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Noemi A. Zambetti
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Journal Articles

Genetic disruption of N-Ras G12D palmitoylation perturbs hematopoiesis and prevents myeloid transformation in mice

Noemi A. Zambetti, Ari J. Firestone, Jarrett R. Remsberg, Benjamin J. Huang, Jasmine C. Wong, Amanda M. Long, Marina Predovic, Radu M. Suciu, Anagha Inguva, Scott C. Kogan, Kevin M. Haigis, Benjamin F. Cravatt, Kevin Shannon
Journal: Blood
Blood (2020) 135 (20): 1772–1782.
https://doi.org/10.1182/blood.2019003530
Published: 2020
Includes: Supplemental data
Journal Articles

Genetic Validation of the Palmitoylation/Depalmitoylation Cycle As a Drug Target in NRAS Mutant Hematologic Malignancies In Vivo

Noemi A. Zambetti, PhD, Ari J. Firestone, PhD, Jasmine C. Wong, PhD, Amanda Long, BA, Anagha Inguva, BA, Radu M. Suciu, B.Sc., Benjamin F. Cravatt, PhD, Kevin M. Haigis, PhD, Kevin M. Shannon, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1221.
https://doi.org/10.1182/blood.V130.Suppl_1.1221.1221
Published: 2017
Journal Articles

Inflammatory Niche Signalling Drives Genotoxic Stress in Hematopoietic Stem Cells and Predicts Leukemic Evolution in Human Leukemia Predisposition Syndromes

Si Chen, MSCs, Noemi A. Zambetti, PhD, Zhen Ping, MSCs, Keane Kenswil, MSCs, Maria Mylona, PhD, Mathijs A. Sanders, PhD, Remco Hoogenboezem, MSc, Eric Bindels, PhD, Maria Adisty, Paulina M. H. van Strien, B.Sc., Cindy van der Leije, Theresia M Westers, PhD, Eline MP Cremers, MD, Chiara Milanese, PhD, Pier Mastroberardino, PhD, Johannes van Leeuwen, PhD, Bram Van der Eerden, PhD, Ivo Touw, PhD, Kuijpers Taco, Roland Kanaar, PhD, Arjan van der Loosdrecht, MD PhD, Thomas Vogl, PhD, Marc H.G.P. Raaijmakers, MD PhD
Journal: Blood
Blood (2016) 128 (22): 428.
https://doi.org/10.1182/blood.V128.22.428.428
Published: 2016
Journal Articles

Deletion of Sbds from Hematopoietic Progenitors Causes Neutropenia in a Mouse Model of Shwachman-Diamond Syndrome By Specifically Blocking Myeloid Lineage Progression at Late Differentiation Stages

Noemi A. Zambetti, Paulina M.H. Van Strien, Marijke G. Valkhof, Maria N. Adisty, Eric M. J. Bindels, PhD, Remco M. Hoogenboezem, Mathijs A. Sanders, MSc, Johanna M. Rommens, PhD, Ivo P. Touw, PhD, Marc H.G.P. Raaijmakers, MD PhD
Journal: Blood
Blood (2014) 124 (21): 355.
https://doi.org/10.1182/blood.V124.21.355.355
Published: 2014