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Christine J Harrison, PhD FRCPath
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Journal Articles

Outcome of (Novel) Subgroups in 1257 Pediatric Patients with KMT2A-Rearranged Acute Myeloid Leukemia (AML) and the Significance of Minimal Residual Disease (MRD) Status: A Retrospective Study By the I-BFM-SG

Romy E. Van Weelderen, Kim Klein, MD, Bianca F. Goemans, MD PhD, Christian M. Zwaan, MD PhD, Hester A. De Groot-Kruseman, PhD, Jonas Abrahamsson, MD PhD, Nira Arad-Cohen, MD PhD, Emmanuelle Bart-Delabesse, PharmD, PhD, Barbara Buldini, MD PhD, Barbara De Moerloose, MD PhD, Michael Dworzak, MD PhD, Sarah Elitzur, MD, JosĂ© M. FernĂ¡ndez Navarro, MD, Robert B. Gerbing, MA, Erin Guest, MD, Shau-Yin Ha, MD PhD, Christine J. Harrison, PhD FRCPath, Henrik Hasle, PhD, Kathy Jackson, MD PhD, Charikleia Kelaidi, MD, HĂ©lène Lapillonne, MD PhD, Guy Leverger, MD PhD, Franco Locatelli, MD PhD, Takako Miyamura, MD PhD, Sophia Polychronopoulou, MD PhD, Mareike Rasche, MD, Jeffrey E. Rubnitz, MD, Jan Stary, MD PhD, Daisuke Tomizawa, MD PhD, Femke Verwer, Gertjan J.L. Kaspers, Prof. MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 26–27.
https://doi.org/10.1182/blood-2020-136064
Published: 2020
Journal Articles

NUTM1 -Rearranged Infant and Pediatric B Cell Precursor Acute Lymphoblastic Leukemia: A Good Prognostic Subtype Identified in a Collaborative International Study

Judith M. Boer, PhD, Maria Grazia Valsecchi, PhD, Femke M. Hormann, MSc, Zeljko Antic, MD, Marketa Zaliova, MD PhD, Claire Schwab, PhD, Giovanni Cazzaniga, PhD, Chloé Arfeuille, MD, Hélène Cavé, PharmD, PhD, Andishe Attarbaschi, MD, Sabine Strehl, PhD, Gabriele Escherich, MD, Toshihiko Imamura, MD PhD, Kentaro Ohki, MD PhD, Tanja A. Gruber, MD PhD, Rosemary Sutton, BSc MSc PhD, Agata Pastorczak, Tim Lammens, PhD, Frederic Lambert, MD, Chi Kong Li, MD, Enrique Carrillo de Santa Pau, PhD, Steve Hoffmann, MD PhD, Anja Möricke, MD, Christine J. Harrison, PhD FRCPath, Monique L. Den Boer, PhD, Paola De Lorenzo, Ronald W. Stam, PhD, Anke K. Bergmann, MD PhD, Rob Pieters, MDPhDMSc
Journal: Blood
Blood (2020) 136 (Supplement 1): 25–26.
https://doi.org/10.1182/blood-2020-139376
Published: 2020
Journal Articles

Acute Lymphoblastic Leukemia with Zinc-Finger Protein 384 (ZNF384)-Related Rearrangements: A Retrospective Analysis from the Ponte Di Legno Childhood ALL Working Group

Shinsuke Hirabayashi, Ellie Butler, Kentaro Ohki, MD PhD, Nobutaka Kiyokawa, MD PhD, Anke K. Bergmann, Judith M. Boer, PhD, Hélène Cavé, PharmD, PhD, Giovanni Cazzaniga, Allen Eng Juh Yeoh, Toshihiko Imamura, MD PhD, Hiroto Inaba, MD, Mignon L. Loh, MD, Ulrika Norén-Nyström, MD PhD, Agata Pastorczak, Lee-Yung Shih, MD, Marketa Zaliova, MD PhD, Oskar A Haas, Christine J. Harrison, PhD FRCPath, Anthony V. Moorman, Atsushi Manabe, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 652.
https://doi.org/10.1182/blood-2019-123236
Published: 2019
Journal Articles

Single Nucleotide Polymorphism Array-Based Signature of Genetic Ploidy Groups in Acute Lymphoblastic Leukemia

Thomas Creasey, MBBS, Amir Enshaei, PhD, Kathryn Watts, BSc, Gavin Cuthbert, BSc, Claire Schwab, PhD, Christine J. Harrison, PhD FRCPath, Ajay Vora, Adele K. Fielding, MBBS,PhDFRCP,FRCPath, Anthony V. Moorman
Journal: Blood
Blood (2019) 134 (Supplement_1): 1473.
https://doi.org/10.1182/blood-2019-122556
Published: 2019
Journal Articles

Molecular MRD Monitoring Is Feasible in the Majority of Children with AML and Is Highly Predictive of Outcome: Results from the International MyeChild01 Study

Jelena Jovanovic, PhD, Nicola Potter, PhD, Anju Kanda, MSc, Claire Schwab, PhD, Aimee E Jackson, MSc, Richard Dillon, MA, PhD MRCP, FRCPath, Anna Lawson, BSc, Manohursingh Runglall, MSc, Paresh Vyas, MD PhD, Paul Virgo, Geoff Shenton, Nicholas Heaney, Beki James, MD, Katharine Patrick, MD, Persis J Amrolia, FRCP, FRCPath, PhD, Jean-Hugues Dalle, MD PhD, Gerard Michel, MD, Andrew S. Moore, MBBS,FRACP,PhD, Hélène Lapillonne, MD PhD, Claude Preudhomme, PharmD, PhD, Guy Leverger, MD, Owen P Smith, MD, Andre Baruchel, MD, Yves Bertrand, MD, Arnaud Petit, MD PhD, Keith Wheatley, DPhil, Pamela R. Kearns, PhDFRCPC, Christine J. Harrison, PhD FRCPath, Brenda Gibson, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1393.
https://doi.org/10.1182/blood-2019-125257
Published: 2019
Journal Articles

Prognostic Impact of Chromosomal Abnormalities and Copy Number Alterations Among Adults with B-Cell Precursor Acute Lymphoblastic Leukaemia Treated on UKALL14

Anthony V. Moorman, Ellie Butler, Emilio Barretta, Amy A. Kirkwood, MSc, Claire Schwab, PhD, Thomas Creasey, MBBS, Daniel A. Leongamornlert, PhD, Elli Papaemmanuil, PhD, Pip Patrick, PhDMSc,MA, Laura Clifton-Hadley, PhDBSc, Bela Wrench, MBBS, MD MRCP, FRCPath, Tobias F Menne, MD PhD FRCPath, Andrew K McMillan, FRCP, Christine J. Harrison, PhD FRCPath, Clare J Rowntree, MBBS, PhD FRCP, FRCPath, David I Marks, MBBS, PhD FRCPath, Adele K. Fielding, MBBS,PhDFRCP,FRCPath
Journal: Blood
Blood (2019) 134 (Supplement_1): 288.
https://doi.org/10.1182/blood-2019-123642
Published: 2019
Journal Articles

Improved Treatment of Childhood ALL in Malaysia

Hamidah Alias, MMed (Paed), Sie Chong Doris Lau, MMed (Paed), C-Khai Loh, MRCPCH, Christine J. Harrison, PhD FRCPath, Jeyanthy Eswaran, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5828.
https://doi.org/10.1182/blood-2019-129402
Published: 2019
Journal Articles

Genetic and Genomic Characterisation of Older Adults with Acute Lymphoblastic Leukemia Treated on the UKALL14 and UKALL60+ Clinical Trials

Thomas Creasey, MBBS, Emilio Barretta, Amy A. Kirkwood, MSc, Claire Schwab, PhD, Pip Patrick, PhDMSc,MA, Laura Clifton-Hadley, PhDBSc, Bela Wrench, MBBS, MD MRCP, FRCPath, Tobias F Menne, MD PhD FRCPath, Andrew K McMillan, FRCP, Nicholas J. Morley, John A Snowden, BSc (Hons), MBChB, MD FRCP, FRCPath, Christine J. Harrison, PhD FRCPath, Daniel A. Leongamornlert, PhD, Elli Papaemmanuil, PhD, Clare J Rowntree, MBBS, PhD FRCP, FRCPath, David I Marks, MBBS, PhD FRCPath, Adele K. Fielding, MBBS,PhDFRCP,FRCPath, Anthony V. Moorman
Journal: Blood
Blood (2019) 134 (Supplement_1): 2746.
https://doi.org/10.1182/blood-2019-124395
Published: 2019
Journal Articles

A Genome-Wide CRISPR Screen Implicates MYC Dysregulation in TCF3 - PBX1 B-ALL

Ruth E Cranston, BSc, Paul B Sinclair, PhD, Matthew Bashton, PhD, Matthew P Selby, PhD, Christine J Harrison, PhD FRCPath
Journal: Blood
Blood (2018) 132 (Supplement 1): 3915.
https://doi.org/10.1182/blood-2018-99-110015
Published: 2018
Journal Articles

Constitutional Ring Chromosome 21 Predisposes to Acute Lymphoblastic Leukaemia (ALL) with iAMP21

Claire Schwab, Eigil Kjeldsen, MD DMSc, Nyla A. Heerema, PhD, Andrew Carroll, PhD, Matthew Bashton, PhD, Sarra Ryan, PhD, Anthony V. Moorman, PhD, Stephen P. Hunger, MD, Mignon L. Loh, MD, Henrik Hasle, MD PhD, Christine J Harrison, PhD FRCPath
Journal: Blood
Blood (2017) 130 (Supplement 1): 3978.
https://doi.org/10.1182/blood.V130.Suppl_1.3978.3978
Published: 2017
Journal Articles

Characteristics and Outcomes of Pediatric Patients with t(16;16)-AML: Results of a Case Series By the International BFM Study Group

Kim Klein, MD MSc, Valerie de Haas, MD PhD, Jonas Abrahamsson, MD PhD, Todd A Alonzo, PhD, Brenda Gibson, MD PhD, Christine J Harrison, PhD FRCPath, Henrik Hasle, MD PhD, Betsy A Hirsch, PhD, Guy Leverger, MD PhD, Franco Locatelli, MD PhD, Susana C. Raimondi, PhD, Jeffrey E Rubnitz, MD PhD, Dirk Reinhardt, MD PhD, Daisuke Tomizawa, MD PhD, Gertjan J.L. Kaspers, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2671.
https://doi.org/10.1182/blood.V130.Suppl_1.2671.2671
Published: 2017
Journal Articles

Intrachromosomal Amplification of Chromosome 21(iAMP21): Cytogenetic Characterisation and Outcome in Childhood B-Cell Precursor Acute Lymphoblastic Leukaemia (BCP-ALL). A Study On Behalf of the Ponte Di Legno International Childhood ALL Workshop

Christine J Harrison, PhD, FRCPath, Anthony V. Moorman, PhD, Claire Schwab, BSc, Nyla A. Heerema, PhD, Andrew J. Carroll, PhD, Oskar A. Haas, MD
Journal: Blood
Blood (2012) 120 (21): 293.
https://doi.org/10.1182/blood.V120.21.293.293
Published: 2012
Journal Articles

Immunoglobulin Heavy Chain Locus ( IGH@) Translocations in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL): Incidence and Risk Stratification

Lisa J Russell, PhD, Lisa Jones, BSc, Amy Erhorn, PhD, Amir Ensahei, PhD, Dino Masic, MRes, Helen Bentley, Karl S Laczko, Christine J Harrison, PhD, FRCPath
Journal: Blood
Blood (2012) 120 (21): 1274.
https://doi.org/10.1182/blood.V120.21.1274.1274
Published: 2012
Journal Articles

Genes Commonly Deleted in Childhood B-Cell Precursor ALL (BCP-ALL) Are Associated with Major Cytogenetic Subgroups

Claire Schwab, BSc, Lucy Chilton, Heather Morrison, BSc, Lisa Jones, BSc, Halima A Al-Shehhi, MD, Amy Erhorn, PhD, Lisa J Russell, PhD, Anthony V. Moorman, PhD, Christine J Harrison, PhD, FRCPath
Journal: Blood
Blood (2012) 120 (21): 1374.
https://doi.org/10.1182/blood.V120.21.1374.1374
Published: 2012
Journal Articles

Pediatric Acute Myeloid Leukemia with t(8;16)(p11;p13): A Distinct Clinical and Biological Entity. Results of a Collaborative Study by the International Berlin-Frankfurt-Mùˆnster AML Study Group.

Eva A Coenen, MD, C. Michel Zwaan, Christine J Harrison, PhD, FRCPath, Oskar A. Haas, Valerie de Haas, MD, PhD, V Mihal, Barbara De Moerloose, M.D., M Jeison, Jeffrey Rubnitz, MD, PhD, Daisuke Tomizawa, MD, Donna Johnston, MD, FRCPC, Todd A. Alonzo, PhD, Henrik Hasle, Dirk Reinhardt, MD, PhD, Anne Auvrignon, Michael Dworzak, Andrea Pession, Vincent H.J. van der Velden, John Swansbury, Kit Fai Wong, MD, Kiminori Terui, MD, PhD, Sureyya Savasan, MD, M Winstanley, G Vaitkeviciene, Martin Zimmermann, Rob Pieters, MD, PhD, Marry M. van den Heuvel-Eibrink
Journal: Blood
Blood (2012) 120 (21): 2516.
https://doi.org/10.1182/blood.V120.21.2516.2516
Published: 2012
Journal Articles

Clinical Relevance of Genes Commonly Deleted in Childhood B-Cell Precursor ALL (BCP-ALL)

Claire Schwab, BSc, Lucy Chilton, Amir Enshaie, PhD, Heather Morrison, BSc, Lisa Jones, BSc, Halima A Al-Shehhi, MD, Amy Erhorn, PhD, Lisa J Russell, Ajay J Vora, FRCPath, Christopher D Mitchell, FRCPCH, Sue M Richards, PhD, Nicholas Goulden, FRCPath, Sally Kinsey, FRCPath, Anthony V. Moorman, PhD, Christine J Harrison, PhD, FRCPath
Journal: Blood
Blood (2012) 120 (21): 290.
https://doi.org/10.1182/blood.V120.21.290.290
Published: 2012
Journal Articles

Delineation of Risk Factors in Paediatric Acute Lymphoblastic Leukaemia with Favourable Cytogenetics

Anthony V. Moorman, PhD, Amir Enshaie, PhD, Lucy Chilton, Claire Schwab, BSc, Thelma Tembo, Sue Richards, PhD, Sally Kinsey, FRCPath, Ajay J Vora, FRCPath, Chris Mitchell, MD, PhD, Christine J Harrison, PhD, FRCPath
Journal: Blood
Blood (2012) 120 (21): 292.
https://doi.org/10.1182/blood.V120.21.292.292
Published: 2012
Journal Articles

Leukemia Cells with a BCR-ABL1-Like signature and/or IKZF1 deletions, but Not High CRLF2 Expression, Are Predictive of an Unfavorable Prognosis in Childhood B Cell Precursor Acute Lymphoblastic Leukemia

Arian Van Der Veer, Esmee Waanders, PhD, Rob Pieters, MD, PhD, Marieke E. Willemse, Simon Reijmersdaal, Lisa J Russell, PhD, Christine J Harrison, PhD, FRCPath, William E. Evans, PharmD, Vincent H.J. van der Velden, PhD, Peter M. Hoogerbrugge, Frank N. van Leeuwen, PhD, G. Escherich, Martin Horstman, Leila mohammadi Khankahdani, Dimitris Rizopoulos, Hester A. de Groot-Kruseman, PhD, Edwin Sonneveld, PhD, Roland P. Kuiper, PhD, Monique L. Den Boer, PhD
Journal: Blood
Blood (2012) 120 (21): 880.
https://doi.org/10.1182/blood.V120.21.880.880
Published: 2012
Journal Articles

Treatment Intensification Improves Outcome in Children with iAMP21 positive ALL

Anthony V. Moorman, PhD, Hazel M Robinson, PhD, Sue M Richards, PhD, Claire Schwab, BSc, Christopher D Mitchell, FRCPCH, Nicholas Goulden, FRCPath, Ajay J Vora, FRCPath, Christine J Harrison, PhD, FRCPath
Journal: Blood
Blood (2012) 120 (21): 656.
https://doi.org/10.1182/blood.V120.21.656.656
Published: 2012
Journal Articles

Translocation t(6;9)(p22;q34)/DEK-NUP214 rearranged Pediatric AML: A Retrospective International Study

Julie Damgaard Sandahl, Eva A. Coenen, Erik Forestier, Jochen Harbott, Bertil Johansson, Gitte Kerndrup, Souichi Adachi, MD, PhD, Anne Auvrignon, H. Berna Beverloo, Lucy Chilton, Valerie de Haas, Christine J Harrison, PhD, FRCPath, Hiroto Inaba, Gertjan J.L. Kaspers, MD, PhD, Der-Cherng Liang, Kuo-Sin Lin, Riccardo Masetti, MD, Christine Perot, Andrea Pession, Prof, MD, Susana C. Raimondi, Katarina Reinhardt, PhD, Daisuke Tomizawa, Nils von Neuhoff, Marco Zecca, Marry M. van den Heuvel-Eibrink, Henrik Hasle
Journal: Blood
Blood (2012) 120 (21): 538.
https://doi.org/10.1182/blood.V120.21.538.538
Published: 2012