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Alice Fabarius, PhD
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Journal Articles

High-Risk Additional Chromosomal Abnormalities in CML Herald Death By Blast Crisis Already at Low Blast Levels

Rüdiger Hehlmann, MD, Astghik Voskanyan, Michael Lauseker, Markus Pfirrmann, PhD, Lida Kalmanti, Sébastien Rinaldetti, Katharina Kohlbrenner, PhD, Claudia Haferlach, MD, Brigitte Schlegelberger, MD, Alice Fabarius, PhD, Stefan W Krause, MD, Hans-Jochem Kolb, MD, Andreas Neubauer, MD, Dieter K. Hossfeld, MD PhD, Christoph Nerl, MD PhD, Alois Gratwohl, MD, Gabriela M Baerlocher, MD, Andreas Burchert, MD, Tim H Brümmendorf, MD, Andreas Hochhaus, MD, Susanne Saussele, MD, Michele Baccarani, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 666.
https://doi.org/10.1182/blood-2019-127127
Published: 2019
Journal Articles

Accumulation of DNA Damage and Alteration of the DNA Damage Response in Chronic Myeloid Leukemia

Henning D. Popp, Vanessa Kohl, MSc, Johanna Flach, PhD, Susanne Brendel, MTA, Helga Kleiner, MTA, Wolfgang Seifarth, PhD, Christel Weiss, PhD, Susanne Saussele, MD, Wolf-Karsten Hofmann, MD PhD, Alice Fabarius, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5364.
https://doi.org/10.1182/blood-2019-122698
Published: 2019
Journal Articles

Anti-Leukemic Efficacy of Talazoparib and APE1 Inhibitor III Combined with Decitabine in Myeloid Malignancies

Vanessa Kohl, MSc, Susanne Brendel, MTA, Johanna Flach, PhD, Helga Kleiner, MTA, Christel Weiss, PhD, Wolfgang Seifarth, PhD, Daniel Nowak, MD, Wolf-Karsten Hofmann, MD PhD, Alice Fabarius, PhD, Henning D. Popp
Journal: Blood
Blood (2019) 134 (Supplement_1): 5056.
https://doi.org/10.1182/blood-2019-122672
Published: 2019
Journal Articles

Nilotinib Vs Nilotinib Plus Pegylated Interferon α (Peg-IFN) Induction and Nilotinib or Peg-IFN Maintenance Therapy for Newly Diagnosed BCR-ABL1 Positive Chronic Myeloid Leukemia Patients in Chronic Phase (TIGER Study): The Addition of Peg-IFN Is Associated with Higher Rates of Deep Molecular Response

Andreas Hochhaus, MD, Andreas Burchert, MD, Susanne Saussele, MD, Gabriela M Baerlocher, MD, Tim H Brümmendorf, MD, Paul La Rosée, MD, Dominik Heim, MD, Stefan W Krause, MD, Philipp D le Coutre, MD, Dietger Niederwieser, MD, Thoralf Lange, MD, Alice Fabarius, PhD, Mathias Hänel, MD, Frank Stegelmann, MD, Jiri Mayer, MD, Arthur Gil, MPH, Danny Himsel, MSc, Joerg Hasford, MD, Rüdiger Hehlmann, MD, Thomas Ernst, MD, Christian Fabisch, Dr.rer.MDc., Markus Pfirrmann, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 495.
https://doi.org/10.1182/blood-2019-130043
Published: 2019
Journal Articles

Comparison of RNA-Based Versus DNA-Based Quantitative KIT D816V Mutation Analysis Reveals Significant Disparity in Patients with Advanced Systemic Mastocytosis

Mohamad Jawhar, Nicole Naumann, Johannes Lübke, Juliana Schwaab, Oliver Hofmann, Thomas Kielsgaard Kristensen, Karl Sotlar, Verena Haselmann, Sven Schneider, Georgia Metzgeroth, Henning D. Popp, Alice Fabarius, PhD, Peter Bugert, Wolf-Karsten Hofmann, MD PhD, Andreas Reiter
Journal: Blood
Blood (2019) 134 (Supplement_1): 2955.
https://doi.org/10.1182/blood-2019-128811
Published: 2019
Journal Articles

Genotypes of the Gene Encoding the Membrane Transporter SLC22A4 Are Associated with Molecular Relapse-Free Survival after Discontinuation of Imatinib Therapy in Patients with Chronic Myeloid Leukemia

Katerina Machova, Ali Albeer, Vaclava Polivkova, Katerina Vlcanova, Alice Fabarius, PhD, Hana Klamová, MD PhD, Birgit Spiess, Cornelius Waller, Tim H Brümmendorf, MD, Jolanta Dengler, MD, Volker Kunzmann, MD PhD, Andreas Burchert, MD, Petra Bělohlávková, MD PhD, Satu Mustjoki, MD PhD, Edgar Faber, MD, Jiri Mayer, MD, Daniela Žáčková, MD PhD, Panayiotis Panayiotidis, MD, Johan Richter, MD PhD, Henrik Hjorth-Hansen, MD, Susanne Saussele, MD, Markus Pfirrmann, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1647.
https://doi.org/10.1182/blood-2019-129710
Published: 2019
Journal Articles

An Increased Bone Mineral Density As an Adverse Prognostic Factor in Patients with Systemic Mastocytosis

Mohamad Jawhar, Juliana Schwaab, Nicole Naumann, Georgia Metzgeroth, Alice Fabarius, PhD, Stefan O Schoenberg, Wolf-Karsten Hofmann, MD PhD, Philipp Riffel, Andreas Reiter
Journal: Blood
Blood (2019) 134 (Supplement_1): 4185.
https://doi.org/10.1182/blood-2019-129798
Published: 2019
Journal Articles

Final Evaluation of Randomized CML-Study IV: 10-Year Survival and Evolution of Terminal Phase

Rüdiger Hehlmann, MD, Michael Lauseker, PhD, Susanne Saussele, MD, Markus Pfirrmann, Stefan W. Krause, MD, Hans-Jochem Kolb, MD, Andreas Neubauer, MD, Dieter K. Hossfeld, Christoph Nerl, MD, Alois Gratwohl, MD, Gabriela M. Baerlocher, Dominik Heim, MD, Tim Henrik Bruemmendorf, Alice Fabarius, PhD, Claudia Haferlach, MD, Brigitte Schlegelberger, MD PhD, Martin C. Müller, MD, Sabine Jeromin, PhD, Ulrike Proetel, PhD, Katharina Kohlbrenner, PhD, Astghik Voskanyan, PhD, Sébastien Rinaldetti, Wolfgang Seifarth, PhD, Birgit Spiess, Leopold Balleisen, MD, Maria E Goebeler, MD, Mathias Hänel, MD, Anthony D. Ho, MD, J Dengler, C Falge, Lothar Kanz, MD, Claus-Henning Köhne, MD, PhD, Andreas Burchert, MD, Michael Kneba, MD PhD, Frank Stegelmann, MD, C Köhne, Hans-Walter Lindemann, C Waller, Michael Pfreundschuh, MD, Karsten Spiekermann, Wolfgang E Berdel, MD, L Müller, Matthias Edinger, MD, Jiri Mayer, Prof, MD SCs, Dietrich W Beelen, MD PhD, Martin Bentz, MD, Hartmut Link, MDPhD, Bernd Hertenstein, MD, R Fuchs, Martin Wernli, MD, F Schlegel, Rudolph Schlag, M de Wit, Lorenz Trümper, MD, H Hebarth, M Hahn, Jörg Thomalla, MD, Christof Scheid, MD, Philippe Schafhausen, MD, Walter Verbeek, MD, Michael J. Eckart, MD, Winfried Gassmann, MD PhD, Antonio Pezzutto, MD, Michael Schenk, Peter Brossart, MD, Thomas Geer, MD, Stephan Bildat, E Schäfer, Andreas Hochhaus, MD, Joerg Hasford
Journal: Blood
Blood (2017) 130 (Supplement 1): 897.
https://doi.org/10.1182/blood.V130.Suppl_1.897.897
Published: 2017
Journal Articles

Mast Cell Leukemia: Clinical Heterogeneity, Molecular Aberrations, Treatment Responses, Survival, and Prognostic Factors

Mohamad Jawhar, MD, Juliana Schwaab, MD, Manja Meggendorfer, PhD, Nicole Naumann, Hans-Peter Horny, MD, Karl Sotlar, MD, Torsten Haferlach, MD, Karla Schmitt, MD, Alice Fabarius, PhD, Peter Valent, MD, Wolf-Karsten Hofmann, MD, Nicholas C.P. Cross, PhD, Georgia Metzgeroth, MD, Andreas Reiter, MD
Journal: Blood
Blood (2016) 128 (22): 3109.
https://doi.org/10.1182/blood.V128.22.3109.3109
Published: 2016
Journal Articles

Clinical Characteristics and Treatment with Various Tyrosine Kinase Inhibitors in Patients with ETV6-ABL1 positive Eosinophilia-Associated Myeloproliferative Neoplasms

Andreas Reiter, MD, Gunay Ahmadova, MD, Mohamad Jawhar, MD, Andres Virchis, MD, Tim Somervaille, MDPhD, Mark Williams, MD, Bernd Schönberger, MD, Rebecca Frewin, FRCPath, MRCP, MBBS, BSc, Philipp J. Jost, MD, Annett Maschke, MD, Peter Keller, MD, Torsten Haferlach, MD, Nicole Naumann, Juliana Schwaab, MD, Alice Fabarius, PhD, Wolf-Karsten Hofmann, MD, Claudia Haferlach, MD, Nicholas C.P. Cross, PhD, Georgia Metzgeroth, MD
Journal: Blood
Blood (2016) 128 (22): 3114.
https://doi.org/10.1182/blood.V128.22.3114.3114
Published: 2016
Journal Articles

Inhibitory Effects of Midostaurin and Blu-285 on Myeloid Progenitor Cells Derived from Patients with Multi-Mutated KIT D816V+ Advanced Systemic Mastocytosis

Mohamad Jawhar, MD, Nicole Naumann, Sebastian Kluger, Juliana Schwaab, MD, Georgia Metzgeroth, MD, Erica K. Evans, PhD, Alexandra Gardino, PhD, Christoph Lengauer, PhD, Wolf-Karsten Hofmann, MD, Nicholas C.P. Cross, PhD, Alice Fabarius, PhD, Andreas Reiter, MD
Journal: Blood
Blood (2016) 128 (22): 1964.
https://doi.org/10.1182/blood.V128.22.1964.1964
Published: 2016
Journal Articles

γH2AX Foci Increase Across the Spectrum from Myelodysplastic Syndromes to Acute Myeloid Leukemias and Co-Localize with 53BP1 in Specific Patterns in the Context of an Impaired DNA Damage Response

Henning D Popp, MD, Susanne Brendel, Nicole Naumann, Thomas Henzler, MD, Wolf-Karsten Hofmann, MD, Alice Fabarius, PhD
Journal: Blood
Blood (2016) 128 (22): 5226.
https://doi.org/10.1182/blood.V128.22.5226.5226
Published: 2016
Journal Articles

Impact of Molecular Markers on Response and Resistance in Midostaurin-Treated Patients with Advanced Systemic Mastocytosis

Mohamad Jawhar, MD, Juliana Schwaab, MD, Nicole Naumann, Sebastian Kluger, Hans-Peter Horny, MD, Karl Sotlar, MD, Torsten Haferlach, MD, Georgia Metzgeroth, MD, Alice Fabarius, PhD, Peter Valent, MD, Wolf-Karsten Hofmann, MD, Nicholas C.P. Cross, PhD, Manja Meggendorfer, PhD, Andreas Reiter, MD
Journal: Blood
Blood (2016) 128 (22): 945.
https://doi.org/10.1182/blood.V128.22.945.945
Published: 2016
Journal Articles

Incidence and Prognostic Impact of Cytogenetics in Combination with Molecular Aberrations in Patients with Systemic Mastocytosis

Nicole Naumann, Mohamad Jawhar, MD, Juliana Schwaab, MD, Georgia Metzgeroth, MD, Henning D Popp, MD, Nada Khaled, MD, Hans-Peter Horny, MD, Karl Sotlar, MD, Peter Valent, MD, Claudia Haferlach, MD, Gudrun Göhring, MD, Brigitte Schlegelberger, Prof, MD, Manja Meggendorfer, PhD, Nicholas C.P. Cross, PhD, Wolf-Karsten Hofmann, MD, Andreas Reiter, MD, Alice Fabarius, PhD
Journal: Blood
Blood (2016) 128 (22): 947.
https://doi.org/10.1182/blood.V128.22.947.947
Published: 2016
Journal Articles

Quantitative Analysis of Patient-Specific Lesions in Primary and Xenografted Myelodysplastic Syndromes Reveals Complex Hierarchies and Subclonal Diversity That Evolve during Disease Progression

Johann-Christoph Jann, Daniel Nowak, Janina Wittig, Florian Nolte, Stephanie Fey, Verena Nowak, Julia Obländer, Jovita Pressler, Katja Müdder, Corinna Klein, Bettina Zens, Uwe Platzbecker, MD, Claudia Schönefeldt, Alice Fabarius, PhD, Helmut Blum, PhD, Torsten J Schulze, MD, Claudia Haferlach, MD, Andreas Trumpp, PhD, Wolf-Karsten Hofmann, Hind Medyouf, PhD, Maximilian Mossner
Journal: Blood
Blood (2014) 124 (21): 4604.
https://doi.org/10.1182/blood.V124.21.4604.4604
Published: 2014
Journal Articles

Molecular Profiling of Myeloid Progenitor Cells in Multi-Mutated Advanced Systemic Mastocytosis Identifies KIT D816V As a Distinct and Late Event

Mohamad Jawhar, MD, Juliana Schwaab, MD, Susanne Schnittger, PhD, Karl Sotlar, MD, Hans Peter Horny, MD, Georgia Metzgeroth, Sven Schneider, MD, Nadine Müller, Nicole Naumann, Christoph Walz, MD, Torsten Haferlach, Peter Valent, MD, Wolf-Karsten Hofmann, MD, Nicholas C.P. Cross, PhD, Alice Fabarius, PhD, Andreas Reiter, MD
Journal: Blood
Blood (2014) 124 (21): 3216.
https://doi.org/10.1182/blood.V124.21.3216.3216
Published: 2014
Journal Articles

A Two-Fold Rise of BCR-ABL Transcript Levels Advises BCR-ABL Mutation Analysis in Imatinib-Treated Chronic Myeloid Leukemia (CML) - an Analysis of the Randomized CML-Study IV

Benjamin Hanfstein, MD, Niklas Westhoff, MD, Rüdiger Hehlmann, MD, Susanne Saussele, MD, Michael Lauseker, PhD, Thomas Ernst, MD, Philipp Erben, MD, Christian Dietz, PhD, Alice Fabarius, PhD, Ulrike Proetel, MD, Susanne Schnittger, PhD, Stefan W. Krause, MD, Joerg Schubert, MD, Hermann Einsele, Mathias Hänel, MD, Jolanta Dengler, MD, Christiane Falge, MD, Lothar Kanz, MD, Andreas Neubauer, MD, Michael Kneba, MD, Frank Stegelmann, MD, Michael Pfreundschuh, Cornelius F. Waller, MD, Karsten Spiekermann, MD, Gabriela M. Baerlocher, MD, Markus Pfirrmann, PhD, Joerg Hasford, MD, Wolf-Karsten Hofmann, Andreas Hochhaus, MD, Martin C. Müller, MD
Journal: Blood
Blood (2014) 124 (21): 3138.
https://doi.org/10.1182/blood.V124.21.3138.3138
Published: 2014
Journal Articles

Development of a DNA-Based Targeted Assay Suitable for Accurate Quantification of Chromosomal Deletions in Myelodysplastic Syndromes with Deletion (5q) and Other Clonal Diseases

Johann-Christoph Jann, Daniel Nowak, Florian Nolte, Stephanie Fey, Verena Nowak, Julia Obländer, Jovita Pressler, Alice Fabarius, PhD, Claudia Haferlach, MD, Hind Medyouf, PhD, Wolf-Karsten Hofmann, Maximilian Mossner
Journal: Blood
Blood (2014) 124 (21): 1925.
https://doi.org/10.1182/blood.V124.21.1925.1925
Published: 2014
Journal Articles

Comparing the Prognostic Significance of Early Predictors of Survival in Chronic Myeloid Leukemia (CML) Treated with Imatinib - an Analysis of the Randomized CML-Study IV

Benjamin Hanfstein, MD, Michael Lauseker, PhD, Rüdiger Hehlmann, MD, Susanne Saussele, MD, Philipp Erben, MD, Christian Dietz, PhD, Alice Fabarius, PhD, Ulrike Proetel, MD, Lida Kalmanti, MD, Susanne Schnittger, PhD, Stefan W. Krause, MD, Jörg Schubert, MD, Hermann Einsele, Mathias Hänel, MD, Jolanta Dengler, MD, Christiane Falge, MD, Lothar Kanz, MD, Andreas Neubauer, MD, Michael Kneba, MD, Frank Stegelmann, MD, Michael Pfreundschuh, Cornelius F. Waller, MD, Karsten Spiekermann, MD, Gabriela M. Baerlocher, MD, Markus Pfirrmann, PhD, Joerg Hasford, MD, Wolf-Karsten Hofmann, Andreas Hochhaus, MD, Martin C. Müller, MD
Journal: Blood
Blood (2014) 124 (21): 156.
https://doi.org/10.1182/blood.V124.21.156.156
Published: 2014
Journal Articles

The Pattern Of Cytogenetic Aberrations In CML BC Stratified For Treatment

Christian Dietz, PhD, Lida Kalmanti, MD, Michael Lauseker, Claudia Haferlach, MD, Gudrun Göhring, MD, Brigitte Schlegelberger, MD, PhD, Martine Jotterand, MD, Barbara Heinze, MD, Dieter K. Hossfeld, MD, Rüdiger Hehlmann, MD, Andreas Hochhaus, MD, Martin C. Müller, MD, Benjamin Hanfstein, MD, Ulrike Proetel, MD, Annette Schreiber, MD, Stefan W. Krause, MD, Andreas Neubauer, MD, Cornelius F. Waller, MD, Markus Pfirrmann, PhD, Joerg Hasford, MD, Wolf-Karsten Hofmann, MD, Hans-Jochem Kolb, MD, Hermann Heimpel, MD, Susanne Saussele, MD, Alice Fabarius, PhD
Journal: Blood
Blood (2013) 122 (21): 2737.
https://doi.org/10.1182/blood.V122.21.2737.2737
Published: 2013