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Journal Articles

Exploitation of a Newly Characterized Metabolic-Cytoskeletal Axis for Effective Combination Therapy of Iron Restricted Anemia

Adam N Goldfarb, MD, Katie Freeman, BA, Alejandro Ariel Gru, MD, Zollie White, III, MS, Lorrie L Delehanty, BS

Blood (2019) 134 (Supplement_1): 2233.

https://doi.org/10.1182/blood-2019-129172

Published: 2019

Journal Articles

Autophagy and Ubiquitin-Mediated Proteolytic Degradation of PML/RarÎ± Fusion Protein in Matrine-Induced Differentiation Sensitivity Recovery of ATRA-Resistant APL (NB4-LR1) Cells: In Vitro and In Vivo studies

Dijiong Wu, Keding Shao, MD, Qihao Zhou, MD, Jie Sun, Ziqi Wang, Fei Yan, Tingting Liu, Xiangping Wu, Baodong Ye, He Huang, MD PhD, Yuhong Zhou

Blood (2018) 132 (Supplement 1): 2646.

https://doi.org/10.1182/blood-2018-99-115699

Published: 2018

Journal Articles

Chromatin Accessibility Profiling Reveals Cis-Regulatory Heterogeneity and Novel Transcription Factor Dependencies in Multiple Myeloma

Christopher J. Ott, PhD, Raphael Szalat, MD, Matthew Lawlor, Mehmet Kemal Samur, PhD, Yan Xu, MD, Charles B Epstein, Charles Y Lin, PhD, Rao Prabhala, PhD, Nina Farrell, Lauren D Walter, Logan Schwartz, Kenneth Wen, BS, Yu-Tzu Tai, PhD, Mariateresa Fulciniti, PhD, Jinhua Wang, PhD, Nathanael Gray, PhD, Kenneth Anderson, MD, Richard A. Young, PhD, Nikhil Munshi, MD

Blood (2018) 132 (Supplement 1): 1313.

https://doi.org/10.1182/blood-2018-99-119941

Published: 2018

Journal Articles

Activation of Autophagy in Models of SF3B1 Mutant MDS

Blood (2017) 130 (Supplement 1): 4230.

https://doi.org/10.1182/blood.V130.Suppl_1.4230.4230

Published: 2017

Journal Articles

Synergistic Activity of Lysine Deacetylase Inhibitors and Microtubule-Targeting Agents in AML

James M Bogenberger, PhD, Nanna Hansen, M.S., Devora Delman, B.S., Lisa Sproat, MD MSW, Jeanne Palmer, MD, Ruben Mesa, MD FACP, Raoul Tibes, MD PhD

Blood (2016) 128 (22): 3948.

https://doi.org/10.1182/blood.V128.22.3948.3948

Published: 2016

Journal Articles

Evaluation of Patient-Derived Xenografts for Modeling Outcome of Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia

Abdulmohsen M Alruwetei, Msc, Hernan Carol, PhD, Rosemary Sutton, PhD, Glenn M Marshall, MBBS, MD FRACP, Richard B Lock, PhD

Blood (2015) 126 (23): 3759.

https://doi.org/10.1182/blood.V126.23.3759.3759

Published: 2015

Journal Articles

Autophagy Is an Important Event for Low Dose Cytarabine Treatment in Acute Myeloid Leukemia U937 Cell Line

Liyun Chen, Pei Guo, Peimin Jia, Jianhua Tong, Jiong Hu, Junmin Li, MD PhD

Blood (2014) 124 (21): 5209.

https://doi.org/10.1182/blood.V124.21.5209.5209

Published: 2014

Journal Articles

Autophagy Inhibition Overcomes Resistance to Cytosine Arabinoside in Acute Myeloid Leukemia Cells through Inducing Autophagic Cell Death and Intrinsic Pathway Apoptosis

Yundeok Kim, MD, Ju-In Eom, Hoi-Kyung Jeung, Jieun Jang, MD, Jin Seok Kim, June-Won Cheong, MD,PhD, Young Sam Kim, Yoo Hong Min, MD,PhD

Blood (2014) 124 (21): 909.

https://doi.org/10.1182/blood.V124.21.909.909

Published: 2014

Journal Articles

Linking Organelle Remodeling with the Erythroid Cell Genetic Network

Yoon-A Kang, Jonathan N Ouellette, Genís Campreciós, PhD, Saghi Ghaffari, MD, PhD, Emery H Bresnick, PhD

Blood (2012) 120 (21): 367.

https://doi.org/10.1182/blood.V120.21.367.367

Published: 2012

Journal Articles

Inhibition of the HDM-2 E3 Ligase Induces Types I and II Cell Death in Wild-Type and Mutant p53 Models of Multiple Myeloma, and Acts Synergistically in Both with ABT-737.

Dongmin Gu, Ph.D., Richard Julian Jones, Ph.D., Hua Wang, Ph.D., Lance Leopold, M.D., Robert Z. Orlowski, M.D., Ph.D.

Blood (2012) 120 (21): 2940.

https://doi.org/10.1182/blood.V120.21.2940.2940

Published: 2012

Journal Articles

Macrolide Antibiotics Block Autophagy Flux and Sensitize to Bortezomib Via Endoplasmic Reticulum-Stress-Mediated CHOP Induction in Myeloma Cells

Shota Moriya, Xiao-Fang Che, MD, PhD, Seiichiro Komatsu, MD, Akihisa Abe, PhD, Tomohiro Kawaguchi, Akihiko Gotoh, MD, PhD, Masato Inazu, PhD, Akio Tomoda, MD, PhD, Keisuke Miyazawa, MD, PhD

Blood (2012) 120 (21): 4992.

https://doi.org/10.1182/blood.V120.21.4992.4992

Published: 2012

Journal Articles

FTY720 Induces Apoptosis and Autophagy in Multiple Myeloma Cells

Aijun Liao, Rong Hu, Qihui Zhao, Huihan Wang, Yingchun Li, Kun Yao, Rong Zhang, Wei Yang, Zhuogang Liu

Blood (2011) 118 (21): 5103.

https://doi.org/10.1182/blood.V118.21.5103.5103

Published: 2011

Journal Articles

MicroRNA-130a Targets ATG2B , AGO4 and DICER1 , Inhibits Autophagy and Induces Cell Death in Chronic Lymphocytic Leukemia

Valentina Kovaleva, Rodrigo Mora, PhD, Stephan Stilgenbauer, MD, Peter Lichter, Martina Seiffert, PhD

Blood (2011) 118 (21): 1768.

https://doi.org/10.1182/blood.V118.21.1768.1768

Published: 2011

Journal Articles

Indirubin-3'-Monoxime Induces Apoptosis and Autophagy In Acute Lymphoblastic Leukemia Cells and Chronic Myelogenous Leukemia Cells, Exhibits Limited Cytotoxicity In CD34 + Hematopoietic Stem Cells, Lymphocytes and Granulocytes

Ming-Yang Lee, Yi-Wen Liu, Ming-Ho Chen, Jing-Jing Chuang

Blood (2010) 116 (21): 3984.

https://doi.org/10.1182/blood.V116.21.3984.3984

Published: 2010

Journal Articles

Mature Erythroblasts Die of Autophagy and Induce Autophagy of Immature Erythroblasts, Limiting the Final Cellular Output In Human Erythroid Massive Amplification (HEMA) Culture

Giovanni Migliaccio, PhD, Francesca Masiello, Valentina Tirelli, Massimo Sanchez, Lilian Varricchio, Carolyn Whitsett, Anna Rita F Migliaccio, PhD

Blood (2010) 116 (21): 339.

https://doi.org/10.1182/blood.V116.21.339.339

Published: 2010

Journal Articles

Inhibition of the Human Double Minute (HDM)-2 E3 Ubiquitin Ligase Activates Different Programmed Cell Death (PCD) Pathways in Models of Non-Hodgkin Lymphoma (NHL) with Wild Type (wt) and Mutant (mut) p53

Richard Julian Jones, PhD, Janine Arts, PhD, Robert Z Orlowski, MD, PhD

Blood (2008) 112 (11): 3618.

https://doi.org/10.1182/blood.V112.11.3618.3618

Published: 2008

Journal Articles

Autophagy Induction of Acute Myeloid Leukemia (AML) Cells after Treatment with Low Dose-Cytarabine (Ara-C) and Enhanced Cytocidal Effect on AML Cells by Combined Treatment with Ara-C Plus Lenograstim.

Keisuke Miyazawa, MD, Juri Toyotake, MD, Munekazu Naito, MD, Masahiro Itoh, MD, Kazuma Ohyashiki, MD

Blood (2007) 110 (11): 4185.

https://doi.org/10.1182/blood.V110.11.4185.4185

Published: 2007

Journal Articles

Kinesin Family Member 20A (KIF20A) Is Specifically down Regulated in 5q- CD34+ and CD61+ Cells and Uniparental Disomy Is Not a Feature of 5q- Syndrome.

Nicholas C. Lea, PhD, Azim Mohamedali, PhD, Natalie Twine, MSc, Joop Gaken, Phd, Nigel Westwood, Phd, Wendy Ingram, MBBS, Ghulam Mufti, MD

Blood (2006) 108 (11): 2611.

https://doi.org/10.1182/blood.V108.11.2611.2611

Published: 2006

Journal Articles

Targeting the p27 Kip1 E3 Ubiquitin Ligase for the Treatment of Multiple Myeloma and Other Hematological Malignancies.

Qing Chen, PhD, Weilin Xie, PhD, Deborah J. Kuhn, PhD, Peter M. Voorhees, MD, Derek Mendy, MD, Antonia Lopez-Girona, PhD, Veronique Plantevin, PhD, Weiming Xu, PhD, Laura De Parseval, PhD, Laura G. Corral, PhD, Emilia Glezer, PhD, Kyle Chan, PhD, Frank Mercurio, PhD, Robert Z. Orlowski, MD, PhD

Blood (2006) 108 (11): 372.

https://doi.org/10.1182/blood.V108.11.372.372

Published: 2006

Journal Articles

Umbilical Cord Blood Cells Express mRNA for Neuronal Genes MAP2 and NEFL.

Martin Korbling, MD, Wei Zhang, PhD, David Cogdell, PhD, James Reuben, MD, Hui Gao, PhD, Dongxia Xing, PhD, Ruth Katz, MD, Kawah Chan, MD, Elizabeth Shpall, MD

Blood (2006) 108 (11): 5154.

https://doi.org/10.1182/blood.V108.11.5154.5154

Published: 2006

NARROW

Exploitation of a Newly Characterized Metabolic-Cytoskeletal Axis for Effective Combination Therapy of Iron Restricted Anemia

Autophagy and Ubiquitin-Mediated Proteolytic Degradation of PML/RarÎ± Fusion Protein in Matrine-Induced Differentiation Sensitivity Recovery of ATRA-Resistant APL (NB4-LR1) Cells: In Vitro and In Vivo studies

Chromatin Accessibility Profiling Reveals Cis-Regulatory Heterogeneity and Novel Transcription Factor Dependencies in Multiple Myeloma

Activation of Autophagy in Models of SF3B1 Mutant MDS

Synergistic Activity of Lysine Deacetylase Inhibitors and Microtubule-Targeting Agents in AML

Evaluation of Patient-Derived Xenografts for Modeling Outcome of Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia

Autophagy Is an Important Event for Low Dose Cytarabine Treatment in Acute Myeloid Leukemia U937 Cell Line

Autophagy Inhibition Overcomes Resistance to Cytosine Arabinoside in Acute Myeloid Leukemia Cells through Inducing Autophagic Cell Death and Intrinsic Pathway Apoptosis

Linking Organelle Remodeling with the Erythroid Cell Genetic Network

Inhibition of the HDM-2 E3 Ligase Induces Types I and II Cell Death in Wild-Type and Mutant p53 Models of Multiple Myeloma, and Acts Synergistically in Both with ABT-737.

Macrolide Antibiotics Block Autophagy Flux and Sensitize to Bortezomib Via Endoplasmic Reticulum-Stress-Mediated CHOP Induction in Myeloma Cells

FTY720 Induces Apoptosis and Autophagy in Multiple Myeloma Cells

MicroRNA-130a Targets ATG2B , AGO4 and DICER1 , Inhibits Autophagy and Induces Cell Death in Chronic Lymphocytic Leukemia

Indirubin-3'-Monoxime Induces Apoptosis and Autophagy In Acute Lymphoblastic Leukemia Cells and Chronic Myelogenous Leukemia Cells, Exhibits Limited Cytotoxicity In CD34 + Hematopoietic Stem Cells, Lymphocytes and Granulocytes

Mature Erythroblasts Die of Autophagy and Induce Autophagy of Immature Erythroblasts, Limiting the Final Cellular Output In Human Erythroid Massive Amplification (HEMA) Culture

Inhibition of the Human Double Minute (HDM)-2 E3 Ubiquitin Ligase Activates Different Programmed Cell Death (PCD) Pathways in Models of Non-Hodgkin Lymphoma (NHL) with Wild Type (wt) and Mutant (mut) p53

Autophagy Induction of Acute Myeloid Leukemia (AML) Cells after Treatment with Low Dose-Cytarabine (Ara-C) and Enhanced Cytocidal Effect on AML Cells by Combined Treatment with Ara-C Plus Lenograstim.

Kinesin Family Member 20A (KIF20A) Is Specifically down Regulated in 5q- CD34+ and CD61+ Cells and Uniparental Disomy Is Not a Feature of 5q- Syndrome.

Targeting the p27 Kip1 E3 Ubiquitin Ligase for the Treatment of Multiple Myeloma and Other Hematological Malignancies.

Umbilical Cord Blood Cells Express mRNA for Neuronal Genes MAP2 and NEFL.

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American Society of Hematology

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American Society of Hematology

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