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Journal Articles

Genetic disruption of N-Ras G12D palmitoylation perturbs hematopoiesis and prevents myeloid transformation in mice

Noemi A. Zambetti, Ari J. Firestone, Jarrett R. Remsberg, Benjamin J. Huang, Jasmine C. Wong, Amanda M. Long, Marina Predovic, Radu M. Suciu, Anagha Inguva, Scott C. Kogan, Kevin M. Haigis, Benjamin F. Cravatt, Kevin Shannon

Blood (2020) 135 (20): 1772–1782.

https://doi.org/10.1182/blood.2019003530

Published: 2020

Includes: Supplemental data

Journal Articles

Innate Immune Signaling Suppresses Acute Leukemia By Modifying MYC Oncogenic Activity

Tomoya Muto, MD PhD, Maria Guillamot, PhD, Jing Fang, MD PhD, Luna Zea Redondo, MS, Kwangmin Choi, PhD, Yixiao Gong, MSc, Callum S Walker, MSc, Kathleen Hueneman, Lyndsey C Bolanos, BSc, Laura Barreyro, PhD, Lynn Lee, MD, Kenneth D Greis, PhD, Alireza Khodadadi-Jamayran, M.Sc., Amaia Lujambio, PhD, Scott W. Lowe, PhD, Iannis Aifantis, PhD, Daniel T. Starczynowski, PhD

Blood (2019) 134 (Supplement_1): 727.

https://doi.org/10.1182/blood-2019-121423

Published: 2019

Journal Articles

The Role of Calreticulin in Normal Hematopoiesis and Neoplastic Hematopoiesis of Myeloproliferative Neoplasms

Kotaro Shide, MD PhD, Takuro Kameda, MD PhD, Ayako Kamiunten, MD, Yoshinori Ozono, MD, Yuki Tahira, MD, Masaaki Sekine, MD, Masaya Ono, MD PhD, Takako Yokomizo, PhD, Sho Kubota, Keiichi Akizuki, MD, Yoko Kubuki, MD PhD, Tomonori Hidaka, MD, Goro Sashida, MD PhD, Kazuya Shimoda, MD PhD

Blood (2019) 134 (Supplement_1): 309.

https://doi.org/10.1182/blood-2019-130034

Published: 2019

Journal Articles

Shared and Distinctive Ultrastructural Abnormalities Expressed By Megakaryocytes in Bone Marrow and Spleen from Patients with Primary Myelofibrosis

Maria Zingariello, PhD, Vittorio Rosti, MD, Alessandro M. Vannucchi, MD, Paola Guglielmelli, MD PhD, Claudio Bardelli, PhD, Maria Mazzarini, Rosa Alba Rana, Giovanni Barosi, Anna Rita Rita Migliaccio, PhD

Blood (2019) 134 (Supplement_1): 4209.

https://doi.org/10.1182/blood-2019-123140

Published: 2019

Journal Articles

O-Glcnacylation Is Essential for Erythropoiesis

Matthew P Parker, BS, Halyna Fedosyuk, MS, Lesya V Novikova, PhD, Zhen Zhang, PhD, Chad Slawson, PhD, Kenneth R Peterson, PhD

Blood (2019) 134 (Supplement_1): 2218.

https://doi.org/10.1182/blood-2019-129468

Published: 2019

Journal Articles

Leukemogenic Functions of Mutant ASXL1 Are Regulated By CDK-Mediated Phosphorylation

Shuhei Asada, MD PhD, Susumu Goyama, MD PhD, Reina Takeda, MD, Keita Yamamoto, MD, Hiroko Kozuka-Hata, PhD, Masaaki Oyama, PhD, Daichi Inoue, MD PhD, Hiroaki Honda, MD PhD, Toshio Kitamura, MD PhD

Blood (2019) 134 (Supplement_1): 731.

https://doi.org/10.1182/blood-2019-125959

Published: 2019

Journal Articles

SIRT3 Sumoylation Contributes to Chemoresistance in AML

Jiao MA, PhD, Bin Liu, MSc, Dan Yu, BSc, Wayne Tam, MD PhD, Jianmin Yang, PhD, Jinke Cheng, PhD

Blood (2018) 132 (Supplement 1): 3929.

https://doi.org/10.1182/blood-2018-99-110898

Published: 2018

Journal Articles

Hematopoietic Stem and Progenitor Cell Proliferation and Differentiation Requires the Trithorax Protein Ash2l In Vivo

Nicolas Chatain, PhD, Juliane Lüscher-Firzlaff, Chao-Chung Kuo, Agnieszka Bochyńska, Andrea Ullius, Bernd Denecke, Ivan Costa, Steffen Koschmieder, MD, Bernhard Lüscher

Blood (2018) 132 (Supplement 1): 2566.

https://doi.org/10.1182/blood-2018-99-115950

Published: 2018

Journal Articles

Erythrocyte Cytochrome b Reductase 1 Protein Levels and Structure in Sickle Cell Patients

Richard Kulmacz, PhD, Hamidreza Farzaneh, MS, Kathryn L McElhinney, BS, Jose M. Rodriguez, BS, Nicole C. Thomason, BS, Ehsan Irajizad, BE, Vladimir Berka, PhD, Wen Liu, PhD, Modupe Idowu, MD, Harinder S. Juneja, MD

Blood (2018) 132 (Supplement 1): 3654.

https://doi.org/10.1182/blood-2018-99-119885

Published: 2018

Journal Articles

Mutations in the RNA Splicing Factor SF3B1 Promote Transformation through MYC Stabilization

Akihide Yoshimi, MD, Zhaoqi Liu, PhD, Wang Jiguang, Hana Cho, MSc, Stanley C Lee, PhD, Michelle Ki, BSc, Lillian E Bitner, BSc, Timothy Chu, Anthony R Mato, MD, Peter P. Ruvolo, PhD, Giulia Fabbri, Laura Pasqualucci, MD, Raul Rabadan, PhD, Omar I Abdel-Wahab, MD

Blood (2018) 132 (Supplement 1): 882.

https://doi.org/10.1182/blood-2018-99-110328

Published: 2018

Journal Articles

Comparison of the Functional Characteristics and Post-Translational Modifications of Commercial Factor VIII Products

Guido Kohla, PhD, Larisa Belyanskaya, PhD, Maya Tiemeyer, PhD, Thole Züchner, PhD, Irena Knappik, PhD, Julia Rosenlöcher, PhD

Blood (2017) 130 (Supplement 1): 2362.

https://doi.org/10.1182/blood.V130.Suppl_1.2362.2362

Published: 2017

Journal Articles

Altered Expression of Neddylation Pathway Proteins in Myelodysplastic Syndromes

Fatemeh Majidi, MD, Judith Neukirchen, MD, Simon Brille, Iris Fey, BSc., Frank Neumann, MDPhD, Allison Berger, PhD, Ron-Patrick Cadeddu, PhD, Martina Rudelius, MD, Ulrich Germing, MD, Rainer Haas, MD, Norbert Gattermann, MD

Blood (2017) 130 (Supplement 1): 5298.

https://doi.org/10.1182/blood.V130.Suppl_1.5298.5298

Published: 2017

Journal Articles

N-Myristoyltransferase 2 (NMT2) Protein Levels Predict Survival in Acute Myeloid Leukemia (AML): A Novel Prognostic Biomarker

Ryan J Stubbins, MDMSc, Zoulika Zak, Aishwarya Iyer, Megan Yap, Krista Vincent, Lynne M Postovit, MD, John R Mackey, MD, Artur J Szkotak, MD PhD, Lalit Saini, MD, Luc G Berthiaume, PhD, Joseph M. Brandwein, MD FRCPC

Blood (2017) 130 (Supplement 1): 3914.

https://doi.org/10.1182/blood.V130.Suppl_1.3914.3914

Published: 2017

Journal Articles

RNA Sequencing Data-Driven Dissection of Human Plasma Cell Differentiation Reveals New Potential Transcription Regulators

Alboukadel Kassambara, PhD, Laurie Herviou, Michel Jourdan, Coraline Thibaut, Veronika Vikova, Olivier Elemento, PhD, Jerome Moreaux, PhD

Blood (2017) 130 (Supplement 1): 4382.

https://doi.org/10.1182/blood.V130.Suppl_1.4382.4382

Published: 2017

Journal Articles

Silencing TG2 in Acute Myeloid Leukemia. Possible Role of TG2 in Microenvironment-Mediated Chemoresistance

Rodrigo Omar Jacamo, PhD, Qi Zhang, MD PhD, Teresa McQueen, MS, Richard Eric Davis, MD, Marina Konopleva, MD PhD, Michael Andreeff, MD PhD

Blood (2016) 128 (22): 5087.

https://doi.org/10.1182/blood.V128.22.5087.5087

Published: 2016

Journal Articles

Novel Sites of Gamma Carboxylation in Human Factor VII

Emily M Wilkerson, Barbara Bates, Kraig T Kumfer, Nicholas M Riley, Brad S Schwartz, Joshua J Coon

Blood (2016) 128 (22): 3759.

https://doi.org/10.1182/blood.V128.22.3759.3759

Published: 2016

Journal Articles

APT1-Mediated Cross-Talk Between Palmitoylation and Phosphorylation Events of the BCR Pathway Sensitizes CLL Cells Towards BCR-Associated Kinase Inhibitors

Valeska Berg, PhD, Dunja Baatout, M.Sc., Clemens Wendtner, MD, Michael Hallek, Lukas P. Frenzel, MD

Blood (2016) 128 (22): 4361.

https://doi.org/10.1182/blood.V128.22.4361.4361

Published: 2016

Journal Articles

Unravelling the Complexities of Hedgehog Mediated Signal Transduction in Acute Myeloid Leukaemia and Normal Haematopoiesis

Victoria Campbell, BSc hons, MBBS, MRCP, FRCPath, Anuradha Tarafdar, PhD, Edwina Dobbin, PhD, Gillian A. Horne, BSc hons, MBChB, MRCP, MRes, Laura Park, PhD, Colin Nixon, John R. Goodlad, MD FRCPath, Helen Wheadon, PhD, Mhairi Copland, PhD BSc, MB, ChB, MRCP, FRCPath

Blood (2016) 128 (22): 2881.

https://doi.org/10.1182/blood.V128.22.2881.2881

Published: 2016

Journal Articles

Mpl Gain-of-Function Mutations Can be Classified By Differential Subcellular Processing, Molecular Mechanisms, Mode of Inheritance and Clinical Impact

Clemens Stockklausner, MD, Christin Maria Duffert, Ziwei Zhou, Anne Christine Klotter, Isabelle Nadine Kuhlee, Andreas E Kulozik, MDPhD

Blood (2015) 126 (23): 1634.

https://doi.org/10.1182/blood.V126.23.1634.1634

Published: 2015

Journal Articles

EPO Modulation of Thioredoxin Interacting Protein (TXNIP), and Key Roles for TXNIP during EPO-Dependent Human Erythroid Progenitor Cell Growth and Development

Don M. Wojchowski, PhD, Edward Jachimowicz, Ruth Asch, Nicole M. Rainville

Blood (2015) 126 (23): 2129.

https://doi.org/10.1182/blood.V126.23.2129.2129

Published: 2015

NARROW

Genetic disruption of N-Ras G12D palmitoylation perturbs hematopoiesis and prevents myeloid transformation in mice

Innate Immune Signaling Suppresses Acute Leukemia By Modifying MYC Oncogenic Activity

The Role of Calreticulin in Normal Hematopoiesis and Neoplastic Hematopoiesis of Myeloproliferative Neoplasms

Shared and Distinctive Ultrastructural Abnormalities Expressed By Megakaryocytes in Bone Marrow and Spleen from Patients with Primary Myelofibrosis

O-Glcnacylation Is Essential for Erythropoiesis

Leukemogenic Functions of Mutant ASXL1 Are Regulated By CDK-Mediated Phosphorylation

SIRT3 Sumoylation Contributes to Chemoresistance in AML

Hematopoietic Stem and Progenitor Cell Proliferation and Differentiation Requires the Trithorax Protein Ash2l In Vivo

Erythrocyte Cytochrome b Reductase 1 Protein Levels and Structure in Sickle Cell Patients

Mutations in the RNA Splicing Factor SF3B1 Promote Transformation through MYC Stabilization

Comparison of the Functional Characteristics and Post-Translational Modifications of Commercial Factor VIII Products

Altered Expression of Neddylation Pathway Proteins in Myelodysplastic Syndromes

N-Myristoyltransferase 2 (NMT2) Protein Levels Predict Survival in Acute Myeloid Leukemia (AML): A Novel Prognostic Biomarker

RNA Sequencing Data-Driven Dissection of Human Plasma Cell Differentiation Reveals New Potential Transcription Regulators

Silencing TG2 in Acute Myeloid Leukemia. Possible Role of TG2 in Microenvironment-Mediated Chemoresistance

Novel Sites of Gamma Carboxylation in Human Factor VII

APT1-Mediated Cross-Talk Between Palmitoylation and Phosphorylation Events of the BCR Pathway Sensitizes CLL Cells Towards BCR-Associated Kinase Inhibitors

Unravelling the Complexities of Hedgehog Mediated Signal Transduction in Acute Myeloid Leukaemia and Normal Haematopoiesis

Mpl Gain-of-Function Mutations Can be Classified By Differential Subcellular Processing, Molecular Mechanisms, Mode of Inheritance and Clinical Impact

EPO Modulation of Thioredoxin Interacting Protein (TXNIP), and Key Roles for TXNIP during EPO-Dependent Human Erythroid Progenitor Cell Growth and Development

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American Society of Hematology

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ASH Publications

American Society of Hematology

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