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Alex H. Chang
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Journal Articles

Sequential CD19 and CD22 CAR-T Therapy in Relapsed/Refractory Acute Lymphoblastic Leukemia

Tingting Yang, Yetian Dong, Mingming Zhang, Jingjing Feng, Shan Fu, Pingnan Xiao, Ruimin Hong, Huijun Xu, Jiazhen Cui, Simao Huang, Guoqing Wei, Alex H. Chang, He Huang, Yongxian Hu
Journal: Blood
Blood (2024) 144 (Supplement 1): 2818.
https://doi.org/10.1182/blood-2024-210124
Published: 2024
Journal Articles

Rituximab, Lenalidomide, and Zanubrutinib (ZR 2 ) with Sequential CAR-T Cell As First-Line Therapy for High-Risk Large B Cell Lymphoma

Mingming Zhang, Yongxian Hu, Guoqing Wei, Shan Fu, Jingjing Feng, Ruimin Hong, Alex H. Chang, He Huang
Journal: Blood
Blood (2024) 144 (Supplement 1): 91.
https://doi.org/10.1182/blood-2024-210462
Published: 2024
Journal Articles

A Single-Center, Single-Arm, Phase I Clinical Trial of Anti-BCMA/GPRC5D Bispecific CAR T-Cells in Patients with Refractory and Relapsed Multiple Myeloma with Extramedullary Disease

Ling Qiu, Shihui Ren, Ying He, Dan Chen, Sihan Lai, Baitao Dou, Mengjiao Li, Rou Shu, Alex H. Chang, Yi Su, Hao Yao, Fangyi Fan
Journal: Blood
Blood (2024) 144 (Supplement 1): 1028.
https://doi.org/10.1182/blood-2024-210226
Published: 2024
Journal Articles

Donor-Derived CD7 Chimeric Antigen Receptor T Cells for T-Cell Prolymphocytic Leukemia: Two Case Reports

Sihan Lai, Yisong Xiong, Yanrong Shuai, Xupai Zhang, Guangcui He, Hao Yao, Hui Yang, Ling Zhang, Rong Huang, Yi Su, Alex H. Chang, Hai Yi
Journal: Blood
Blood (2024) 144 (Supplement 1): 7204.
https://doi.org/10.1182/blood-2024-202015
Published: 2024
Journal Articles

Prior ASCT Has a Negative Impact on Outcomes in Relapsed/Refractory Multiple Myeloma Patients after BCMA CAR-T Therapy

Chunxiang Jin, Rongrong Chen, Shan Fu, Alex H. Chang, He Huang, Yongxian Hu
Journal: Blood
Blood (2024) 144 (Supplement 1): 7082.
https://doi.org/10.1182/blood-2024-201470
Published: 2024
Journal Articles

APRIL CAR-T Cell Therapy for Relapsed/Refractory Multiple Myeloma: A Phase I Clinical Trial

Wenxiao Li, Yongxian Hu, Mingming Zhang, Xinyi Lai, Mengyu Zhao, Shan Fu, Ruimin Hong, Alex H. Chang, He Huang
Journal: Blood
Blood (2024) 144 (Supplement 1): 7229.
https://doi.org/10.1182/blood-2024-209660
Published: 2024
Journal Articles

Long-Term Follow-up of Sequential Allogeneic Hematopoietic Stem Cell Transplantation in Relapsed/Refractory Acute Lymphoblastic Leukemia Patients Achieving MRD-Negative CR after CAR-T Therapy

Tingting Yang, Yetian Dong, Jimin Shi, Mingming Zhang, Jingjing Feng, Shan Fu, Pingnan Xiao, Ruimin Hong, Huijun Xu, Yi Luo, Yanmin Zhao, Jian Yu, Xiaoyu Lai, Huarui Fu, Yishan Ye, Jiazhen Cui, Simao Huang, Guoqing Wei, Alex H. Chang, He Huang, Yongxian Hu
Journal: Blood
Blood (2024) 144 (Supplement 1): 7420.
https://doi.org/10.1182/blood-2024-209418
Published: 2024
Journal Articles

Different T-Cell Activation Approaches Impact the Resulting CART-Cell Products and Possible Clinical Outcomes

Biping Deng, Zhaoli Liu, Xiaoming Qu, Yu'e Zhang, Zhongxin Zhang, Rong Luan, Lingli Zhang, Ming Ma, Xiai Wu, Rui Liu, Alex H. Chang, Kai Hu, Chunrong Tong
Journal: Blood
Blood (2024) 144 (Supplement 1): 4856.
https://doi.org/10.1182/blood-2024-203423
Published: 2024
Journal Articles

A Multi-Omic Single-Cell Landscape of Cytokine Release Syndrome in Multiple Myeloma Patients after Anti-BCMA CAR-T Cell Therapy

Yongxian HU, Xia Li, Penglei Jiang, Tingting Yang, Tianning Gu, Xiaohui Si, Yali Xie, Mingming Zhang, Guoqing Wei, Huijun Xu, Zenan Cen, Jiazhen Cui, Simao Huang, Fang Ni, Linqin Wang, Xiujian Wang, Xiangjun Zeng, Delin Kong, Houli Zhao, Alex H. Chang, Yanlei Zhang, Jin Zhang, Jinyan Huang, Pengxu Qian, He Huang
Journal: Blood
Blood (2023) 142 (Supplement 1): 101.
https://doi.org/10.1182/blood-2023-185236
Published: 2023
Journal Articles

Neither Conditioning Chemotherapy Nor GvHD-Prophylaxis: CD7 CAR-T Treatment Bridging to Haplo-HSCT

Yongxian Hu, Mingming Zhang, Tingting Yang, Ruirui Jing, Houli Zhao, Rongrong Chen, Tianning Gu, Pingnan Xiao, Ruimin Hong, Jingjing Feng, Shan Fu, Delin Kong, Huijun Xu, Jiazhen Cui, Simao Huang, Bin Liang, Guoqing Wei, Xiaolin Yuan, Qu Cui, Jiangtao Ren, Alex H. Chang, Dongrui Wang, He Huang
Journal: Blood
Blood (2023) 142 (Supplement 1): 1039.
https://doi.org/10.1182/blood-2023-185697
Published: 2023
Journal Articles

Dasatinib and CAR-T Cell Therapy for Newly Diagnosed Ph-Positive Acute Lymphoblastic Leukemia in Adults

Mingming Zhang, Yongxian Hu, Guoqing Wei, Shan Fu, Jingjing Feng, Ruimin Hong, Alex H. Chang, He Huang
Journal: Blood
Blood (2023) 142 (Supplement 1): 891.
https://doi.org/10.1182/blood-2023-186225
Published: 2023
Journal Articles

CD19/BCMA CAR-T Cell Therapy for Refractory Systemic Lupus Erythematosus - Safety and Preliminary Efficacy Data from a Phase I Clinical Study

Jingjing Feng, Yongxian HU, Alex H. Chang, He Huang
Journal: Blood
Blood (2023) 142 (Supplement 1): 4835.
https://doi.org/10.1182/blood-2023-186669
Published: 2023
Journal Articles

Early response observed in pediatric patients with relapsed/refractory Burkitt lymphoma treated with chimeric antigen receptor T cells

Clinical Trials & Observations
Wenqun Zhang, Jing Yang, Chunju Zhou, Bo Hu, Ling Jin, Biping Deng, Yang Liu, Shan Wang, Alex H. Chang, Juan Du, Zifen Gao, Yonghong Zhang
Journal: Blood
Blood (2020) 135 (26): 2425–2427.
https://doi.org/10.1182/blood.2019002008
Published: 2020
Includes: Supplemental data
Journal Articles

Sequential CD19-22 CAR T therapy induces sustained remission in children with r/r B-ALL

Clinical Trials & Observations
Jing Pan, Shiyu Zuo, Biping Deng, Xiuwen Xu, Chuo Li, Qinlong Zheng, Zhuojun Ling, Weiliang Song, Jinlong Xu, Jiajia Duan, Zelin Wang, Xinjian Yu, Alex H. Chang, Xiaoming Feng, Chunrong Tong
Journal: Blood
Blood (2020) 135 (5): 387–391.
https://doi.org/10.1182/blood.2019003293
Published: 2020
Includes: Supplemental data