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Journal Articles

A Gain of Function Mutation in the NSD2 Histone Methyltransferase Drives Glucocorticoid Resistance Via Blocking Receptor Auto-Induction and BIM/Bmf Expression in ALL

Blood (2019) 134 (Supplement_1): 3758.

https://doi.org/10.1182/blood-2019-126910

Published: 2019

Journal Articles

Bach1 Inhibitors Reduce Stasis in Townes Sickle Cell Mouse Model

John D Belcher, PhD, Margaret Biddle, PhD, Domi Stickens, PhD, Lyndsay Olson, Eric Bell, Chunsheng Chen, Fuad Abdulla, Julia Nguyen, Zachary Monroe Kiser, BS, PhD, Jacob Lloyd, MD, Gregory M Vercellotti, MD

Blood (2019) 134 (Supplement_1): 983.

https://doi.org/10.1182/blood-2019-127300

Published: 2019

Journal Articles

Dependency of Spliceosomal Mutant MDS on Innate Immune Signaling

Stanley C Lee, PhD, Khrystyna North, Chi-Chao Chen, Eunhee Kim, PhD, Sydney X. Lu, MD PhD, Michelle Ki, BSc, Ralph Garippa, PhD, Scott W Lowe, PhD, Robert K. Bradley, PhD, Omar I Abdel-Wahab, MD

Blood (2018) 132 (Supplement 1): 937.

https://doi.org/10.1182/blood-2018-99-111552

Published: 2018

Journal Articles

Ets1 Enhances Context-Dependent Notch1 Activity in T-Cell Leukemia

Anna McCarter, BS, Ran Yan, Amparo Serna Alarcon, Catherine Chang, Erin Kim, Cher Sha, Yiran Liu, Qing Wang, PhD, Luke F. Peterson, PhD, Rork Kuick, Russell Ryan, MD, Moshe Talpaz, MD, Linda Samuelson, PhD, Michael Ostrowski, PhD, Mark Y Chiang, MD PhD

Blood (2018) 132 (Supplement 1): 2595.

https://doi.org/10.1182/blood-2018-99-111376

Published: 2018

Journal Articles

Hydroxyurea Exhibits Antioxidant Activity Via the Nrf2 Pathway- Antioxidant/Electrophile Response Element Regulated By p62/ SQSTM1

Sanzio Santana, MSc, Thassila Nogueira Pitanga, PhD, Jeanne Machado de Santana, Graduation student, Dalila Lucíola Zanette, PhD, Corynne Stephanie A. Adanho, MSc, Nívea Farias Luz, PhD, Valéria Matos Borges, PhD, Marilda Souza Goncalves

Blood (2018) 132 (Supplement 1): 3648.

https://doi.org/10.1182/blood-2018-99-117220

Published: 2018

Journal Articles

Aryl Hydrocarbon Receptor Antagonists Expand Adult Hematopoietic Stem Cells from Mobilized Peripheral Blood and Bone Marrow and Increase the Dose of CRISPR/Cas9 Gene-Edited NSG-Repopulating Cells

Megan D. Hoban, PhD, Kevin A. Goncalves, PhD, Jennifer L. Proctor, BS, Hillary L. Adams, MS, Sharon L. Hyzy, MS, Katia S. George, BA, Anthony E. Boitano, PhD, Michael P. Cooke, PhD

Blood (2017) 130 (Supplement 1): 3341.

https://doi.org/10.1182/blood.V130.Suppl_1.3341.3341

Published: 2017

Journal Articles

Characterization of a HBB -Locus Fetal Chromatin Domain Region during Adult Erythropoiesis

Li Liu, PhD, Xingguo Zhu, PhD, Alexander Yu, PhD, Betty S. Pace, MD

Blood (2017) 130 (Supplement 1): 2223.

https://doi.org/10.1182/blood.V130.Suppl_1.2223.2223

Published: 2017

Journal Articles

Early Loss of CREBBP Confers Malignant Stem Cell Properties on Lymphoid Progenitors

Brian J.P Huntly, MD PhD, Sarah Jayne Horton, BSc, PhD, George Giotopoulos, Haiyang Yun, MD PhD, Shabana Vohra, BSc, PhD, Olivia Sheppard, Bsc, PhD, Rachael Bashford-Rogers, PhD, Mamunur Rashid, PhD, Daniel Sasca, MD, Faisal Basheer, MBBChir, MA, Paolo Gallipoli, MD PhD, Jessica Okosun, Daniel James Hodson, MD PhD, Jude Fitzgibbon, Ming Du, David Adams

Blood (2016) 128 (22): 460.

https://doi.org/10.1182/blood.V128.22.460.460

Published: 2016

Journal Articles

GFI1 Snag Domain Methylation Directs LSD1 Recruitment to Control Transcription and Cell Fate Determination in Hematopoiesis

Matthew E Velinder, BS, Jason Singer, PhD, Jessica Meznarich, MD, Emily R Theisen, PhD, James Fulcher, BS, Christopher Tracy, PhD, Sarah Franklin, PhD, Sunil Sharma, MD, Michael E Engel, MD PhD

Blood (2015) 126 (23): 46.

https://doi.org/10.1182/blood.V126.23.46.46

Published: 2015

Journal Articles

Concurrent Inhibition of Beta-Catenin/CBP and FLT3 Strongly Suppresses c-Myc and Synergistically Induces Apoptosis in FLT3 Mutant AML Cells

Xuejie Jiang, Po Yee Mak, MPhil, Hong Mu, MD PhD, Weiguo Zhang, MD, PhD, Duncan Mak, BSc, MPhil, Peter Ruvolo, PhD, Teresa McQueen, Hongsheng Zhou, Jorge E. Cortes, Michael Andreeff, MD, PhD, Bing Z Carter

Blood (2015) 126 (23): 3685.

https://doi.org/10.1182/blood.V126.23.3685.3685

Published: 2015

Journal Articles

Pharmacologic increase in HIF1α enhances hematopoietic stem and progenitor homing and engraftment

Jennifer M. Speth, Jonathan Hoggatt, Pratibha Singh, Louis M. Pelus

Blood (2014) 123 (2): 203–207.

https://doi.org/10.1182/blood-2013-07-516336

Published: 2014

Includes: Supplemental data

Journal Articles

NPM-RAR Enhances NFκB Transcriptional Activity

Robert L. Redner, MD, Irina Abecassis, PhD, Elizabeth A. Rush, Anuja Chattopadhyay

Blood (2012) 120 (21): 5117.

https://doi.org/10.1182/blood.V120.21.5117.5117

Published: 2012

Journal Articles

the miR-99∼125 P olycistrons Promote Leukemogenesis in a Cell-Context Dependent Manner by Shifting the Balance Between TGFβ- and Wnt-Signaling

Stephan Emmrich, Mareike Rasche, Jennifer Schöning, Zhe Li, PhD, Axel Schambach, MD PhD, Dirk Reinhardt, MD, Jan-Henning Klusmann, MD

Blood (2012) 120 (21): 109.

https://doi.org/10.1182/blood.V120.21.109.109

Published: 2012

Journal Articles

MHC I–associated peptides preferentially derive from transcripts bearing miRNA response elements

Diana Paola Granados, Wafaa Yahyaoui, Céline M. Laumont, Tariq Daouda, Tara L. Muratore-Schroeder, Caroline Côté, Jean-Philippe Laverdure, Sébastien Lemieux, Pierre Thibault, Claude Perreault

Blood (2012) 119 (26): e181–e191.

https://doi.org/10.1182/blood-2012-02-412593

Published: 2012

Includes: Supplemental data

Journal Articles

Exploiting the NRF2/Antioxidant Response Element Signaling Pathway to Induce γ-Globin Gene Expression and HbF Production

Elizabeth R. Macari, BS, Rachel J. West, PhD, Christopher H. Lowrey, MD

Blood (2010) 116 (21): 2074.

https://doi.org/10.1182/blood.V116.21.2074.2074

Published: 2010

Journal Articles

Differential Engagement of the Unfolded Protein Response by Human and Porcine Factor VIII

Harrison C. Brown, BBA, Bagirath Gangadharan, MS, Christopher Doering, PhD

Blood (2010) 116 (21): 2224.

https://doi.org/10.1182/blood.V116.21.2224.2224

Published: 2010

Journal Articles

GATA2 is a New Predisposition Gene for Familial Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML)

Blood (2010) 116 (21): LBA-3.

https://doi.org/10.1182/blood.V116.21.LBA-3.LBA-3

Published: 2010

Journal Articles

Methylation Regulates Expression of Novel Splice Variant and Wild Type Transcripts of IRF8.

Era L. Pogosova-Agadjanyan, Hana Lee, Crystal K. Cummings, Soheil Meshinchi, MD, PhD, Jerald P. Radich, MD, Derek L. Stirewalt, MD

Blood (2010) 116 (21): 3634.

https://doi.org/10.1182/blood.V116.21.3634.3634

Published: 2010

Journal Articles

FOXO3a Mediates Both the Pro-Survival and Proapoptotic Effects of Glucocorticoids In Acute Lymphoblastic Leuekmia

Sandeep Gurbuxani, MBBS, PhD, Margo P Emont, Barbara L. Kee, PhD, Marcus E Peter, PhD

Blood (2010) 116 (21): 1822.

https://doi.org/10.1182/blood.V116.21.1822.1822

Published: 2010

Journal Articles

Systematic in vivo structure-function analysis of p300 in hematopoiesis

Erin A. Kimbrel, Madeleine E. Lemieux, Xiaobo Xia, Tina N. Davis, Vivienne I. Rebel, Andrew L. Kung

Blood (2009) 114 (23): 4804–4812.

https://doi.org/10.1182/blood-2009-04-217794

Published: 2009

Includes: Supplemental data

NARROW

A Gain of Function Mutation in the NSD2 Histone Methyltransferase Drives Glucocorticoid Resistance Via Blocking Receptor Auto-Induction and BIM/Bmf Expression in ALL

Bach1 Inhibitors Reduce Stasis in Townes Sickle Cell Mouse Model

Dependency of Spliceosomal Mutant MDS on Innate Immune Signaling

Ets1 Enhances Context-Dependent Notch1 Activity in T-Cell Leukemia

Hydroxyurea Exhibits Antioxidant Activity Via the Nrf2 Pathway- Antioxidant/Electrophile Response Element Regulated By p62/ SQSTM1

Aryl Hydrocarbon Receptor Antagonists Expand Adult Hematopoietic Stem Cells from Mobilized Peripheral Blood and Bone Marrow and Increase the Dose of CRISPR/Cas9 Gene-Edited NSG-Repopulating Cells

Characterization of a HBB -Locus Fetal Chromatin Domain Region during Adult Erythropoiesis

Early Loss of CREBBP Confers Malignant Stem Cell Properties on Lymphoid Progenitors

GFI1 Snag Domain Methylation Directs LSD1 Recruitment to Control Transcription and Cell Fate Determination in Hematopoiesis

Concurrent Inhibition of Beta-Catenin/CBP and FLT3 Strongly Suppresses c-Myc and Synergistically Induces Apoptosis in FLT3 Mutant AML Cells

Pharmacologic increase in HIF1α enhances hematopoietic stem and progenitor homing and engraftment

NPM-RAR Enhances NFκB Transcriptional Activity

the miR-99∼125 P olycistrons Promote Leukemogenesis in a Cell-Context Dependent Manner by Shifting the Balance Between TGFβ- and Wnt-Signaling

MHC I–associated peptides preferentially derive from transcripts bearing miRNA response elements

Exploiting the NRF2/Antioxidant Response Element Signaling Pathway to Induce γ-Globin Gene Expression and HbF Production

Differential Engagement of the Unfolded Protein Response by Human and Porcine Factor VIII

GATA2 is a New Predisposition Gene for Familial Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML)

Methylation Regulates Expression of Novel Splice Variant and Wild Type Transcripts of IRF8.

FOXO3a Mediates Both the Pro-Survival and Proapoptotic Effects of Glucocorticoids In Acute Lymphoblastic Leuekmia

Systematic in vivo structure-function analysis of p300 in hematopoiesis

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American Society of Hematology

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American Society of Hematology

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