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Bryan D Young, BSc, PhD
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Journal Articles

Genomic Disruption of the Histone Methyltransferase SETD2 in Chronic Lymphocytic Leukemia

Matthew John Jerome Rose-Zerilli, PhD, Helen Parker, Marta Larrayoz, PhD, Ruth Clifford, Stuart Blakemore, Jennifer Edelmann, MD, Jane Gibson, Jun Wang, Viktor Ljungstrom, Tracy Chaplin, Ali Roghanian, Zadie Davis, Anton Parker, BSc, Eugen Tausch, MD, Stavroula Ntoufa, Sara Ramos, Pauline Robbe, MSc, Andrew J Steele, PhD, Graham Packham, PhD, Ana E. Rodriguez, Lee Brown, Feargal McNicholl, Francesco Forconi, MD DM, PhD FRCPath, Andrew R Pettitt, MRCP PhD, Peter Hillmen, Martin J.S. Dyer, Prof., Mark S Cragg, PhD, Bryan D Young, BSc, PhD, Claude Chelala, Richard Rosenquist, Kostas Stamatopoulos, MD, Stephan Stilgenbauer, Samantha Knight, Anna Schuh, MD PhD, David Oscier, Jonathan C Strefford, PhD
Journal: Blood
Blood (2015) 126 (23): 365.
https://doi.org/10.1182/blood.V126.23.365.365
Published: 2015
Journal Articles

SKIP Is Underexpressed in AML Leading to Sphingosine Kinase Hypofunction

Essam Ghazaly, MD PhD, Paul Smith, PhD, Chathunissa Gnanaranjan, MSc, Bryan D Young, BSc, PhD, Simon Joel, PhD, John G. Gribben, MD DSc, David C Taussig, PhD MRCP, FRCPath
Journal: Blood
Blood (2014) 124 (21): 5324.
https://doi.org/10.1182/blood.V124.21.5324.5324
Published: 2014
Journal Articles

Clonal Progression Including Evolution Of An iAMP21 Chromosome In Xenograft Models Of BCP-ALL

Paul B Sinclair, PhD, Lars Buechler, PhD, Joanna Cheng, MSc, Jake Clayton, MRes, Claire Schwab, BSc, Lisa Jones, BSc, Helen Blair, PhD, Lisa J Russell, PhD, Bryan D Young, BSc, PhD, Olaf Heidenreich, PhD, Christine J Harrison, PhD
Journal: Blood
Blood (2013) 122 (21): 2485.
https://doi.org/10.1182/blood.V122.21.2485.2485
Published: 2013
Journal Articles

Loss of Imprinting at the 14q32 Domain Leads to MicroRNA Overexpression in Acute Promyelocytic Leukemia

Floriana Manodoro, PhD, Jacek Marzec, Jun Wang, PhD, Tracy Chaplin, Jelena V Jovanovic, Moravcsik Eva, Iqbal Sameena, David Grimwade, MD, PhD, John Gribben, MD, DSc, Bryan D Young, BSc, PhD, Silvana Debernardi, PhD
Journal: Blood
Blood (2013) 122 (21): 2494.
https://doi.org/10.1182/blood.V122.21.2494.2494
Published: 2013
Journal Articles

Deletion Size Influences Clinical Outcome In Patients with Chronic Lymphocytic Leukemia; 13q Deletion Anatomy, Cooperating Lesions and Cancer Pathogenesis

Helen Parker, PhD, Matthew JJ Rose-Zerilli, PhD, Anton Parker, BSc, Tracy Chaplin, Anne Catherine Gardiner, BSc, Mike Griffiths, Andrew Collins, PhD, Bryan D Young, BSc, PhD, David Graham Oscier, Jonathan C. Strefford, BSc, PhD
Journal: Blood
Blood (2010) 116 (21): 757.
https://doi.org/10.1182/blood.V116.21.757.757
Published: 2010
Journal Articles

TNFRSF14 and EZH2 Mutations, Chr2p Gain and Copy Number Changes Targeting Genes Whose Proteins Interact with the Microenvironment In Transformed Follicular Lymphoma

David Wrench, Ajanthah Sangaralingam, Hira Tayyib, Myung-Kuk Kang, Ciaran O'Riain, Manu Gupta, Emanuela Carlotti, PhD, BSc, Csaba Bodor, Sameena Iqbal, Tracy Chaplin, Janet Matthews, Andrew James Clear, BSc, Andrew Davies, Silvia Montoto, MD, Maria Calaminici, Bryan D Young, BSc, PhD, John G. Gribben, MD, DSc, Andrew Lister, MD, Jude Fitzgibbon
Journal: Blood
Blood (2010) 116 (21): 799.
https://doi.org/10.1182/blood.V116.21.799.799
Published: 2010
Journal Articles

Discovery and Quantification of Small RNA Molecules In Acute Myeloid Leukaemia Using Solexa High-Throughput Clonal Sequencing

Silvana Debernardi, PhD, BSc, Jacek Marzec, BSc, PhD, Floriana Manodoro, BSc, PhD, Richard Dobson, BSc, Charles Mein, BSc, Alessandra Curtotti, BSc, Michael Mitchell, BSc, PhD, Bryan D Young, BSc, PhD
Journal: Blood
Blood (2010) 116 (21): 847.
https://doi.org/10.1182/blood.V116.21.847.847
Published: 2010
Journal Articles

Sequential SNP6.0 Microarray Analysis In Rai Stage 0 CLL Patients with Either Stable or Progressive Identifies Genomic Evolution In Both Cohorts

Matthew JJ Rose-Zerilli, PhD, Miqdad Rajibali, BSc, Helen Parker, PhD, Anton Parker, BSc, Anne Catherine Gardiner, BSc, Zadie Davis, PhD, Sarah Mold, BSc, Sharron Glide, BSc, Tracy Chaplin, Bryan D Young, BSc, PhD, David Graham Oscier, Jonathan C. Strefford, BSc, PhD
Journal: Blood
Blood (2010) 116 (21): 1696.
https://doi.org/10.1182/blood.V116.21.1696.1696
Published: 2010
Journal Articles

The Interlaboratory RObustness of Next-Generation Sequencing (IRON) Study: Deep-Sequencing Investigating TET2 , CBL , and KRAS Mutations In 4464 Amplicons by An International Group Involving 8 Laboratories.

Alexander Kohlmann, PhD, Hans-Ulrich Klein, MA, Silvia Bresolin, MSc, Tracy Chaplin, BSc, Harry Cuppens, PhD, Bernardo Garicochea, MD, PhD, Vera Grossmann, MA, Bozena Hanczaruk, BSc, Katja Hofer, MSc, Ilaria Iacobucci, PhD, Joop H Jansen, PhD, Truus te Kronnie, PhD, Louis van de Locht, BSc, Giovanni Martinelli, MD, Kim McGowan, BSc, Stephanie Stabentheiner, MSc, Bernd Timmermann, PhD, Peter Vandenberghe, MD, PhD, Bryan D Young, BSc, PhD, Martin Dugas, MD, Torsten Haferlach, MD
Journal: Blood
Blood (2010) 116 (21): 1665.
https://doi.org/10.1182/blood.V116.21.1665.1665
Published: 2010
Journal Articles

Genome Wide Study of DNA Methylation In AML

Marwa Saied, MBCHB, MD, Sabah Khaled, PhD, Thomas Down, PhD, Jacek Marzec, PhD, Paul Smith, PhD, Silvana Debernardi, PhD, BSc, Bryan D Young, BSc, PhD
Journal: Blood
Blood (2010) 116 (21): 3618.
https://doi.org/10.1182/blood.V116.21.3618.3618
Published: 2010
Journal Articles

Clonal Evolution of Multiple TET2 mutations In the Transformation of Chronic Myelomonocytic Leukemia to Acute Myeloid Leukemia and Its Subsequent Relapse

Robert D. Petty, BSc, Farideh Miraki-Moud, Tracy Chaplin, Grossmann Vera, Daverio Andrea, Finlay Macdougall, Maria Ronayne, Bryan D Young, BSc, PhD, Manoj Raghavan, MBBS, PhD
Journal: Blood
Blood (2010) 116 (21): 2699.
https://doi.org/10.1182/blood.V116.21.2699.2699
Published: 2010