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Journal Articles

A New Risk Stratification Model (R2-ISS) in Newly Diagnosed Multiple Myeloma: Analysis of Mature Data from 7077 Patients Collected By European Myeloma Network within Harmony Big Data Platform

Mattia D'Agostino, MD, Juan-José Lahuerta, MD PhD, Ruth Wester, MD, Anders Waage, MD PhD, Uta Bertsch, Elena Zamagni, Maria-Victoria Mateos, MD PhD, Alessandra Larocca, Daniele Dall'Olio, Niels W. C. J. van de Donk, David Cairns, MSc, PhD, Serena Rocchi, Hans Salwender, MD, Joan Blade Creixenti, Bronno van der Holt, PhD, Castellani Gastone, Giovannino Ciccone, Andrea Capra, Jan Dürig, MD, Sara Bringhen, MD, Sonja Zweegman, MDPhD, Michele Cavo, Hartmut Goldschmidt, MD, Gordon Cook, MB ChB, PhD, Jesus Maria Hernández-Rivas, MD PhD, Jesus F. San-Miguel, MD PhD, Mario Boccadoro, Pieter Sonneveld, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 34–37.
https://doi.org/10.1182/blood-2020-137021
Published: 2020
Journal Articles

High-Risk Multiple Myeloma Patients Are Missed without Gene Expression Profiling

Martin H Van Vliet, Yan-Ting Chen, PhD, Erik H Van Beers, PhD, Rowan Kuiper, PhD, Erik T. Valent, PhD, Marieke Spaan, MSc, Carolina Terragna, Elena Zamagni, Michele Cavo, Stefania Oliva, Alessandra Larocca, Torsten Haferlach, MD, Wee-Joo Chng, MBBS, PhD FRCPath, FRCP, Anders Waage, MD PhD, M Duin, Pieter Sonneveld, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 23–24.
https://doi.org/10.1182/blood-2020-137389
Published: 2020
Journal Articles

Upfront Autologous Hematopoietic Stem-Cell Transplantation Improves Overall Survival in Comparison with Bortezomib-Based Intensification Therapy in Newly Diagnosed Multiple Myeloma: Long-Term Follow-up Analysis of the Randomized Phase 3 EMN02/HO95 Study

Michele Cavo, Francesca Gay, MD, Meral Beksac, MD, Meletios A Dimopoulos, Lucia Pantani, MD PhD, Maria Teresa Petrucci, Luca Dozza, MSc, Bronno Van Der Holt, PhD, Sonja Zweegman, MDPhD, Elena Zamagni, Giuseppe A. Palumbo, MD PhD, Francesca Patriarca, Monica Galli, Vladimir Maisnar, MD PhD MBA, Markus Hansson, MD, Angelo Belotti, Ludek Pour, MD, Paula F Ypma, MD PhD, Mariella Grasso, Sandra Croockewit, MD, Massimo Offidani, Renato Zambello, Anna Marina Liberati, MD, Niels Frost Andersen, MD PhD, Annemiek Broyl, MD PhD, Rossella Troia, PharmD, Pellegrino Musto, Heinz Ludwig, MD, Anna Maria Morelli, MD, Roman Hajek, MD, Christoph Driessen, MD, Anders Waage, MD PhD, Peter Gimsing, DO, PhD, Ulf-Henrik Mellqvist, MD PhD, Thilo Zander, MD, Mario Boccadoro, Pieter Sonneveld, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 37–38.
https://doi.org/10.1182/blood-2020-137575
Published: 2020
Journal Articles

A Prospective Phase 2 Study to Assess Minimal Residual Disease after Ixazomib, Lenalidomide and Dexamethasone Treatment for Newly Diagnosed Transplant Eligible Multiple Myeloma Patients

Raija Helena Silvennoinen, MDPhD, Anders Waage, MD PhD, Valdas Peceliunas, MD, Fredrik Schjesvold, MDPhD, Pekka Anttila, MD, Marjaana Säily, MD PhD, Mervi Putkonen, MD PhD, Kristina Carlson, MD, Einar Haukaas, MD, Marja Sankelo, MDPhD, Anu Partanen, MD PhD, Damian L. Szatkowski, MDPhDMSc, Markus Hansson, MD PhD, Anu Marttila, MD, Lucia Ahlberg, MD, Per Axelsson, MD, Birgitta Lauri, MD, Maija Helena Mikkola, MD, Conny Karlsson, MD, Johanna Abelsson, MD, Erik Ahlstrand, MD PhD, Anu Sikiö, MD, Monika Klimkowska, MD PhD, Reda Matuzeviciene, MD PhD, Mona Hoysaeter Fenstad, MD PhD, Sorella Ilveskero, MD PhD, Hareth Nahi, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 40–41.
https://doi.org/10.1182/blood-2020-138643
Published: 2020
Journal Articles

Validation and Improvement Opportunities of the Revised International Staging System for Multiple Myeloma: An Analysis on Mature Data from European Clinical Trials within the Harmony Big Data Platform

Mattia D'Agostino, MD, Anders Waage, MD PhD, Juan-José Lahuerta, MD PhD, Uta Bertsch, Elena Zamagni, MD, Lars Bullinger, Alessandra Larocca, Maria-Victoria Mateos, Niels W. C. J. Van De Donk, Hans Jürgen Salwender, MD, Joan Bladé, MD, Bronno van der Holt, PhD, Paola Tacchetti, Giovannino Ciccone, Sonja Zweegman, Hartmut Goldschmidt, Michele Cavo, Jesús San-Miguel, Pieter Sonneveld, Mario Boccadoro, Jesús María Hernández-Rivas, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1773.
https://doi.org/10.1182/blood-2019-124321
Published: 2019
Journal Articles

A Randomized Phase 2 Trial Comparing Carfilzomib-Dexamethasone Vs Observation As Maintenance after Induction with Carfilzomib-Cyclophosphamide-Dexamethasone in Salvage ASCT in Multiple Myeloma: A Trial By the Nordic Myeloma Study Group

Henrik Gregersen, MD PhD, Valdas Peceliunas, MD, Kari Remes, MD PhD, Fredrik H. Schjesvold, MD PhD, Niels Abildgaard, MD, Hareth Nahi, MD PhD, Niels Frost Andersen, MD PhD, Annette Juul Vangsted, MD PhD, Tobias Wirenfeldt Klausen, M.S., Carsten Helleberg, MD, Kristina Carlson, MD, Ulf Christian Frølund, MD, Per Axelsson, MD, Olga Stromberg, MD, Cecilie Hveding Blimark, PhD MD, Olle Linder, MD, Galina Tsykunova, MD, Anders Waage, MD PhD, Markus Hansson, MD PhD, Nina Gulbrandsen
Journal: Blood
Blood (2019) 134 (Supplement_1): 601.
https://doi.org/10.1182/blood-2019-122141
Published: 2019
Journal Articles

Incidence and Survival of Multiple Myeloma; A Population-Based Study on 10 961 Patients Diagnosed 1982-2017

Øystein Langseth, MD, Tor Åge Myklebust, M.sc, PhD, Tom Børge Johannesen, MD PhD, Øyvind Hjertner, MD PhD, Anders Waage, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4380.
https://doi.org/10.1182/blood-2019-129816
Published: 2019
Journal Articles

Glycosylationof Immunoglobulins Determine Bone Loss in Multiple Myeloma

Marita Westhrin, Vlado Kovcic, Albert Bondt, Stephanie Holst, Zejian Zhang, Anders Sundan, PhD, Tobias S. Slørdahl, Anders Waage, MD PhD, Manfred Wuhrer, Therese Standal
Journal: Blood
Blood (2019) 134 (Supplement_1): 4324.
https://doi.org/10.1182/blood-2019-122542
Published: 2019
Journal Articles

Real-World Treatment Patterns from the HUMANS Study in Multiple Myeloma in Denmark

Niels Abildgaard, MD, Anders Waage, MD PhD, Markus Hansson, MD PhD, Pekka Anttila, MD, Mate Szilcz, Yuanjun Ma, Katrine Hass Rubin, Lill-Brith von Arx, Sigurd Ørstavik, Nawal Bent-Ennakhil, Jonatan Freilich, François Gavini, Anders Green
Journal: Blood
Blood (2019) 134 (Supplement_1): 5030.
https://doi.org/10.1182/blood-2019-121953
Published: 2019
Journal Articles

Utilizing Multiple Linked Populations Registers to Estimate Incidence and Prevalence of Multiple Myeloma in Sweden and Denmark from the Real-World HUMANS Study

Markus Hansson, MD PhD, Niels Abildgaard, MD, Anders Waage, MD PhD, Pekka Anttila, MD, Anders Green, Katrine Hass Rubin, Lill-Brith von Arx, Mate Szilcz, Yuanjun Ma, Sigurd Ørstavik, Nawal Bent-Ennakhil, Jonatan Freilich, François Gavini
Journal: Blood
Blood (2019) 134 (Supplement_1): 5037.
https://doi.org/10.1182/blood-2019-121983
Published: 2019
Journal Articles

Ixazomib-Thalidomide-Low Dose Dexamethasone (ITd) Induction Followed By Maintenance Therapy with Ixazomib or Placebo in Newly Diagnosed Multiple Myeloma Patients Not Eligible for Autologous Stem Cell Transplantation; Results from the Randomized Phase II HOVON-126/Nmsg 21#13 Trial

Sonja Zweegman, MDPhD, Fredrik H. Schjesvold, MDPhD, Bronno van der Holt, PhD, Mark-David Levin, MDPhD, Claudia A.M. Stege, MD, Anders Waage, MD PhD, Maria B.L. Leijs, MD, Saskia K. Klein, MDPhD, Damian L. Szatkowski, MDPhDMSc, Per Axelsson, MD, Trung Hieu Do, MD, Dorota Knut-Bojanovska, Ellen van der Spek, MDPhD, Asta Svirskaite, Pino Poddighe, MDPhD, Marian Stevens-Kroef, MD, Markus Hansson, MD PhD, Niels WCJ van de Donk, MD PhD, Einar Haukas, MD, Pieter Sonneveld, MDPhD, Niels Abildgaard, MDPhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 800.
https://doi.org/10.1182/blood-2018-99-111650
Published: 2018
Journal Articles

Whole-Exome and mRNA Sequencing of Multiple Myeloma Reveal Transformation to a More High-Risk and Proliferative Tumor at Relapse

Kristine Misund, PhD, Davine Hofste Op Bruinink, MD, Eivind Coward, PhD, Remco Hoogenboezem, MSc, Even H Rustad, MD, Eivind Hovig, PhD, Anders Sundan, PhD, Ola Myklebost, PhD, Pieter Sonneveld, MD PhD, Anders Waage, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3157.
https://doi.org/10.1182/blood-2018-99-113553
Published: 2018
Journal Articles

Bortezomib-Based Therapy Overcomes the Adverse Impact of Renal Impairment in Transplant Eligible Patients: An Analysis of the Prospective Randomized EMN02/HO95 Study

Meletios A. Dimopoulos, Efstathios Kastritis, Roman Hajek, Luca Dozza, Meral Beksac, MD, Alessandra Larocca, Hans Erik Johnsen, MD Professor, Ulf-Henrik Mellqvist, MD, Anders Waage, MD PhD, Sonja Zweegman, MD PhD, Heinz Ludwig, MD, Lucia Pantani, MD, Andrew Spencer, MD, Anna Pascarella, Marina Martello, Susana Carvalho, Hlif Steingrimsdottir, MD, Claudia Cellini, MD, Petra Cornelisse, Rossella Troia, Patrizia Tosi, MD, Bronno van der Holt, Mario Boccadoro, Pieter Sonneveld, MDPhD, Michele Cavo, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4545.
https://doi.org/10.1182/blood.V130.Suppl_1.4545.4545
Published: 2017
Journal Articles

Ixazomib-Thalidomide-Low Dose Dexamethasone (ITd) Induction Followed By Maintenance Therapy with Ixazomib or Placebo in Newly Diagnosed Multiple Myeloma Patients Not Eligible for Autologous Stem Cell Transplantation; Initial Results from the Randomized Phase II HOVON-126/Nmsg 21.13 Trial

Sonja Zweegman, MD PhD, Bronno van der Holt, Fredrik H. Schjesvold, MDPhD, Mark-David Levin, PhD, Claudia A.M. Stege, MD, Anders Waage, MD PhD, Maria Berhardina Leijs, MD, Saskia Klein, MD, Damian L. Szatkowski, MDPhDMSc, A Broyl, MDPhD, Per Axelsson, MD, Trung Hieu Do, MD, Dorota Knut-Bojanovska, Ellen van der Spek, MD, Asta Svirskaite, Sonia Cunha, Markus Hansson, MD PhD, Pieter Sonneveld, MDPhD, Einar Haukaas, Niels Abildgaard, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 433.
https://doi.org/10.1182/blood.V130.Suppl_1.433.433
Published: 2017
Journal Articles

Frailty Predicts Survival and Toxicity in Newly Diagnosed Multiple Myeloma Patients Ineligible for Autologous Stem Cell Transplantation; Report of the HOVON-87/Nmsg-18 Study Group

Claudia A.M. Stege, MD, Bronno van der Holt, Ulf-Henrik Mellqvist, MD, Mark-David Levin, PhD, Morten Salomo, Niels Abildgaard, MD, Gerard Bos, MDPhD, Heleen Visser-Wisselaar, Markus Hansson, MD PhD, Annette van der Velden, MD, Wendy Deenik, MD, Astrid Gruber, MD PhD, Jules L.L.M. Coenen, MD, Torben Plesner, MD, Saskia Klein, MD, Bea Tanis, MD PhD, Damian L. Szatkowski, MDPhDMSc, Rolf Brouwer, MD PhD, Matthijs Westerman, MD, Maria Berhardina Leijs, MD, Harm Sinnige, Einar Haukaas, Klaas van der Hem, MD PhD, Marc Durian, MD, Vera Mattijssen, MD PhD, Peter Gimsing, DO, PhD, Niels WCJ Van De Donk, Marian Stevens-Kroef, PhD, Pieter Sonneveld, MDPhD, Anders Waage, MD PhD, Sonja Zweegman, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3146.
https://doi.org/10.1182/blood.V130.Suppl_1.3146.3146
Published: 2017
Journal Articles

A Gain-of-Function Mutation in EPO Gene Causes Familial Erythrocytosis

Jakub Zmajkovic, MS, Pontus Lundberg, PhD, Ronny Nienhold, PhD, Anders Sundan, PhD, Anders Waage, MD PhD, Radek C. Skoda, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1653.
https://doi.org/10.1182/blood.V130.Suppl_1.1653.1653
Published: 2017
Journal Articles

European Post-Approval Safety Study (PASS) of Relapsed/Refractory Multiple Myeloma (RRMM): Safety, Including SPM, in a Large Cohort of Patients Treated with Lenalidomide, Thalidomide, and Bortezomib

Barbara Gamberi, Miguel Hernandez, Christian Berthou, Eleni Tholouli, Elena Zamagni, Roman Hájek, Monique Minnema, Meletios A Dimopoulos, Jo Caers, Niels Frost Andersen, Bjorn Andreasson, Anders Waage, MD PhD, Gerard Crotty, Elisabeth Kueenburg, Barbara Rosettani, Antonia Di Micco, Pamela Bacon, Igor Blau
Journal: Blood
Blood (2016) 128 (22): 3331.
https://doi.org/10.1182/blood.V128.22.3331.3331
Published: 2016
Journal Articles

The Rev II Trial: Lenalidomide and Dexamethasone As Second Line Treatment in Myeloma Followed By Extended Lenalidomid Vs Len/Dex

Johan Lund, MD, Sigrid Karstorp, MD, Evren Alici, MD PhD, Astrid Gruber, MD PhD, Birgitta Lauri, MD, Cecilie Blimark, MD PhD, Agneta Swedin, MD PhD, Markus Hansson, MD PhD, Karin Forsberg, MD, Lucia Ahlberg, MD, Carlsson Conny, MD, Anders Waage, MD PhD, Peter Gimsing, Annette Juul Vangsted, MD PhD, Ulf Christian Frølund, MD, Mats Hardling, Ulf-Henrik Mellqvist, MD PhD, Hareth Nahi
Journal: Blood
Blood (2015) 126 (23): 3047.
https://doi.org/10.1182/blood.V126.23.3047.3047
Published: 2015
Journal Articles

Detection and Monitoring of BRAF and NRAS Mutant Clones in Myeloma Patients By Digital PCR of Circulating DNA

Even Holth Rustad, Hong Yan Dai, PhD, Eivind Coward, PhD, Kristine Misund, PhD, Anders Sundan, PhD, Anders Waage, MD PhD
Journal: Blood
Blood (2015) 126 (23): 4196.
https://doi.org/10.1182/blood.V126.23.4196.4196
Published: 2015
Journal Articles

Validation of the EMC92/SKY92 Signature in HOVON-87/Nmsg-18: Gene Expression Based Prognostication Is Applicable in Elderly Patients with Newly Diagnosed Multiple Myeloma

Mark van Duin, PhD, Rowan Kuiper, BSc, Martin van Vliet, PhD, Annemiek Broijl, MD PhD, Leonie de Best, MSc, Erik van Beers, PhD, Bronno Van Der Holt, PhD, Heleen Visser-Wisselaar, PhD, Lizanne Bosman, BSc, Belinda Dumee, BSc, Fanni van den Bosch, BSc, Michael Vermeulen, BSc, Jasper Koenders, BSc, Marian Stevens-Kroef, PhD, Anders Waage, MD PhD, Sonja Zweegman, MD PhD, Pieter Sonneveld, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2967.
https://doi.org/10.1182/blood.V126.23.2967.2967
Published: 2015