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Carfilzomib or bortezomib with melphalan-prednisone for transplant-ineligible patients with newly diagnosed multiple myeloma
Venetoclax plus R- or G-CHOP in non-Hodgkin lymphoma: results from the CAVALLI phase 1b trial
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BLOOD COMMENTARIES
PLENARY PAPER
REVIEW ARTICLE
CLINICAL TRIALS AND OBSERVATIONS
Carfilzomib or bortezomib with melphalan-prednisone for transplant-ineligible patients with newly diagnosed multiple myeloma
Clinical Trials & Observations
Thierry Facon,Jae Hoon Lee,Philippe Moreau,Ruben Niesvizky,Meletios Dimopoulos,Roman Hajek,Ludek Pour,Artur Jurczyszyn,Lugui Qiu,Zandra Klippel,Anita Zahlten-Kumeli,Muhtarjan Osman,Bruno Paiva,Jesus San-Miguel
Venetoclax plus R- or G-CHOP in non-Hodgkin lymphoma: results from the CAVALLI phase 1b trial
Clinical Trials & Observations
Andrew D. Zelenetz,Gilles Salles,Kylie D. Mason,Carla Casulo,Steven Le Gouill,Laurie H. Sehn,Herve Tilly,Guillaume Cartron,Martine E. D. Chamuleau,Andre Goy,Constantine S. Tam,Pieternella J. Lugtenburg,Adam M. Petrich,Arijit Sinha,Divya Samineni,Sylvia Herter,Ellen Ingalla,Edith Szafer-Glusman,Christian Klein,Deepak Sampath,Martin Kornacker,Mehrdad Mobasher,Franck Morschhauser
IMMUNOBIOLOGY AND IMMUNOTHERAPY
Dominant activating RAC2 mutation with lymphopenia, immunodeficiency, and cytoskeletal defects
Amy P. Hsu,Agnes Donkó,Megan E. Arrington,Muthulekha Swamydas,Danielle Fink,Arundhoti Das,Omar Escobedo,Vincent Bonagura,Paul Szabolcs,Harry N. Steinberg,Jenna Bergerson,Amanda Skoskiewicz,Melanie Makhija,Joie Davis,Ladan Foruraghi,Cindy Palmer,Ramsay L. Fuleihan,Joseph A. Church,Avinash Bhandoola,Michail S. Lionakis,Sharon Campbell,Thomas L. Leto,Douglas B. Kuhns,Steven M. Holland
RED CELLS, IRON, AND ERYTHROPOIESIS
BLOOD WORK
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Cover Image
Cover Image
COS-7 cells transfected with wild-type RAC2 and green fluorescent protein expression vectors. Staining of RAC2 (red) and F-actin (orange) shows a nascent phagocytic cup with high levels of RAC2 protein (cell on right). Unlike mutant RAC2[E62K], overexpression of normal RAC2[wild-type] does not affect actin formation. See the article by Hsu et al on page 1977.
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