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Ashley M Wellendorf
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Journal Articles

Inhibition of RHOA activity preserves the survival and hemostasis function of long-term cold-stored platelets

Shailaja Hegde, Huzoor Akbar, Ashley M. Wellendorf, Shawnagay Nestheide, James F. Johnson, Xueheng Zhao, Kenneth D. Setchell, Yi Zheng, Jose A. Cancelas
Journal: Blood
Blood (2024) 144 (16): 1732–1746.
https://doi.org/10.1182/blood.2023021453
Published: 2024
Includes: Supplemental data
Journal Articles

Scribble Is a Negative Regulator of Interferon-I Dependent Notch1 Activation in Adult Hematopoietic Stem Cells and Progenitors

Abhishek K Singh, Mark J Althoff, Saimul Islam, Ashley M Wellendorf, Jose A. Cancelas
Journal: Blood
Blood (2021) 138 (Supplement 1): 299.
https://doi.org/10.1182/blood-2021-151046
Published: 2021
Journal Articles

SERF1 Is Required for G-CSF Resistance of Start-Codon Mutant ELANE Granulocytic Precursors

Ramesh C Nayak, Lisa Trump, Sana Emberesh, Yarim Lee, Abhishek K Singh, Ashley M Wellendorf, Marshall S. Horwitz, Theodosia A. Kalfa, Carolyn Lutzko, Jose A. Cancelas
Journal: Blood
Blood (2021) 138 (Supplement 1): 433.
https://doi.org/10.1182/blood-2021-150899
Published: 2021
Journal Articles

Bone marrow regeneration requires mitochondrial transfer from donor Cx43-expressing hematopoietic progenitors to stroma

Karin Golan, Abhishek K. Singh, Orit Kollet, Mayla Bertagna, Mark J. Althoff, Eman Khatib-Massalha, Ekaterina Petrovich-Kopitman, Ashley M. Wellendorf, Hassan Massalha, Smadar Levin-Zaidman, Tali Dadosh, Breanna Bohan, Mruniya V. Gawali, Biplab Dasgupta, Tsvee Lapidot, Jose A. Cancelas
Journal: Blood
Blood (2020) 136 (23): 2607–2619.
https://doi.org/10.1182/blood.2020005399
Published: 2020
Includes: Multimedia, Supplemental data
Journal Articles

Mitochondrial Fate of Regenerative Hematopoietic Stem Cells Is Sequentially Controlled By Two Specific Conformations of Connexin-43

Abhishek K Singh, PhD, Ashley M Wellendorf, B.S., Breanna Bohan, B.S., Daniel Gonzalez-Nieto, PhD, Luis C Barrio, MD PhD, Ashwini S. Hinge, PhD, Marie-Dominique Filippi, PhD, Jose A. Cancelas, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 32–33.
https://doi.org/10.1182/blood-2020-141676
Published: 2020
Journal Articles

Yap1-Scribble polarization is required for hematopoietic stem cell division and fate

Mark J. Althoff, Ramesh C. Nayak, Shailaja Hegde, Ashley M. Wellendorf, Breanna Bohan, Marie-Dominique Filippi, Mei Xin, Q. Richard Lu, Hartmut Geiger, Yi Zheng, Maria T. Diaz-Meco, Jorge Moscat, Jose A. Cancelas
Journal: Blood
Blood (2020) 136 (16): 1824–1836.
https://doi.org/10.1182/blood.2019004113
Published: 2020
Includes: Multimedia, Supplemental data
Journal Articles

RhoA Targeting Suppresses Cold-Induced Platelet Lesion and Allows Refrigerated Storage of Functional Human Platelets to Fourteen Days

Shailaja N Hegde, PhD, Huzoor Akbar, PhD, Shawnagay Nestheide, BS, Ashley M Wellendorf, B.S., Breanna Bohan, James F Johnson, Yi Zheng, PhD, Jose A Cancelas, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 99.
https://doi.org/10.1182/blood-2019-125359
Published: 2019
Journal Articles

Bone Marrow Hematopoietic Connexin 43 Is Required for Mitotransfer and AMPK Dependent Mesenchymal Microenvironment Regeneration after Irradiation

Abhishek K Singh, PhD, Karin Golan, PhD, Mark J Althoff, BS, Ekaterina Petrovich-Kopitman, Ashley M Wellendorf, B.S., Fatima Mohmoud, B.S., Mayla Bertagna, MSc, Daniel Gonzalez-Nieto, PhD, Luis C Barrio, MD PhD, Tsvee Lapidot, PhD, Jose A Cancelas, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 872.
https://doi.org/10.1182/blood-2018-99-118292
Published: 2018
Journal Articles

Basal Polarity Complex Scribble Is Required for Leukemic Initiation and Propagation through Negative Regulation of Apical Polarity Complex Activator Cdc42 and Hypoxia Inducing Factor-1α

Shailaja N Hegde, PhD, Mark J Althoff, BS, Ramesh C. Nayak, PhD, Ashley M Wellendorf, B.S., Fatima Mohmoud, B.S., Gang Huang, PhD, Yi Zheng, PhD, Maria T Diaz-Meco, PhD, Jorge Moscat, PhD, Jose A Cancelas, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 551.
https://doi.org/10.1182/blood-2018-99-118919
Published: 2018
Journal Articles

Connexin-43 Is a Negative Regulator of Mitochondrial Fission, Mitophagy and Apoptosis of Dividing Hematopoietic Stem Cells through the Drp1-Pink1 Axis

Abhishek K Singh, PhD, Karin Golan, PhD, Mark J Althoff, BS, Ekaterina Petrovich-Kopitman, Ashley M Wellendorf, B.S., Fatima Mohmoud, B.S., Mayla Bertagna, MSc, Daniel Gonzalez-Nieto, PhD, Luis C Barrio, MD PhD, Tsvee Lapidot, PhD, Jose A Cancelas, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 639.
https://doi.org/10.1182/blood-2018-99-118663
Published: 2018
Journal Articles

Scribble Controls HSC Self-Renewal through Polarity-Dependent Activation of the Hippo Signaling Pathway

Mark J Althoff, BS, Ramesh C. Nayak, PhD, Shailaja Hegde, PhD, Ashley M Wellendorf, B.S., Fatima Mohmoud, B.S., Maria T Diaz-Meco, PhD, Jorge Moscat, PhD, Jose A Cancelas, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 710.
https://doi.org/10.1182/blood.V130.Suppl_1.710.710
Published: 2017