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Journal Articles

What is going on between defibrotide and endothelial cells? Snapshots reveal the hot spots of their romance

Marta Palomo, Enrique Mir, Montse Rovira, Ginés Escolar, Enric Carreras, Maribel Diaz-Ricart

Blood (2016) 127 (13): 1719–1727.

https://doi.org/10.1182/blood-2015-10-676114

Published: 2016

Includes: Multimedia, Supplemental data

Journal Articles

Synergistic Targeting of Protein Translation and Inhibition of NOTCH Signaling in T-ALL

Marta Sanchez-Martin, PhD, Alberto Ambesi-Impiombato, MDPhD, Luyao Xu, Yue Qin, Daniel Herranz, PhD, Mukesh Bansal, PhD, Tiziana Girardi, Kim De Keersmaecker, Andrea Califano, PhD, Adolfo A. Ferrando, MD PhD

Blood (2015) 126 (23): 3719.

https://doi.org/10.1182/blood.V126.23.3719.3719

Published: 2015

Journal Articles

High Throughput Flow Screening Assays to Profile Cell-Mediated Killing

Kim Yen Luu, PhD, Thomas D Duensing, PhD

Blood (2015) 126 (23): 4629.

https://doi.org/10.1182/blood.V126.23.4629.4629

Published: 2015

Journal Articles

LAT2, a Lipid Raft Protein That Participates in AKT Phosphorylation in Mantle Cell Lymphoma, Is a Target for Perifosine Chemotherapy

Germano A Ferreira, PhD, Carolina H Thomé, PhD, Priscila Santos Scheucher, PhD, Andréia M Leopoldino, Prof. PhD, Ana Maria Simão, PhD, Clarice Izumi, PhD, Pietro Ciancaglini, Prof. PhD, Vitor Marcel Faça, Prof, PhD, Lewis Joel Greene, Prof. PhD, Guilherme A Santos, MD PhD, Eduardo M Rego, Prof, MD PhD

Blood (2014) 124 (21): 923.

https://doi.org/10.1182/blood.V124.21.923.923

Published: 2014

Journal Articles

Presepsin (soluble CD14 subtype) Is Secreted from Human Monocytes after Phagocytosis – in Vitro Analyses and a Retrospective Cohort Study in Patients with Allogeneic Stem Cell Transplantation

Yasuyuki Arai, MD, Kouhei Yamashita, MD PhD, Kiyomi Mizugishi, MD PhD, Akifumi Takaori-Kondo, MD, PhD

Blood (2014) 124 (21): 1402.

https://doi.org/10.1182/blood.V124.21.1402.1402

Published: 2014

Journal Articles

ASK1, a Novel Regulator of Thrombosis, Is Activated Downstream of G-Protein Coupled receptors in Human Platelets

Randall Derstine, MS, Meghna Ulhas Naik, MS, Ramya Turaga, PhD, Ulhas P Naik, PhD FAHA

Blood (2014) 124 (21): 4163.

https://doi.org/10.1182/blood.V124.21.4163.4163

Published: 2014

Journal Articles

Heme Potently Stimulates Tissue Factor Expression By Peripheral Blood Monocytes: A Novel Mechanism For Thrombosis In Intravascular Hemolytic Diseases

Teena Rehani, Ph.D., Kristin Mathson, B.S., John D Belcher, Ph.D., Gregory M Vercellotti, Arne Slungaard, MD

Blood (2013) 122 (21): 2215.

https://doi.org/10.1182/blood.V122.21.2215.2215

Published: 2013

Journal Articles

PI3K/AKT/mTOR Signaling Is a Significant Druggable Pathway In Infant Acute Lymphoblastic Leukemia (ALL)

Karen A. Urtishak, PhD, Wang Li-San, PhD, David T. Teachey, MD, Tasian K. Sarah, MD, Jeffrey S. Barrett, PhD, I-Ming L. Chen, Susan R. Atlas, PhD, Richard C. Harvey, PhD, Nyla A. Heerema, PhD, Andrew J. Carroll, PhD, Stephen P. Hunger, MD, Cheryl L. Willman, MD, Carolyn A. Felix, MD

Blood (2013) 122 (21): 1669.

https://doi.org/10.1182/blood.V122.21.1669.1669

Published: 2013

Journal Articles

Both PI3K p110α and p110δ Isoforms Control CD160-Mediated CLL Cell Viability and Cytokine Production

Timothy W. Farren, Ph.D, Fengting Liu, MD Ph.D, Samir G. Agrawal

Blood (2013) 122 (21): 4124.

https://doi.org/10.1182/blood.V122.21.4124.4124

Published: 2013

Journal Articles

Rhog Regulates GPVI/FcRγ-Mediated Platelet Activation and Thrombus Formation

Soochong Kim, DVM, PhD, Carol Dangelmaier, Dheeraj Bhavanasi, Shu Meng, Hong Wang, MD, PhD, Lawrence E Goldfinger, Satya P. Kunapuli, PhD

Blood (2013) 122 (21): 1060.

https://doi.org/10.1182/blood.V122.21.1060.1060

Published: 2013

Journal Articles

PAK and Akt Interactions Regulate PAR-Mediated Akt Translocation to Membrane in Platelets: A Novel PIP3-Independent Mechanism.

Rachit Badolia

Blood (2012) 120 (21): 2166.

https://doi.org/10.1182/blood.V120.21.2166.2166

Published: 2012

Journal Articles

Axl Receptor Tyrosine Kinase Signaling Pathway and the p53 Tumor Suppressor Protein Exist In A Novel Regulatory Loop In B-Cell Chronic Lymphocytic Leukemia Cells

Asish K Ghosh, PhD, Justin Boysen, Tammy Price-troska, Charla Secreto, Clive S. Zent, MD, Neil Kay, MD

Blood (2011) 118 (21): 799.

https://doi.org/10.1182/blood.V118.21.799.799

Published: 2011

Journal Articles

Linker of Activation of T Cells – 2 (LAT2), a Lipid Raft-Associated Adaptor Protein, Is a Novel Target for Therapy in Acute Leukemia

Guilherme A dos Santos, Carolina H Thomé, Germano Aguiar Ferreira, Priscila S Scheucher, Ph.D, Antonio R Lucena-Araujo, Kleber T de Oliveira, Hamilton L. Gimenes-Teixeira, Ph.D, Pietro Ciancaglini, Roberto P. Falcao, M.D., Ph.D, Lewis J Greene, Faça M Vitor, Eduardo M. Rego, M.D., Ph.D

Blood (2011) 118 (21): 737.

https://doi.org/10.1182/blood.V118.21.737.737

Published: 2011

Journal Articles

A Lymphoma-Associated Mutation in BAFF-R Drives Constitutive PI3K Signaling and Increased Expression of Pro-Survival Genes

Frank J Secreto, Michelle K Manske, Tammy Price-Troska, Steven C. Ziesmer, Stephen M Ansell, MD, James R Cerhan, MD, PhD, Anne J. Novak, Ph.D.

Blood (2011) 118 (21): 2642.

https://doi.org/10.1182/blood.V118.21.2642.2642

Published: 2011

Journal Articles

Tissue Factor Is Internalized by Platelets Through Activation of RhoA and PI 3 -Kinase Promoting Reversible Cytoskeletal Assembly,

Gines Escolar, MD, PhD, Irene Lopez-Vilchez, Ph.D., Ana M Galan, Ph.D., Merce Roque, M.D., Ph.D., James G White, Regents, Professor, Maribel Diaz-Ricart, PhD

Blood (2011) 118 (21): 3264.

https://doi.org/10.1182/blood.V118.21.3264.3264

Published: 2011

Journal Articles

The Role of Akt3 in Mediating Outside-in Signaling of the Platelet Integrin αIIbβ3

Kelly A O'Brien, Nissim Hay, PhD, Xiaoping Du, MD, PhD

Blood (2011) 118 (21): 1134.

https://doi.org/10.1182/blood.V118.21.1134.1134

Published: 2011

Journal Articles

Genomic and Pathway Connectivity Analyses Identify Novel Strategies to Overcome mTOR Inhibitor Resistance In DLBCL

Adam M. Petrich, MD, Violetta V. Leshchenko, PhD, Pei-Yu Kuo, MS, B. Hilda Ye, PhD, Joseph A Sparano, MD, Samir Parekh, MD

Blood (2010) 116 (21): 436.

https://doi.org/10.1182/blood.V116.21.436.436

Published: 2010

Journal Articles

Reconstitution of PTEN activity by CK2 inhibitors and interference with the PI3-K/Akt cascade counteract the antiapoptotic effect of human stromal cells in chronic lymphocytic leukemia

Medhat Shehata, Susanne Schnabl, Dita Demirtas, Martin Hilgarth, Rainer Hubmann, Elena Ponath, Sigrun Badrnya, Claudia Lehner, Andrea Hoelbl, Markus Duechler, Alexander Gaiger, Christoph Zielinski, Josef D. Schwarzmeier, Ulrich Jaeger

Blood (2010) 116 (14): 2513–2521.

https://doi.org/10.1182/blood-2009-10-248054

Published: 2010

Includes: Supplemental data

Journal Articles

Factor XII stimulates ERK1/2 and Akt through uPAR, integrins, and the EGFR to initiate angiogenesis

Gretchen A. LaRusch, Fakhri Mahdi, Zia Shariat-Madar, Gregory Adams, Robert G. Sitrin, Wan Ming Zhang, Keith R. McCrae, Alvin H. Schmaier

Blood (2010) 115 (24): 5111–5120.

https://doi.org/10.1182/blood-2009-08-236430

Published: 2010

Includes: Supplemental data

Journal Articles

PfPI3K, a phosphatidylinositol-3 kinase from Plasmodium falciparum , is exported to the host erythrocyte and is involved in hemoglobin trafficking

Ankush Vaid, Ravikant Ranjan, Wynand A. Smythe, Heinrich C. Hoppe, Pushkar Sharma

Blood (2010) 115 (12): 2500–2507.

https://doi.org/10.1182/blood-2009-08-238972

Published: 2010

Includes: Supplemental data

NARROW

What is going on between defibrotide and endothelial cells? Snapshots reveal the hot spots of their romance

Synergistic Targeting of Protein Translation and Inhibition of NOTCH Signaling in T-ALL

High Throughput Flow Screening Assays to Profile Cell-Mediated Killing

LAT2, a Lipid Raft Protein That Participates in AKT Phosphorylation in Mantle Cell Lymphoma, Is a Target for Perifosine Chemotherapy

Presepsin (soluble CD14 subtype) Is Secreted from Human Monocytes after Phagocytosis – in Vitro Analyses and a Retrospective Cohort Study in Patients with Allogeneic Stem Cell Transplantation

ASK1, a Novel Regulator of Thrombosis, Is Activated Downstream of G-Protein Coupled receptors in Human Platelets

Heme Potently Stimulates Tissue Factor Expression By Peripheral Blood Monocytes: A Novel Mechanism For Thrombosis In Intravascular Hemolytic Diseases

PI3K/AKT/mTOR Signaling Is a Significant Druggable Pathway In Infant Acute Lymphoblastic Leukemia (ALL)

Both PI3K p110α and p110δ Isoforms Control CD160-Mediated CLL Cell Viability and Cytokine Production

Rhog Regulates GPVI/FcRγ-Mediated Platelet Activation and Thrombus Formation

PAK and Akt Interactions Regulate PAR-Mediated Akt Translocation to Membrane in Platelets: A Novel PIP3-Independent Mechanism.

Axl Receptor Tyrosine Kinase Signaling Pathway and the p53 Tumor Suppressor Protein Exist In A Novel Regulatory Loop In B-Cell Chronic Lymphocytic Leukemia Cells

Linker of Activation of T Cells – 2 (LAT2), a Lipid Raft-Associated Adaptor Protein, Is a Novel Target for Therapy in Acute Leukemia

A Lymphoma-Associated Mutation in BAFF-R Drives Constitutive PI3K Signaling and Increased Expression of Pro-Survival Genes

Tissue Factor Is Internalized by Platelets Through Activation of RhoA and PI 3 -Kinase Promoting Reversible Cytoskeletal Assembly,

The Role of Akt3 in Mediating Outside-in Signaling of the Platelet Integrin αIIbβ3

Genomic and Pathway Connectivity Analyses Identify Novel Strategies to Overcome mTOR Inhibitor Resistance In DLBCL

Reconstitution of PTEN activity by CK2 inhibitors and interference with the PI3-K/Akt cascade counteract the antiapoptotic effect of human stromal cells in chronic lymphocytic leukemia

Factor XII stimulates ERK1/2 and Akt through uPAR, integrins, and the EGFR to initiate angiogenesis

PfPI3K, a phosphatidylinositol-3 kinase from Plasmodium falciparum , is exported to the host erythrocyte and is involved in hemoglobin trafficking

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American Society of Hematology

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ASH Publications

American Society of Hematology

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