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Austin E. Gillen
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Journal Articles

MCL1 Promotes Fatty Acid β-Oxidation in Therapy-Resistant AML through Cytoplasmic Sequestration of the Transcriptional Repressor IRF2BP2

Mark J Althoff, Mohd Minhajuddin, Brett M Stevens, Austin E Gillen, Regan Miller, Ana Vujovic, Sweta B Patel, William Showers, Stephanie Gipson, Monika Dzieciatkowska, Jana M Ellegast, Tristen Wright, Kimberly Stegmaier, Joseph T Opferman, Craig T Jordan
Journal: Blood
Blood (2024) 144 (Supplement 1): 39.
https://doi.org/10.1182/blood-2024-206516
Published: 2024
Journal Articles

STAT3-VDAC1 Axis Modulates Mitochondrial Function and Plays a Critical Role in the Survival of Leukemic Stem Cells

Kellen B Gil, Jamie Borg, Rosana Moreira Pereira, Anagha Inguva Sheth, Jeremy Rahkola, William Showers, Angelo D'Alessandro, Christine M. McMahon, Daniel A Pollyea, Austin E Gillen, Maria L Amaya
Journal: Blood
Blood (2024) 144 (Supplement 1): 2722.
https://doi.org/10.1182/blood-2024-207887
Published: 2024
Journal Articles

Omacetaxine and Azacitidine for Newly Diagnosed Patients with Myelodysplastic Syndromes and Excess Blasts

Daniel A Pollyea, Brett M Stevens, Diana Abbott, Maria L Amaya, Jonathan Gutman, Andrew Kent, Christine M. McMahon, Marc Schwartz, Clayton Smith, Jessica Dell-Martin, Connor Sohalski, Alexandra Ellis, Mary Haag, Jeffrey Schowinsky, Zenggang Pan, Sweta B Patel, Monica Ransom, Austin E Gillen, Eric M. Pietras, Craig T Jordan
Journal: Blood
Blood (2024) 144 (Supplement 1): 1828.
https://doi.org/10.1182/blood-2024-199336
Published: 2024
Journal Articles

Targeting Mitochondrial Calcium Uptake to Eradicate Venetoclax-Resistant Acute Myeloid Leukemia Stem Cells

Anagha Inguva Sheth, Krysta Engel, Hunter Tolison, Mark Jordan Althoff, Anna Krug, Maria L Amaya, Shanshan Pei, Tracy Young, Sweta B Patel, Mohd Minhajuddin, Regan Miller, Ian Shelton, Ana Vujovic, Courtney L Jones, Austin E Gillen, Monica Ransom, Sarah Staggs, Clayton Smith, Daniel A. Pollyea, Brett M Stevens, Craig T. Jordan
Journal: Blood
Blood (2023) 142 (Supplement 1): 588.
https://doi.org/10.1182/blood-2023-188285
Published: 2023
Journal Articles

Results from a Phase (Ph) 1 Clinical Study of the All-Oral Regimen of CC-486 and Venetoclax for Relapsed and Refractory Acute Myeloid Leukemia

Maria L Amaya, Christine M. McMahon, Marc Schwartz, Jonathan A Gutman, Connor Sohalski, Jennifer Tobin, Austin E Gillen, Anagha Inguva Sheth, Brett M Stevens, Clayton Smith, Craig T. Jordan, Daniel A. Pollyea
Journal: Blood
Blood (2023) 142 (Supplement 1): 2914.
https://doi.org/10.1182/blood-2023-182966
Published: 2023
Journal Articles

Intracellular Calcium Localization Mediates the Activity of Venetoclax in Targeting Acute Myeloid Leukemia Stem Cells

Anagha Inguva, Krysta L. Engel, Hunter Tolison, Mark J Althoff, Shanshan Pei, Maria L. Amaya, Anna Krug, Mohammad Minhajuddin, Courtney L Jones, Austin E. Gillen, Monica Ransom, Sarah Staggs, Daniel A. Pollyea, Clayton Smith, Brett M. Stevens, Craig T. Jordan
Journal: Blood
Blood (2022) 140 (Supplement 1): 5922–5923.
https://doi.org/10.1182/blood-2022-167787
Published: 2022
Journal Articles

Unique Metabolic Vulnerabilities of Myelodysplastic Syndrome Stem Cells

Brett M. Stevens, Krysta L. Engel, Austin E. Gillen, Rachel Culp-Hill, Angelo Dalessandro, Scott Alper, Daniel A. Pollyea, Craig T. Jordan
Journal: Blood
Blood (2021) 138 (Supplement 1): 1511.
https://doi.org/10.1182/blood-2021-150749
Published: 2021