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Journal Articles

Modulation of Mesodermal Patterning Combined with High VEGFA Concentrations Promote Robust Arterial Hemogenic Endothelium Differentiation from Human iPSCs

Juan Pablo Ruiz, BS, Andre Larochelle, MD PhD

Blood (2018) 132 (Supplement 1): 5093.

https://doi.org/10.1182/blood-2018-99-119332

Published: 2018

Journal Articles

Mesenchymal Niche Cells Contributes to the Protection of Hematopoietic Stem Cells in Acute Lymphoblastic Leukemia

Chen Tian, M. James You, MD PhD, Zhang Yizhuo

Blood (2017) 130 (Supplement 1): 4815.

https://doi.org/10.1182/blood.V130.Suppl_1.4815.4815

Published: 2017

Journal Articles

Alteration of the Hematopoietic Components, Mesenchymal Stromal Cells and Vascular Elements in the Bone Marrow Niche in Myelodysplastic Syndrome: Refractory Cytopenia with Multilineage Dysplasia

Salar Abbas, M.Sc, Aparna Venkatraman, PhD, Sanjay Kumar, PhD, Archana Kini, M.Sc, Marie Therese Manipadam, MD, Vivi M Srivastava, MD, Eunice Sindhuvi, PhD, Vikram Mathews, MD DM, Biju George, MD DM, Alok Srivastava

Blood (2016) 128 (22): 5516.

https://doi.org/10.1182/blood.V128.22.5516.5516

Published: 2016

Journal Articles

Activation of Notch-Hes Signaling Pathway Impairs Osteogenic Differentiation and Hematopoietic Stem Cell-Supporting Capacitiy of Mesenchymal Stromal Cells Derived from Myelodysplastic Syndromes Patients

Chunkang Chang, MDPhD, Chengming Fei, MD, Juan Guo, MD, Youshan Zhao, MD, Shucheng Gu, MD, Xiao Li, MD PhD

Blood (2015) 126 (23): 2857.

https://doi.org/10.1182/blood.V126.23.2857.2857

Published: 2015

Journal Articles

Stimulatory Effects of Serum for Ex-Vivo Culture of Mesenchymal Stromal Cells Can be a Parameter for Heterogeneity in Hematopoietic Supporting Activity

Jung-Ho Kim, Ho-Sun Lee, In-Sun Chu, Il-Hoan Oh, MD PhD

Blood (2015) 126 (23): 5407.

https://doi.org/10.1182/blood.V126.23.5407.5407

Published: 2015

Journal Articles

5-Fluorouracil Treatment Leads to Activation of Stem Cell Niche By Reconstructing Mesenchymal Stromal Cells and Exert a Distinct Microenvironmental Impact on Normal and Leukemic Cells

Seon-Yeong Jeong, Jin-A Kim, Il-Hoan Oh, MD PhD

Blood (2015) 126 (23): 1197.

https://doi.org/10.1182/blood.V126.23.1197.1197

Published: 2015

Journal Articles

Targeting the Osteoblast in Myelodysplasia and Acute Myeloid Leukemia

Masahiro Marshall Nakagawa, Aruna Kode, Sanil J Manavalan, Govind Bhagat, MD, Julie Teruya-Feldstein, MD, Azra Raza, MD, Ellin Berman, MD, Stavroula Kousteni

Blood (2015) 126 (23): 2551.

https://doi.org/10.1182/blood.V126.23.2551.2551

Published: 2015

Journal Articles

Osteoblast ablation reduces normal long-term hematopoietic stem cell self-renewal but accelerates leukemia development

Marisa Bowers, Bin Zhang, Yinwei Ho, Puneet Agarwal, Ching-Cheng Chen, Ravi Bhatia

Blood (2015) 125 (17): 2678–2688.

https://doi.org/10.1182/blood-2014-06-582924

Published: 2015

Includes: Supplemental data

Journal Articles

IL-17A-Mediated Notch Signaling in Multiple Myeloma

Rao H. Prabhala, PhD, Teru Hideshima, MD PhD, Mariateresa Fulciniti, PhD, Sophia Adamia, PhD, Rajya Lakshmi Bandi, BS, Puru Nanjappa, MS, Kenneth C. Anderson, Nikhil C. Munshi, MD

Blood (2014) 124 (21): 3434.

https://doi.org/10.1182/blood.V124.21.3434.3434

Published: 2014

Journal Articles

Foxo1 Expressed in Osteoblasts Promotes the Leukemogenic Properties of β-Catenin By Activating Notch Signaling

Aruna Kode, Ioanna Mosialou, Sanil J Manavalan, Julie Teruya Feldstein, Govind Bhagat, MD, Ellin Berman, MD, Stavroula Kousteni

Blood (2014) 124 (21): 2356.

https://doi.org/10.1182/blood.V124.21.2356.2356

Published: 2014

Journal Articles

Role of Stromal Cell-Mediated Notch Signaling in AML Resistance to Chemotherapy

Paul Takam Kamga, Bassi Giulio, Adriana Cassaro, Roberta Stradoni, Martina Midolo, Omar Perbellini, MD, Mauro Krampera, MD PhD

Blood (2014) 124 (21): 1044.

https://doi.org/10.1182/blood.V124.21.1044.1044

Published: 2014

Journal Articles

Genomic Analisys of Notch Mutations in a Case of Alagille Syndrome with Acute Lymphoblastic Leukemia

Simona Bernardi, Paola Tononi, Sergio Marin Vargas, Giulio Bassi, MSc,PhD, Paul Takam Kamga, Omar Perbellini, MD, Achille Ambrosetti, Vittorio Meneghini, Luigi Scaffidi, Giovanni Martinelli, MD, Ilaria Iacobucci, PhD, Giovanni Pizzolo, MD, Massimo Delledonne, PhD, Mauro Krampera, MD PhD

Blood (2014) 124 (21): 5338.

https://doi.org/10.1182/blood.V124.21.5338.5338

Published: 2014

Journal Articles

Role Of Stromal Cell-Mediated Notch Signaling In Hematological Malignancies

Giulio Bassi, Paul Takam Kamga, Armel Nwabo Kamdje, Roberta Stradoni, Giorgio Malpeli, Eliana Amati, Ilaria Nichele, Roberta Carusone, Jasmina Zanoncello, Giovanni Pizzolo, MD, Mauro Krampera, MD, PhD

Blood (2013) 122 (21): 4939.

https://doi.org/10.1182/blood.V122.21.4939.4939

Published: 2013

Journal Articles

Diverse Impact of Notch-1, Jagged-1 and Dll-1 Expression On Response to Treatment and Relapse Free Survival in Acute Myeloid Leukemia.

Magdalena Czemerska, MD, Agnieszka Pluta, MD, PhD, Anna Szmigielska-Kaplon, MD, PhD, Ewa Wawrzyniak, PhD, Barbara Cebula-Obrzut, PhD, Aleksandra Medra, Piotr Smolewski, MD, PhD, Tadeusz Robak, MD, PhD, Agnieszka Wierzbowska, MD, PhD

Blood (2012) 120 (21): 2520.

https://doi.org/10.1182/blood.V120.21.2520.2520

Published: 2012

Journal Articles

Intermittent in Vivo Parathyroid Hormone (PTH) Treatment Results in Jagged 1 (Jag 1) Dependent and Independent Effects On Hematopoietic Stem Cells (HSCs)

Benjamin J Frisch, Ph.D., Ismat Shafiq, M.D., Rebecca L Porter, Ph.D., Jonathan M Weber, Ph.D., MBA, Julianne N Smith, M.S., Olga Bromberg, Miles Basil, Robinder S Dhillon, M.D., Edward M Schwarz, Ph.D., Laura M Calvi, M.D.

Blood (2012) 120 (21): 642.

https://doi.org/10.1182/blood.V120.21.642.642

Published: 2012

Journal Articles

Bone Marrow Niche Attenuation by Non-Steroidal Anti-Inflammatory Drugs Mobilizes Hematopoietic Stem and Progenitor Cells by Differing Mechanisms

Jonathan Hoggatt, Ph.D., Khalid S Mohammad, M.D. Ph.D., Brahmananda Reddy Chitteti, PhD, Pratibha Singh, PhD, Jennifer M Speth, Peirong Hu, PhD, Bradley Poteat, Edward Srour, PhD, Theresa Guise, M.D., Louis M. Pelus, PhD

Blood (2011) 118 (21): 724.

https://doi.org/10.1182/blood.V118.21.724.724

Published: 2011

Journal Articles

Vascular Pericytes Sustain Hematopoietic Stem Cells

Mirko Corselli, Chintan Parekh, Elisa Giovanna Angela Montelatici, Arineh Sahghian, Wenyuan Wang, Shundi Ge, Jessica Scholes, Felicia Codrea, Lorenza Lazzari, Gay M. Crooks, MBBS, Bruno Peault

Blood (2011) 118 (21): 2394.

https://doi.org/10.1182/blood.V118.21.2394.2394

Published: 2011

Journal Articles

The Complicated Network Structure and Activated Notch Signal Pathway in Embryo Heart of Mouse Provide the Favorable Microenvironment for HSCs Development and Proliferation During E10∼E12

Lifang Huang, Fankai Meng, Hanying Sun, Jianfeng Zhou, Yicheng Zhang, Wenli Liu

Blood (2011) 118 (21): 4806.

https://doi.org/10.1182/blood.V118.21.4806.4806

Published: 2011

Journal Articles

Notch Repression by LRF Is Necessary for the Maintenance of Adult Hematopoietic Stem Cell Pool.

Sung-UK Lee, PhD, Min Li, PhD, Manami Maeda, Nagisa Sakurai, Yuichi Ishikawa, MD, PhD, Freddy Radtke, Minhong Yan, Hugh Robson Macdonald, Takahiro Maeda, MD, PhD

Blood (2010) 116 (21): 2633.

https://doi.org/10.1182/blood.V116.21.2633.2633

Published: 2010

Journal Articles

Impaired Osteogenic Differentiation of Mesenchymal Stem Cells Derived From Multiple Myeloma Patients Is Associated with a Failure In the Deactivation of the NOTCH Pathway

Song Xu, Jinsong Hu, Dehui Xu, Isabelle Vande Broek, Xavier Leleu, Ben Van Camp, Karin Vanderkerken, Ivan Van Riet

Blood (2010) 116 (21): 1894.

https://doi.org/10.1182/blood.V116.21.1894.1894

Published: 2010

NARROW

Modulation of Mesodermal Patterning Combined with High VEGFA Concentrations Promote Robust Arterial Hemogenic Endothelium Differentiation from Human iPSCs

Mesenchymal Niche Cells Contributes to the Protection of Hematopoietic Stem Cells in Acute Lymphoblastic Leukemia

Alteration of the Hematopoietic Components, Mesenchymal Stromal Cells and Vascular Elements in the Bone Marrow Niche in Myelodysplastic Syndrome: Refractory Cytopenia with Multilineage Dysplasia

Activation of Notch-Hes Signaling Pathway Impairs Osteogenic Differentiation and Hematopoietic Stem Cell-Supporting Capacitiy of Mesenchymal Stromal Cells Derived from Myelodysplastic Syndromes Patients

Stimulatory Effects of Serum for Ex-Vivo Culture of Mesenchymal Stromal Cells Can be a Parameter for Heterogeneity in Hematopoietic Supporting Activity

5-Fluorouracil Treatment Leads to Activation of Stem Cell Niche By Reconstructing Mesenchymal Stromal Cells and Exert a Distinct Microenvironmental Impact on Normal and Leukemic Cells

Targeting the Osteoblast in Myelodysplasia and Acute Myeloid Leukemia

Osteoblast ablation reduces normal long-term hematopoietic stem cell self-renewal but accelerates leukemia development

IL-17A-Mediated Notch Signaling in Multiple Myeloma

Foxo1 Expressed in Osteoblasts Promotes the Leukemogenic Properties of β-Catenin By Activating Notch Signaling

Role of Stromal Cell-Mediated Notch Signaling in AML Resistance to Chemotherapy

Genomic Analisys of Notch Mutations in a Case of Alagille Syndrome with Acute Lymphoblastic Leukemia

Role Of Stromal Cell-Mediated Notch Signaling In Hematological Malignancies

Diverse Impact of Notch-1, Jagged-1 and Dll-1 Expression On Response to Treatment and Relapse Free Survival in Acute Myeloid Leukemia.

Intermittent in Vivo Parathyroid Hormone (PTH) Treatment Results in Jagged 1 (Jag 1) Dependent and Independent Effects On Hematopoietic Stem Cells (HSCs)

Bone Marrow Niche Attenuation by Non-Steroidal Anti-Inflammatory Drugs Mobilizes Hematopoietic Stem and Progenitor Cells by Differing Mechanisms

Vascular Pericytes Sustain Hematopoietic Stem Cells

The Complicated Network Structure and Activated Notch Signal Pathway in Embryo Heart of Mouse Provide the Favorable Microenvironment for HSCs Development and Proliferation During E10∼E12

Notch Repression by LRF Is Necessary for the Maintenance of Adult Hematopoietic Stem Cell Pool.

Impaired Osteogenic Differentiation of Mesenchymal Stem Cells Derived From Multiple Myeloma Patients Is Associated with a Failure In the Deactivation of the NOTCH Pathway

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American Society of Hematology

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ASH Publications

American Society of Hematology

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