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Journal Articles

Genetic Activation of NRF2 By KEAP1 Inhibition Induces Fetal Hemoglobin Expression and Triggers Anti-Oxidant Stress Response in Erythroid Cells

Dipti Gupta, Samuel Lessard, PhD, Nancy Moore, Jicheng Duan, PhD, Yukio Nakamura, MD PhD, Feng-Chun Yang, MD PhD, Alexandra Hicks, PhD, David R. Light, PhD, Sriram Krishnamoorthy, PhD

Blood (2019) 134 (Supplement_1): 210.

https://doi.org/10.1182/blood-2019-129479

Published: 2019

Journal Articles

Warfarin alters vitamin K metabolism: a surprising mechanism of VKORC1 uncoupling necessitates an additional reductase

Mark A. Rishavy, Kevin W. Hallgren, Lee Wilson, Savita Singh, Kurt W. Runge, Kathleen L. Berkner

Blood (2018) 131 (25): 2826–2835.

https://doi.org/10.1182/blood-2017-09-804666

Published: 2018

Includes: Supplemental data

Journal Articles

Loss of NRF2 Function Worsens the Pathophysiology of Sickle Cell Disease in a Transgenic Mouse Model

Xingguo Zhu, PhD, Betty S. Pace, MD

Blood (2017) 130 (Supplement 1): 960.

https://doi.org/10.1182/blood.V130.Suppl_1.960.960

Published: 2017

Journal Articles

VKORc1 Is Under-Expressed in Skeletal Muscle of Humans, Dogs and Mice: Potential Implications for Ectopic Coagulation Factor Expression in Pre-Clinical and Therapeutic Applications

Courtney T Connolly, Armida Faella, Timothy C. Nichols, MD, Katherine A. High, MD, Valder R. Arruda, MD, PhD, Paris Margaritis, DPhil

Blood (2014) 124 (21): 1477.

https://doi.org/10.1182/blood.V124.21.1477.1477

Published: 2014

Journal Articles

Functional Polymorphisms in Oxidant Metabolism and DNA Repair Pathways and Risk of Leukemia and Transient Myeloproliferative Disorder in Children with Down Syndrome

Melissa S Rayburg, MD, Mi-Ok Kim, Todd Alonzo, PhD, Robert Gerbing, Gretchen A Radloff, Stella M Davies, Alan Gamis, MD, John Perentesis

Blood (2008) 112 (11): 2947.

https://doi.org/10.1182/blood.V112.11.2947.2947

Published: 2008

Journal Articles

Molecular Phenotype of Sickle Chronic Lung Disease Revealed by Global Gene Expression Profiling

Fang Tan, Tianwei Yu, Yuhua Li, Samit Ghosh, Mario Mosunjac, Solomon F Ofori-Acquah

Blood (2008) 112 (11): 2480.

https://doi.org/10.1182/blood.V112.11.2480.2480

Published: 2008

Journal Articles

High Risk of Acute Myeloid Leukemia in Individuals with NAD(P)H:Quinone Oxidoreductase 1 ( NQO1 ) and Cytochrome P450 A1 ( CYP1A1 ) Gene Defects.

Gabriela G. Yamaguti, Gustavo J. Lourenco, M.Sc., Fernando F. Costa, Ph.D., Carmen S.P. Lima, Ph.D.

Blood (2007) 110 (11): 2843.

https://doi.org/10.1182/blood.V110.11.2843.2843

Published: 2007

Journal Articles

The NAD(P)H:Quinone Oxidoreductase (NQO1) C609T Polymorphism Is Found at Variable Frequency in Different Ethnic Groups but Does Not Predispose to De Novo AML in Israel.

Elad Malik, BSc Med, Sara B. Cohen, PhD, Deborah Rund, MD

Blood (2004) 104 (11): 4381.

https://doi.org/10.1182/blood.V104.11.4381.4381

Published: 2004

Journal Articles

Low NAD(P)H:quinone oxidoreductase activity is associated with increased risk of leukemia with MLL translocations in infants and children

Martyn T. Smith, Yunxia Wang, Christine F. Skibola, Diana J. Slater, Luca Lo Nigro, Peter C. Nowell, Beverly J. Lange, Carolyn A. Felix

Blood (2002) 100 (13): 4590–4593.

https://doi.org/10.1182/blood-2001-12-0264

Published: 2002

Journal Articles

Low NAD(P)H:quinone oxidoreductase 1 activity is associated with increased risk of acute leukemia in adults

Martyn T. Smith, Yunxia Wang, Eleanor Kane, Sara Rollinson, Joseph L. Wiemels, Eve Roman, Philippa Roddam, Raymond Cartwright, Gareth Morgan

Blood (2001) 97 (5): 1422–1426.

https://doi.org/10.1182/blood.V97.5.1422

Published: 2001

Journal Articles

Prevalence of the Inactivating 609 C→T Polymorphism in the NAD(P)H:Quinone Oxidoreductase (NQO1) Gene in Patients With Primary and Therapy-Related Myeloid Leukemia

Richard A. Larson, Yunxia Wang, Mekhala Banerjee, Joseph Wiemels, Christine Hartford, Michelle M. Le Beau, Martyn T. Smith

Blood (1999) 94 (2): 803–807.

https://doi.org/10.1182/blood.V94.2.803

Published: 1999

NARROW

Genetic Activation of NRF2 By KEAP1 Inhibition Induces Fetal Hemoglobin Expression and Triggers Anti-Oxidant Stress Response in Erythroid Cells

Warfarin alters vitamin K metabolism: a surprising mechanism of VKORC1 uncoupling necessitates an additional reductase

Loss of NRF2 Function Worsens the Pathophysiology of Sickle Cell Disease in a Transgenic Mouse Model

VKORc1 Is Under-Expressed in Skeletal Muscle of Humans, Dogs and Mice: Potential Implications for Ectopic Coagulation Factor Expression in Pre-Clinical and Therapeutic Applications

Functional Polymorphisms in Oxidant Metabolism and DNA Repair Pathways and Risk of Leukemia and Transient Myeloproliferative Disorder in Children with Down Syndrome

Molecular Phenotype of Sickle Chronic Lung Disease Revealed by Global Gene Expression Profiling

High Risk of Acute Myeloid Leukemia in Individuals with NAD(P)H:Quinone Oxidoreductase 1 ( NQO1 ) and Cytochrome P450 A1 ( CYP1A1 ) Gene Defects.

The NAD(P)H:Quinone Oxidoreductase (NQO1) C609T Polymorphism Is Found at Variable Frequency in Different Ethnic Groups but Does Not Predispose to De Novo AML in Israel.

Low NAD(P)H:quinone oxidoreductase activity is associated with increased risk of leukemia with MLL translocations in infants and children

Low NAD(P)H:quinone oxidoreductase 1 activity is associated with increased risk of acute leukemia in adults

Prevalence of the Inactivating 609 C→T Polymorphism in the NAD(P)H:Quinone Oxidoreductase (NQO1) Gene in Patients With Primary and Therapy-Related Myeloid Leukemia

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