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Journal Articles

Hepcidin, Soluble Transferrin Receptor, and Other Biomarkers of Iron Status Distributions in Healthy 2 Years Old Infants from a National Ambulatory Study in France

Anne-Sylvia Sacri, MD PhD, Thibaud Lefebvre, Pharm D.,PhD, Mariane De Montalembert, MD, Alain Bocquet, MD, Piotr Gembara, MD, Brigitte Pinçant, MD, Serge Hercberg, MD, PhD, Corinne Levy, MD, Amandine Ganon, Pharm D., Laurent Gouya, MD, PhD, Martin Chalumeau, MD, PhD

Blood (2019) 134 (Supplement_1): 4809.

https://doi.org/10.1182/blood-2019-128982

Published: 2019

Journal Articles

Enasidenib Drives Maturation of Human Erythroid Precursors Independently of IDH2

Ritika Dutta, BS, Tian Y Zhang, MD PhD, Thomas Koehnke, MD, Daniel Thomas, MD PhD, Eric Gars, MD, Melissa Stafford, Yusuke Nakauchi, MD PhD, Satinder Kaur, BS, Raymond Yin, Anupama Narla, MD, Ravindra Majeti, MD PhD

Blood (2019) 134 (Supplement_1): 540.

https://doi.org/10.1182/blood-2019-124551

Published: 2019

Journal Articles

Targeted Therapy of Acute Chest Syndrome with Recombinant Heme Oxygenase-1 Revealed By the Resistance of Young Transgenic Sickle Cell Mice to Heme-Induced Acute Lung Injury

Rimi Hazra, Samit Ghosh, Bethany Flage, Matthew Crouthamel, Clark Pan, Xiuxia Sun, Bohong Zhang, Joseph Sypek, Solomon Fiifi Ofori-Acquah

Blood (2019) 134 (Supplement_1): 74.

https://doi.org/10.1182/blood-2019-127198

Published: 2019

Journal Articles

HO-1 Promotes Resistance to EZH2 Inhibitor through the Prb-E2F Pathway: Corelated with the Conversion of Myelodysplastic Syndrome to Acute Myeloid Leukemia

Zhengchang He, Jishi Wang, PhD

Blood (2019) 134 (Supplement_1): 5401.

https://doi.org/10.1182/blood-2019-131573

Published: 2019

Journal Articles

Cytoreductive Treatment in 'Real Life' - Interim-Analysis of 434 Polycythemia Vera Patients in Germany

Carl C. Crodel, Kathleen Jentsch-Ulrich, MD, Lutz Jacobasch, Philipp Kiewe, Jens Kisro, Jörg Lipke, Siegfried W. Prenninger, Marcel Reiser, Regine Wunschel, Andreas Hochhaus, MD, Florian H. Heidel

Blood (2019) 134 (Supplement_1): 1672.

https://doi.org/10.1182/blood-2019-122681

Published: 2019

Journal Articles

Patrolling Monocytes Scavenge Endothelial Adherent Sickle Red Blood Cells in Sickle Cell Disease

Yunfeng Liu, PhD, Hui Zhong, PhD, Weili Bao, MS, Avital Mendelson, PhD, Xiuli An, MD PhD, Patricia Shi, MD, Stella T. Chou, MD, Deepa Manwani, MD, Karina Yazdanbakhsh, PhD

Blood (2018) 132 (Supplement 1): 744.

https://doi.org/10.1182/blood-2018-99-118527

Published: 2018

Journal Articles

Free Heme Induces a Heme Importer, Heme Catabolism and an Angiogenic Factor in Multiple Organs in Mice: Implications for Organ-Specific Response to Intravascular Hemolysis

Oluwabukola Gbotosho, BSc, MSc, PhD, Maria G Kapetanaki, PhD, Yu Lin, Frances Weidert, MSc, Solomon Fiifi Ofori-Acquah, PhD, Gregory J. Kato, MD

Blood (2017) 130 (Supplement 1): 3468.

https://doi.org/10.1182/blood.V130.Suppl_1.3468.3468

Published: 2017

Journal Articles

The Role of TCA Cycle Compounds in Erythroid Heme Synthesis and Its Regulation During an Inflammatory Response

Jason R. Marcero, BS, Joseph S. Burch, PhD, John D. Phillips, PhD, James E. Cox, PhD, Laurie K. Jackson, PhD, Harry A. Dailey, PhD

Blood (2017) 130 (Supplement 1): 3473.

https://doi.org/10.1182/blood.V130.Suppl_1.3473.3473

Published: 2017

Journal Articles

Digital PCR Assay to Assess the Alternative Splicing and Absolute Ferrochelatase Expression

Valentina Brancaleoni, MSc, Francesca Granata, MSc, Silvia Fustinoni, PhD, Giovanna Graziadei, MD, Maria Domenica Cappellini, MD, Elena Di Pierro, PhD

Blood (2017) 130 (Supplement 1): 3474.

https://doi.org/10.1182/blood.V130.Suppl_1.3474.3474

Published: 2017

Journal Articles

Heme Synthesis Is Inhibited in Erythroid Cells Derived from Beta-Thalassemic Mice

Daniel Garcia dos Santos, PhD, Amel Hamdi, PhD, Prem Ponka, MD PhD

Blood (2017) 130 (Supplement 1): 3494.

https://doi.org/10.1182/blood.V130.Suppl_1.3494.3494

Published: 2017

Journal Articles

Heme Regulates the Expression in Erythroblasts of Placenta Growth Factor, a Contributor to Pulmonary Hypertension in Sickle Cell Disease, through the Oxidant Response Transcription Factor NRF2

Maria G Kapetanaki, PhD, Oluwabukola Gbotosho, BSc, MSc, PhD, Deva Sharma, MD MS, Schrott Valerie, MS, Frances Weidert, MSc, Solomon Fiifi Ofori-Acquah, PhD, Grant C. Bullock, MD PhD, Gregory J. Kato, MD

Blood (2017) 130 (Supplement 1): 3496.

https://doi.org/10.1182/blood.V130.Suppl_1.3496.3496

Published: 2017

Journal Articles

Molecular and Pharmacological Inhibition of ATP Binding Cassette Transporter ABCB6 Decreases Chemoresistance in Acute Myeloid Leukemia

Sreeja Karathedath, PhD, Raveen Stephen Stallon Illangeswaran, M.Sc.,, Saswati Das, MSc., Bharathi M Rajamani, Srujan Kumar Marepally, M.Sc., PhD, Partha Kasturi, PhD, Vikram Mathews, MD DM, Shaji Ramachandran Velayudhan, M.Sc., PhD, Poonkuzhali Balasubramanian, MSc, PhD

Blood (2017) 130 (Supplement 1): 1254.

https://doi.org/10.1182/blood.V130.Suppl_1.1254.1254

Published: 2017

Journal Articles

HEME Degradation Enzyme Biliverdin IXb Reductase Is Required for Stem Cell Glutamine Metabolism

Zongdong Li, PhD, Wadie F. Bahou, MD

Blood (2017) 130 (Supplement 1): 3763.

https://doi.org/10.1182/blood.V130.Suppl_1.3763.3763

Published: 2017

Journal Articles

Free Iron in Sera of Patients with Sickle Cell Disease Contributes to the Release of Neutrophil Extracellular Traps

Kristof Van Avondt, PhD, Marein Schimmel, Ingrid Bulder, Robin van Bruggen, PhD, Bart J. Biemond, MD PhD, Brenda M. Luken, PhD, Sacha S. Zeerleder, MD PhD

Blood (2016) 128 (22): 161.

https://doi.org/10.1182/blood.V128.22.161.161

Published: 2016

Journal Articles

Erythropoietin Signaling Regulates Heme Biosynthesis

Jacky Chung, PhD, Johannes G. Wittig, Alireza Ghamari, Manami Maeda, MD, PhD, Harvey Lodish, PhD, Daniel E. Bauer, MD, PhD, Stuart H. Orkin, MD, Alan B. Cantor, MD, PhD, Takahiro Maeda, MD PhD, Harry A. Dailey, PhD, Barry H. Paw, MD, PhD

Blood (2016) 128 (22): 543.

https://doi.org/10.1182/blood.V128.22.543.543

Published: 2016

Journal Articles

A Dominant Mutation in Mitochondrial Unfoldase CLPX Results in Erythropoietic Protoporphyria

Yvette Y Yien, PhD, Gael Nicolas, PhD, Lisa van der Vorm, Laurent Gouya, MD PhD, Hector Begonia, Martin Kafina, Jean-Charles Deybach, MD PhD, Tania Baker, PhD, Julia Kardon, PhD, John D. Phillips, PhD, Hervé Puy, MD PhD, Barry H. Paw, MD, PhD

Blood (2016) 128 (22): 77.

https://doi.org/10.1182/blood.V128.22.77.77

Published: 2016

Journal Articles

Endosome-Mitochondria Interface Controls Intracellular Iron Trafficking in Erythroid Cells

Amel Hamdi, PhD, Daniel Garcia-Santos, PhD, Tariq Roshan, MD, Alex Sheftel, PhD, Prem Ponka, MD PhD FCMA

Blood (2016) 128 (22): 75.

https://doi.org/10.1182/blood.V128.22.75.75

Published: 2016

Journal Articles

Haptoglobin and Hemopexin Infusion Efficiently Activates the Nrf2/HO-1 Axis and Inhibits Inflammation and Vaso-Occlusion in Murine Sickle Cell Disease

John D Belcher, PhD, Chunsheng Chen, PhD, Julia Nguyen, BS, Fuad Abdulla, DVM, Phong Nguyen, BS, Hao Nguyen, Ping Zhang, PhD, Nathan Brinkman, Gregory M Vercellotti, MD

Blood (2016) 128 (22): 2477.

https://doi.org/10.1182/blood.V128.22.2477.2477

Published: 2016

Journal Articles

Heme Oxygenase 1 Inhibition Reverses Anemia in β-Thalassemia Mice

Daniel Garcia-Santos, PhD, Amel Hamdi, PhD, Zuzana Zidova, MSc, Monika Horvathova, PhD, Prem Ponka, MD PhD FCMA

Blood (2016) 128 (22): 2462.

https://doi.org/10.1182/blood.V128.22.2462.2462

Published: 2016

Journal Articles

Targeting the NRF2/HO-1 Antioxidant Pathway with Consequences for Notch Signaling in FLT3-ITD Positive AML: A Novel Therapeutic Approach

Marisa J Hornbaker, B.S., Mary E Irwin, PhD, LaNisha Patterson, B.S., Shelley M Herbrich, MS, Patrick Zweidler-McKay, MD PhD, Joya Chandra, PhD

Blood (2015) 126 (23): 2470.

https://doi.org/10.1182/blood.V126.23.2470.2470

Published: 2015

NARROW

Hepcidin, Soluble Transferrin Receptor, and Other Biomarkers of Iron Status Distributions in Healthy 2 Years Old Infants from a National Ambulatory Study in France

Enasidenib Drives Maturation of Human Erythroid Precursors Independently of IDH2

Targeted Therapy of Acute Chest Syndrome with Recombinant Heme Oxygenase-1 Revealed By the Resistance of Young Transgenic Sickle Cell Mice to Heme-Induced Acute Lung Injury

HO-1 Promotes Resistance to EZH2 Inhibitor through the Prb-E2F Pathway: Corelated with the Conversion of Myelodysplastic Syndrome to Acute Myeloid Leukemia

Cytoreductive Treatment in 'Real Life' - Interim-Analysis of 434 Polycythemia Vera Patients in Germany

Patrolling Monocytes Scavenge Endothelial Adherent Sickle Red Blood Cells in Sickle Cell Disease

Free Heme Induces a Heme Importer, Heme Catabolism and an Angiogenic Factor in Multiple Organs in Mice: Implications for Organ-Specific Response to Intravascular Hemolysis

The Role of TCA Cycle Compounds in Erythroid Heme Synthesis and Its Regulation During an Inflammatory Response

Digital PCR Assay to Assess the Alternative Splicing and Absolute Ferrochelatase Expression

Heme Synthesis Is Inhibited in Erythroid Cells Derived from Beta-Thalassemic Mice

Heme Regulates the Expression in Erythroblasts of Placenta Growth Factor, a Contributor to Pulmonary Hypertension in Sickle Cell Disease, through the Oxidant Response Transcription Factor NRF2

Molecular and Pharmacological Inhibition of ATP Binding Cassette Transporter ABCB6 Decreases Chemoresistance in Acute Myeloid Leukemia

HEME Degradation Enzyme Biliverdin IXb Reductase Is Required for Stem Cell Glutamine Metabolism

Free Iron in Sera of Patients with Sickle Cell Disease Contributes to the Release of Neutrophil Extracellular Traps

Erythropoietin Signaling Regulates Heme Biosynthesis

A Dominant Mutation in Mitochondrial Unfoldase CLPX Results in Erythropoietic Protoporphyria

Endosome-Mitochondria Interface Controls Intracellular Iron Trafficking in Erythroid Cells

Haptoglobin and Hemopexin Infusion Efficiently Activates the Nrf2/HO-1 Axis and Inhibits Inflammation and Vaso-Occlusion in Murine Sickle Cell Disease

Heme Oxygenase 1 Inhibition Reverses Anemia in β-Thalassemia Mice

Targeting the NRF2/HO-1 Antioxidant Pathway with Consequences for Notch Signaling in FLT3-ITD Positive AML: A Novel Therapeutic Approach

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American Society of Hematology

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American Society of Hematology

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