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Issue Archive

Volume 6, Issue 24
December 27 2022
Issue Cover

Table of Contents

EDITORIAL

Celebrating a year of clinical and translational research in Blood Advances
Catherine M. Bollard,Andrew Weyrich
View Articletitled, Celebrating a year of clinical and translational research in <em>Blood Advances</em>

STIMULUS REPORTS

Novel insights into mouse models of ectopic proplatelet release
Markus Spindler,Wolfgang Bergmeier,Theresia E. B. Stradal,Jinyi Zhang,Katherine A. Siminovitch,Leo Nicolai,Annegret Reinhold,Markus Bender
View Articletitled, Novel insights into mouse models of ectopic proplatelet release
Supplemental data
Haptoglobin 1 allele predicts higher serum haptoglobin concentration and lower multiorgan failure risk in sickle cell disease
Clinical Trials & Observations
Maria A. Ruiz,Binal N. Shah,Guohui Ren,Faiz Hussain,Franklin Njoku,Roberto F. Machado,Victor R. Gordeuk,Santosh L. Saraf
View Articletitled, Haptoglobin 1 allele predicts higher serum haptoglobin concentration and lower multiorgan failure risk in sickle cell disease
Supplemental data

SYSTEMATIC REVIEW

Immunogenicity of SARS-CoV-2 vaccines in patients with multiple myeloma: a systematic review and meta-analysis
Nipat Chuleerarux,Kasama Manothummetha,Chatphatai Moonla,Anawin Sanguankeo,Olivia S. Kates,Nattiya Hirankarn,Kasidis Phongkhun,Jaedvara Thanakitcharu,Surachai Leksuwankun,Tanaporn Meejun,Achitpol Thongkam,Thanuthong Mongkolkaew,M. Veronica Dioverti,Pattama Torvorapanit,Nattapong Langsiri,Navaporn Worasilchai,Rongpong Plongla,Ariya Chindamporn,Shilpa Gopinath,Pitchaphon Nissaisorakarn,Tany Thaniyavarn,Saman Nematollahi,Nitipong Permpalung
View Articletitled, Immunogenicity of SARS-CoV-2 vaccines in patients with multiple myeloma: a systematic review and meta-analysis
Supplemental data

CLINICAL TRIALS AND OBSERVATIONS

Patient perspectives on testing for clonal hematopoiesis of indeterminate potential
Clinical Trials & Observations
Tal Sella,Geoffrey G. Fell,Peter G. Miller,Christopher J. Gibson,Shoshana M. Rosenberg,Craig Snow,Daniel G. Stover,Kathryn J. Ruddy,Jeffrey M. Peppercorn,Lidia Schapira,Virginia F. Borges,Steven E. Come,Ellen Warner,Elizabeth Frank,Donna S. Neuberg,Benjamin L. Ebert,Ann H. Partridge
View Articletitled, Patient perspectives on testing for clonal hematopoiesis of indeterminate potential
Supplemental data
Increasing tissue requirements in lymphoma trials may exclude patients with high-risk disease or worse prognosis
Clinical Trials & Observations
Sanjal H. Desai,Raphael Mwangi,Wern Lynn Ng,Rebecca L. King,Matthew J. Maurer,James R. Cerhan,Andrew L. Feldman,Umar Farooq,Eric Mou,Thomas M. Habermann,Carrie A. Thompson,Yucai Wang,Thomas E. Witzig,Grzegorz S. Nowakowski
View Articletitled, Increasing tissue requirements in lymphoma trials may exclude patients with high-risk disease or worse prognosis
Supplemental data
The Consortium on Newborn Screening in Africa for sickle cell disease: study rationale and methodology
Clinical Trials & Observations Global Advances
Nancy S. Green,Andrew Zapfel,Obiageli E. Nnodu,Patience Franklin,Venée N. Tubman,Lulu Chirande,Charles Kiyaga,Catherine Chunda-Liyoka,Bernard Awuonda,Kwaku Ohene-Frempong,Baba P. D. Inusa,Russell E. Ware,Isaac Odame,Emmanuela E. Ambrose,Livingstone G. Dogara,Assaf P. Oron,Chase Willett,Alexis A. Thompson,Nancy Berliner,Theresa L. Coetzer,Enrico M. Novelli
View Articletitled, The Consortium on Newborn Screening in Africa for sickle cell disease: study rationale and methodology
Supplemental data

HEALTH SERVICES AND OUTCOMES

Gender and early-career faculty disparities in hematology and oncology board review lecture series
Sebawe Syaj,Leen Al-Kraimeen,Marah Akhdar,Hassan Abushukair,Razan Mohty,Samer Al Hadidi
View Articletitled, Gender and early-career faculty disparities in hematology and oncology board review lecture series

HEMATOPOIESIS AND STEM CELLS

Developmental cues license megakaryocyte priming in murine hematopoietic stem cells
Trine A. Kristiansen,Qinyu Zhang,Stefano Vergani,Elena Boldrin,Niklas Krausse,Oscar André,Pontus Nordenfelt,Mikael Sigvardsson,David Bryder,Jonas Ungerbäck,Joan Yuan
View Articletitled, Developmental cues license megakaryocyte priming in murine hematopoietic stem cells
Supplemental data

IMMUNOBIOLOGY AND IMMUNOTHERAPY

Early cytopenias and infections after standard of care idecabtagene vicleucel in relapsed or refractory multiple myeloma
Jennifer M. Logue,Lauren C. Peres,Hamza Hashmi,Christelle M. Colin-Leitzinger,Alexandria M. Shrewsbury,Hitomi Hosoya,Rebecca M. Gonzalez,Christina Copponex,Krista H. Kottra,Vanna Hovanky,Bita Sahaf,Sunita Patil,Aleksandr Lazaryan,Michael D. Jain,Aliyah Baluch,Olga V. Klinkova,Nelli Bejanyan,Rawan G. Faramand,Hany Elmariah,Farhad Khimani,Marco L. Davila,Asmita Mishra,Brandon J. Blue,Ariel F. Grajales-Cruz,Omar A. Castaneda Puglianini,Hien D. Liu,Taiga Nishihori,Ciara L. Freeman,Jason B. Brayer,Kenneth H. Shain,Rachid C. Baz,Frederick L. Locke,Melissa Alsina,Surbhi Sidana,Doris K. Hansen
View Articletitled, Early cytopenias and infections after standard of care idecabtagene vicleucel in relapsed or refractory multiple myeloma
Supplemental data

LYMPHOID NEOPLASIA

CD47 overexpression is common in intestinal non-GCB type diffuse large B-cell lymphoma and associated with 18q21 gain
Junhun Cho,Sang Eun Yoon,Seok Jin Kim,Young Hyeh Ko,Won Seog Kim
View Articletitled, CD47 overexpression is common in intestinal non-GCB type diffuse large B-cell lymphoma and associated with 18q21 gain
Outcomes of older patients with diffuse large B-cell lymphoma treated with R-CHOP: 10-year follow-up of the LNH03-6B trial
Vincent Camus,Aurélien Belot,Lucie Oberic,David Sibon,Hervé Ghesquières,Catherine Thieblemont,Christophe Fruchart,Olivier Casasnovas,Jean-Marie Michot,Thierry Jo Molina,André Bosly,Clémentine Joubert,Corinne Haioun,Emmanuelle Nicolas-Virelizier,Pierre Feugier,Olivier Fitoussi,Richard Delarue,Hervé Tilly
View Articletitled, Outcomes of older patients with diffuse large B-cell lymphoma treated with R-CHOP: 10-year follow-up of the LNH03-6B trial
Supplemental data

PLATELETS AND THROMBOPOIESIS

Real-world effectiveness of caplacizumab vs the standard of care in immune thrombotic thrombocytopenic purpura
Cristina Pascual Izquierdo,María Eva Mingot-Castellano,Ana E. Kerguelen Fuentes,José García-Arroba Peinado,Joan Cid,Maria Moraima Jimenez,David Valcarcel,Inés Gómez-Seguí,Javier de la Rubia,Paz Martin,Rosa Goterris,Luis Hernández,Inmaculada Tallón,Sara Varea,Marta Fernández,Nadia García-Muñoz,Míriam Vara,Miguel Fernández Zarzoso,Faustino García-Candel,María Liz Paciello,Irene García-García,Saioa Zalba,Verónica Campuzano,José María Gala,Julia Vidán Estévez,Gemma Moreno Jiménez,José Luis López Lorenzo,Elena González Arias,Carmen Freiría,María Solé,Laura Francisca Ávila Idrovo,José Carlos Hernández Castellet,Naylen Cruz,Esperanza Lavilla,Albert Pérez-Montaña,Jon Ander Atucha,María Esperanza Moreno Beltrán,Juán Ramón Moreno Macías,Ramón Salinas,Julio del Rio-Garma,on behalf of Spanish Apheresis Group (GEA) and the Spanish Thrombotic Thrombocytopenic Purpura Registry (REPTT)
View Articletitled, Real-world effectiveness of caplacizumab vs the standard of care in immune thrombotic thrombocytopenic purpura
Supplemental data

RED CELLS, IRON, AND ERYTHROPOIESIS

Evaluation of the combination therapy of hydroxyurea and thalidomide in β-thalassemia
Clinical Trials & Observations Global Advances
Saqib H. Ansari,Iqra Ansari,Misbah Wasim,Amjad Sattar,Shariqa Khawaja,Muhammad Zohaib,Zeeshan Hussain,Syed Omair Adil,Ali H. Ansari,Usman H. Ansari,Fawad Farooq,Noor-un-Nisa Masqati
View Articletitled, Evaluation of the combination therapy of hydroxyurea and thalidomide in β-thalassemia
Incidence of acquired pure red cell aplasia: a nationwide epidemiologic analysis with 2 registry databases in Japan
Hideyuki Nakazawa,Kaoko Sakai,Akiko Ohta,Naohito Fujishima,Akira Matsuda,Kohei Hosokawa,Fumi Nakamura,Shinji Nakao,Kinuko Mitani,Fumihiro Ishida
View Articletitled, Incidence of acquired pure red cell aplasia: a nationwide epidemiologic analysis with 2 registry databases in Japan

THROMBOSIS AND HEMOSTASIS

Surgical outcomes in people with hemophilia A taking emicizumab prophylaxis: experience from the HAVEN 1-4 studies
Rebecca Kruse-Jarres,Flora Peyvandi,Johannes Oldenburg,Tiffany Chang,Sammy Chebon,Michelle Y. Doral,Stacy E. Croteau,Thierry Lambert,Christine L. Kempton,Steven W. Pipe,Richard H. Ko,Benjamin Trzaskoma,Christophe Dhalluin,Nives Selak Bienz,Markus Niggli,Michaela Lehle,Ido Paz-Priel,Guy Young,Víctor Jiménez-Yuste
View Articletitled, Surgical outcomes in people with hemophilia A taking emicizumab prophylaxis: experience from the HAVEN 1-4 studies
Supplemental data
Lymphatic coagulation and neutrophil extracellular traps in lung-draining lymph nodes of COVID-19 decedents
Margo E. MacDonald,Rachel K. Weathered,Emma C. Stewart,Alexandra I. Magold,Anish Mukherjee,Sandeep Gurbuxani,Heather Smith,Phillip McMullen,Jeffrey Mueller,Aliya N. Husain,Calixto M. Salles,Priscilla S. Briquez,Sherin J. Rouhani,Jovian Yu,Jonathan Trujillo,Athalia R. Pyzer,Thomas F. Gajewski,Anne I. Sperling,Witold W. Kilarski,Melody A. Swartz
View Articletitled, Lymphatic coagulation and neutrophil extracellular traps in lung-draining lymph nodes of COVID-19 decedents
Supplemental data
ABO blood group type and risk of venous thromboembolism in patients with cancer
Cornelia Englisch,Florian Moik,Stephan Nopp,Markus Raderer,Ingrid Pabinger,Cihan Ay
View Articletitled, ABO blood group type and risk of venous thromboembolism in patients with cancer
Supplemental data

TRANSPLANTATION

Clinical response to belumosudil in bronchiolitis obliterans syndrome: a combined analysis from 2 prospective trials
Clinical Trials & Observations
Zachariah DeFilipp,Haesook T. Kim,Zhongming Yang,John Noonan,Bruce R. Blazar,Stephanie J. Lee,Steven Z. Pavletic,Corey Cutler
View Articletitled, Clinical response to belumosudil in bronchiolitis obliterans syndrome: a combined analysis from 2 prospective trials
Supplemental data
Extended-duration letermovir prophylaxis for cytomegalovirus infection after cord blood transplantation in adults
Ioannis Politikos,Carmen Lau,Sean M. Devlin,Sean Quach,Andrew Lin,Miguel-Angel Perales,Gunjan L. Shah,Susan K. Seo,Genovefa A. Papanicolaou,Juliet N. Barker
View Articletitled, Extended-duration letermovir prophylaxis for cytomegalovirus infection after cord blood transplantation in adults

RESEARCH LETTERS

Clofarabine treatment of KMT2Ar infantile patients with acute lymphoblastic leukemia in St. Jude Total Therapy Study 16
Clinical Trials & Observations
Tanja A. Gruber,Deqing Pei,John Choi,Cheng Cheng,Elaine Coustan-Smith,Dario Campana,Hope D. Swanson,Jennifer L. Pauley,Hiroto Inaba,Monika L. Metzger,Jeffrey E. Rubnitz,Raul C. Ribeiro,Susana C. Raimondi,Ching-Hon Pui,Sima Jeha
View Articletitled, Clofarabine treatment of <em>KMT2A</em>r infantile patients with acute lymphoblastic leukemia in St. Jude Total Therapy Study 16
Supplemental data
The need for rapid cytogenetics in the era of unique therapies for acute myeloid leukemia
Anjanaa Vijayanarayanan,Brandon M. Shaw,Kathryn Gibbons,Kedar V. Inamdar,Philip Kuriakose,Madhu P. Menon
View Articletitled, The need for rapid cytogenetics in the era of unique therapies for acute myeloid leukemia

ERRATA

Elbracht M, Meyer R, Kricheldorf K, et al. Germline variants in DNA repair genes, including BRCA1/2, may cause familial myeloproliferative neoplasms. Blood Adv. 2021;5(17):3373-3376.
View Articletitled, Elbracht M, Meyer R, Kricheldorf K, et al. Germline variants in DNA repair genes, including <em>BRCA1/2</em>, may cause familial myeloproliferative neoplasms. <em>Blood Adv.</em> 2021;5(17):3373-3376.
Kudo K, Kubota Y, Toki T, et al. Childhood acute myeloid leukemia with 5q deletion and HNRNPH1-MLLT10 fusion: the first case report. Blood Adv. 2022;6(10):3162-3166.
View Articletitled, Kudo K, Kubota Y, Toki T, et al. Childhood acute myeloid leukemia with 5q deletion and <em>HNRNPH1-MLLT10</em> fusion: the first case report. <em>Blood Adv</em>. 2022;6(10):3162-3166.
  • Cover Image

    Cover Image

    issue cover
    Ectopic release of (pro)platelet-like particles in the bone marrow of ARPC2-deficient mice. Cryosections were stained for glycoprotein IX (cyan) to visualize megakaryocytes and (pro)platelet-like particles and CD105 (red) to identify sinusoids. See the article by Bender et al.
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