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Journal Articles

Cereblon Deficiency Leads to Alteration in c-Myc Regulated Genes, Increased Glucose Uptake and Resistance to JQ1 Bromodomain Inhibition

Matthew S Beatty, PhD, Rebecca S Hesterberg, BA, Ying Han, MD, Eric Padron, MD, Adam W Mailloux, PhD, Sean Yoder, M.S, Anjali M Rajadhyaksha, PhD, Alan F. List, MD, Pearlie K Epling-Burnette, PhD

Blood (2015) 126 (23): 286.

https://doi.org/10.1182/blood.V126.23.286.286

Published: 2015

Journal Articles

A Phase II Study to Determine the Safety and Efficacy of the Oral Inhibitor of Indoleamine 2,3-Dioxygenase (IDO) Enzyme INCB024360 in Patients with Myelodysplastic Syndromes

Rami S Komrokji, MD, Sheng Wei, MD, Adam W Mailloux, PhD, Ling Zhang, MD, Eric Padron, MD, Jeffrey E. Lancet, MD, Sara Tinsley, ARNP, Lisa A Nardelli, BS, CCRP, Cynthia Benoit, RN, Javier Pinilla-Ibarz, MD PhD, Pearlie K Epling-Burnette, PhD, Alan F List, MD

Blood (2014) 124 (21): 4653.

https://doi.org/10.1182/blood.V124.21.4653.4653

Published: 2014

Journal Articles

Novel Predictor Of Lenalidomide Response In Non-del5q MDS Reveals Linkage To Molecular Mechanism: First Characterization Of T-Cell Function In Cereblon Homozygous Deficient Mice

Pearlie K Epling-Burnette, PhD, Ying Han, MD, Adam W Mailloux, PhD, Ling Zhang, MD, Jessica M. McDaniel, PhD, Rajadhyaksha Anjali, PhD, Sheng Wei, MD, Ritchie David, PhD, Paul Neeson, PhD, Rami S. Komrokji, MD, Alan List, MD

Blood (2013) 122 (21): 748.

https://doi.org/10.1182/blood.V122.21.748.748

Published: 2013

Journal Articles

Common γ Chain (γ c ) Cytokine Hypersensitivity Leads To T-Cell Homeostatic Deregulation Independent Of STAT3 Mutation In Large Granular Lymphocyte Leukemia

Adam W Mailloux, PhD, Jeff Painter, BS, Eric Padron, MD, Thomas P. Loughran, Jr., M.D., Pearlie K Epling-Burnette, PhD

Blood (2013) 122 (21): 1628.

https://doi.org/10.1182/blood.V122.21.1628.1628

Published: 2013

Journal Articles

Characterization Of RING Finger E3-Ubiquitin Ligase Cereblon In Hematopoietic Regulation

Ying Han, MD, Anjali M Rajadhyaksha, PhD, Adam W Mailloux, PhD, Jeff Painter, BS, Jessica M. McDaniel, PhD, Ling Zhang, MD, Pearlie K Epling-Burnette, PhD

Blood (2013) 122 (21): 1207.

https://doi.org/10.1182/blood.V122.21.1207.1207

Published: 2013

Journal Articles

Pluripotent Fibrosis Initiating Mesenchymal Stromal Cell Linked To Cytopenias In LGL Leukemia Through Genetic Reprogramming

Pearlie K. Epling-Burnette, PhD, Adam W. Mailloux, PhD, Ling Zhang, MD, Lynn C. Moscinski, MD, Sheng Wei, MD, Sean J Yoder, MS, Lubomir Sokol, MD, Ph.D, Loughran P Thomas, MD

Blood (2013) 122 (21): 1218.

https://doi.org/10.1182/blood.V122.21.1218.1218

Published: 2013

Journal Articles

Preclinical Characterization of KB003, a Novel Humaneered™ Monoclonal Anti-GM-CSF Antibody, Demonstrates That the GM-CSF Signaling Axis Is a Therapeutic Target in Chronic Myelomonocytic Leukemia (CMML)

Eric Padron, MD, Jeffrey S Painter, BS, Adam W Mailloux, PhD, Kathy L. McGraw, Jessica M. McDaniel, BS, Christopher Bebbington, DPhil., Mark Baer, PhD, Geoffrey Yarranton, PhD, Jeffrey E Lancet, MD, Rami S. Komrokji, MD, Alan F. List, MD, P.K. Epling-Burnette, PharmD, PhD

Blood (2012) 120 (21): 3793.

https://doi.org/10.1182/blood.V120.21.3793.3793

Published: 2012

Journal Articles

A Switch in Regulatory T-Cell Memory Phenotype Is Associated with Poor Survival in Lower Risk Myleodysplastic Syndrome Patients

Adam W Mailloux, PhD, Chiharu Sugimori, Rami S. Komrokji, MD, Jaroslaw P. Maciejewski, MD, PhD, Ronald Paquette, MD, PhD, Thomas P. Loughran, Jr., MD, Alan F. List, MD, P.K. Epling-Burnette, PharmD, PhD

Blood (2011) 118 (21): 1703.

https://doi.org/10.1182/blood.V118.21.1703.1703

Published: 2011

Journal Articles

GM-CSF Signaling Abnormalities in Chronic Myelomonocytic Leukemia

Eric Padron, MD, Jeffrey S. Painter, B.S., Adam W Mailloux, PhD, Jessica M. McDaniel, BS, Christopher Bebbington, DPhil., Mark Baer, PhD, Rami S. Komrokji, MD, Alan F. List, MD, Pearlie K Epling-Burnette, Pharm D, PhD

Blood (2011) 118 (21): 1713.

https://doi.org/10.1182/blood.V118.21.1713.1713

Published: 2011

Journal Articles

Human Telomerase Reverse Transcriptase (hTERT) Deficiency in Myelodysplastic Syndrome (MDS) Demonstrates Mechanistic Linkage to Aplastic Anemia Pathophysiology

Lili Yang, PhD, Adam W Mailloux, PhD, Dana E Rollison, PhD, Jong Park, PhD, Jeffrey S. Painter, B.S., Rami S. Komrokji, MD, Jaroslaw P Maciejewski, MD, PhD, Ronald Paquette, MD, PhD, Thomas P. Loughran, Jr., MD, Sheng Wei, MD, Alan F. List, MD, Pearlie K Epling-Burnette, Pharm D, PhD

Blood (2011) 118 (21): 791.

https://doi.org/10.1182/blood.V118.21.791.791

Published: 2011

Journal Articles

Cytopenias in Large Granular Lymphocyte Leukemia Are Mediated by Pro-Fibrotic Mesenchymal Stem Cells in the Bone Marrow Niche with Functional Restoration by FGFb

Adam W Mailloux, PhD, Ling Zhang, MD, Lili Yang, PhD, Cody Wei, Lubomir Sokol, MD, PhD, Lynn Moscinski, MD, John M. Bennett, MD, Thomas P. Loughran, Jr., MD, P.K. Epling-Burnette, PharmD, PhD

Blood (2011) 118 (21): 932.

https://doi.org/10.1182/blood.V118.21.932.932

Published: 2011

Journal Articles

Altered Collagen Production by Dysfunctional Mesenchymal Stem Cells Is Linked to T Cell Large Granular Lymphocyte Leukemia Pathophysiology.

Adam W. Mailloux, PhD, Fanqi Bai, MD, Ling Zhang, MD, Eric Padron, MD, Lili Yang, PhD, Cody Wei, Amber Schmidt, Lubomir Sokol, MD, PhD, Dung-Tsa Chen, PhD, Thomas P. Loughran, Jr., MD, Alan F. List, MD, P. K. Epling-Burnette, PharmD, PhD

Blood (2010) 116 (21): 2595.

https://doi.org/10.1182/blood.V116.21.2595.2595

Published: 2010

NARROW

Cereblon Deficiency Leads to Alteration in c-Myc Regulated Genes, Increased Glucose Uptake and Resistance to JQ1 Bromodomain Inhibition

A Phase II Study to Determine the Safety and Efficacy of the Oral Inhibitor of Indoleamine 2,3-Dioxygenase (IDO) Enzyme INCB024360 in Patients with Myelodysplastic Syndromes

Novel Predictor Of Lenalidomide Response In Non-del5q MDS Reveals Linkage To Molecular Mechanism: First Characterization Of T-Cell Function In Cereblon Homozygous Deficient Mice

Common γ Chain (γ c ) Cytokine Hypersensitivity Leads To T-Cell Homeostatic Deregulation Independent Of STAT3 Mutation In Large Granular Lymphocyte Leukemia

Characterization Of RING Finger E3-Ubiquitin Ligase Cereblon In Hematopoietic Regulation

Pluripotent Fibrosis Initiating Mesenchymal Stromal Cell Linked To Cytopenias In LGL Leukemia Through Genetic Reprogramming

Preclinical Characterization of KB003, a Novel Humaneered™ Monoclonal Anti-GM-CSF Antibody, Demonstrates That the GM-CSF Signaling Axis Is a Therapeutic Target in Chronic Myelomonocytic Leukemia (CMML)

A Switch in Regulatory T-Cell Memory Phenotype Is Associated with Poor Survival in Lower Risk Myleodysplastic Syndrome Patients

GM-CSF Signaling Abnormalities in Chronic Myelomonocytic Leukemia

Human Telomerase Reverse Transcriptase (hTERT) Deficiency in Myelodysplastic Syndrome (MDS) Demonstrates Mechanistic Linkage to Aplastic Anemia Pathophysiology

Cytopenias in Large Granular Lymphocyte Leukemia Are Mediated by Pro-Fibrotic Mesenchymal Stem Cells in the Bone Marrow Niche with Functional Restoration by FGFb

Altered Collagen Production by Dysfunctional Mesenchymal Stem Cells Is Linked to T Cell Large Granular Lymphocyte Leukemia Pathophysiology.

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American Society of Hematology

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American Society of Hematology

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