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Journal Articles

Identification of Novel Synthetic Lethal Partners of NAMPT Inhibitor By CRISPR-Cas9 Screens in Acute Myeloid Leukemia

Pu Zhang, Lindsey Brinton, PhD, James S. Blachly, MD, John C. Byrd, MD, Rosa Lapalombella, PhD

Blood (2019) 134 (Supplement_1): 2072.

https://doi.org/10.1182/blood-2019-129036

Published: 2019

Journal Articles

Net Clinical Benefit of Low Dose Rivaroxaban in Coronary Heart Disease: A Systematic Review and Meta-Analysis

Muhammad Zain Farooq, MD MBBS, Muhammad Saad Farooq, MBBS, Saira Farid, MD, Talha Aijaz, MD, Ishaan Vohra, MD, Vatsala Katiyar, MD, Ankit Mangla, MBBS,MD

Blood (2019) 134 (Supplement_1): 3662.

https://doi.org/10.1182/blood-2019-121899

Published: 2019

Journal Articles

Safety and Antithrombotic Efficacy of the Recombinant Protein C Activator AB002 (E-WE Thrombin) in End Stage Renal Disease Patients on Chronic Hemodialysis

Norah G Verbout, PhD, Christina U Lorentz, PhD, Brandon D Markway, PhD, Joseph J Shatzel, MD, Erik I Tucker, PhD, Andras Gruber, MD

Blood (2019) 134 (Supplement_1): 2433.

https://doi.org/10.1182/blood-2019-124999

Published: 2019

Journal Articles

HDAC8 Maintain Cytoskeleton Integrity Via Homologous Recombination and Represent a Novel Therapeutic Target in Multiple Myeloma

Zuzana Chyra, PhD, Maria Gkotzamanidou, MD PhD, Masood A. Shammas, PhD, Vassilis L. Souliotis, PhD, Yan Xu, MD, Mehmet K. Samur, PhD, Aaron B. Beeler, PhD, Roman Hajek, MD, Mariateresa Fulciniti, PhD, Nikhil C. Munshi, MD

Blood (2019) 134 (Supplement_1): 4385.

https://doi.org/10.1182/blood-2019-130700

Published: 2019

Journal Articles

A Quantitative Systems Pharmacology (QSP) Model to Predict Receptor Occupancy of Bruton's Tyrosine Kinase (BTK) Inhibitors in Peripheral Blood Mononuclear Cells, Bone Marrow and Lymph Nodes of Patients with B-Cell Malignancies

Srikumar Sahasranaman, PhD, Oleg Demin, Jr., Dmitry Shchelokov, Veronika Musatova, Nageshwar Budha, PhD, Ying Ou, PhD

Blood (2019) 134 (Supplement_1): 1289.

https://doi.org/10.1182/blood-2019-129133

Published: 2019

Journal Articles

Design and characterization of α1-antitrypsin variants for treatment of contact system–driven thromboinflammation

Steven de Maat, Wariya Sanrattana, Reiner K. Mailer, Naomi M. J. Parr, Martin Hessing, Robert M. Koetsier, Joost C. M. Meijers, Gerard Pasterkamp, Thomas Renné, Coen Maas

Blood (2019) 134 (19): 1658–1669.

https://doi.org/10.1182/blood.2019000481

Published: 2019

Includes: Supplemental data

Journal Articles

A Direct Oral Anticoagulant Edoxaban Enhanced Fibrinolysis Via Inhibition of Thrombin-Activatable Fibrinolysis Inhibitor Activation and Enhancement of Plasmin Generation in Human Plasma

Yoshiyuki Morishima, PhD, Yuko Honda, Taketoshi Furugohri, PhD

Blood (2018) 132 (Supplement 1): 3786.

https://doi.org/10.1182/blood-2018-99-109724

Published: 2018

Journal Articles

Rivaroxaban Thromboprophylaxis in High-Risk Ambulatory Cancer Patients Receiving Systemic Therapy: Results of a Randomized Clinical Trial (CASSINI)

Blood (2018) 132 (Supplement 1): LBA-1.

https://doi.org/10.1182/blood-2018-120738

Published: 2018

Journal Articles

Efficacy of Anti-TFPI Antibody PF-06741086 Alone and in Combination with Activated Prothrombin Complex Concentrates in Mouse Hemophilia a Bleeding Model

Amey Barakat, Reema Jasuja, PhD, John E. Murphy, PhD, Debra D Pittman, MS

Blood (2018) 132 (Supplement 1): 2460.

https://doi.org/10.1182/blood-2018-99-118431

Published: 2018

Journal Articles

Restrictive Versus Liberal Red Blood Cell Transfusion for Cardiac Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Babikir Kheiri, MD, Ahmed Abdalla, MD, Mohamed Osman, MD, Tarek Haykal, MD, Sai Chintalapati, MD, James Cranford, PhD, Sahar Ahmed, MBBS, Mustafa Hassan, MD, Ghassan Bachuwa, MD MHSA, MS, Deepak L. Bhatt, MD MPH

Blood (2018) 132 (Supplement 1): 3821.

https://doi.org/10.1182/blood-2018-99-111993

Published: 2018

Journal Articles

Histone Deacetylase Inhibitors Downregulate CCR4 Expression and Decrease Mogamulizumab Efficacy in CCR4-Positive Mature T-Cell Lymphomas

Akihiro Kitadate, MD, Sho Ikeda, MD, Fumito Abe, MD PhD, Naoto Takahashi, MD PhD, Norio Shimizu, PhD, Kosei Matsue, MD PhD, Hiroyuki Tagawa, MD PhD

Blood (2017) 130 (Supplement 1): 720.

https://doi.org/10.1182/blood.V130.Suppl_1.720.720

Published: 2017

Journal Articles

Phenotype Does Not Always Equal Function: HDAC Inhibitors and UM171, but Not SR1, Lead to Rapid Upregulation of CD90 on Non-Engrafting CD34+CD90-Negative Human Cells

Kevin A. Goncalves, PhD, Megan D. Hoban, Jennifer L. Proctor, BS, Hillary L. Adams, MS, Sharon L. Hyzy, MS, Anthony E. Boitano, PhD, Michael P. Cooke, PhD

Blood (2017) 130 (Supplement 1): 659.

https://doi.org/10.1182/blood.V130.Suppl_1.659.659

Published: 2017

Journal Articles

Design and characterization of an APC-specific serpin for the treatment of hemophilia

Stéphanie G. I. Polderdijk, Ty E. Adams, Lacramioara Ivanciu, Rodney M. Camire, Trevor P. Baglin, James A. Huntington

Blood (2017) 129 (1): 105–113.

https://doi.org/10.1182/blood-2016-05-718635

Published: 2017

Includes: Supplemental data

Journal Articles

A Drug-Drug Interaction Study of Ibrutinib with Moderate and Strong CYP3A Inhibitors in Patients with B-Cell Malignancy

Jan de Jong, PhD, Peter Hellemans, MD, Severijn De Wilde, Daniel Patricia, Tara Masterson, Georgii Manikhas, MD PhD, Alexander Myasnikov, MD PhD, Dzhelil Osmanov, MD, Raul Cordoba, MD PhD, Carlos Panizo, Loeckie de Zwart, PhD, Jan Snoeys, PhD, Vijay Chauhan, PhD, James Jiao, PhD, Juthamas Sukbuntherng, PhD, Daniele Ouellet, PhD

Blood (2016) 128 (22): 3964.

https://doi.org/10.1182/blood.V128.22.3964.3964

Published: 2016

Journal Articles

An Open-Label, Sequential-Design Drug Interaction Study of the Effects of Omeprazole on the Pharmacokinetics of Ibrutinib in Healthy Adults

Jan de Jong, PhD, Peter Hellemans, MD, James Jiao, PhD, Juthamas Sukbuntherng, PhD, Daniele Ouellet, PhD

Blood (2016) 128 (22): 1588.

https://doi.org/10.1182/blood.V128.22.1588.1588

Published: 2016

Journal Articles

Spatially Organized Structure of Coronary Thrombus in Acute Myocardial Infarction

Jan E. Dyr, prof., PhD, MSc., DSc., Tomas Riedel, PhD, MSc., Jana Stikarova, PhD, MSc., Jiri Suttnar, PhD, MSc., Jaroslav Cermak, MD PhD, Roman Kotlin, PhD, MSc., Martin Hajsl, MD, Petr Tousek, MD PhD, Viktor Kocka, MD PhD, Martin Maly, MD PhD

Blood (2016) 128 (22): 716.

https://doi.org/10.1182/blood.V128.22.716.716

Published: 2016

Journal Articles

Circulating Activated Protein C in Thrombophilia Carriers

Thijs E van Mens, MD MBA, Joost C.M. Meijers, PhD Professor, Saskia Middeldorp, MD PhD Professor of MDcine

Blood (2016) 128 (22): 4948.

https://doi.org/10.1182/blood.V128.22.4948.4948

Published: 2016

Journal Articles

Phase I Study of Dose-Adjusted-Teddi-R with Ibrutinib in Untreated and Relapsed/Refractory Primary CNS Lymphoma

Kieron Dunleavy, MD, Catherine E. Lai, MD, Mark Roschewski, MD, Jennifer N Brudno, MD, Brigitte Widemann, MD, Stefania Pittaluga, MD PhD, Elaine S Jaffe, MD, Andrea N Lucas, RN, Maryalice Stetler-Stevenson, MD PhD, Constance M. Yuan, MD PhD, Pamela Harris, MD, Diane Cole, John A Butman, MD, Richard F Little, MD, Louis M Staudt, MD, Wyndham H Wilson, MD PhD

Blood (2015) 126 (23): 472.

https://doi.org/10.1182/blood.V126.23.472.472

Published: 2015

Journal Articles

HDAC8 Overexpression in Mesenchymal Stromal Cells from JAK2 + myeloproliferative Neoplasms: A New Therapeutic Target?

Teresa L. Ramos, Luis Ignacio Sánchez-Abarca, Rosón Beatriz, Concepción Rodríguez Serrano, Alba Redondo, Rebeca Ortega, Ángel Hernández-Hernández, Sandra Muntión, Silvia Preciado, José Ramón González-Porras, MD, Fermín Sánchez-Guijo, MD, Consuelo Del CaÃ±izo, MD

Blood (2015) 126 (23): 2831.

https://doi.org/10.1182/blood.V126.23.2831.2831

Published: 2015

Journal Articles

HDAC8 Mediates Homologous Recombination and Cytoskeleton Integrity in Myeloma with Potential Impact on Cell Growth and Survival

Maria Gkotzamanidou, MD PhD, Masood Shammas, PhD, Jesus Martin Sanchez, MD, Lai Ding, Stephane Minvielle, Florence Magrangeas, Herve Avet-Loiseau, Kenneth C. Anderson, MD, Nikhil C. Munshi, MD

Blood (2014) 124 (21): 416.

https://doi.org/10.1182/blood.V124.21.416.416

Published: 2014

NARROW

Identification of Novel Synthetic Lethal Partners of NAMPT Inhibitor By CRISPR-Cas9 Screens in Acute Myeloid Leukemia

Net Clinical Benefit of Low Dose Rivaroxaban in Coronary Heart Disease: A Systematic Review and Meta-Analysis

Safety and Antithrombotic Efficacy of the Recombinant Protein C Activator AB002 (E-WE Thrombin) in End Stage Renal Disease Patients on Chronic Hemodialysis

HDAC8 Maintain Cytoskeleton Integrity Via Homologous Recombination and Represent a Novel Therapeutic Target in Multiple Myeloma

A Quantitative Systems Pharmacology (QSP) Model to Predict Receptor Occupancy of Bruton's Tyrosine Kinase (BTK) Inhibitors in Peripheral Blood Mononuclear Cells, Bone Marrow and Lymph Nodes of Patients with B-Cell Malignancies

Design and characterization of α1-antitrypsin variants for treatment of contact system–driven thromboinflammation

A Direct Oral Anticoagulant Edoxaban Enhanced Fibrinolysis Via Inhibition of Thrombin-Activatable Fibrinolysis Inhibitor Activation and Enhancement of Plasmin Generation in Human Plasma

Rivaroxaban Thromboprophylaxis in High-Risk Ambulatory Cancer Patients Receiving Systemic Therapy: Results of a Randomized Clinical Trial (CASSINI)

Efficacy of Anti-TFPI Antibody PF-06741086 Alone and in Combination with Activated Prothrombin Complex Concentrates in Mouse Hemophilia a Bleeding Model

Restrictive Versus Liberal Red Blood Cell Transfusion for Cardiac Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Histone Deacetylase Inhibitors Downregulate CCR4 Expression and Decrease Mogamulizumab Efficacy in CCR4-Positive Mature T-Cell Lymphomas

Phenotype Does Not Always Equal Function: HDAC Inhibitors and UM171, but Not SR1, Lead to Rapid Upregulation of CD90 on Non-Engrafting CD34+CD90-Negative Human Cells

Design and characterization of an APC-specific serpin for the treatment of hemophilia

A Drug-Drug Interaction Study of Ibrutinib with Moderate and Strong CYP3A Inhibitors in Patients with B-Cell Malignancy

An Open-Label, Sequential-Design Drug Interaction Study of the Effects of Omeprazole on the Pharmacokinetics of Ibrutinib in Healthy Adults

Spatially Organized Structure of Coronary Thrombus in Acute Myocardial Infarction

Circulating Activated Protein C in Thrombophilia Carriers

Phase I Study of Dose-Adjusted-Teddi-R with Ibrutinib in Untreated and Relapsed/Refractory Primary CNS Lymphoma

HDAC8 Overexpression in Mesenchymal Stromal Cells from JAK2 + myeloproliferative Neoplasms: A New Therapeutic Target?

HDAC8 Mediates Homologous Recombination and Cytoskeleton Integrity in Myeloma with Potential Impact on Cell Growth and Survival

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American Society of Hematology

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American Society of Hematology

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