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Nicole Naumann
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Journal Articles

Redefining Prognosis in Patients with KIT D816V Positive Advanced Systemic Mastocytosis on KIT Inhibitors

Johannes Luebke, Nicole Naumann, Georgia Metzgeroth, Hans-Peter Horny, Karl Sotlar, Martina Rudelius, Alice Fabarius, Wolf-Karsten Hofmann, Juliana Schwaab, Andreas Reiter
Journal: Blood
Blood (2024) 144 (Supplement 1): 660.
https://doi.org/10.1182/blood-2024-193760
Published: 2024
Journal Articles

Diagnosis and Outcome of Patients with Idiopathic Hypereosinophilic Syndrome and Cardiac Involvement

Johannes Lübke, Anna Hohneck, Jan Leipe, Nicole Naumann, Alice Fabarius, Wolf-Karsten Hofmann, Georgia Metzgeroth, Theano Papavassilu, Andreas Reiter, Juliana Schwaab
Journal: Blood
Blood (2023) 142 (Supplement 1): 3196.
https://doi.org/10.1182/blood-2023-187249
Published: 2023
Journal Articles

Predicting the Clinical Course of Treatment with Midostaurin in Patients with Advanced Systemic Mastocytosis

Johannes Lübke, Nicole Naumann, Timo Brand, Hans-Peter Horny, Martina Rudelius, Karl Sotlar, Georgia Metzgeroth, Alice Fabarius, Wolf-Karsten Hofmann, Juliana Schwaab, Andreas Reiter
Journal: Blood
Blood (2023) 142 (Supplement 1): 1834.
https://doi.org/10.1182/blood-2023-182322
Published: 2023
Journal Articles

Response and Resistance to Cladribine in Patients with Advanced Systemic Mastocytosis: A Registry-Based Analysis

Johannes Lübke, Nicole Naumann, Sebastian Kreil, Georgia Metzgeroth, Hans-Peter Horny, Karl Sotlar, Nicholas C.P. Cross, Alice Fabarius, Peter Valent, Wolf-Karsten Hofmann, Juliana Schwaab, Andreas Reiter
Journal: Blood
Blood (2022) 140 (Supplement 1): 3970–3971.
https://doi.org/10.1182/blood-2022-163650
Published: 2022
Journal Articles

Comparison of RNA-Based Versus DNA-Based Quantitative KIT D816V Mutation Analysis Reveals Significant Disparity in Patients with Advanced Systemic Mastocytosis

Mohamad Jawhar, Nicole Naumann, Johannes Lübke, Juliana Schwaab, Oliver Hofmann, Thomas Kielsgaard Kristensen, Karl Sotlar, Verena Haselmann, Sven Schneider, Georgia Metzgeroth, Henning D. Popp, Alice Fabarius, PhD, Peter Bugert, Wolf-Karsten Hofmann, MD PhD, Andreas Reiter
Journal: Blood
Blood (2019) 134 (Supplement_1): 2955.
https://doi.org/10.1182/blood-2019-128811
Published: 2019
Journal Articles

An Increased Bone Mineral Density As an Adverse Prognostic Factor in Patients with Systemic Mastocytosis

Mohamad Jawhar, Juliana Schwaab, Nicole Naumann, Georgia Metzgeroth, Alice Fabarius, PhD, Stefan O Schoenberg, Wolf-Karsten Hofmann, MD PhD, Philipp Riffel, Andreas Reiter
Journal: Blood
Blood (2019) 134 (Supplement_1): 4185.
https://doi.org/10.1182/blood-2019-129798
Published: 2019
Journal Articles

A New Prognostic Score for Advanced Systemic Mastocytosis Based on Clinical and Genetic Characteristics of 210 Consecutive Patients

Mohamad Jawhar, Juliana Schwaab, Nicole Naumann, Georgia Metzgeroth, MD, Hans-Peter Horny, Karl Sotlar, Manja Meggendorfer, PhD, Torsten Haferlach, MD, Nicholas C.P. Cross, Alice Fabarius, Wolf-Karsten Hofmann, Peter Valent, Andreas Reiter, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 349.
https://doi.org/10.1182/blood-2018-99-115804
Published: 2018
Journal Articles

KIT D816 Mutated / CBF-Negative Acute Myeloid Leukemia (AML): A New Poor-Risk Subtype Associated with Systemic Mastocytosis (SM-AML)

Mohamad Jawhar, Konstanze Döhner, MD, Sebastian Kreil, Juliana Schwaab, Khalid Shoumariyeh, MD, Manja Meggendorfer, PhD, Lambert L.F. Span, Stephan Fuhrmann, Nicole Naumann, Hans-Peter Horny, Karl Sotlar, Boris Kubuschok, Nikolas von Bubnoff, Karsten Spiekermann, MD, Michael Heuser, MD, Georgia Metzgeroth, MD, Alice Fabarius, Stefan A Klein, MD, Wolf-Karsten Hofmann, Hanneke Kluin-Nelemans, Torsten Haferlach, MD, Hartmut Döhner, MD, Nicholas C.P. Cross, Wolfgang R. Sperr, Peter Valent, Andreas Reiter, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1535.
https://doi.org/10.1182/blood-2018-99-115895
Published: 2018
Journal Articles

Systemic Mastocytosis with Associated Acute Myeloid Leukemia (SM-AML): a Poor-Risk Multi-Mutated Disease That Follows a Distinct Diagnostic Algorithm and Requires High-Dose Stem Cell-Targeting Therapy

Mohamad Jawhar, MD, Sebastian Kreil, MD, Juliana Schwaab, Khalid Shoumariyeh, MD, Lambert L.F. Span, Stephan Fuhrmann, Nicole Naumann, Florian Nolte, MD, Daniela Heidenreich, MD, Nadine Z. Müller, MD, Hans-Peter Horny, Karl Sotlar, Torsten Haferlach, MD, Boris Kubuschok, Karsten Spiekermann, Michael Heuser, MD, Georgia Metzgeroth, MD, Alice Fabarius, Stefan Klein, MD, Wolf-Karsten Hofmann, MD, Nicholas C.P. Cross, PhD, Manja Meggendorfer, PhD, Hanneke Kluin-Nelemans, MD PhD, Wolfgang R. Sperr, MD, Peter Valent, MD, Andreas Reiter, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2916.
https://doi.org/10.1182/blood.V130.Suppl_1.2916.2916
Published: 2017
Journal Articles

Response and progression on midostaurin in advanced systemic mastocytosis: KIT D816V and other molecular markers

Clinical Trials & Observations
Mohamad Jawhar, Juliana Schwaab, Nicole Naumann, Hans-Peter Horny, Karl Sotlar, Torsten Haferlach, Georgia Metzgeroth, Alice Fabarius, Peter Valent, Wolf-Karsten Hofmann, Nicholas C. P. Cross, Manja Meggendorfer, Andreas Reiter
Journal: Blood
Blood (2017) 130 (2): 137–145.
https://doi.org/10.1182/blood-2017-01-764423
Published: 2017
Journal Articles

Mast Cell Leukemia: Clinical Heterogeneity, Molecular Aberrations, Treatment Responses, Survival, and Prognostic Factors

Mohamad Jawhar, MD, Juliana Schwaab, MD, Manja Meggendorfer, PhD, Nicole Naumann, Hans-Peter Horny, MD, Karl Sotlar, MD, Torsten Haferlach, MD, Karla Schmitt, MD, Alice Fabarius, PhD, Peter Valent, MD, Wolf-Karsten Hofmann, MD, Nicholas C.P. Cross, PhD, Georgia Metzgeroth, MD, Andreas Reiter, MD
Journal: Blood
Blood (2016) 128 (22): 3109.
https://doi.org/10.1182/blood.V128.22.3109.3109
Published: 2016
Journal Articles

Clinical Characteristics and Treatment with Various Tyrosine Kinase Inhibitors in Patients with ETV6-ABL1 positive Eosinophilia-Associated Myeloproliferative Neoplasms

Andreas Reiter, MD, Gunay Ahmadova, MD, Mohamad Jawhar, MD, Andres Virchis, MD, Tim Somervaille, MDPhD, Mark Williams, MD, Bernd Schönberger, MD, Rebecca Frewin, FRCPath, MRCP, MBBS, BSc, Philipp J. Jost, MD, Annett Maschke, MD, Peter Keller, MD, Torsten Haferlach, MD, Nicole Naumann, Juliana Schwaab, MD, Alice Fabarius, PhD, Wolf-Karsten Hofmann, MD, Claudia Haferlach, MD, Nicholas C.P. Cross, PhD, Georgia Metzgeroth, MD
Journal: Blood
Blood (2016) 128 (22): 3114.
https://doi.org/10.1182/blood.V128.22.3114.3114
Published: 2016
Journal Articles

γH2AX Foci Increase Across the Spectrum from Myelodysplastic Syndromes to Acute Myeloid Leukemias and Co-Localize with 53BP1 in Specific Patterns in the Context of an Impaired DNA Damage Response

Henning D Popp, MD, Susanne Brendel, Nicole Naumann, Thomas Henzler, MD, Wolf-Karsten Hofmann, MD, Alice Fabarius, PhD
Journal: Blood
Blood (2016) 128 (22): 5226.
https://doi.org/10.1182/blood.V128.22.5226.5226
Published: 2016
Journal Articles

Impact of Molecular Markers on Response and Resistance in Midostaurin-Treated Patients with Advanced Systemic Mastocytosis

Mohamad Jawhar, MD, Juliana Schwaab, MD, Nicole Naumann, Sebastian Kluger, Hans-Peter Horny, MD, Karl Sotlar, MD, Torsten Haferlach, MD, Georgia Metzgeroth, MD, Alice Fabarius, PhD, Peter Valent, MD, Wolf-Karsten Hofmann, MD, Nicholas C.P. Cross, PhD, Manja Meggendorfer, PhD, Andreas Reiter, MD
Journal: Blood
Blood (2016) 128 (22): 945.
https://doi.org/10.1182/blood.V128.22.945.945
Published: 2016
Journal Articles

Incidence and Prognostic Impact of Cytogenetics in Combination with Molecular Aberrations in Patients with Systemic Mastocytosis

Nicole Naumann, Mohamad Jawhar, MD, Juliana Schwaab, MD, Georgia Metzgeroth, MD, Henning D Popp, MD, Nada Khaled, MD, Hans-Peter Horny, MD, Karl Sotlar, MD, Peter Valent, MD, Claudia Haferlach, MD, Gudrun Göhring, MD, Brigitte Schlegelberger, Prof, MD, Manja Meggendorfer, PhD, Nicholas C.P. Cross, PhD, Wolf-Karsten Hofmann, MD, Andreas Reiter, MD, Alice Fabarius, PhD
Journal: Blood
Blood (2016) 128 (22): 947.
https://doi.org/10.1182/blood.V128.22.947.947
Published: 2016
Journal Articles

Inhibitory Effects of Midostaurin and Blu-285 on Myeloid Progenitor Cells Derived from Patients with Multi-Mutated KIT D816V+ Advanced Systemic Mastocytosis

Mohamad Jawhar, MD, Nicole Naumann, Sebastian Kluger, Juliana Schwaab, MD, Georgia Metzgeroth, MD, Erica K. Evans, PhD, Alexandra Gardino, PhD, Christoph Lengauer, PhD, Wolf-Karsten Hofmann, MD, Nicholas C.P. Cross, PhD, Alice Fabarius, PhD, Andreas Reiter, MD
Journal: Blood
Blood (2016) 128 (22): 1964.
https://doi.org/10.1182/blood.V128.22.1964.1964
Published: 2016
Journal Articles

Additional Mutations in SRSF2, ASXL1 and/or RUNX1 Identify a High Risk Group of Patients with KIT D816V + Advanced Systemic Mastocytosis

Mohamad Jawhar, Juliana Schwaab, MD, Susanne Schnittger, PhD, Manja Meggendorfer, PhD, Karl Sotlar, MD, Hans-Peter Horny, MD, Georgia Metzgeroth, MD, Sebastian Kluger, Nicole Naumann, Claudia Haferlach, MD, Torsten Haferlach, Peter Valent, MD, Wolf-Karsten Hofmann, MD, Alice Charlotte Fabarius, PhD, Nicholas C.P. Cross, PhD, Andreas Reiter, MD
Journal: Blood
Blood (2015) 126 (23): 349.
https://doi.org/10.1182/blood.V126.23.349.349
Published: 2015
Journal Articles

Molecular Profiling of Myeloid Progenitor Cells in Multi-Mutated Advanced Systemic Mastocytosis Identifies KIT D816V As a Distinct and Late Event

Mohamad Jawhar, MD, Juliana Schwaab, MD, Susanne Schnittger, PhD, Karl Sotlar, MD, Hans Peter Horny, MD, Georgia Metzgeroth, Sven Schneider, MD, Nadine Müller, Nicole Naumann, Christoph Walz, MD, Torsten Haferlach, Peter Valent, MD, Wolf-Karsten Hofmann, MD, Nicholas C.P. Cross, PhD, Alice Fabarius, PhD, Andreas Reiter, MD
Journal: Blood
Blood (2014) 124 (21): 3216.
https://doi.org/10.1182/blood.V124.21.3216.3216
Published: 2014