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Daphné Dupéré-Richer
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Journal Articles

NSD2 drives t(4;14) myeloma cell dependence on adenylate kinase 2 by diverting one-carbon metabolism to the epigenome

Amin Sobh, Elena Encinas, Alisha M Patel, Greeshma Surapaneni, Emilie Bonilla, Charlotte Leonie Kaestner, Janai Poullard, PA-S, Monica Clerio, Karthik Vasan, Tzipporah Freeman, Dongwen Lv, Daphné Dupéré-Richer, Alberto Riva, Benjamin G Barwick, Daohong Zhou, Lawrence H Boise, Constantine S. Mitsiades, Baek Kim, Richard L Bennett, Navdeep S Chandel, Jonathan D Licht
Journal: Blood
Blood blood.2023022859.
https://doi.org/10.1182/blood.2023022859
Published: 2024
Includes: Supplemental data
Journal Articles

Discovery and Development of CD70 As a Cellular Therapy Target in High Risk Multiple Myeloma

Corynn Kasap, Adila Izgutdina, Bonell Patino Escobar, Yu-Hsiu Tony Lin, Huimin Geng, Gianina Wicaksono, Daphne Dupere-Richer, Emilio Ramos, Abhilash Barpanda, Anjanaa Vijayanarayanan, Fernando Salangsang, Paul Phojanakong, Juan Antonio Camara Serrano, Veronica Steri, William Karlon, Mala Shanmugam, Lawrence H. Boise, Benjamin G. Barwick, Jonathan D. Licht, Arun P Wiita
Journal: Blood
Blood (2023) 142 (Supplement 1): 465.
https://doi.org/10.1182/blood-2023-182578
Published: 2023
Journal Articles

Activating NSD2 Mutations Drive Oncogenic Reprogramming By Disturbing Epigenetic Landscape in Mantle Cell Lymphoma

Jianping Li, Marta Kulis, Alberto Riva, Heidi Casellas Román, Daphne Dupere-Richer, Monica Clerio, Melanie L. Trejo, Michael Menes, Anthony Joseph Lamberto, Amin Sobh, Charlotte Leonie Kaestner, Richard Lynn Bennett, Iñaki I. Martin Subero, Jonathan D. Licht
Journal: Blood
Blood (2023) 142 (Supplement 1): 2771.
https://doi.org/10.1182/blood-2023-189748
Published: 2023
Journal Articles

Dysregulation of Epigenetic Landscape Uncovered the Mechanisms Underlying the Relapse of Pediatric Acute Lymphoblastic Leukemia with NSD2 Mutation

Jianping Li, Priscillia Lhoumaud, Alberto Riva, Crissandra Piper, Daphne Dupere-Richer, Heidi Casellas Roman, Amin Sobh, Charlotte L Kaestner, Alok Swaroop, Marta Kulis, Richard Lynn Bennett, Jane Skok, Jonathan D. Licht
Journal: Blood
Blood (2021) 138 (Supplement 1): 3297.
https://doi.org/10.1182/blood-2021-149985
Published: 2021
Journal Articles

KDM6A Controls Genes Modulating Immune Surveillance in Multiple Myeloma

Daphne Dupere-Richer, PhD, Sayantan Maji, PhD, Alberto Riva, PhD, Gabrielle Quickstad, Marta Kulis, Darby Monagle, José I. Martín-Subero, PhD, Richard Lynn Bennett, PhD, Jonathan D. Licht, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 14.
https://doi.org/10.1182/blood-2020-141285
Published: 2020
Journal Articles

NSD2-E1099K Mutation Leads to Glucocorticoid-Resistant B Cell Lymphocytic Leukemia in Mice

Jianping Li, MD, Crissandra Piper, LATG, Daphne Dupere-Richer, PhD, Heidi Casellas Roman, MS, Alok Swaroop, PhD, Catalina Troche, PhD, Jon Oyer, PhD, Christine Will, MS, Alberto Riva, PhD, Richard Lynn Bennett, PhD, Jonathan D. Licht, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 3–4.
https://doi.org/10.1182/blood-2020-141295
Published: 2020
Journal Articles

DNMT3A with Leukemia-Associated Mutations Directs Sensitivity to DNA Damage at Replication Forks

Kartika Venugopal, MS, Daniil E Shabashvili, PhD, Jianping Li, MD, Luisa M Posada, Richard Lynn Bennett, PhD, Yang Feng, MS, Daphne Dupere Richer, PhD, Alberto Riva, PhD, Santhi Pondugula, PhD, Jonathan E. Bird, PhD, Jonathan D. Licht, MD, Olga A Guryanova, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 535.
https://doi.org/10.1182/blood-2019-128213
Published: 2019
Journal Articles

A Gain of Function Mutation in the NSD2 Histone Methyltransferase Drives Glucocorticoid Resistance Via Blocking Receptor Auto-Induction and BIM/Bmf Expression in ALL

Jianping Li, MD, Catalina Troche, PhD, Julia Hlavka Zhang, BS, Jonathan Shrimp, PhD, Jacob S. Roth, PhD, Duohui Jing, PhD, Alok Swaroop, PhD, Marta Kulis, Jon Oyer, PhD, Christine Will, MS, Daphne Dupere-Richer, PhD, Alberto Riva, PhD, Crissandra Pipe, LATG, Amin Sobn, PhD, Sharon Norton, MS, Richard Lynn Bennett, PhD, Min Shen, PhD, Matthew D. Hall, PhD, Richard B. Lock, PhD, Jonathan D. Licht, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3758.
https://doi.org/10.1182/blood-2019-126910
Published: 2019
Journal Articles

A Gain of Function Mutation in the NSD2 Histone Methyltransferase Drives Glucocorticoid Resistance of Acute Lymphoblastic Leukemia

Jianping Li, MD, Catalina Troche, PhD, Alok Swaroop, PhD, Marta Kulis, PhD, Jon Oyer, PhD, Christine Will, MS, Daphne Dupere-Richer, PhD, Alberto Riva, PhD, Crissandra Pipe, LATG, Sharon Norton, MS, Richard Lynn Bennett, PhD, Jonathan D. Licht, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 653.
https://doi.org/10.1182/blood-2018-99-116309
Published: 2018
Journal Articles

Cells with DNMT3A Mutations Are More Sensitive to Cytarabine-Induced DNA Damage

Kartika Venugopal, MS, Jianping Li, MD, Daniil E Shabashvili, PhD, Luisa M Posada, Yang Feng, MS, Daphne Dupere-Richer, PhD, Aditya Bele, PhD, Jonathan D. Licht, MD, Olga A Guryanova, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2643.
https://doi.org/10.1182/blood-2018-99-118708
Published: 2018
Journal Articles

Loss of KDM6A/UTX Accelerate the Development of Multiple Myeloma

Daphne Dupere-Richer, PhD, Jianping Li, MD, Sayantan Maji, PhD, Crissandra Pipe, LATG, Sharon Norton, MS, Teresa Ezponda, PhD, Richard Lynn Bennett, PhD, Jonathan D. Licht, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1004.
https://doi.org/10.1182/blood-2018-99-113835
Published: 2018
Journal Articles

Functional Genomic Landscape of Epigenetic Dependencies in Myeloma

Ricardo De Matos Simoes, PhD, Geoffrey Matthews, PhD, Daphne Dupere Richer, PhD, Ryosuke Shirasaki, MD, Michal Sheffer, PhD, Olga Dashevsky, PhD, Sara Gandolfi, MD, Eugen Dhimolea, PhD, Brian Glassner, PhD, Richard WJ Groen, PhD, Franciska Vazquez, PhD, Joshua Dempster, PhD, Aviad Tsherniak, PhD, William C. Hahn, MD PhD, Aedin Culhane, PhD, Jonathan D. Licht, MD, Constantine S. Mitsiades, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1209.
https://doi.org/10.1182/blood.V130.Suppl_1.1209.1209
Published: 2017
Journal Articles

Resistance To Vorinostat In Hematological Malignancies May Involve Cytoprotective UPR and Correlates With Increased Sensitivity To Bortezomib-Induced Cell Death

Daphné Dupéré-Richer, Ph.D candidate, Mena Kinal, M.Sc., Filippa Pettersson, Ph.D, Wilson H. Miller, Jr., MD, PhD
Journal: Blood
Blood (2013) 122 (21): 5137.
https://doi.org/10.1182/blood.V122.21.5137.5137
Published: 2013