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Issue Archive

Volume 3, Issue 12
June 25 2019
Blood Advances Cover Image for Volume 3, Issue 12

Table of Contents

BLOOD ADVANCES TALK

Managing patients who are receiving warfarin or a direct oral anticoagulant and need an elective surgery or procedure
James Douketis,Andrea Cervi
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DRUG ADVANCES

Romiplostim for the management of pediatric immune thrombocytopenia: drug development and current practice
Clinical Trials & Observations
Cindy E. Neunert,Melissa J. Rose
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EXCEPTIONAL CASE REPORTS

B-cell acute lymphoblastic leukemia with high mutation burden presenting in a child with constitutional mismatch repair deficiency
Clinical Trials & Observations
Benjamin Oshrine,Nanette Grana,Colin Moore,Johnny Nguyen,Melissa Crenshaw,Melissa Edwards,Sumedha Sudhaman,Victoria J. Forster,Uri Tabori
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BRAF-V600E–mutated Rosai-Dorfman-Destombes disease and Langerhans cell histiocytosis with response to BRAF inhibitor
Clinical Trials & Observations
Rosemarie Mastropolo,Allison Close,Steven W. Allen,Kenneth L. McClain,Scott Maurer,Jennifer Picarsic
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Myoclonic jerks complicating treatment of acute promyelocytic leukemia: case report and literature review
Clinical Trials & Observations
John Y. Rhee,Douglas Tremblay,Amy M. Chan,Martin S. Tallman,John Mascarenhas
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STIMULUS REPORTS

CRISPR genome editing of murine hematopoietic stem cells to create Npm1-Alk causes ALK+ lymphoma after transplantation
Soumya Sundara Rajan,Lingxiao Li,Mercedes F. Kweh,Kranthi Kunkalla,Amit Dipak Amin,Nitin K. Agarwal,Francisco Vega,Jonathan H. Schatz
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Inhibition of EZH2 and immune signaling exerts synergistic antitumor effects in chronic lymphocytic leukemia
Elisavet Chartomatsidou,Stavroula Ntoufa,Konstantia Kotta,Alessandra Rovida,Maria Anna Akritidou,Daniela Belloni,Elisabetta Ferrero,Theoni Trangas,Niki Stavroyianni,Achilles Anagnostopoulos,Richard Rosenquist,Paolo Ghia,Nikos Papakonstantinou,Kostas Stamatopoulos
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REVIEW ARTICLE

In vivo dynamics of human hematopoietic stem cells: novel concepts and future directions
Serena Scala,Alessandro Aiuti
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CLINICAL TRIALS AND OBSERVATIONS

Long-term safety of single-agent ibrutinib in patients with chronic lymphocytic leukemia in 3 pivotal studies
Clinical Trials & Observations
Steven E. Coutre,John C. Byrd,Peter Hillmen,Jacqueline C. Barrientos,Paul M. Barr,Stephen Devereux,Tadeusz Robak,Thomas J. Kipps,Anna Schuh,Carol Moreno,Richard R. Furman,Jan A. Burger,Michael O’Dwyer,Paolo Ghia,Rudolph Valentino,Stephen Chang,James P. Dean,Danelle F. James,Susan M. O’Brien
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CyBorD-DARA is potent initial induction for MM and enhances ADCP: initial results of the 16-BCNI-001/CTRIAL-IE 16-02 study
Clinical Trials & Observations
M. O’Dwyer,R. Henderson,S. D. Naicker,M. R. Cahill,P. Murphy,V. Mykytiv,J. Quinn,C. McEllistrim,J. Krawczyk,J. Walsh,E. Lenihan,T. Kenny,A. Hernando,G. Hirakata,I. Parker,E. Kinsella,G. Gannon,A. Natoni,K. Lynch,A. E. Ryan
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IMMUNOBIOLOGY AND IMMUNOTHERAPY

Absence of complement component 3 does not prevent classical pathway–mediated hemolysis
Lingjun Zhang,Yang Dai,Ping Huang,Thomas L. Saunders,David A. Fox,Jijun Xu,Feng Lin
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MYELOID NEOPLASIA

A genomics-informed computational biology platform prospectively predicts treatment responses in AML and MDS patients
Clinical Trials & Observations
Leylah M. Drusbosky,Neeraj Kumar Singh,Kimberly E. Hawkins,Cesia Salan,Madeleine Turcotte,Elizabeth A. Wise,Amy Meacham,Vindhya Vijay,Glenda G. Anderson,Charlie C. Kim,Saumya Radhakrishnan,Yashaswini Ullal,Anay Talawdekar,Huzaifa Sikora,Prashant Nair,Arati Khanna-Gupta,Taher Abbasi,Shireen Vali,Subharup Guha,Nosha Farhadfar,Hemant S. Murthy,Biljana N. Horn,Helen L. Leather,Paul Castillo,Caitlin Tucker,Christina Cline,Leslie Pettiford,Jatinder K. Lamba,Jan S. Moreb,Randy A. Brown,Maxim Norkin,John W. Hiemenz,Jack W. Hsu,William B. Slayton,John R. Wingard,Christopher R. Cogle
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SYSTEMATIC REVIEW

Defining autoimmune hemolytic anemia: a systematic review of the terminology used for diagnosis and treatment
Quentin A. Hill,Anita Hill,Sigbjørn Berentsen
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THROMBOSIS AND HEMOSTASIS

Tumor microenvironment and clonal monocytes from chronic myelomonocytic leukemia induce a procoagulant climate
Johanna Zannoni,Natacha Mauz,Landry Seyve,Mathieu Meunier,Karin Pernet-Gallay,Julie Brault,Claire Jouzier,David Laurin,Mylène Pezet,Martine Pernollet,Jean-Yves Cahn,Fabrice Cognasse,Benoît Polack,Sophie Park
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TRANSPLANTATION

Outcomes of haploidentical vs matched sibling transplantation for acute myeloid leukemia in first complete remission
Clinical Trials & Observations
Armin Rashidi,Mehdi Hamadani,Mei-Jie Zhang,Hai-Lin Wang,Hisham Abdel-Azim,Mahmoud Aljurf,Amer Assal,Ashish Bajel,Asad Bashey,Minoo Battiwalla,Amer M. Beitinjaneh,Nelli Bejanyan,Vijaya Raj Bhatt,Javier Bolaños-Meade,Michael Byrne,Jean-Yves Cahn,Mitchell Cairo,Stefan Ciurea,Edward Copelan,Corey Cutler,Andrew Daly,Miguel-Angel Diaz,Nosha Farhadfar,Robert P. Gale,Siddhartha Ganguly,Michael R. Grunwald,Theresa Hahn,Shahrukh Hashmi,Gerhard C. Hildebrandt,H. Kent Holland,Nasheed Hossain,Christopher G. Kanakry,Mohamed A. Kharfan-Dabaja,Nandita Khera,Yener Koc,Hillard M. Lazarus,Jong-Wook Lee,Johan Maertens,Rodrigo Martino,Joseph McGuirk,Reinhold Munker,Hemant S. Murthy,Ryotaro Nakamura,Sunita Nathan,Taiga Nishihori,Neil Palmisiano,Sagar Patel,Joseph Pidala,Rebecca Olin,Richard F. Olsson,Betul Oran,Olov Ringden,David Rizzieri,Jacob Rowe,Mary Lynn Savoie,Kirk R. Schultz,Sachiko Seo,Brian C. Shaffer,Anurag Singh,Melhem Solh,Keith Stockerl-Goldstein,Leo F. Verdonck,John Wagner,Edmund K. Waller,Marcos De Lima,Brenda M. Sandmaier,Mark Litzow,Dan Weisdorf,Rizwan Romee,Wael Saber
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Haploidentical vs haplo-cord transplant in adults under 60 years receiving fludarabine and melphalan conditioning
Clinical Trials & Observations
Koen van Besien,Andrew Artz,Richard E. Champlin,Danielle Guarneri,Michael R. Bishop,Julianne Chen,Usama Gergis,Tsiporah Shore,Hongtao Liu,Gabriela Rondon,Sebastian A. Mayer,Samer A. Srour,Wendy Stock,Stefan O. Ciurea
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External validation and comparison of multiple prognostic scores in allogeneic hematopoietic stem cell transplantation
Clinical Trials & Observations
Roni Shouval,Joshua A. Fein,Aniela Shouval,Ivetta Danylesko,Noga Shem-Tov,Maya Zlotnik,Ronit Yerushalmi,Avichai Shimoni,Arnon Nagler
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All Issues

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Overcoming venetoclax resistance through heme-mediated NOXA/cyclin D1/Mcl-1 axis with a novel artemisinin conjugate

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