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David W. Hedley
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Journal Articles

Cyproheptadine displays preclinical activity in myeloma and leukemia

Xinliang Mao, Sheng-ben Liang, Rose Hurren, Marcela Gronda, Sue Chow, G. Wei Xu, Xiaoming Wang, Reza Beheshti Zavareh, Nazir Jamal, Hans Messner, David W. Hedley, Alessandro Datti, Jeff L. Wrana, Yuanxiao Zhu, Chang-xin Shi, Kyle Lee, Rodger Tiedemann, Suzanne Trudel, A. Keith Stewart, Aaron D. Schimmer
Journal: Blood
Blood (2008) 112 (3): 760–769.
https://doi.org/10.1182/blood-2008-02-142687
Published: 2008
Includes: Supplemental data
Journal Articles

A High Throughput Screen Identified Cyproheptadine That Decreases D-Type Cyclins, Arrests Cells in the G1 Phase, and Induces Apoptosis in Multiple Myeloma and Leukemia Cells.

Xinliang Mao, PhD, A. Keith Stewart, MD, Rose Hurren, BSc, Marcela Gronda, MSc, Kyle Lee, BSc, Sue Chow, BSc, Shengben Liang, PhD, Suzanne Trudel, MD, David W. Hedley, MD, PhD, Aaron D. Schimmer, Md, PhD
Journal: Blood
Blood (2007) 110 (11): 1507.
https://doi.org/10.1182/blood.V110.11.1507.1507
Published: 2007
Journal Articles

The death-promoting activity of p53 can be inhibited by distinct signaling pathways

Yunping Lin, Lauren Brown, David W. Hedley, Dwayne L. Barber, Samuel Benchimol
Journal: Blood
Blood (2002) 100 (12): 3990–4000.
https://doi.org/10.1182/blood-2002-02-0504
Published: 2002
Journal Articles

Receptor- and mitochondrial-mediated apoptosis in acute leukemia: a translational view

Aaron D. Schimmer, David W. Hedley, Linda Z. Penn, Mark D. Minden
Journal: Blood
Blood (2001) 98 (13): 3541–3553.
https://doi.org/10.1182/blood.V98.13.3541
Published: 2001
Journal Articles

Increased Sensitivity of Acute Myeloid Leukemias to Lovastatin-Induced Apoptosis: A Potential Therapeutic Approach

Jim Dimitroulakos, Dana Nohynek, Karen L. Backway, David W. Hedley, Herman Yeger, Melvin H. Freedman, Mark D. Minden, Linda Z. Penn
Journal: Blood
Blood (1999) 93 (4): 1308–1318.
https://doi.org/10.1182/blood.V93.4.1308
Published: 1999