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Manfred Wuhrer
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Journal Articles

Anti-Platelet IgG-Fc Glycosylation As a Novel Regulator in Platelet Transfusion Refractoriness

Dirk-Jan Mons, Thijs van Osch, Farahnaz Rayadoost, Saskia van der Velden, Manfred Wuhrer, Mette D. Hazenberg, Gestur Vidarsson, Rick Kapur
Journal: Blood
Blood (2024) 144 (Supplement 1): 2643.
https://doi.org/10.1182/blood-2024-197879
Published: 2024
Journal Articles

Aberrant glycosylation of anti-SARS-CoV-2 spike IgG is a prothrombotic stimulus for platelets

Alexander P. Bye, Willianne Hoepel, Joanne L. Mitchell, Sophie Jégouic, Silvia Loureiro, Tanya Sage, Gestur Vidarsson, Jan Nouta, Manfred Wuhrer, Steven de Taeye, Marit van Gils, Neline Kriek, Nichola Cooper, Ian Jones, Jeroen den Dunnen, Jonathan M. Gibbins
Journal: Blood
Blood (2021) 138 (16): 1481–1489.
https://doi.org/10.1182/blood.2021011871
Published: 2021
Includes: Supplemental data
Journal Articles

Monoclonal immunoglobulins promote bone loss in multiple myeloma

Marita Westhrin, Vlado Kovcic, Zejian Zhang, Siv H. Moen, Tonje Marie Vikene Nedal, Albert Bondt, Stephanie Holst, Kristine Misund, Glenn Buene, Anders Sundan, Anders Waage, Tobias S. Slørdahl, Manfred Wuhrer, Therese Standal
Journal: Blood
Blood (2020) 136 (23): 2656–2666.
https://doi.org/10.1182/blood.2020006045
Published: 2020
Includes: Supplemental data
Journal Articles

Glycosylationof Immunoglobulins Determine Bone Loss in Multiple Myeloma

Marita Westhrin, Vlado Kovcic, Albert Bondt, Stephanie Holst, Zejian Zhang, Anders Sundan, PhD, Tobias S. Slørdahl, Anders Waage, MD PhD, Manfred Wuhrer, Therese Standal
Journal: Blood
Blood (2019) 134 (Supplement_1): 4324.
https://doi.org/10.1182/blood-2019-122542
Published: 2019
Journal Articles

Patients with Autoimmune Anti-Red Blood Cell IgG1 Have Different Total- and Autoantibody -IgG1 Glycosylation Compared to Healthy Controls

Myrthe E. Sonneveld, MD, Masja De Haas, MD PhD Prof., Carolien Koeleman, Peter Ligthart, Manfred Wuhrer, PhD Prof., C. Ellen Van der Schoot, MD PhD Prof., Gestur Vidarsson, PhD
Journal: Blood
Blood (2016) 128 (22): 93.
https://doi.org/10.1182/blood.V128.22.93.93
Published: 2016
Journal Articles

Alpha1-Antichymotrypsin Present in Therapeutic C1-Inhibitor Products Competes with Selectin - Sialyl Lewis X Interaction

Ruchira Engel, PhD, Laura Delvasto Nunez, Dorina Roem, Gerard van Mierlo, Stephanie Holst, Marinus H.J. Van Oers, MD PhD, Manfred Wuhrer, Prof, Diana Wouters, PhD, Sacha Zeerleder, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1008.
https://doi.org/10.1182/blood.V126.23.1008.1008
Published: 2015
Journal Articles

IgG Alloantibodies Against RBC Induced By Pregnancy or Transfusion Have Unique Glycosylation Patterns Which Correlate with Clinical Outcome of Hemolytic Disease of the Fetus or Newborn

Myrthe Elisabeth Sonneveld, MD, Rosina Plomp, Jon Admiraal, Carolien Koeleman, Agnes Hipgrave-Ederveen, Joke Koelewijn, PhD, Peter Ligthart, Masja De Haas, Prof, MD, Manfred Wuhrer, Prof, C. Ellen Van der Schoot, Prof, MD, Gestur Vidarsson, PhD
Journal: Blood
Blood (2015) 126 (23): 660.
https://doi.org/10.1182/blood.V126.23.660.660
Published: 2015
Journal Articles

Inhibition of FcγR-mediated phagocytosis by IVIg is independent of IgG-Fc sialylation and FcγRIIb in human macrophages

Sietse Q. Nagelkerke, Gillian Dekkers, Iwan Kustiawan, Fleur S. van de Bovenkamp, Judy Geissler, Rosina Plomp, Manfred Wuhrer, Gestur Vidarsson, Theo Rispens, Timo K. van den Berg, Taco W. Kuijpers
Journal: Blood
Blood (2014) 124 (25): 3709–3718.
https://doi.org/10.1182/blood-2014-05-576835
Published: 2014
Includes: Supplemental data
Journal Articles

A prominent lack of IgG1-Fc fucosylation of platelet alloantibodies in pregnancy

Rick Kapur, Iwan Kustiawan, Anne Vestrheim, Carolien A. M. Koeleman, Remco Visser, Helga K. Einarsdottir, Leendert Porcelijn, Dave Jackson, Belinda Kumpel, André M. Deelder, Dennis Blank, Björn Skogen, Mette Kjaer Killie, Terje E. Michaelsen, Masja de Haas, Theo Rispens, C. Ellen van der Schoot, Manfred Wuhrer, Gestur Vidarsson
Journal: Blood
Blood (2014) 123 (4): 471–480.
https://doi.org/10.1182/blood-2013-09-527978
Published: 2014
Includes: Supplemental data
Journal Articles

Skewing towards Decreased Fc-Fucosylation of Platelet-Alloantibodies in Pregnancy

Rick Kapur, MD, MSc, Anne Vestrheim, Carolien AM Koeleman, Leendert Porcelijn, MD, Dave Jackson, Belinda Kumpel, PhD, André M Deelder, PhD, Terje E Michaelsen, PhD, Masja de Haas, MD, PhD, C. Ellen Van der Schoot, MD, PhD, Manfred Wuhrer, PhD, Gestur Vidarsson, PhD
Journal: Blood
Blood (2012) 120 (21): 3331.
https://doi.org/10.1182/blood.V120.21.3331.3331
Published: 2012