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Journal Articles

Increased Methylation of Deamidated Asparagines and Aspartates in Stored Red Blood Cells from Glucose 6-Phosphate Dehydrogenase-Deficient Blood Donors

Blood (2018) 132 (Supplement 1): 2543.

https://doi.org/10.1182/blood-2018-99-119262

Published: 2018

Journal Articles

S-Adenosyl Methionine Synthesis Impacts Maintenance of Acute Myeloid Leukemia Cells with Regulation of Transcriptional Elongation

Alice V Taylor, BSc PGCE, Rita Romano Adao, MPharm, Cecilia Castro, PhD, Ana Filipa Domingues, MSc, Jules L Griffin, PhD, Antonio Curti, Cristina Pina, MD DPhil

Blood (2018) 132 (Supplement 1): 2605.

https://doi.org/10.1182/blood-2018-99-115004

Published: 2018

Journal Articles

Targeting the Mitochondrial Metallochaperone Cox17 Reduces DNA Methylation and Promotes AML Differentiation through a Copper Dependent Mechanism

Blood (2018) 132 (Supplement 1): 1339.

https://doi.org/10.1182/blood-2018-99-111015

Published: 2018

Journal Articles

Contrasting Stage Dependent Requirements for the Histone Methyltransferase EZH2 during the Evolution of Acute Myeloid Leukemia

Faisal Basheer, MBBChir, MA, George Giotopoulos, PhD, Eshwar Meduri, PhD, Haiyang Yun, PhD, Milena Mazan, PhD, Olivia Sheppard, Daniel Sasca, MD, Malgorzata Gozdecka, PhD, George S. Vassiliou, MD PhD, Brian J.P Huntly

Blood (2017) 130 (Supplement 1): 1215.

https://doi.org/10.1182/blood.V130.Suppl_1.1215.1215

Published: 2017

Journal Articles

Functional and Molecular Consequences of the Dnmt3aR882H Mutation in Acute Myeloid Leukaemia

Malgorzata Gozdecka, PhD, Milena M. Mazan, PhD, Vivek Iyer, Anna Farne, Eshwar Meduri, Ruben Bautista, Nicolas Walker, Anne C Ferguson-Smith, PhD, George S. Vassiliou, MD PhD, Brian J.P Huntly, MD PhD

Blood (2015) 126 (23): 2424.

https://doi.org/10.1182/blood.V126.23.2424.2424

Published: 2015

Journal Articles

Betaine for Patients with Acute Lymphoblastic Leukemia Intolerant of Maintenance Chemotherapy Due Deficiency of S-Adenosyl Methionine

Bruce Bostrom, MD, Bhoopatiraju Sweta, S. Jill James, PhD

Blood (2015) 126 (23): 1296.

https://doi.org/10.1182/blood.V126.23.1296.1296

Published: 2015

Journal Articles

High Throughput Screening Identifies Potential Inhibitors of WHSC1/MMSET, a Histone Methyltransferase Oncoprotein in Multiple Myeloma and Acute Lymphocytic Leukemia

Christine M Will, MS, Michael Scholle, MS, Roodolph St. Pierre, BS, Gary Schiltz, PhD, James E. Bradner, MD, Milan Mrksich, PhD, Jonathan D. Licht, MD

Blood (2015) 126 (23): 3251.

https://doi.org/10.1182/blood.V126.23.3251.3251

Published: 2015

Journal Articles

Maintenance of Pluripotent Stem Cells is Influenced by Ser/Thr Metabolism

Lewis C. Cantley, PhD

Blood (2014) 124 (21): SCI-43.

https://doi.org/10.1182/blood.V124.21.SCI-43.SCI-43

Published: 2014

Journal Articles

Structure-Guided Design of DOT1L Methyltransferase Inhibitors By a Novel, Label Free Assay Platform

Joanna S. Yi, MD, Alex Federation, Jun Qi, PhD, Sirano Dhe-Paganon, PhD, Michael Hadler, MSc, Xiang Xu, PhD, Anthony Varca, Roodolph St. Pierre, Scott A. Armstrong, MD PhD, James E. Bradner

Blood (2014) 124 (21): 4811.

https://doi.org/10.1182/blood.V124.21.4811.4811

Published: 2014

Journal Articles

Targeting Folate Metabolism In Acute Myelogenous Leukemia

Yana Pikman, MD, Alexandre Puissant, PhD, Gabriela Alexe, PhD, Stacey M. Frumm, Linda Ross, PhD, Liying Chen, Ph.D., Nina Fenouille, PhD, Christopher F Bassil, Clary B. Clish, PhD, Andrew L Kung, MD, PhD, Michael T Hemann, PhD, Versha Banerji, MD, Kimberly Stegmaier, MD

Blood (2013) 122 (21): 3798.

https://doi.org/10.1182/blood.V122.21.3798.3798

Published: 2013

Journal Articles

Combined Epigenetic and Immunotherapy For Newly Diagnosed Mantle Cell Lymphoma: Correlative Studies Suggest The Importance Of Enhanced ADCC, Mechanisms of Resistance and Cyclin D1 Nuclear Localization Genotype

Kamal Sharma, DO, Violetta V. Leshchenko, PhD, Zainul Hasanali, BS, August Stuart, MS, Sara Shimko, BS, Stephen E Spurgeon, MD, Samir Parekh, MD, Elliot M Epner, MD Phd

Blood (2013) 122 (21): 3063.

https://doi.org/10.1182/blood.V122.21.3063.3063

Published: 2013

Journal Articles

Combination Therapy with Cladribine, Vorinostat, and Ofatumumab Achieves Complete Hematologic Remission in Refractory Classical Hairy Cell Leukemia

Vikas Ghai, MD, Kamal Sharma, DO, Kamal K.S. Abbi, Sara Shimko, BS, Elliot M Epner, MD, PhD

Blood (2011) 118 (21): 4622.

https://doi.org/10.1182/blood.V118.21.4622.4622

Published: 2011

Journal Articles

Mitochondrial Physiology in Health and Disease: Changes with Aging.

Douglas C. Wallace, PHD

Blood (2009) 114 (22): SCI-1.

https://doi.org/10.1182/blood.V114.22.SCI-1.SCI-1

Published: 2009

Journal Articles

Heightened Sulfur Amino Acid Oxidation in Plasma and Erythrocytes in β-Thalassemia Major.

Anurag K. Agrawal, MD, Jung H. Suh, PhD, Bruce N. Ames, PhD, Elliott P. Vichinsky, MD, Ashutosh Lal, MD

Blood (2009) 114 (22): 4065.

https://doi.org/10.1182/blood.V114.22.4065.4065

Published: 2009

Journal Articles

Double-Blind, Placebo-Controlled, Randomized Clinical Trial of the Effect of the Dietary Supplement S-Adenosyl-L-Methionine (AdoMet) on Plasma Homocysteine (Hcy) Levels in Healthy Human Subjects.

Michael A. Thompson, MD, PhD, Brent A. Bauer, MD, Laura L. Loehrer, Stephen S. Cha, MS, Jayawant N. Mandrekar, PhD, Amit Sood, MD, Dietland L. Wahner-Roedler, MD

Blood (2006) 108 (11): 1481.

https://doi.org/10.1182/blood.V108.11.1481.1481

Published: 2006

Journal Articles

Homocysteine Metabolism in Chuvash Polycythemia.

Heather M. Gilbert, MD, Adelina I. Sergueva, M.D., Victor R. Gordeuk, M.D., Josef T. Prchal, M.D.

Blood (2006) 108 (11): 4911.

https://doi.org/10.1182/blood.V108.11.4911.4911

Published: 2006

Journal Articles

Effects of Methionine Synthase (MS) A2756G and Methionine Synthase Reductase (MSR) A66G Polymorphisms on Methionine Metabolism in Brazilian Pregnant Women and Their Neonates.

Patricia R. Barbosa, Sally P. Stabler, MD, Mario H. Hirata, PhD, Rosario D.C. Hirata, PhD, Robert H. Allen, MD, Luiz F. Sampaio-Neto, PhD, Elvira M. Guerra-Shinohara, PhD

Blood (2004) 104 (11): 3686.

https://doi.org/10.1182/blood.V104.11.3686.3686

Published: 2004

Journal Articles

Interaction between Polymorphisms MTHFR C677T and MTRR A66G and Vitamin Levels in Pregnant Women.

Elvira M. Guerra-Shinohara, PhD, Patricia R. Barbosa, Luiz F. Sampaio-Neto, PhD, Rosario D. Hirata, PhD, Mario H. Hirata, PhD, Robert H. Allen, MD, Sally P. Stabler, MD

Blood (2004) 104 (11): 3687.

https://doi.org/10.1182/blood.V104.11.3687.3687

Published: 2004

Journal Articles

Sulfur- and Selenium-Containing Compounds Derived from Natural and Synthetic Sources in Angiogenesis Modulation.

Shaker A. Mousa, PhD, MBA, FACC, FACB, Seema Mohamed, MS, Laura O’Connor, BS, Eric Block, PhD

Blood (2004) 104 (11): 3924.

https://doi.org/10.1182/blood.V104.11.3924.3924

Published: 2004

Journal Articles

Cobalamin deficiency with and without neurologic abnormalities: differences in homocysteine and methionine metabolism: Presented in preliminary form at the 44th Annual Meeting of the American Society of Hematology, Philadelphia, PA, December 7, 2002.

Ralph Carmel, Stepan Melnyk, S. Jill James

Blood (2003) 101 (8): 3302–3308.

https://doi.org/10.1182/blood-2002-09-2746

Published: 2003

NARROW

Increased Methylation of Deamidated Asparagines and Aspartates in Stored Red Blood Cells from Glucose 6-Phosphate Dehydrogenase-Deficient Blood Donors

S-Adenosyl Methionine Synthesis Impacts Maintenance of Acute Myeloid Leukemia Cells with Regulation of Transcriptional Elongation

Targeting the Mitochondrial Metallochaperone Cox17 Reduces DNA Methylation and Promotes AML Differentiation through a Copper Dependent Mechanism

Contrasting Stage Dependent Requirements for the Histone Methyltransferase EZH2 during the Evolution of Acute Myeloid Leukemia

Functional and Molecular Consequences of the Dnmt3aR882H Mutation in Acute Myeloid Leukaemia

Betaine for Patients with Acute Lymphoblastic Leukemia Intolerant of Maintenance Chemotherapy Due Deficiency of S-Adenosyl Methionine

High Throughput Screening Identifies Potential Inhibitors of WHSC1/MMSET, a Histone Methyltransferase Oncoprotein in Multiple Myeloma and Acute Lymphocytic Leukemia

Maintenance of Pluripotent Stem Cells is Influenced by Ser/Thr Metabolism

Structure-Guided Design of DOT1L Methyltransferase Inhibitors By a Novel, Label Free Assay Platform

Targeting Folate Metabolism In Acute Myelogenous Leukemia

Combined Epigenetic and Immunotherapy For Newly Diagnosed Mantle Cell Lymphoma: Correlative Studies Suggest The Importance Of Enhanced ADCC, Mechanisms of Resistance and Cyclin D1 Nuclear Localization Genotype

Combination Therapy with Cladribine, Vorinostat, and Ofatumumab Achieves Complete Hematologic Remission in Refractory Classical Hairy Cell Leukemia

Mitochondrial Physiology in Health and Disease: Changes with Aging.

Heightened Sulfur Amino Acid Oxidation in Plasma and Erythrocytes in β-Thalassemia Major.

Double-Blind, Placebo-Controlled, Randomized Clinical Trial of the Effect of the Dietary Supplement S-Adenosyl-L-Methionine (AdoMet) on Plasma Homocysteine (Hcy) Levels in Healthy Human Subjects.

Homocysteine Metabolism in Chuvash Polycythemia.

Effects of Methionine Synthase (MS) A2756G and Methionine Synthase Reductase (MSR) A66G Polymorphisms on Methionine Metabolism in Brazilian Pregnant Women and Their Neonates.

Interaction between Polymorphisms MTHFR C677T and MTRR A66G and Vitamin Levels in Pregnant Women.

Sulfur- and Selenium-Containing Compounds Derived from Natural and Synthetic Sources in Angiogenesis Modulation.

Cobalamin deficiency with and without neurologic abnormalities: differences in homocysteine and methionine metabolism: Presented in preliminary form at the 44th Annual Meeting of the American Society of Hematology, Philadelphia, PA, December 7, 2002.

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American Society of Hematology

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American Society of Hematology

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