic Clonal T-Cells in Myeloma Have the Characteristics of Telomere-Independent Senescence Rather Than an Exhausted or Anergic Phenotype: Implications for Immunotherapy

Hayley Suen, BSc (Hons), Douglas E Joshua, MBBS DPhil, Ross D Brown, PhD, Shihong Yang, MSc, Pasquale Mario Barbaro, MBBS, P Joy Ho, MBBS DPhil, John Gibson, MBBS PhD

Blood (2014) 124 (21): 3367.

https://doi.org/10.1182/blood.V124.21.3367.3367

Published: 2014

Journal Articles

Ten Year Survival in Patients with Myeloma Is Characterized by the Persistence of Immunological Control Which Is Detected by Immunological Biomarkers

Ross D Brown, PhD, Hayley Suen, BSc (Hons), Christian E Bryant, MBBS, Shihong Yang, MSc, James Favaloro, BSc, John Gibson, MBBS PhD, P Joy Ho, MBBS, DPhil, Phillip Fromm, PhD, Derek NJ Hart, MBCHB, DPhil, Douglas E Joshua, MBBS, DPhil

Blood (2012) 120 (21): 1818.

https://doi.org/10.1182/blood.V120.21.1818.1818

Published: 2012

Journal Articles

Lower Drug Exposure Is Related to Renal Function and Results in Inferior Survival: A Pharmacokinetic Study of High Dose Melphalan in Myeloma

Judith Trotman, MBChB, Peter J. Shaw, MBBS, MA, Douglas E Joshua, MBBS, DPhil, Yiu-Lam Kwan, MBBS, Campbell Tiley, MBBS, FRACP, FRCPA, Peter Presgrave, MBBS, PhD, Ian H. Kerridge, MBBS, MPhil, Christa Nath, BSc (Hons), PhD

Blood (2012) 120 (21): 1979.

https://doi.org/10.1182/blood.V120.21.1979.1979

Published: 2012

Journal Articles

Blockade of the Hedgehog Signaling Pathway by the Novel Agent NVP-LDE225 Induces Differentiation, Prevents De-Differentiation and Inhibits Proliferation of Multiple Myeloma Stem Cells in Vitro

Shihong Yang, MSc, Ross D Brown, PhD, Yen S Loh, PhD, Hayley Suen, BSc (Hons), James Favaloro, BSc, John Gibson, MBBS, PhD, Phoebe Joy Ho, MBBS, DPhil, Douglas E Joshua, MBBS, DPhil

Blood (2012) 120 (21): 3950.

https://doi.org/10.1182/blood.V120.21.3950.3950

Published: 2012

Journal Articles

Bortezomib-Based Induction Overcomes Effect of 1q Amplification On Response in Newly-Diagnosed Myeloma and Results in Similar 2 Year Event-Free Survival

Douglas E Joshua, MBBS, DPhil, Mark S Hertzberg, MD, PhD, Bradley Auguston, Andrew Spencer, MD, Noemi Horvath, MB, ChB, FRACP, FRCPA, John Bashford, MBBS, FRACP, FRCPA, Lynda J Campbell, Eleanor Ashurst, Jacquelyn Wade, Michael C. Copeman, DPhil, FRACP, Belinda E Butcher, BSc(Hons) MBiostat PhD, Miles Prince, MD, FRACP, FRCPA

Blood (2012) 120 (21): 4065.

https://doi.org/10.1182/blood.V120.21.4065.4065

Published: 2012

Journal Articles

Ten Year Survivors of Multiple Myeloma Demonstrate a Differential Expression of Immunological Biomarkers Including a High Incidence of Cytotoxic T-Cell Clones Which Have Not Acquired Myeloma-Associated Anergy,

Christian E Bryant, MBBS, Ross D Brown, DPhil, Shihong Yang, BSc, Hayley Suen, BSc, Esther Aklilu, BSc, James Favaloro, BSc, Derek NJ Hart, MBCHB, DPhil, Phillip Fromm, DPhil, Narelle Woodland, MSc, Najah Nassif, DPhil, Harry Iland, MBBS FRACP FRCPA MHGSA, John Gibson, MBBS FRACP FRCPA DPhil, P Joy Ho, MBBS, DPhil, Douglas E Joshua, MBBS, DPhil

Blood (2011) 118 (21): 3924.

https://doi.org/10.1182/blood.V118.21.3924.3924

Published: 2011

Journal Articles

Safety and Efficacy of CEEP (Cyclophosphamide, Epirubicin, Etoposide, Prednisolone) with or without Rituximab in Elderly Patients (>70) with Diffuse Large B-Cell Lymphoma (DLBL): A Retrospective Single Center Experience

Danny Hsu, MBBS FRACP FRCPA, Ibrahim Tohidi-Esfahani, MBBS, Christina Brown, MBBS PhD FRACP FRCPA, Scott Dunkley, MBBS FRACP FRCPA, Stephen Robert Larsen, MBBS FRACP FRCPA PhD, Phoebe Joy Ho, MBBS FRCPA FRACP DPhil, Harry Iland, MBBS FRACP FRCPA MHGSA, John Gibson, MBBS FRACP FRCPA DPhil, Douglas E. Joshua, MBBS DPhil FRACP FRCPA AM

Blood (2011) 118 (21): 4957.

https://doi.org/10.1182/blood.V118.21.4957.4957

Published: 2011

Journal Articles

HLA-G and CD86 Expression on Malignant Plasma Cells Convey a Poor Prognosis and Immunoregulate T Cells In Patients with Myeloma

Ross D. Brown, PhD, Karieshma Kabani, Shihong Yang, Esther Aklilu, Phoebe Joy Ho, MBBS, John Gibson, MBBS, Douglas E. Joshua, MBBS, DPhil

Blood (2010) 116 (21): 983.

https://doi.org/10.1182/blood.V116.21.983.983

Published: 2010

Journal Articles

Clonal expansions of cytotoxic T cells exist in the blood of patients with Waldenström macroglobulinemia but exhibit anergic properties and are eliminated by nucleoside analogue therapy

Jia Li, Daniel M.-Y. Sze, Ross D. Brown, Mark J. Cowley, Warren Kaplan, Sui-Lin Mo, Shihong Yang, Esther Aklilu, Karieshma Kabani, Yen S. Loh, Tetsuo Yamagishi, Yuling Chen, P. Joy Ho, Douglas E. Joshua

Blood (2010) 115 (17): 3580–3588.

https://doi.org/10.1182/blood-2009-10-246991

Published: 2010

Includes: Supplemental data

Journal Articles

Trogocytosis in Multiple Myeloma.

Ross D. Brown, PhD, MBA, Karieshma Kabani, BSc, Shihong Yang, MSc, Aklilu Esther, BSc, Phoebe Joy Ho, MBBS, DPhil, John Gibson, MBBS, PhD, Douglas E. Joshua, MBBS, DPhil

Blood (2008) 112 (11): 1681.

https://doi.org/10.1182/blood.V112.11.1681.1681

Published: 2008

Journal Articles

XBP-1 Levels Predict Sensitivity of Myelomas to Proteasome Inhibitor Bortezomib.

Silvia C. Ling, MBBS, FRACP, FRCPA, Edwin Lau, BSc, Lye L. Ho, MBBS, FRCPA, FRACP, Joy Ho, MBBS, FRCPA, FRACP, Douglas E. Joshua, MBBS, DPHil(Oxon)FR, John Allen, PhD

Blood (2007) 110 (11): 1473.

https://doi.org/10.1182/blood.V110.11.1473.1473

Published: 2007

Journal Articles

C-MYC Correlates with Expression of Multidrug Transporters ABCC1 and ABCC4.

Lye Lin Ho, MBBS, FRACP, FRCPA, Li Chong, PhD, Silvia Ling, MBBS, FRACP, FRCPA, Diana Lau, MSc, Edwin Lau, BSc, Harry Iland, MBBS, FRACP, FRCPA, Douglas E. Joshua, MBBS, DPhil, FRACP, John Allen, PhD

Blood (2007) 110 (11): 3467.

https://doi.org/10.1182/blood.V110.11.3467.3467

Published: 2007

Journal Articles

Optimizing Mobilization, Augmentation, and Gene Transfer of Multipotent Mesenchymal Stromal Cells (MSCs).

Stephen R. Larsen, MBBS, Keefe Chng, BVSc, Shangzhen Zhou, John Wright, PhD, Margaret Armstrong, Sally Thompson, BVSc, Annemarie Hennessy, MBBS PhD, Rosetta Martiniello-Wilks, BSc PhD, John Gibson, MBBS PhD, Douglas E. Joshua, MBBS PhD, John E.J. Rasko, MBBS PhD

Blood (2006) 108 (11): 2555.

https://doi.org/10.1182/blood.V108.11.2555.2555

Published: 2006

Journal Articles

Identification and Characterization of Cancer Stem Cells in Multiple Myeloma.

Daniel Sze, PhD, Yen S. Loh, BSc, Suilin Mo, MSc, Warren Kaplan, PhD, Ross D. Brown, PhD, Phoebe Joy Ho, MD, John Gibson, MD, Douglas E. Joshua, MD

Blood (2006) 108 (11): 512.

https://doi.org/10.1182/blood.V108.11.512.512

Published: 2006

Journal Articles

Gene Expression Profiling of the Clinical Significant CD57 + CD8 + Cytotoxic T Cell Expansions in Patients with Waldenstrom’s Macroglobulinemia.

Daniel Sze, PhD, Tetsuo Yamagishi, BSc, Warren Kaplan, PhD, Ross D. Brown, PhD, Phoebe Joy Ho, MD, John Gibson, MD, Douglas E. Joshua, MD

Blood (2006) 108 (11): 3395.

https://doi.org/10.1182/blood.V108.11.3395.3395

Published: 2006

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Safety and Efficacy of R-CEEP (Rituximab, Cyclophosphamide, Epirubicin, Etoposide, Prednisolone) in Elderly or Unfit Patients with Diffuse Large B-Cell Lymphoma (DLBCL): A Retrospective Single-Centre Experience

Early Serum Free Light Chain (SFLC) Kinetics Is Highly Predictive of Renal Response in Carfilzomib/ Dexamethasone (Cfz/Dex) in Myeloma (MM) Patients with Renal Impairment (RI) — Interim Analysis of the Australian ALLG MM16 Trial

A Blood Dendritic Cell Vaccine for Acute Myeloid Leukemia Expands Anti-Tumour T Cell Responses at Remission

A Blood Dendritic Cell Vaccine for Acute Myeloid Leukemia

Phospho-Flow Cytometry Quantitation of STAT Signalling Checkpoints in Malignant and Non-Malignant Cells Identifies Patients Suitable for pSTAT3 and 5 Targeted Inhibitors

Protective Cytotoxic Clonal T-Cells in Myeloma Have the Characteristics of Telomere-Independent Senescence Rather Than an Exhausted or Anergic Phenotype: Implications for Immunotherapy

Ten Year Survival in Patients with Myeloma Is Characterized by the Persistence of Immunological Control Which Is Detected by Immunological Biomarkers

Lower Drug Exposure Is Related to Renal Function and Results in Inferior Survival: A Pharmacokinetic Study of High Dose Melphalan in Myeloma

Blockade of the Hedgehog Signaling Pathway by the Novel Agent NVP-LDE225 Induces Differentiation, Prevents De-Differentiation and Inhibits Proliferation of Multiple Myeloma Stem Cells in Vitro

Bortezomib-Based Induction Overcomes Effect of 1q Amplification On Response in Newly-Diagnosed Myeloma and Results in Similar 2 Year Event-Free Survival

Ten Year Survivors of Multiple Myeloma Demonstrate a Differential Expression of Immunological Biomarkers Including a High Incidence of Cytotoxic T-Cell Clones Which Have Not Acquired Myeloma-Associated Anergy,

Safety and Efficacy of CEEP (Cyclophosphamide, Epirubicin, Etoposide, Prednisolone) with or without Rituximab in Elderly Patients (>70) with Diffuse Large B-Cell Lymphoma (DLBL): A Retrospective Single Center Experience

HLA-G and CD86 Expression on Malignant Plasma Cells Convey a Poor Prognosis and Immunoregulate T Cells In Patients with Myeloma

Clonal expansions of cytotoxic T cells exist in the blood of patients with Waldenström macroglobulinemia but exhibit anergic properties and are eliminated by nucleoside analogue therapy

Trogocytosis in Multiple Myeloma.

XBP-1 Levels Predict Sensitivity of Myelomas to Proteasome Inhibitor Bortezomib.

C-MYC Correlates with Expression of Multidrug Transporters ABCC1 and ABCC4.

Optimizing Mobilization, Augmentation, and Gene Transfer of Multipotent Mesenchymal Stromal Cells (MSCs).

Identification and Characterization of Cancer Stem Cells in Multiple Myeloma.

Gene Expression Profiling of the Clinical Significant CD57 + CD8 + Cytotoxic T Cell Expansions in Patients with Waldenstrom’s Macroglobulinemia.

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