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Journal Articles

Granulomonocytic Progenitors (GMPs) Are Key Target Cells of Azacitidine in MDS and AML

Ashfaq Ali, PhD, Justine Penneroux, Reinaldo Dal Bello Jr, Aline Massé, Samuel Quentin, Ashwin Unnikrishnan, PhD, Lucie Hernandez, Emmanuel Raffoux, MD, Raouf Benabelali, Aline Renneville, MDPhD, Claude Preudhomme, PharmD, PhD, John Pimanda, PhDFRACP,FRCPA,MBBS, Herve Dombret, MD, Jean Soulier, MDPhD, Pierre Fenaux, MD PhD, Emmanuelle Clappier, PharmD,PhD, Lionel Ades, MD PhD, Raphael Itzykson, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 587.
https://doi.org/10.1182/blood.V130.Suppl_1.587.587
Published: 2017
Journal Articles

Activity of OTX015 (MK-8628), a BET-Bromodomain Inhibitor, in Acute Myeloid Leukemia (AML) Progenitor Cells

Louise Roulin, Ashfaq Ali, Aline Masse, Marie-Magdelaine Coudé, Dominique Bluteau, Thorsten Braun, MD PhD, Jeannig Berrou, Olivier Bluteau, Marc Delord, Maria Eugenia Riveiro, Patrice EDOUARD Herait, MD, Jean Soulier, MD PhD, André Baruchel, MD, Claude Gardin, MD, Hervé Dombret, Raphaël Itzykson, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2588.
https://doi.org/10.1182/blood.V126.23.2588.2588
Published: 2015
Journal Articles

Bromodomain Inhibition By OTX015 Regulates c-MYC and HEXIM1 in a Panel of Human Acute Leukemia Cell Lines

Marie-Magdelaine Coudé, Thorsten Braun, Jeannig Berrou, Mélanie Dupont, Raphael Itzykson, Aline Masse, Emmanuel Raffoux, MD, Maria Eugenia Riveiro, Patrice Herait, MD, Andre Baruchel, MD, Hervé Dombret, MD PhD, Claude Gardin
Journal: Blood
Blood (2014) 124 (21): 5957.
https://doi.org/10.1182/blood.V124.21.5957.5957
Published: 2014
Journal Articles

Inhibition of TET2-mediated conversion of 5-methylcytosine to 5-hydroxymethylcytosine disturbs erythroid and granulomonocytic differentiation of human hematopoietic progenitors

Brief Report
Elodie Pronier, Carole Almire, Hayat Mokrani, Aparna Vasanthakumar, Audrey Simon, Barbara da Costa Reis Monte Mor, Aline Massé, Jean-Pierre Le Couédic, Frédéric Pendino, Bruno Carbonne, Jérôme Larghero, Jean-Luc Ravanat, Nicole Casadevall, Olivier A. Bernard, Nathalie Droin, Eric Solary, Lucy A. Godley, William Vainchenker, Isabelle Plo, François Delhommeau
Journal: Blood
Blood (2011) 118 (9): 2551–2555.
https://doi.org/10.1182/blood-2010-12-324707
Published: 2011
Includes: Supplemental data
Journal Articles

TET2 Is a Novel Tumor Suppressor Gene Inactivated in Myeloproliferative Neoplasms: Identification of a Pre-JAK2 V617F Event

Francois Delhommeau, Sabrina Dupont, Chloe James, MD, PhD, Aline Masse, Jean Pierre le Couedic, Veronique Della Valle, Antonio Alberdi, Philippe Dessen, Michaela Fontenay, Nicole Casadevall, MD, Jean Soulier, MD, PhD, Olivier Bernard, William Vainchenker
Journal: Blood
Blood (2008) 112 (11): lba-3.
https://doi.org/10.1182/blood.V112.11.lba-3.lba-3
Published: 2008
Journal Articles

The JAK2 617V > F mutation triggers erythropoietin hypersensitivity and terminal erythroid amplification in primary cells from patients with polycythemia vera

Sabrina Dupont, Aline Massé, Chloé James, Irène Teyssandier, Yann Lécluse, Frédéric Larbret, Valérie Ugo, Patrick Saulnier, Serge Koscielny, Jean Pierre Le Couédic, Nicole Casadevall, William Vainchenker, François Delhommeau
Journal: Blood
Blood (2007) 110 (3): 1013–1021.
https://doi.org/10.1182/blood-2006-10-054940
Published: 2007
Includes: Supplemental data
Journal Articles

Pure Heterozygous and Mixed JAK2 V617F Genotypes Result in Distinct Mechanisms of Erythrocytosis in Polycythemia Vera.

Sabrina Dupont, Aline Masse, Chloe James, Nicole Casadevall, William Vainchenker, Francois Delhommeau
Journal: Blood
Blood (2006) 108 (11): 662.
https://doi.org/10.1182/blood.V108.11.662.662
Published: 2006