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Journal Articles

Integration of Deep Multi-Omics Profiling Veals New Insights into the Biology of Poor-Risk Acute Myeloid Leukemia

Blood (2020) 136 (Supplement 1): 39–40.

https://doi.org/10.1182/blood-2020-141345

Published: 2020

Journal Articles

DCE-MRI for Detection of Acute Myeloid Leukemia Derived Bone Marrow Vascular Dysfunction

Ana Da Silva Gomes, PhD, Bernard Siow, PhD, Diana Passaro, PhD, Dominique Bonnet, PhD

Blood (2020) 136 (Supplement 1): 29.

https://doi.org/10.1182/blood-2020-141256

Published: 2020

Journal Articles

JMML Fetal Identity Results Either from Retention of a Physiologic Signature or Aberrant Activation of Master Oncofetal Regulators

Marion Strullu, MD, Aurélie Caye-Eude, PharmD, PhD, Loïc Maillard, PhD, Chloé Arfeuille, MD, Elodie Lainey, PharmD, PhD, Florian Piques, MD, Odile Fenneteau, PharmD, Bruno Cassinat, PharmD, PhD, Fabien Guimiot, PhD, Jean-Hugues Dalle, MD PhD, André Baruchel, Christine Chomienne, MD PhD, Dominique Bonnet, PhD, Michele Souyri, PhD, Hélène Cavé, PharmD, PhD

Blood (2020) 136 (Supplement 1): 4–5.

https://doi.org/10.1182/blood-2020-136367

Published: 2020

Journal Articles

Activation of the Receptor Tyrosine Kinase (RET) By GDNF/GFRα1 Improves Cord Blood-Derived HSC in Vitro expansion and In Vivo engraftment

William Grey, PhD MSc, Rakhee Chauhan, PhD, Manuel Garcia-Albornoz, Hector Huerga Encabo, Neil McDonald, PhD, Dominique Bonnet, PhD

Blood (2019) 134 (Supplement_1): 1924.

https://doi.org/10.1182/blood-2019-121331

Published: 2019

Journal Articles

Combination Therapy Targeting CKS1-Dependent Protein Degradation Reduces AML Burden Whilst Protecting Normal Haematopoietic Stem Cellsfrom Cytarabine Toxicity

William Grey, PhD MSc, Pedro Casado-Izquierdo, Pedro Cutillas, PhD, Dominique Bonnet, PhD

Blood (2019) 134 (Supplement_1): 2535.

https://doi.org/10.1182/blood-2019-121667

Published: 2019

Journal Articles

Adipocyte Induced Antagonism of ALL Growth Highlights a Novel Inhibitory Niche and Potential Therapeutic Opportunity

Nicholas Warrick, BSc, Farideh Miraki-Moud, PhD, A Aicher, Linda Ariza McNaughton, Pedro Casado-Izquierdo, Ai Nagano, PhD, Rebecca Carroll, Dominique Bonnet, PhD, John G. Gribben, MDDSc FMedSci, Bela Patel, MD

Blood (2017) 130 (Supplement 1): 371.

https://doi.org/10.1182/blood.V130.Suppl_1.371.371

Published: 2017

Journal Articles

Functional Characteristics of FAS-L Resistant and IL-2 Deprived Regulatory T Cells (Treg A) in Idiopathic Aplastic Anaemia

Benedetta Costantini, MD, Syed A Mian, PhD, Shok Ping Lim, PhD, Frederic Toulza, PhD, Stephen Orr, PhD, Pilar Perez-Abellan, MSc, Ander Abarrategi, PhD, Farzin Farzaneh, PhD, Dominique Bonnet, PhD, Judith Marsh, MD, Shahram Kordasti, MD PhD, Ghulam Mufti, DM, FRCP, FRCPath

Blood (2017) 130 (Supplement 1): 2450.

https://doi.org/10.1182/blood.V130.Suppl_1.2450.2450

Published: 2017

Journal Articles

Bone Marrow Stem Cells from Patients with Myelodysplastic Syndrome (MDS) Engraft and Migrate in-between the Humanized Niches in Immuno-Compromised Mouse Models

Syed A Mian, PhD, Kevin Rouault-Pierre, PhD, Alexander E Smith, PhD, Ander Abarrategi, PhD, Thomas Coats, MD, Donal McLornan, Ghulam Mufti, DM, FRCP, FRCPath, Dominique Bonnet, PhD

Blood (2017) 130 (Supplement 1): 49.

https://doi.org/10.1182/blood.V130.Suppl_1.49.49

Published: 2017

Journal Articles

Intravital Microscopy Reveals Fundamental Differences in the Interaction of Stem Cells and T Acute Lymphoblastic Leukaemia with the Bone Marrow Microenvironment

Blood (2016) 128 (22): 5199.

https://doi.org/10.1182/blood.V128.22.5199.5199

Published: 2016

Journal Articles

Increased Vascular Permeability in the Bone Marrow Microenvironment Contributes to Acute Myeloid Leukemia Progression and Drug Response

Diana Passaro, PhD, Alessandro Di Tullio, PhD, Ander Abarrategi, PhD, Kevin Rouault-Pierre, PhD, Katie Foster, PhD, Linda Ariza McNaughton, PhD, Francois Lassailly, PhD, Dominique Bonnet, PhD

Blood (2016) 128 (22): 2662.

https://doi.org/10.1182/blood.V128.22.2662.2662

Published: 2016

Journal Articles

Impairment of AML Engraftment to the Bone Marrow Niche Following Inhibition of TGF-Beta Signaling

Ashley Hamilton, PhD, Katie Foster, PhD, Dominique Bonnet, PhD

Blood (2014) 124 (21): 4372.

https://doi.org/10.1182/blood.V124.21.4372.4372

Published: 2014

Journal Articles

A 16-Gene Signature Associated with High Levels of Wilms Tumor-1 ( WT1 ) Expression Is an Adverse Prognostic Factor in Acute Myeloid Leukemia

Ahmadreza Niavarani, MD PhD, Tobias Herold, MD, Yasmin Reyal, MD PhD, Erin Currie, MSc, Stuart Horswell, PhD, Arash Jalali, PhD, Maria Cristina Sauerland, MSc, Thomas Buchner, MD, Wolfgang Hiddemann, MD, Stefan K Bohlander, PhD, Reza Malekzadeh, MD AGAF, Peter J.M. Valk, PhD, Dominique Bonnet, PhD

Blood (2014) 124 (21): 1021.

https://doi.org/10.1182/blood.V124.21.1021.1021

Published: 2014

Journal Articles

Arginine Deprivation With Pegylated Arginine Deiminase Induces Death Of Acute Myeloid Leukaemia Cells In Vivo

Farideh Miraki-Moud, PhD, Linda Ariza-McNaughton, MSc, Essam A Ghazaly, MD, Katharine A Hodby, Phuong Luong, Andrew Clear, PhD, Fareeda Sohrabi, John Bomalaski, John Gribben, MD, DSc, Dominique Bonnet, PhD, Peter Szlosarek, David C Taussig, PhD, MRCP, FRCPath

Blood (2013) 122 (21): 1458.

https://doi.org/10.1182/blood.V122.21.1458.1458

Published: 2013

Journal Articles

Perturbed Hematopoiesis In Mice Lacking ATMIN (an ATM co-Factor)

Fernando Anjos-Afonso, MSc. PhD., Joanna Loizou, PhD, Dominique Bonnet, PhD, Axel Behrens, PhD

Blood (2013) 122 (21): 2412.

https://doi.org/10.1182/blood.V122.21.2412.2412

Published: 2013

Journal Articles

SF3B1 Mutant Clones From Patients With Refractory Anaemia With Ringed Sideroblasts (RARS) Originate From The Early Haematopoietic Stem Cells and Maintain Their Engraftment Potential

Syed A Mian, Kevin Rouault-Pierre, PhD, Alexander E Smith, PhD, Thomas Seidl, Austin G Kulasekararaj, MBBS, MD, MRCP, FRCP, Azim M Mohamedali, PhD, Sneha Shinde, Msc., Dominique Bonnet, PhD, Ghulam J. Mufti, MD, PhD

Blood (2013) 122 (21): 262.

https://doi.org/10.1182/blood.V122.21.262.262

Published: 2013

Journal Articles

Targeting of Acute Myeloid Leukemia by Cytokine-Induced Killer Cells Redirected with a Novel CD123-Specific Chimeric Antigen Receptor.

Sarah Tettamanti, PhD student, Virna Marin, PhD, Irene Pizzitola, PhD student, Chiara Francesca Magnani, PhD, Greta Maria Paola Giordano Attianese, PhD, Elisabetta Cribioli, Angel Lopez, PhD, Andrea Biondi, MD, Dominique Bonnet, PhD, Ettore Biagi, MD, PhD

Blood (2012) 120 (21): 3010.

https://doi.org/10.1182/blood.V120.21.3010.3010

Published: 2012

Journal Articles

Human Primary Mantle Cell Lymphoma Can Be Established in NOD/SCID/IL2Rγ-Null Mice

Sunil Iyengar, MD, Linda Ariza-McNaughton, MSc, Andrew James Clear, BSc, Amy Roe, Debra Lillington, PhD, David C Taussig, PhD, MRCP, FRCPath, John G Gribben, Simon Joel, Dominique Bonnet, PhD

Blood (2012) 120 (21): 1565.

https://doi.org/10.1182/blood.V120.21.1565.1565

Published: 2012

Journal Articles

Chimeric Antigen Receptor for Specific Targeting of Acute Myeloid Leukemia

Irene Pizzitola, Fernando Anjos-Afonso, Kevin Rouault-Pierre, Francois Lassailly, Sarah Tettamanti, PhD student, Andrea Biondi, Ettore Biagi, MD, PhD, Dominique Bonnet, PhD

Blood (2012) 120 (21): 4225.

https://doi.org/10.1182/blood.V120.21.4225.4225

Published: 2012

Journal Articles

Non-Invasive Multimodal/Multi-Scale Imaging of Bone Marrow Microenvironment Reveals Structural and Functional Heterogeneity in Different Bone Marrow Compartments: Functional Implications On Mouse and Human Hematopoietic Stem Cell Niches in Health and Disease

Francois Lassailly, MSc, PhD, Katie Foster, PhD, Lourdes Lopez-Onieva, PhD, Erin Currie, Dominique Bonnet, PhD

Blood (2012) 120 (21): 25.

https://doi.org/10.1182/blood.V120.21.25.25

Published: 2012

Journal Articles

CD26 Inhibition Can Aid the Homing of Cytokine Activated Mobilized Peripheral Blood (MPB )CD34 + Cells to the Bone Marrow (BM) but a Ligand Dependent Attachment Defect Prevents Their Long Term Retention and Subsequent Engraftment

Konstantina Kallinikou, Fernando Anjos-Afonso, Michael P Blundell, Stuart J Ings, Deepika Kassen, PhD, Adrian J Thrasher, MD, PhD, David C Linch, MD FMedSci, Dominique Bonnet, PhD, Kwee Yong, PhD

Blood (2011) 118 (21): 141.

https://doi.org/10.1182/blood.V118.21.141.141

Published: 2011

NARROW

Integration of Deep Multi-Omics Profiling Veals New Insights into the Biology of Poor-Risk Acute Myeloid Leukemia

DCE-MRI for Detection of Acute Myeloid Leukemia Derived Bone Marrow Vascular Dysfunction

JMML Fetal Identity Results Either from Retention of a Physiologic Signature or Aberrant Activation of Master Oncofetal Regulators

Activation of the Receptor Tyrosine Kinase (RET) By GDNF/GFRα1 Improves Cord Blood-Derived HSC in Vitro expansion and In Vivo engraftment

Combination Therapy Targeting CKS1-Dependent Protein Degradation Reduces AML Burden Whilst Protecting Normal Haematopoietic Stem Cellsfrom Cytarabine Toxicity

Adipocyte Induced Antagonism of ALL Growth Highlights a Novel Inhibitory Niche and Potential Therapeutic Opportunity

Functional Characteristics of FAS-L Resistant and IL-2 Deprived Regulatory T Cells (Treg A) in Idiopathic Aplastic Anaemia

Bone Marrow Stem Cells from Patients with Myelodysplastic Syndrome (MDS) Engraft and Migrate in-between the Humanized Niches in Immuno-Compromised Mouse Models

Intravital Microscopy Reveals Fundamental Differences in the Interaction of Stem Cells and T Acute Lymphoblastic Leukaemia with the Bone Marrow Microenvironment

Increased Vascular Permeability in the Bone Marrow Microenvironment Contributes to Acute Myeloid Leukemia Progression and Drug Response

Impairment of AML Engraftment to the Bone Marrow Niche Following Inhibition of TGF-Beta Signaling

A 16-Gene Signature Associated with High Levels of Wilms Tumor-1 ( WT1 ) Expression Is an Adverse Prognostic Factor in Acute Myeloid Leukemia

Arginine Deprivation With Pegylated Arginine Deiminase Induces Death Of Acute Myeloid Leukaemia Cells In Vivo

Perturbed Hematopoiesis In Mice Lacking ATMIN (an ATM co-Factor)

SF3B1 Mutant Clones From Patients With Refractory Anaemia With Ringed Sideroblasts (RARS) Originate From The Early Haematopoietic Stem Cells and Maintain Their Engraftment Potential

Targeting of Acute Myeloid Leukemia by Cytokine-Induced Killer Cells Redirected with a Novel CD123-Specific Chimeric Antigen Receptor.

Human Primary Mantle Cell Lymphoma Can Be Established in NOD/SCID/IL2Rγ-Null Mice

Chimeric Antigen Receptor for Specific Targeting of Acute Myeloid Leukemia

Non-Invasive Multimodal/Multi-Scale Imaging of Bone Marrow Microenvironment Reveals Structural and Functional Heterogeneity in Different Bone Marrow Compartments: Functional Implications On Mouse and Human Hematopoietic Stem Cell Niches in Health and Disease

CD26 Inhibition Can Aid the Homing of Cytokine Activated Mobilized Peripheral Blood (MPB )CD34 + Cells to the Bone Marrow (BM) but a Ligand Dependent Attachment Defect Prevents Their Long Term Retention and Subsequent Engraftment

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American Society of Hematology

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ASH Publications

American Society of Hematology

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