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Journal Articles

Biology of PD-1 Checkpoint Blockade

Arlene H. Sharpe, MD PhD

Blood (2017) 130 (Supplement 1): SCI-35.

https://doi.org/10.1182/blood.V130.Suppl_1.SCI-35.SCI-35

Published: 2017

Journal Articles

New Approaches to Human Immunology

Mark Davis, PhD

Blood (2017) 130 (Supplement 1): SCI-47.

https://doi.org/10.1182/blood.V130.Suppl_1.SCI-47.SCI-47

Published: 2017

Journal Articles

Tolerization of CD4+ Recent Thymic Emigrants Is Required to Prevent RBC-Specific Autoimmunity

Andrea S.L. Wong, PhD, Amanda L Richards, Krystalyn E Hudson, PhD

Blood (2017) 130 (Supplement 1): 2283.

https://doi.org/10.1182/blood.V130.Suppl_1.2283.2283

Published: 2017

Journal Articles

Peripheral but Not Central Tolerance Regulates RBC Autoreactive CD4 + T Cells in a Novel Mouse

Sut Ling Wong, PhD, Amanda L Richards, James C. Zimring, MD PhD, Krystalyn E. Hudson, PhD

Blood (2015) 126 (23): 3441.

https://doi.org/10.1182/blood.V126.23.3441.3441

Published: 2015

Journal Articles

Activation of the Sting Pathway Enhances Immunity and Improves Survival in a Murine Myeloid Leukemia Model

Emily K. Curran, MD, Xiufen Chen, PhD, Leticia Corrales, PhD, Justin Kline, MD

Blood (2014) 124 (21): 3759.

https://doi.org/10.1182/blood.V124.21.3759.3759

Published: 2014

Journal Articles

Central T Cell Tolerance and Peripheral B Cell Tolerance for An RBC Autoantigen Are Incomplete in Healthy Mice; Implications for AIHA Pathogenesis

Krystalyn E Hudson, Ph.D., Jeanne Hendrickson, MD, Chantel M Cadwell, Neal N Iwakoshi, Ph.D., James C. Zimring, MD, PhD

Blood (2011) 118 (21): 693.

https://doi.org/10.1182/blood.V118.21.693.693

Published: 2011

Journal Articles

Age-Related Decrease of Human CD8 + T-Cell Mir-92a Level Correlated with Reduction of naïve T Lymphocyte

Michiyo Ohyashiki, MD, Junko H Ohyashiki, MD, PhD, Ayako Hirota, Chiaki Kobayashi, Kazuma Ohyashiki, MD, PhD

Blood (2011) 118 (21): 2186.

https://doi.org/10.1182/blood.V118.21.2186.2186

Published: 2011

Journal Articles

Tr17: A Unique Subset of T Regulatory Cells with Distinct Molecular and Functional Properties

Lequn Li, MD, PhD, Vassiliki A Boussiotis, MD, PhD

Blood (2011) 118 (21): 1116.

https://doi.org/10.1182/blood.V118.21.1116.1116

Published: 2011

Journal Articles

LAG-3, TGF-β, and cell-intrinsic PD-1 inhibitory pathways contribute to CD8 but not CD4 T-cell tolerance induced by allogeneic BMT with anti-CD40L

Carrie L. Lucas, Creg J. Workman, Semir Beyaz, Samuel LoCascio, Guiling Zhao, Dario A. A. Vignali, Megan Sykes

Blood (2011) 117 (20): 5532–5540.

https://doi.org/10.1182/blood-2010-11-318675

Published: 2011

Journal Articles

Down-Regulation of Signal Transducer and Activator of Transcription 3 Enhances Acute Myeloid Leukemia-Derived Dendritic Cell Function

Michael T Brady, PhD, Austin Miller, PhD, Sheila Sait, PhD, Laurie A Ford, BS, CCRC, Minderman Hans, PhD, Eunice S. Wang, MD, Kelvin P Lee, MD, Heinz Baumann, Meir Wetzler, MD

Blood (2010) 116 (21): 3140.

https://doi.org/10.1182/blood.V116.21.3140.3140

Published: 2010

Journal Articles

B7-H1/CD80 interaction is required for the induction and maintenance of peripheral T-cell tolerance

Jang-June Park, Ryusuke Omiya, Yumiko Matsumura, Yukimi Sakoda, Atsuo Kuramasu, Mathew M. Augustine, Sheng Yao, Fumihiko Tsushima, Hidehiko Narazaki, Sudarshan Anand, Yingjia Liu, Scott E. Strome, Lieping Chen, Koji Tamada

Blood (2010) 116 (8): 1291–1298.

https://doi.org/10.1182/blood-2010-01-265975

Published: 2010

Includes: Supplemental data

Journal Articles

Irradiation and IL-15 promote loss of CD8 T-cell tolerance in response to lymphopenia

Thilo Oelert, Maria Papatriantafyllou, Georg Pougialis, Günter J. Hämmerling, Bernd Arnold, Thomas Schüler

Blood (2010) 115 (11): 2196–2202.

https://doi.org/10.1182/blood-2009-06-227298

Published: 2010

Includes: Supplemental data

Journal Articles

Over-Expression of IDO in NHL Results in Conversion of CD4+CD25- T Cells Into CD4+CD25+ T Cells.

Xin Wang, MD, PhD, Xiaoqian Liu, MM, Jinyao Ning, MM, Lili Feng, Li Shi, PhD

Blood (2009) 114 (22): 1931.

https://doi.org/10.1182/blood.V114.22.1931.1931

Published: 2009

Journal Articles

Induction of type I IFN is required for overcoming tumor-specific T-cell tolerance after stem cell transplantation

Ian Horkheimer, Michael Quigley, Jiangao Zhu, Xiaopei Huang, Nelson J. Chao, Yiping Yang

Blood (2009) 113 (21): 5330–5339.

https://doi.org/10.1182/blood-2008-05-155150

Published: 2009

Journal Articles

Critical Role of Neutrophils in Determining Antigen-Specific CD4+ T-Cell Tolerance In Vivo.

Fengdong Cheng, MD, Pedro Horna, M.D., Hongwei Wang, M.D., Ildefonso Suarez, PhD, Xianhong Chen, M.S, Shen Wei, PhD, Eduardo M. Sotomayor, M.D.

Blood (2007) 110 (11): 3294.

https://doi.org/10.1182/blood.V110.11.3294.3294

Published: 2007

Journal Articles

A Novel p27 kip1 -Smad3 Regulated Pathway Is Involved in Induction of T Cell Tolerance.

Lequn Li, MD, PhD, Yoshiko Iwamoto, Alla Berezovskaya, Vassiliki A. Boussiotis, MD, PhD

Blood (2006) 108 (11): 867.

https://doi.org/10.1182/blood.V108.11.867.867

Published: 2006

Journal Articles

Treatment of Antigen-Presenting Cells with Histone Deacetylase Inhibitors Represents a Novel Strategy To Overcome CD4+ T-Cell Tolerance: Divergent Effects on the IL10 and IL-12 Promoter.

Hongwei Wang, MD, Fengdong Cheng, MD, P. Horna, MD, I.V. Suarez, PhD, Jian Wu, PhD, A.P. Atadja, PhD, E. Seto, PhD, K. Wright, PhD, K. Bhalla, MD, E.M. Sotomayor, MD

Blood (2005) 106 (11): 2392.

https://doi.org/10.1182/blood.V106.11.2392.2392

Published: 2005

Journal Articles

Cucurbitacins, a Family of Natural Compounds That Effectively Disrupt Stat3 Signaling in Antigen-Presenting Cells (APCs) Are Promising Agents To Overcome Tumor-Induced CD4+ T-Cell Tolerance.

Fengdong Cheng, MD, Hongwei Wang, MD, Alfonso Suarez, Pedro Horna, MD, Said Sebti, PhD, Eduardo M. Sotomayor, MD

Blood (2005) 106 (11): 1485.

https://doi.org/10.1182/blood.V106.11.1485.1485

Published: 2005

Journal Articles

CD8α – 11b + dendritic cells but not CD8α + dendritic cells mediate cross-tolerance toward intestinal antigens

Yeonseok Chung, Jae-Hoon Chang, Mi-Na Kweon, Paul D. Rennert, Chang-Yuil Kang

Blood (2005) 106 (1): 201–206.

https://doi.org/10.1182/blood-2004-11-4240

Published: 2005

Includes: Supplemental data

Journal Articles

Imatinib mesylate (STI-571) enhances antigen-presenting cell function and overcomes tumor-induced CD4 + T-cell tolerance

Hongwei Wang, Fengdong Cheng, Alex Cuenca, Pedro Horna, Zheng Zheng, Kapil Bhalla, Eduardo M. Sotomayor

Blood (2005) 105 (3): 1135–1143.

https://doi.org/10.1182/blood-2004-01-0027

Published: 2005

NARROW

Biology of PD-1 Checkpoint Blockade

New Approaches to Human Immunology

Tolerization of CD4+ Recent Thymic Emigrants Is Required to Prevent RBC-Specific Autoimmunity

Peripheral but Not Central Tolerance Regulates RBC Autoreactive CD4 + T Cells in a Novel Mouse

Activation of the Sting Pathway Enhances Immunity and Improves Survival in a Murine Myeloid Leukemia Model

Central T Cell Tolerance and Peripheral B Cell Tolerance for An RBC Autoantigen Are Incomplete in Healthy Mice; Implications for AIHA Pathogenesis

Age-Related Decrease of Human CD8 + T-Cell Mir-92a Level Correlated with Reduction of naïve T Lymphocyte

Tr17: A Unique Subset of T Regulatory Cells with Distinct Molecular and Functional Properties

LAG-3, TGF-β, and cell-intrinsic PD-1 inhibitory pathways contribute to CD8 but not CD4 T-cell tolerance induced by allogeneic BMT with anti-CD40L

Down-Regulation of Signal Transducer and Activator of Transcription 3 Enhances Acute Myeloid Leukemia-Derived Dendritic Cell Function

B7-H1/CD80 interaction is required for the induction and maintenance of peripheral T-cell tolerance

Irradiation and IL-15 promote loss of CD8 T-cell tolerance in response to lymphopenia

Over-Expression of IDO in NHL Results in Conversion of CD4+CD25- T Cells Into CD4+CD25+ T Cells.

Induction of type I IFN is required for overcoming tumor-specific T-cell tolerance after stem cell transplantation

Critical Role of Neutrophils in Determining Antigen-Specific CD4+ T-Cell Tolerance In Vivo.

A Novel p27 kip1 -Smad3 Regulated Pathway Is Involved in Induction of T Cell Tolerance.

Treatment of Antigen-Presenting Cells with Histone Deacetylase Inhibitors Represents a Novel Strategy To Overcome CD4+ T-Cell Tolerance: Divergent Effects on the IL10 and IL-12 Promoter.

Cucurbitacins, a Family of Natural Compounds That Effectively Disrupt Stat3 Signaling in Antigen-Presenting Cells (APCs) Are Promising Agents To Overcome Tumor-Induced CD4+ T-Cell Tolerance.

CD8α – 11b + dendritic cells but not CD8α + dendritic cells mediate cross-tolerance toward intestinal antigens

Imatinib mesylate (STI-571) enhances antigen-presenting cell function and overcomes tumor-induced CD4 + T-cell tolerance

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American Society of Hematology

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American Society of Hematology

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