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Journal Articles

The Role and Therapeutic Target of Base Excision Repair Genes in Multiple Myeloma (MM)

Rumi Ino, Takayuki Saitoh, MD PhDProf, Yuya Kitamura, Kazuki Homma, Noriyuki Takahashi, Gotoh Nanami, Master, Tetsuhiro Kasamatsu, PhD, Hiroaki Shimizu, MD PhD, Makiko Takizawa, PhDMD, Morio Matsumoto, MD, Morio Sawamura, MD PhD, Akihiko Yokohama, MD PhD, Norifumi Tsukamoto, MDPhDChief Division, Hiroshi Handa, MD PhDChief Division, Hirokazu Murakami, MDPhDProf

Blood (2017) 130 (Supplement 1): 4403.

https://doi.org/10.1182/blood.V130.Suppl_1.4403.4403

Published: 2017

Journal Articles

Proteomic Profiling Identifies c-KIT and 53BP1 As Resistance Factors of AML Relapse Post Allogeneic Stem Cell Transplantation with G-CSF/Plerixafor/Busulfan-Fludarabine Conditioning

Zhihong Zeng, MD, Hongbo Lu, MD, Rui-Yu Wang, MD, Wenbin Lu, PhD, Julianne Chen, Christopher B Benton, MD, Keith Baggerly, PhD, Elizabeth J Shpall, MD, Richard E Champlin, MD, Marina Konopleva, MD PhD, Michael Andreeff, MD PhD

Blood (2017) 130 (Supplement 1): 2528.

https://doi.org/10.1182/blood.V130.Suppl_1.2528.2528

Published: 2017

Journal Articles

Concurrent Treatment with Pim Kinase Inhibitor Downregulates Alternative Non-Homologous End-Joining Repair and Decreases Genomic Instability in FLT3-ITD Cells Treated with Topoisomerase 2 Inhibitor Chemotherapy Drugs

Kshama A. Doshi, PhD, Shivani Kapoor, MS, Ying Zou, MD PhD, Xiang Li, PhD, Mario Scarpa, MS, Nidal Muvarak, PhD, Pratik Nagaria, PhD, Olga Goloubeva, PhD MSc, Adriana E. Tron, PhD, Charles J. Bieberich, PhD, Feyruz V. Rassool, BSc, PhD, Maria R. Baer, MD

Blood (2017) 130 (Supplement 1): 1243.

https://doi.org/10.1182/blood.V130.Suppl_1.1243.1243

Published: 2017

Journal Articles

Chromatin Histone Modifying and DNA Repair Inhibition Enhances the Anti-Myeloma Activity of Melphalan

Maria Gkotzamanidou, Evangelos Terpos, Nikhil C Munshi, MD, Vassilis L. Souliotis, Meletios A Dimopoulos

Blood (2016) 128 (22): 4437.

https://doi.org/10.1182/blood.V128.22.4437.4437

Published: 2016

Journal Articles

Base Excision Repair Gene OGG1 Affects the Relapse Risk of Acute Myeloid Leukemia

Nanami Gotoh, Takayuki Saitoh, MD PhD, Noriyuki Takahashi, Rumi Ino, Yuya Kitamura, Kazuki Honma, Tomomi Nagashima, Tetsuhiro Kasamatsu, Takumi Hoshino, MD, Toru Sakura, MD, Makiko Takizawa, Ph DMD, Akihiko Yokohama, MD PhD, Hiroaki Shimizu, MD PhD, Hiroshi Handa, MD PhD, Norifumi Tsukamoto, MD PhD, Hirokazu Murakami, MD PhD

Blood (2016) 128 (22): 2901.

https://doi.org/10.1182/blood.V128.22.2901.2901

Published: 2016

Journal Articles

Prognostic Impact of TS, MTHFR and XRCC1 Genetic Variants in 113 Patients with Myelodysplastic Syndromes

Blood (2015) 126 (23): 1675.

https://doi.org/10.1182/blood.V126.23.1675.1675

Published: 2015

Journal Articles

Genetic Variations in Calicheamicin Pathway Genes Are Predictors of Gemtuzumab Ozogamicin Response in AML Patients: Results from COG-AAML0531 Study

Jatinder K Lamba, PhD, Lata Chauhan, PhD, Richard Aplenc, MD PhD, Maggie Skrypek, MD, Jessica Pollard, MD, Todd A. Alonzo, PhD, Y-C Wang, Irwin D. Bernstein, MD, Alan S. Gamis, MD MPH, Soheil Meshinchi, MD PhD

Blood (2015) 126 (23): 1260.

https://doi.org/10.1182/blood.V126.23.1260.1260

Published: 2015

Journal Articles

The State of Chromatin Condensation, the Expression of Genes Involved in DNA Damage Response and the DNA Repair Capacity Affect the Drug Sensitivity of PBMCs of Myeloma Patients Treated with Melphalan

Maria Gkotzamanidou, Evangelos Terpos, Nikhil C. Munshi, MD, Vassilis L. Souliotis, Meletios A. Dimopoulos

Blood (2015) 126 (23): 3628.

https://doi.org/10.1182/blood.V126.23.3628.3628

Published: 2015

Journal Articles

Microrna Expression and Drug-Induced Changes in Gene Expression Correlate with Ara-C Chemosensitivity in AML Cell Lines

Neha S Bhise, Vishal Lamba, PhD, Jatinder Lamba, PhD

Blood (2014) 124 (21): 3623.

https://doi.org/10.1182/blood.V124.21.3623.3623

Published: 2014

Journal Articles

High-Throughput, High-Content siRNA/Drug Modifier Screen for Validation of Transcriptional Profiles Predictive of Cytarabine Response in AML

Jatinder Lamba, PhD, Lata Chauhan, PhD, Christophe Echeverri, PhD, Kerstin Korn, Kartini Kochar, Xueyuan Cao, PhD, Stanley Pounds, PhD

Blood (2014) 124 (21): 3615.

https://doi.org/10.1182/blood.V124.21.3615.3615

Published: 2014

Journal Articles

Targeting components of the alternative NHEJ pathway sensitizes KRAS mutant leukemic cells to chemotherapy

Patricia S. Hähnel, Birgit Enders, Daniel Sasca, Wynand P. Roos, Bernd Kaina, Lars Bullinger, Matthias Theobald, Thomas Kindler

Blood (2014) 123 (15): 2355–2366.

https://doi.org/10.1182/blood-2013-01-477620

Published: 2014

Includes: Supplemental data

Journal Articles

The Polymorphism Of Base Excision Repair Gene, XRCC1 Arg399Gln Is Associated With The Therapy-Related Myelodysplastic Syndromes (MDS)

Batchimeg Norjmaa, Takayuki Saitoh, M.D. Ph.D., Atsushi Iwasaki, Yasuhiro Nitta, Yuta Masuda, Itsumi Suda, Ayaka Kaneko, Hiroaki Shimizu, M.D.Ph.D., Hiroshi Handa, MD, PhD, Akihiko Yokohama, MD, PhD, Norifumi Tsukamoto, MD, PhD, Toru Sakura, MD, PhD, Hirokazu Murakami, M.D.Ph.D.

Blood (2013) 122 (21): 4085.

https://doi.org/10.1182/blood.V122.21.4085.4085

Published: 2013

Journal Articles

The Polymorphisms Of Base Excision Repair Genes Influence The Cytogenetic Risk Factors In Acute Myeloid Leukemia

Atsushi Iwasaki, Takayuki Saitoh, M.D. Ph.D., Yasuhiro Nitta, Batchimeg Norjimaa, Chiharu Omiya, Akira Kamiya, Nahoko Hatsumi, M.D., Hiroaki Shimizu, M.D. Ph.D., Takuma Ishizaki, M.D. Ph.D., Takumi Hoshino, Satoru Takada, MD, Hiroshi Handa, MD, PhD, Toru Sakura, MD, PhD, Akihiko Yokohama, MD, PhD, Norifumi Tsukamoto, MD, PhD, Hirokazu Murakami, M.D. Ph.D.

Blood (2013) 122 (21): 1355.

https://doi.org/10.1182/blood.V122.21.1355.1355

Published: 2013

Journal Articles

The Mutational Status Of Genes Involved In DNA Repair and Folate Pathway Predicts Overall Survival Of Patients With Low-Risk, Untreated Myelodysplastic Syndrome

Alessandro Isidori, MD, PhD, Annamaria Ruzzo, PhD, Federica Loscocco, Maria Teresa Voso, M.D., Francesco Graziano, Sara Barulli, Emanuele Canestrari, Antonio Volpe, MD, Domenico Magro, MD, Pier Paolo Piccaluga, MD, PhD, Fabio Fuligni, Stefania Paolini, Teresa Ricciardi, Paola Picardi, Elisa Giacomini, Marco Rocchi, Mauro Magnani, Giuseppe Visani, MD

Blood (2013) 122 (21): 2815.

https://doi.org/10.1182/blood.V122.21.2815.2815

Published: 2013

Journal Articles

The Polymorphisms of Base Excision Repair Genes Influence the Prognosis of Multiple Myeloma

Chiaki Ushie, Takayuki Saitoh, M.D. Ph.D., Atsushi Iwasaki, Norihiko Moriyama, Hikaru Hattori, Morio Matsumoto, MD, Morio Sawamura, M.D. Ph.D., Jun Isoda, M.D. Ph.D., Hiroshi Handa, M.D. Ph.D., Akihiko Yokohama, MD, PhD, Norifumi Tsukamoto, MD, PhD, Hatsue Ogawara, Ph.D., Hirokazu Murakami, M.D., Ph.D.

Blood (2012) 120 (21): 3981.

https://doi.org/10.1182/blood.V120.21.3981.3981

Published: 2012

Journal Articles

Impact of Single Nucleotide Polymorphisms in Genes Involved in DNA Repair and Drug Metabolism On Survival After Autologous Stem Cell Transplantation in Patients with Multiple Myeloma.

Carlos Fernández de Larrea, Alfons Navarro, PhD, Natalia Tovar, Fabiola Pedrosa, Tania Díaz, PhD, María Teresa Cibeira, Laura Magnano, Laura Rosiñol, MD, Montserrat Rovira, María Rozman, Mariano Monzó, MD, PhD, Joan Blade, MD

Blood (2012) 120 (21): 2934.

https://doi.org/10.1182/blood.V120.21.2934.2934

Published: 2012

Journal Articles

The Genotype of MLH1 Is An Independent Predictor of Outcome In Diffuse Large B-Cell Lymphoma Treated with R-CHOP: a Training-Validation Study

Blood (2010) 116 (21): 992.

https://doi.org/10.1182/blood.V116.21.992.992

Published: 2010

Journal Articles

Impact on Response and Survival of DNA Repair Single Nucleotide Polymorphisms In Relapsed or Refractory Multiple Myeloma Patients Treated with Thalidomide

Carlos Fernández de Larrea, María Teresa Cibeira, Alfons Navarro, Tania Díaz, Dolors Fuster, Natalia Tovar, Laura Rosiñol, Mariano Monzó, Joan Blade

Blood (2010) 116 (21): 4041.

https://doi.org/10.1182/blood.V116.21.4041.4041

Published: 2010

Journal Articles

Clinical Significance of Polymorphisms During Hepatopoietic Stem Cell Transplantation.

Jae-Sook Ahn, Hee Nam Kim, Nan Young Kim, Yu– Li, Il-Kwon Lee, Yeo-Kyeoung Kim, Soo-Young Bae, Deok-Hwan Yang, Je-Jung Lee, Hyeoung Joon Kim, MD, PhD

Blood (2010) 116 (21): 3497.

https://doi.org/10.1182/blood.V116.21.3497.3497

Published: 2010

Journal Articles

Prognostic Impact of DNA Repair and MDR-1 Gene Polymorphisms In De Novo Acute Myeloid Leukemia with t(8;21) or Inv(16)

Yeo-Kyeoung Kim, Soo-Young Bae, Hee Nam Kim, Nan Young Kim, Hee-Je Kim, Soo-Mee Bang, Deog-Yeon Jo, Jong-Ho Won, Na-Ri Lee, Jae-Yong Kwak, Jae-Sook Ahn, Deok-Hwan Yang, Il-Kwon Lee, Je-Jung Lee, Hyeoung Joon Kim

Blood (2010) 116 (21): 1714.

https://doi.org/10.1182/blood.V116.21.1714.1714

Published: 2010

NARROW

The Role and Therapeutic Target of Base Excision Repair Genes in Multiple Myeloma (MM)

Proteomic Profiling Identifies c-KIT and 53BP1 As Resistance Factors of AML Relapse Post Allogeneic Stem Cell Transplantation with G-CSF/Plerixafor/Busulfan-Fludarabine Conditioning

Concurrent Treatment with Pim Kinase Inhibitor Downregulates Alternative Non-Homologous End-Joining Repair and Decreases Genomic Instability in FLT3-ITD Cells Treated with Topoisomerase 2 Inhibitor Chemotherapy Drugs

Chromatin Histone Modifying and DNA Repair Inhibition Enhances the Anti-Myeloma Activity of Melphalan

Base Excision Repair Gene OGG1 Affects the Relapse Risk of Acute Myeloid Leukemia

Prognostic Impact of TS, MTHFR and XRCC1 Genetic Variants in 113 Patients with Myelodysplastic Syndromes

Genetic Variations in Calicheamicin Pathway Genes Are Predictors of Gemtuzumab Ozogamicin Response in AML Patients: Results from COG-AAML0531 Study

The State of Chromatin Condensation, the Expression of Genes Involved in DNA Damage Response and the DNA Repair Capacity Affect the Drug Sensitivity of PBMCs of Myeloma Patients Treated with Melphalan

Microrna Expression and Drug-Induced Changes in Gene Expression Correlate with Ara-C Chemosensitivity in AML Cell Lines

High-Throughput, High-Content siRNA/Drug Modifier Screen for Validation of Transcriptional Profiles Predictive of Cytarabine Response in AML

Targeting components of the alternative NHEJ pathway sensitizes KRAS mutant leukemic cells to chemotherapy

The Polymorphism Of Base Excision Repair Gene, XRCC1 Arg399Gln Is Associated With The Therapy-Related Myelodysplastic Syndromes (MDS)

The Polymorphisms Of Base Excision Repair Genes Influence The Cytogenetic Risk Factors In Acute Myeloid Leukemia

The Mutational Status Of Genes Involved In DNA Repair and Folate Pathway Predicts Overall Survival Of Patients With Low-Risk, Untreated Myelodysplastic Syndrome

The Polymorphisms of Base Excision Repair Genes Influence the Prognosis of Multiple Myeloma

Impact of Single Nucleotide Polymorphisms in Genes Involved in DNA Repair and Drug Metabolism On Survival After Autologous Stem Cell Transplantation in Patients with Multiple Myeloma.

The Genotype of MLH1 Is An Independent Predictor of Outcome In Diffuse Large B-Cell Lymphoma Treated with R-CHOP: a Training-Validation Study

Impact on Response and Survival of DNA Repair Single Nucleotide Polymorphisms In Relapsed or Refractory Multiple Myeloma Patients Treated with Thalidomide

Clinical Significance of Polymorphisms During Hepatopoietic Stem Cell Transplantation.

Prognostic Impact of DNA Repair and MDR-1 Gene Polymorphisms In De Novo Acute Myeloid Leukemia with t(8;21) or Inv(16)

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American Society of Hematology

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American Society of Hematology

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