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Journal Articles

Myeloid cell–targeted miR-146a mimic inhibits NF-κB–driven inflammation and leukemia progression in vivo

Yu-Lin Su, Xiuli Wang, Mati Mann, Tomasz P. Adamus, Dongfang Wang, Dayson F. Moreira, Zhuoran Zhang, Ching Ouyang, Xin He, Bin Zhang, Piotr M. Swiderski, Stephen J. Forman, David Baltimore, Ling Li, Guido Marcucci, Mark P. Boldin, Marcin Kortylewski

Blood (2020) 135 (3): 167–180.

https://doi.org/10.1182/blood.2019002045

Published: 2020

Includes: Supplemental data

Journal Articles

Signaling Pathways of Mutant IDH1 Independent of R-2-Hydroxyglutarate

Charu Gupta, Michelle Maria Araujo Cruz, PhD, Nidhi Jyotsana, PhD, Amit Sharma, PhD, Ramya Goparaju, PhD, Kerstin Görlich, Renate Schottmann, Eduard Struys, PhD, Erwin E Jansen, Felicitas Thol, MD, Arnold Ganser, MD, Michael Heuser, MD, Anuhar Chaturvedi, PhD

Blood (2018) 132 (Supplement 1): 2617.

https://doi.org/10.1182/blood-2018-99-110159

Published: 2018

Journal Articles

Dependency of Spliceosomal Mutant MDS on Innate Immune Signaling

Stanley C Lee, PhD, Khrystyna North, Chi-Chao Chen, Eunhee Kim, PhD, Sydney X. Lu, MD PhD, Michelle Ki, BSc, Ralph Garippa, PhD, Scott W Lowe, PhD, Robert K. Bradley, PhD, Omar I Abdel-Wahab, MD

Blood (2018) 132 (Supplement 1): 937.

https://doi.org/10.1182/blood-2018-99-111552

Published: 2018

Journal Articles

Benefits and risks of JAK inhibition

Luca Arcaini, Mario Cazzola

Blood (2018) 132 (7): 675–676.

https://doi.org/10.1182/blood-2018-07-858720

Published: 2018

Journal Articles

Characterization and Targeting TET2-Mutant HSPCs and AML

Yusuke Nakauchi, MD PhD, Daniel Thomas, MD PhD, Andreas Reinisch, MD PhD, Rajiv Sharma, PhD, David Cruz, BS, M. Ryan Corces, PhD, Ravi Majeti, MD PhD

Blood (2017) 130 (Supplement 1): 2509.

https://doi.org/10.1182/blood.V130.Suppl_1.2509.2509

Published: 2017

Journal Articles

The Role of Kdm6a in Malignant Hematopoiesis

Ling Tian, PhD, Lukas D Wartman, MD

Blood (2017) 130 (Supplement 1): 1227.

https://doi.org/10.1182/blood.V130.Suppl_1.1227.1227

Published: 2017

Journal Articles

How Somatic Mutations Carve Morphologic Imprint in MDS?

Abhinav Goyal, MD, Mohammad Fahad B Asad, MD MBBS, Hassan Awada, MD, Mai Aly, MD, Cassandra M. Hirsch, BS, Bartlomiej P. Przychodzen, MSc, Tomas Radivoyevitch, PhD, Aziz Nazha, MD, Sudipto Mukherjee, MD PhD MPH, Mikkael A. Sekeres, MD MS, Jaroslaw P. Maciejewski, PhD MD FACP, Yasunobu Nagata, MD PhD

Blood (2017) 130 (Supplement 1): 2949.

https://doi.org/10.1182/blood.V130.Suppl_1.2949.2949

Published: 2017

Journal Articles

Chromatin Regulator Mutations Are Drivers of Clonal Evolution in the Early Multipotent HSC Compartment of Primary Myelofibrosis

Ioanna Triviai, Jan Rentel, Silke Zeschke, Carol Stocking, PhD, Kroger Nicolaus

Blood (2017) 130 (Supplement 1): 1658.

https://doi.org/10.1182/blood.V130.Suppl_1.1658.1658

Published: 2017

Journal Articles

NPM1 Mutation Contributes to Hematological Dysfunction By Disrupting H3K79 Methylation

Jie Xu, MD, PhD, Wu Zhang, PhD, Xiaojing Yan, MD PhD, Chen Zhao, Jiang Zhu, MD PhD, Zhu Chen, Sai-Juan Chen, MD, PhD, Jiong Hu, Sr., Doctor

Blood (2016) 128 (22): 2702.

https://doi.org/10.1182/blood.V128.22.2702.2702

Published: 2016

Journal Articles

Crispr/Cas9 Engineered 61bp Deletion in the Calr Gene of Mice Leads to Development of Thrombocytosis

Thomas Balligand, MD, Younes Achouri, PhD, Ilyas Chachoua, MSc, Christian Pecquet, PhD, Jean-Philippe Defour, BPharm,, Stefan N. Constantinescu

Blood (2016) 128 (22): 4274.

https://doi.org/10.1182/blood.V128.22.4274.4274

Published: 2016

Journal Articles

ASXL2 Is Recurrently Mutated in t(8;21) AML and Regulates Hematopoietic Development

Blood (2016) 128 (22): 1051.

https://doi.org/10.1182/blood.V128.22.1051.1051

Published: 2016

Journal Articles

High Spontaneous In Vitro Myeloid Colony Formation in Chronic Myelomonocytic Leukemia is Associated with Mutations in Rasopathy Genes, Myeloproliferation and Inferior Prognosis

Blood (2016) 128 (22): 5503.

https://doi.org/10.1182/blood.V128.22.5503.5503

Published: 2016

Journal Articles

Activation of JAK/STAT Signaling in Megakaryocytes Is Necessary and Sufficient for Myeloproliferation In Vivo

Q. Jeremy Wen, Brittany Woods, PhD, Qiong Yang, MD, Chiu Sophia, Gu Lillu, Franck Rapaport, PhD, Ross L. Levine, MD, John Crispino, PhD MBA

Blood (2016) 128 (22): 949.

https://doi.org/10.1182/blood.V128.22.949.949

Published: 2016

Journal Articles

Modeling Clonal Hematopoietic Disorders in Zebrafish Using Color Barcoding

Serine Avagyan, MD PhD, Jonathan E Henninger, Jessica Moore, William Mannherz, Leonard I. Zon, MD

Blood (2016) 128 (22): 3147.

https://doi.org/10.1182/blood.V128.22.3147.3147

Published: 2016

Journal Articles

Negative Feedback By Dusp6 Modulates Myeloproliferation Induced By Oncogenic Nras

Charisa Cottonham, PhD, Jon Akutagawa, Inbal Epstein, Lana Bogdanova, Benjamin S. Braun, MD PhD

Blood (2015) 126 (23): 1256.

https://doi.org/10.1182/blood.V126.23.1256.1256

Published: 2015

Journal Articles

Depletion of Ptch2 Activates Canonical and Non-Canonical HH Signaling within the Niche Leading to Myeloproliferation, Stem Cell Exhaustion and Accelerates JAK2V617F Driven Disease

Claudius Klein, Anabel Kuhn, Sandra Kissel, Marie Follo, PhD, Anna Lena Illert, MD, Dietmar Pfeifer, Heike L Pahl, PhD, Robert A.J. Oostendorp, PhD, Justus Duyster, MD, Christine Dierks, MD

Blood (2015) 126 (23): 3593.

https://doi.org/10.1182/blood.V126.23.3593.3593

Published: 2015

Journal Articles

Reacting to Inflammatory Signals

Nadia Carlesso, MD PhD

Blood (2015) 126 (23): SCI-30.

https://doi.org/10.1182/blood.V126.23.SCI-30.SCI-30

Published: 2015

Journal Articles

Loss of MiR-143 and MiR-145 Inhibits Hematopoietic Stem Cell Self-Renewal through Dysregulated TGFβ Signaling

Jeffrey C Lam, BSc, Joanna Wegrzyn-Woltosz, PhD, Rawa Ibrahim, BSc, Kate Slowski, BSc, Patricia Umlandt, BSc, Megan Fuller, BSc, Aly Karsan, MD

Blood (2014) 124 (21): 527.

https://doi.org/10.1182/blood.V124.21.527.527

Published: 2014

Journal Articles

Conditional Loss of Dnmt3a Results in Myeloproliferation and Liver-Specific Myeloid Expansion

Olga A Guryanova, MD PhD, Yen Lieu, PhD, Kaitlyn R Shank, B.S., Sharon Rivera, PhD, Francine E Garrett-Bakelman, MD PhD, Jacob Glass, MD PhD, Matthew D Keller, B.S., Suveg Pandey, B.S., Daniel Tovbin, Abby R Weinstein, Julie Teruya-Feldstein, MD, Omar Abdel-Wahab, MD, Christopher E Mason, PhD, Ari M Melnick, MD, Siddhartha Mukherjee, MD PhD, Ross L. Levine, MD

Blood (2014) 124 (21): 364.

https://doi.org/10.1182/blood.V124.21.364.364

Published: 2014

Journal Articles

Comprehensive Genetic Analyses Of 213 PMF Patients Revealed 13% Of SRSF2 Mutations Being Strongly Correlated To ASXL1 Mutations

Manja Meggendorfer, PhD, Tamara Alpermann, Christiane Eder, PhD, Claudia Haferlach, MD, Wolfgang Kern, MD, Torsten Haferlach, MD, Susanne Schnittger, PhD

Blood (2013) 122 (21): 2828.

https://doi.org/10.1182/blood.V122.21.2828.2828

Published: 2013

NARROW

Myeloid cell–targeted miR-146a mimic inhibits NF-κB–driven inflammation and leukemia progression in vivo

Signaling Pathways of Mutant IDH1 Independent of R-2-Hydroxyglutarate

Dependency of Spliceosomal Mutant MDS on Innate Immune Signaling

Benefits and risks of JAK inhibition

Characterization and Targeting TET2-Mutant HSPCs and AML

The Role of Kdm6a in Malignant Hematopoiesis

How Somatic Mutations Carve Morphologic Imprint in MDS?

Chromatin Regulator Mutations Are Drivers of Clonal Evolution in the Early Multipotent HSC Compartment of Primary Myelofibrosis

NPM1 Mutation Contributes to Hematological Dysfunction By Disrupting H3K79 Methylation

Crispr/Cas9 Engineered 61bp Deletion in the Calr Gene of Mice Leads to Development of Thrombocytosis

ASXL2 Is Recurrently Mutated in t(8;21) AML and Regulates Hematopoietic Development

High Spontaneous In Vitro Myeloid Colony Formation in Chronic Myelomonocytic Leukemia is Associated with Mutations in Rasopathy Genes, Myeloproliferation and Inferior Prognosis

Activation of JAK/STAT Signaling in Megakaryocytes Is Necessary and Sufficient for Myeloproliferation In Vivo

Modeling Clonal Hematopoietic Disorders in Zebrafish Using Color Barcoding

Negative Feedback By Dusp6 Modulates Myeloproliferation Induced By Oncogenic Nras

Depletion of Ptch2 Activates Canonical and Non-Canonical HH Signaling within the Niche Leading to Myeloproliferation, Stem Cell Exhaustion and Accelerates JAK2V617F Driven Disease

Reacting to Inflammatory Signals

Loss of MiR-143 and MiR-145 Inhibits Hematopoietic Stem Cell Self-Renewal through Dysregulated TGFβ Signaling

Conditional Loss of Dnmt3a Results in Myeloproliferation and Liver-Specific Myeloid Expansion

Comprehensive Genetic Analyses Of 213 PMF Patients Revealed 13% Of SRSF2 Mutations Being Strongly Correlated To ASXL1 Mutations

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American Society of Hematology

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ASH Publications

American Society of Hematology

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