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Journal Articles

Gfi1 Upregulates c-Myc Expression and Promotes c-Myc-Driven Cell Proliferation

Yangyang Zhang, MD, Fan Dong, MD PhD

Blood (2019) 134 (Supplement_1): 3769.

https://doi.org/10.1182/blood-2019-124833

Published: 2019

Journal Articles

Drug Resistance to the HDM-2 Inhibitors MI-63 and Nutlin Is Mediated by Point Mutations of p53, but Can Be Overcome with the p53 Targeting Agent RITA

Richard Julian Jones, PhD, Robert Z. Orlowski, MD, PhD

Blood (2011) 118 (21): 2726.

https://doi.org/10.1182/blood.V118.21.2726.2726

Published: 2011

Journal Articles

Preclinical Assessment of a Novel CDC7 Inhibitor: Genomewide RNAi Screening Identifies Unique Synergetic and Resistance Genes,

Nancy Liu-Sullivan, Bhavneet Bhinder, David Shum, Christina Ramirez, Constantin Radu, Hakim Djaballah, PhD, Mark G. Frattini, MD, PhD

Blood (2011) 118 (21): 3570.

https://doi.org/10.1182/blood.V118.21.3570.3570

Published: 2011

Journal Articles

Global Proteomic Profiling of Endemic Versus Sporadic Epstein-Barr Virus (EBV) Positive Burkitt Lymphoma (BL).

Nader El-Mallawany, MD, Janet Ayello, MS, MT, Nancy Day, Ph.D., Carmella van de Ven, MS, Kevin P Conlon, Damian Fermin, Venkatesha Basrur, Kojo S.J. Elenitoba-Johnson, Megan S Lim, MD, PhD, Mitchell S. Cairo, MD

Blood (2009) 114 (22): 4779.

https://doi.org/10.1182/blood.V114.22.4779.4779

Published: 2009

Journal Articles

TGF-β induces degradation of TAL1/SCL by the ubiquitin-proteasome pathway through AKT-mediated phosphorylation

Jean-Michel Terme, Ludovic Lhermitte, Vahid Asnafi, Pierre Jalinot

Blood (2009) 113 (26): 6695–6698.

https://doi.org/10.1182/blood-2008-07-166835

Published: 2009

Includes: Supplemental data

Journal Articles

Inhibition of the Human Double Minute (HDM)-2 E3 Ubiquitin Ligase Activates Different Programmed Cell Death (PCD) Pathways in Models of Non-Hodgkin Lymphoma (NHL) with Wild Type (wt) and Mutant (mut) p53

Richard Julian Jones, PhD, Janine Arts, PhD, Robert Z Orlowski, MD, PhD

Blood (2008) 112 (11): 3618.

https://doi.org/10.1182/blood.V112.11.3618.3618

Published: 2008

Journal Articles

Inhibition of Ubiquitin-Proteasome Pathway Causes Growth Suppression and Induces Apoptosis in Diffuse Large B Cell Lymphoma.

Shahab Uddin, PhD, Azhar Hussain, MBBS, Asma Khan, HS, Prashant Bavi, MD, Khawla Al-Kuraya, MD

Blood (2007) 110 (11): 1571.

https://doi.org/10.1182/blood.V110.11.1571.1571

Published: 2007

Journal Articles

Gene Expression Profile in the CML Cell Line K562 Treated with SKI-606, a Dual Inhibitor of Src/Abl Kinase.

Matteo Renzulli, Tiziana Grafone, Cristian Taccioli, Carolina Terragna, Frank Boschelli, Manuela Mancini, Pasquale Creo, Emanuela Ottaviani, Sabrina Colarossi, Marilina Amabile, Simona Soverini, Angela Poerio, Ilaria Iacobucci, Michele Baccarani, Giovanni Martinelli

Blood (2005) 106 (11): 4870.

https://doi.org/10.1182/blood.V106.11.4870.4870

Published: 2005

Journal Articles

Potent Activity of a Novel, Irreversible Inhibitor of the Ubiquitin-Proteasome Pathway Against Pre-Clinical Models of Multiple Myeloma.

Deborah J. Kuhn, PhD, Peter M. Voorhees, MD, John S. Strader, PA, Kevin D. Shenk, PhD, Congcong M. Sun, PhD, Susan D. Demo, PhD, Mark K. Bennett, PhD, Robert Z. Orlowski, MD, PhD

Blood (2005) 106 (11): 1576.

https://doi.org/10.1182/blood.V106.11.1576.1576

Published: 2005

Journal Articles

A Proteasome Specific Binding Assay for Quantitation of Constitutive and Immunoproteasome Active Sites.

Mark K. Bennett, PhD, Monette A. Aujay, BS, Tonia J. Buchholz, MS, Susan D. Demo, PhD, Guy J. Laidig, PhD, Congcong M. Sun, MS, Marcy K. Vallone, BS, Tina Woo, BS, Mark S. Smyth, PhD

Blood (2005) 106 (11): 2472.

https://doi.org/10.1182/blood.V106.11.2472.2472

Published: 2005

Journal Articles

Targeting IKK Inhibits Multiple Myeloma (MM) Cell Growth in the Bone Marrow Microenvironment.

Teru Hideshima, MD, PhD, Pierfrancesco Tassone, MD, Dharminder Chauhan, PhD, Kenji Ishitsuka, MD, PhD, Constantine Mitsiades, MD, PhD, Noopur Raje, MD, Shaji Kumar, MD, Makoto Hamasaki, MD, PhD, Hiromasa Hideshima, Nikhil C. Munshi, MD, Paul G. Richardson, MD, David Schenkein, MD, Kenneth C. Anderson, MD

Blood (2004) 104 (11): 2351.

https://doi.org/10.1182/blood.V104.11.2351.2351

Published: 2004

NARROW

Gfi1 Upregulates c-Myc Expression and Promotes c-Myc-Driven Cell Proliferation

Drug Resistance to the HDM-2 Inhibitors MI-63 and Nutlin Is Mediated by Point Mutations of p53, but Can Be Overcome with the p53 Targeting Agent RITA

Preclinical Assessment of a Novel CDC7 Inhibitor: Genomewide RNAi Screening Identifies Unique Synergetic and Resistance Genes,

Global Proteomic Profiling of Endemic Versus Sporadic Epstein-Barr Virus (EBV) Positive Burkitt Lymphoma (BL).

TGF-β induces degradation of TAL1/SCL by the ubiquitin-proteasome pathway through AKT-mediated phosphorylation

Inhibition of the Human Double Minute (HDM)-2 E3 Ubiquitin Ligase Activates Different Programmed Cell Death (PCD) Pathways in Models of Non-Hodgkin Lymphoma (NHL) with Wild Type (wt) and Mutant (mut) p53

Inhibition of Ubiquitin-Proteasome Pathway Causes Growth Suppression and Induces Apoptosis in Diffuse Large B Cell Lymphoma.

Gene Expression Profile in the CML Cell Line K562 Treated with SKI-606, a Dual Inhibitor of Src/Abl Kinase.

Potent Activity of a Novel, Irreversible Inhibitor of the Ubiquitin-Proteasome Pathway Against Pre-Clinical Models of Multiple Myeloma.

A Proteasome Specific Binding Assay for Quantitation of Constitutive and Immunoproteasome Active Sites.

Targeting IKK Inhibits Multiple Myeloma (MM) Cell Growth in the Bone Marrow Microenvironment.

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American Society of Hematology

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American Society of Hematology

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