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Journal Articles

Ibrutinib-Based Therapy Improves Anti-Tumor T Cell Killing Function Allowing Effective Pairing with Anti-PD-L1 Immunotherapy Compared to Traditional FCR Chemoimmunotherapy; Implications for Therapy and Correlative Immune Functional Data from the Phase III E1912 Trial

Despoina Papazoglou, BSc, Connie E. Lesnick, Victoria Wang, Neil E. Kay, MD, Tait D. Shanafelt, MD, Alan G. Ramsay, BSc,MSc,PhD

Blood (2018) 132 (Supplement 1): 236.

https://doi.org/10.1182/blood-2018-99-118333

Published: 2018

Journal Articles

Functional Signatures Revealed By Deep Phenotyping of CMV-Specific CD8+ T Cells Predict Risk of Early CMV Reactivation after Allogeneic Hematopoietic Cell Transplantation

Jose F Camargo, MD, Eric Wieder, PhD, Erik Kimble, MD, Cara Benjamin, PhD, Despina Kolonias, Gabriela Bravo, MD, Krishna Komanduri, MD

Blood (2017) 130 (Supplement 1): 746.

https://doi.org/10.1182/blood.V130.Suppl_1.746.746

Published: 2017

Journal Articles

Notch Signaling Mediated By Dll1/4 Notch Ligands Controls the Pathogenesis of Both Multi-Organ System Non-Sclerodermatous and Sclerodermatous Chronic Graft-Versus-Host Disease

Vedran Radojcic, MD, Ryan P Flynn, PhD, Jooho Chung, BS, Jing Du, Eric Perkey, BS, Katelyn Paz, Michael Zaiken, Ann Friedman, Minhong Yan, PhD, Christian W. Siebel, PhD, Bruce R. Blazar, MD, Ivan Maillard, MD PhD

Blood (2016) 128 (22): 805.

https://doi.org/10.1182/blood.V128.22.805.805

Published: 2016

Journal Articles

CC-122 Repairs T Cell Activation in Chronic Lymphocytic Leukemia That Results in a Concomitant Increase in PD-1:PD-L1 and CTLA-4 Immune Checkpoint Expression at the Immunological Synapse

Benedetta Apollonio, PhD, Mariam Fanous, BSc, MSc, Mohamed-Reda Benmebarek, BSc, MRes, Stephen Devereux, FRCP, FRCPath, PhD, Patrick Hagner, PhD, Michael Pourdehnad, MD, Anita K. Gandhi, PhD, Piers E. Patten, BSc, MRCP, MRCPath, PhD, Alan G. Ramsay, PhD

Blood (2015) 126 (23): 1738.

https://doi.org/10.1182/blood.V126.23.1738.1738

Published: 2015

Journal Articles

Prenatal Allospecific Tolerance Is Characterized By Early T reg Expansion and a Surprisingly Slow Pace for T eff Clonal Deletion

Beverly SI Strong, PhD, Amanda E Lee, MD, Tess J Newkold, Lucas E Turner, Aimen F Shaaban, MD

Blood (2015) 126 (23): 3070.

https://doi.org/10.1182/blood.V126.23.3070.3070

Published: 2015

Journal Articles

Abrogation of Myeloid Derived Suppressor Cell-Like Inhibitory Activity of K562 Restores Antigen Presenting Cell Functions

Kazushi Tanimoto, MD, PhD, Pawel Muranski, MD, Nancy F. Hensel, BS, Keyvan Keyvanfar, BS, Hiroshi Fujiwara, MD, PhD, A. John Barrett, MD, J. Joseph Melenhorst, PhD

Blood (2012) 120 (21): 4118.

https://doi.org/10.1182/blood.V120.21.4118.4118

Published: 2012

Journal Articles

Improved Strategy for Rapid Generation of Quadrivirus-Specific CD8+ and CD4+ Cytotoxic T Lymphocytes (CTLs) for Adoptive Transfer After Stem Cell Transplantation (SCT)

Alexandros Spyridonidis, MD, Pawel Muranski, MD, Sid Kerkar, MD, Kazushi Tanimoto, MD, Nancy F. Hensel, BS, J. Joseph Melenhorst, PhD, A. John Barrett, MD

Blood (2012) 120 (21): 4121.

https://doi.org/10.1182/blood.V120.21.4121.4121

Published: 2012

Journal Articles

Hierarchical Clustering of B-Cell Receptor Structures in Splenic Marginal Zone Lymphoma

Paolo Marcatili, Silvia Zibellini, Sara Rattotti, Anna Chailyan, Marzia Varettoni, Lucia Morello, Emanuela Boveri, Marco Lucioni, Maurizio Bonfichi, Manuel Gotti, Valeria Fiaccadori, Marco Paulli, Anna Tramontano, Luca Arcaini

Blood (2012) 120 (21): 1585.

https://doi.org/10.1182/blood.V120.21.1585.1585

Published: 2012

Journal Articles

Clonal Selection in the Ontogeny and Evolution of Splenic Marginal Zone Lymphoma Confirming the Existence of Distinct Molecular Subtypes

Blood (2012) 120 (21): 1556.

https://doi.org/10.1182/blood.V120.21.1556.1556

Published: 2012

Journal Articles

Recombinant antibodies encoded by IGHV1-69 react with pUL32, a phosphoprotein of cytomegalovirus and B-cell superantigen

Christoph Steininger, George F. Widhopf, II, Emanuela M. Ghia, Christopher S. Morello, Katrina Vanura, Rebecca Sanders, Deborah Spector, Don Guiney, Ulrich Jäger, Thomas J. Kipps

Blood (2012) 119 (10): 2293–2301.

https://doi.org/10.1182/blood-2011-08-374058

Published: 2012

Journal Articles

Clues to the Pathogenesis of Waldenström Macroglobulinemia and Other Monoclonal IgM Disorders Provided by the Analysis of Immunoglobulin Heavy Chain Gene Rearrangement and Clustering of B-Cell Receptors,

Silvia Zibellini, Marzia Varettoni, Daniela Capello, Luca Arcaini, Davide Rossi, Ester Orlandi, Emanuela Boveri, Sara Rattotti, Cristiana Pascutto, Silvia Rizzi, Gianluca Gaidano, Mario Cazzola

Blood (2011) 118 (21): 3680.

https://doi.org/10.1182/blood.V118.21.3680.3680

Published: 2011

Journal Articles

Primary Intraocular Lymphomas Display A Remarkably Biased Immunoglobulin Heavy Chain Gene Repertoire and Precisely Targeted Somatic Hypermutation Suggesting Antigenic Selection of the Neoplastic Cells

Nabila Belhouachi, Evangelia Stalika, Bahram Bodaghi, Myriam Boudjoghra, Nathalie Cassoux, Christine Fardeau, Sylvie Baudet, Phuc Le Hoang, Helene Merle-Beral, Kostas Stamatopoulos, MD, Frederic Davi

Blood (2011) 118 (21): 1574.

https://doi.org/10.1182/blood.V118.21.1574.1574

Published: 2011

Journal Articles

Somatic Hypermutation In Stereotyped Subset 4 BCRs/mAbs of CLL Patients, Expressing IGHV4-34 gene, Edit Anti-DNA Reactivity

Rosa Catera, Ph.D., Amanda R Magli, BSE, Jonathan E Kolitz, MD, Steven L. Allen, MD, Kanti R Rai, MD, Charles C Chu, PhD, Kostas Stamatopoulos, MD, Nicholas Chiorazzi, MD

Blood (2010) 116 (21): 2444.

https://doi.org/10.1182/blood.V116.21.2444.2444

Published: 2010

Journal Articles

Analysis of Immunoglobulin Heavy Chain Variable Genes In Burkitt Lymphoma Uncovers An Antigen Role In the Pathogenesis of the Disease

Maria Joao Baptista, MSc, Marta Crespo, PhD, Eva Calpe, Carles Codony, PhD, Eva Fernandez, Lluis Colomo, MD, PhD, Teresa Marta Cardesa-Salzmann, MD, Pau Abrisqueta, MD, Francesc Bosch, MD, PhD

Blood (2010) 116 (21): 4135.

https://doi.org/10.1182/blood.V116.21.4135.4135

Published: 2010

Journal Articles

Functional Screening Studies Identify Combinational Activity of PD-L1 and CD200 In Mediating Dysfunctional T Cell Immunological Synapse Formation In Chronic Lymphocytic Leukemia

Alan G. Ramsay, PhD, Andrew James Clear, Alexander Davenport, Rewas Fatah, John G. Gribben, MD, DSc

Blood (2010) 116 (21): 696.

https://doi.org/10.1182/blood.V116.21.696.696

Published: 2010

Journal Articles

Transient but Reversible Activation Defect of T-Cell Responses Against Cytomegalovirus and Adenovirus through Immunosuppresion with Calcineurin Inhibitors.

Cornelia Neinhaus, Kathrin Opherk, Simone Kayser, Joseph Leibold, Judith Feucht, Peter Lang, Rupert Handgretinger, MD, PhD, Tobias F. Feuchtinger, MD

Blood (2010) 116 (21): 4542.

https://doi.org/10.1182/blood.V116.21.4542.4542

Published: 2010

Journal Articles

Integrin and CD3/TCR activation are regulated by the scaffold protein AKAP450

Javier Robles-Valero, Noa B. Martín-Cófreces, Amalia Lamana, Stephen Macdonald, Yuri Volkov, Francisco Sánchez-Madrid

Blood (2010) 115 (21): 4174–4184.

https://doi.org/10.1182/blood-2009-12-256222

Published: 2010

Includes: Multimedia, Supplemental data

Journal Articles

Chronic Lymphocytic Leukemia Subset Expressing Mutated IGHV3-23 Has Peculiar Clinical and Biological Features.

Blood (2009) 114 (22): 1256.

https://doi.org/10.1182/blood.V114.22.1256.1256

Published: 2009

Journal Articles

Evidence for Antigen-Driven Development of Molecularly Classified Burkitt Lymphomas.

Heiko Trautmann, PhD, Anastasia Hadzidimitriou, PhD, Nikos Darzentas, PhD, Wolfram Klapper, MD, Reiner Siebert, MD, Hilmar Berger, MD, Monika Szczepanowski, MD, Michael Kneba, MD, PhD, Claudia Philipp, PhD, Ralf Küppers, PhD, Kostas Stamatopoulos, MD, Christiane Pott, MD

Blood (2009) 114 (22): 317.

https://doi.org/10.1182/blood.V114.22.317.317

Published: 2009

Journal Articles

Lack of “Bystander” Activation and Evidence for Competition for Resources among Gvh-Reactive CD4 T Cells

Giovanna Andreola, MD, Meredith Chittenden, Megan Sykes, MD

Blood (2008) 112 (11): 3507.

https://doi.org/10.1182/blood.V112.11.3507.3507

Published: 2008

NARROW

Ibrutinib-Based Therapy Improves Anti-Tumor T Cell Killing Function Allowing Effective Pairing with Anti-PD-L1 Immunotherapy Compared to Traditional FCR Chemoimmunotherapy; Implications for Therapy and Correlative Immune Functional Data from the Phase III E1912 Trial

Functional Signatures Revealed By Deep Phenotyping of CMV-Specific CD8+ T Cells Predict Risk of Early CMV Reactivation after Allogeneic Hematopoietic Cell Transplantation

Notch Signaling Mediated By Dll1/4 Notch Ligands Controls the Pathogenesis of Both Multi-Organ System Non-Sclerodermatous and Sclerodermatous Chronic Graft-Versus-Host Disease

CC-122 Repairs T Cell Activation in Chronic Lymphocytic Leukemia That Results in a Concomitant Increase in PD-1:PD-L1 and CTLA-4 Immune Checkpoint Expression at the Immunological Synapse

Prenatal Allospecific Tolerance Is Characterized By Early T reg Expansion and a Surprisingly Slow Pace for T eff Clonal Deletion

Abrogation of Myeloid Derived Suppressor Cell-Like Inhibitory Activity of K562 Restores Antigen Presenting Cell Functions

Improved Strategy for Rapid Generation of Quadrivirus-Specific CD8+ and CD4+ Cytotoxic T Lymphocytes (CTLs) for Adoptive Transfer After Stem Cell Transplantation (SCT)

Hierarchical Clustering of B-Cell Receptor Structures in Splenic Marginal Zone Lymphoma

Clonal Selection in the Ontogeny and Evolution of Splenic Marginal Zone Lymphoma Confirming the Existence of Distinct Molecular Subtypes

Recombinant antibodies encoded by IGHV1-69 react with pUL32, a phosphoprotein of cytomegalovirus and B-cell superantigen

Clues to the Pathogenesis of Waldenström Macroglobulinemia and Other Monoclonal IgM Disorders Provided by the Analysis of Immunoglobulin Heavy Chain Gene Rearrangement and Clustering of B-Cell Receptors,

Primary Intraocular Lymphomas Display A Remarkably Biased Immunoglobulin Heavy Chain Gene Repertoire and Precisely Targeted Somatic Hypermutation Suggesting Antigenic Selection of the Neoplastic Cells

Somatic Hypermutation In Stereotyped Subset 4 BCRs/mAbs of CLL Patients, Expressing IGHV4-34 gene, Edit Anti-DNA Reactivity

Analysis of Immunoglobulin Heavy Chain Variable Genes In Burkitt Lymphoma Uncovers An Antigen Role In the Pathogenesis of the Disease

Functional Screening Studies Identify Combinational Activity of PD-L1 and CD200 In Mediating Dysfunctional T Cell Immunological Synapse Formation In Chronic Lymphocytic Leukemia

Transient but Reversible Activation Defect of T-Cell Responses Against Cytomegalovirus and Adenovirus through Immunosuppresion with Calcineurin Inhibitors.

Integrin and CD3/TCR activation are regulated by the scaffold protein AKAP450

Chronic Lymphocytic Leukemia Subset Expressing Mutated IGHV3-23 Has Peculiar Clinical and Biological Features.

Evidence for Antigen-Driven Development of Molecularly Classified Burkitt Lymphomas.

Lack of “Bystander” Activation and Evidence for Competition for Resources among Gvh-Reactive CD4 T Cells

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American Society of Hematology

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American Society of Hematology

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