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Journal Articles

SERF1 Is Required for G-CSF Resistance of Start-Codon Mutant ELANE Granulocytic Precursors

Ramesh C Nayak, Lisa Trump, Sana Emberesh, Yarim Lee, Abhishek K Singh, Ashley M Wellendorf, Marshall S. Horwitz, Theodosia A. Kalfa, Carolyn Lutzko, Jose A. Cancelas

Blood (2021) 138 (Supplement 1): 433.

https://doi.org/10.1182/blood-2021-150899

Published: 2021

Journal Articles

Yap1-Scribble polarization is required for hematopoietic stem cell division and fate

Mark J. Althoff, Ramesh C. Nayak, Shailaja Hegde, Ashley M. Wellendorf, Breanna Bohan, Marie-Dominique Filippi, Mei Xin, Q. Richard Lu, Hartmut Geiger, Yi Zheng, Maria T. Diaz-Meco, Jorge Moscat, Jose A. Cancelas

Blood (2020) 136 (16): 1824–1836.

https://doi.org/10.1182/blood.2019004113

Published: 2020

Includes: Multimedia, Supplemental data

Journal Articles

Disruption of the Akt-FoxO Axis As a Safeguard Mechanism for the Hematopoietic Stem Cell Compartment during Chronic Metabolic Stress

Vinothini Govindarajah, PhD, Jung-Mi Lee, PhD, Michael Solomon, Bryan Goddard, Ramesh C. Nayak, PhD, Jose A Cancelas, MD, Damien Reynaud

Blood (2019) 134 (Supplement_1): 1201.

https://doi.org/10.1182/blood-2019-127222

Published: 2019

Journal Articles

Basal Polarity Complex Scribble Is Required for Leukemic Initiation and Propagation through Negative Regulation of Apical Polarity Complex Activator Cdc42 and Hypoxia Inducing Factor-1α

Shailaja N Hegde, PhD, Mark J Althoff, BS, Ramesh C. Nayak, PhD, Ashley M Wellendorf, B.S., Fatima Mohmoud, B.S., Gang Huang, PhD, Yi Zheng, PhD, Maria T Diaz-Meco, PhD, Jorge Moscat, PhD, Jose A Cancelas, MD PhD

Blood (2018) 132 (Supplement 1): 551.

https://doi.org/10.1182/blood-2018-99-118919

Published: 2018

Journal Articles

Scribble Controls HSC Self-Renewal through Polarity-Dependent Activation of the Hippo Signaling Pathway

Mark J Althoff, BS, Ramesh C. Nayak, PhD, Shailaja Hegde, PhD, Ashley M Wellendorf, B.S., Fatima Mohmoud, B.S., Maria T Diaz-Meco, PhD, Jorge Moscat, PhD, Jose A Cancelas, MD PhD

Blood (2017) 130 (Supplement 1): 710.

https://doi.org/10.1182/blood.V130.Suppl_1.710.710

Published: 2017

Journal Articles

Atypical Protein Kinase C λ/I Oncogenic Signaling through the Chromatin Modifier Satb2 Is Required for Leukemic B-Cell Progenitor Differentiation Arrest and Leukemogenesis

Ramesh C Nayak, Mark Jordan Althoff, BS, Ashley Wellendorf, Fatima Mohmoud, Maria Diaz-Meco, Jorge Moscat, Jose A. Cancelas, MD PhD

Blood (2016) 128 (22): 1201.

https://doi.org/10.1182/blood.V128.22.1201.1201

Published: 2016

Journal Articles

Sqstm1 Is Required to Retain Hematopoietic Stem Cell/ Progenitors As a Negative Regulator of Macrophage-Dependent Inflammatory Signaling in the Bone Marrow Osteoblastic Niche

Kyung-Hee Chang, PhD, Amitava Sengupta, PhD, Ramesh C Nayak, Angeles Duran, Sang Jun Lee, Ronald Pratt, Ashley Wellendorf, Sarah Hill, Marcus Watkins, Roberto Civitelli, Daniel T Starczynowski, PhD, Maria T Diaz-Meco, Jorge Moscat, Jose A Cancelas, MD PhD

Blood (2014) 124 (21): 350.

https://doi.org/10.1182/blood.V124.21.350.350

Published: 2014

Journal Articles

Neutropenia-associated ELANE mutations disrupting translation initiation produce novel neutrophil elastase isoforms

Timothy Tidwell, Jeremy Wechsler, Ramesh C. Nayak, Lisa Trump, Stephen J. Salipante, Jerry C. Cheng, Jean Donadieu, Taly Glaubach, Seth J. Corey, H. Leighton Grimes, Carolyn Lutzko, Jose A. Cancelas, Marshall S. Horwitz

Blood (2014) 123 (4): 562–569.

https://doi.org/10.1182/blood-2013-07-513242

Published: 2014

Includes: Supplemental data

Journal Articles

Myelopoiesis From Induced Pluripotent Stem Cells Reveals The Role Of Elastase Activity In The Pathogenesis Of Severe Congenital Neutropenia

Ramesh C Nayak, PH.D., Lisa Trump, PhD, H. Leighton Grimes, PhD, Carolyn Lutzko, PhD, Jose A. Cancelas, M.D. PhD.

Blood (2013) 122 (21): 442.

https://doi.org/10.1182/blood.V122.21.442.442

Published: 2013

Journal Articles

Hyperangiotensinemia Induces Stem Cell/Progenitor Mobilization and De-Adhesion From BM Endothelial Cells Through AT2R Signaling and Inhibition of RhoA Activity

Kyung-Hee Chang, PhD, Ramesh C Nayak, Ph.D., Katie Bezold, Ashley Ficker, Swarnava Roy, PhD, Xuan Zhou, Megan Pirman, Susan Dunn, Yi Zheng, PhD, Punam Malik, MD, Jose A. Cancelas, M.D. PhD

Blood (2012) 120 (21): 3466.

https://doi.org/10.1182/blood.V120.21.3466.3466

Published: 2012

Journal Articles

Kruppel-Like-Factor 5 (Klf-5) Controls Hematopoietic Stem Cell/Progenitor Bone Marrow Homing and Lodging Through Rab5-Mediated Expression of Active β 1 Integrin

Eri Taniguchi Ishikawa, PhD, Kyung-Hee Chang, PhD, H. Andre Olsson, Ph.D, Ramesh C Nayak, Ph.D., Ashley Ficker, Susan K Dunn, Amitava Sengupta, PhD, Jeffrey Whitsett, MD, H. Leighton Grimes, PhD, Jose A Cancelas, MD, PhD

Blood (2012) 120 (21): 113.

https://doi.org/10.1182/blood.V120.21.113.113

Published: 2012

Journal Articles

Role of Rab Proteins In Endocytosis and Trafficking of Factor VIIa and Endothelial Cell Protein C Receptor In Endothelial Cells.

Ramesh C Nayak, Ph.D., Shiva Keshava, Ph.D., Usha Pendurthi, Ph.D., L. Vijaya Mohan Rao, Ph.D.

Blood (2010) 116 (21): 1145.

https://doi.org/10.1182/blood.V116.21.1145.1145

Published: 2010

Journal Articles

Cystine 186–cystine 209 disulfide bond is not essential for the procoagulant activity of tissue factor or for its de-encryption

Hema Kothari, Ramesh C. Nayak, L. Vijaya Mohan Rao, Usha R. Pendurthi

Blood (2010) 115 (21): 4273–4283.

https://doi.org/10.1182/blood-2009-09-241356

Published: 2010

Journal Articles

Endothelial cell protein C receptor cellular localization and trafficking: potential functional implications

Ramesh C. Nayak, Prosenjit Sen, Samit Ghosh, Ramakrishnan Gopalakrishnan, Charles T. Esmon, Usha R. Pendurthi, L. Vijaya Mohan Rao

Blood (2009) 114 (9): 1974–1986.

https://doi.org/10.1182/blood-2009-03-208900

Published: 2009

Includes: Supplemental data

NARROW

SERF1 Is Required for G-CSF Resistance of Start-Codon Mutant ELANE Granulocytic Precursors

Yap1-Scribble polarization is required for hematopoietic stem cell division and fate

Disruption of the Akt-FoxO Axis As a Safeguard Mechanism for the Hematopoietic Stem Cell Compartment during Chronic Metabolic Stress

Basal Polarity Complex Scribble Is Required for Leukemic Initiation and Propagation through Negative Regulation of Apical Polarity Complex Activator Cdc42 and Hypoxia Inducing Factor-1α

Scribble Controls HSC Self-Renewal through Polarity-Dependent Activation of the Hippo Signaling Pathway

Atypical Protein Kinase C λ/I Oncogenic Signaling through the Chromatin Modifier Satb2 Is Required for Leukemic B-Cell Progenitor Differentiation Arrest and Leukemogenesis

Sqstm1 Is Required to Retain Hematopoietic Stem Cell/ Progenitors As a Negative Regulator of Macrophage-Dependent Inflammatory Signaling in the Bone Marrow Osteoblastic Niche

Neutropenia-associated ELANE mutations disrupting translation initiation produce novel neutrophil elastase isoforms

Myelopoiesis From Induced Pluripotent Stem Cells Reveals The Role Of Elastase Activity In The Pathogenesis Of Severe Congenital Neutropenia

Hyperangiotensinemia Induces Stem Cell/Progenitor Mobilization and De-Adhesion From BM Endothelial Cells Through AT2R Signaling and Inhibition of RhoA Activity

Kruppel-Like-Factor 5 (Klf-5) Controls Hematopoietic Stem Cell/Progenitor Bone Marrow Homing and Lodging Through Rab5-Mediated Expression of Active β 1 Integrin

Role of Rab Proteins In Endocytosis and Trafficking of Factor VIIa and Endothelial Cell Protein C Receptor In Endothelial Cells.

Cystine 186–cystine 209 disulfide bond is not essential for the procoagulant activity of tissue factor or for its de-encryption

Endothelial cell protein C receptor cellular localization and trafficking: potential functional implications

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American Society of Hematology

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American Society of Hematology

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