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Journal Articles

Next-Generation FVIII Mimetic Shows Superior Effect in a FIX- and Fx-Humanized Mouse Model In Vivo

Carsten Dan Ley, PhD, Thomas Lindebo Holm, PhD, Daniel Elenius, PhD, Heidi Lindgreen Holmberg, PhD, Jais Rose Bjelke, PhD, Mette Loftager, PhD, Mette B Hermit, PhD, Ida Hilden, Stine L Kjellev, PhDDVM

Blood (2019) 134 (Supplement_1): 3631.

https://doi.org/10.1182/blood-2019-128159

Published: 2019

Journal Articles

Mitigation of Vascular Permeability Using Bradykinin Receptor Antagonist and Anti-Fibrinolytic Agent in Rats with Polytrauma and Hemorrhagic Shock

Xiaowu Wu, MD MSc, Daniel N. Darlington, PhD, Josue Garciamarcano, Bin Liu, BS, Jeffrey D Keesee, BS, James Bynum, PhD, Andrew P. Cap, MD PhD

Blood (2019) 134 (Supplement_1): 2345.

https://doi.org/10.1182/blood-2019-130278

Published: 2019

Journal Articles

Fast Onset of Action of Subcutaneously Administered Marzeptacog Alfa (Activated) Supports on-Demand Treatment in Hemophilia a Mice

Frank Del Greco, MBA, Linda Neuman, MD, Howard Levy, PhD MBBChir, Jill Reckless, Tom Knudsen, PhD DVM, Grant E. Blouse, PhD

Blood (2019) 134 (Supplement_1): 2420.

https://doi.org/10.1182/blood-2019-128971

Published: 2019

Journal Articles

Trauma Leads to a Rise in Intracellular cAMP and Adenylate Cyclase Activity in Rats

Daniel N Darlington, PhD, Bunyan Teng, PhD, Xiaowu Wu, MD MSc, Andrew P Cap, MD PhD

Blood (2018) 132 (Supplement 1): 1155.

https://doi.org/10.1182/blood-2018-99-114805

Published: 2018

Journal Articles

Intravascular Hemolysis Leads to Priapism Phenotype: Experimental Evidence

Fabio H Silva, Beatriz Pereira Bossarino, Fabiano B Calmasini, PhD, Eduardo Costa Alexandre, PhD, Fernando F. Costa, MD, PhD

Blood (2018) 132 (Supplement 1): 1076.

https://doi.org/10.1182/blood-2018-99-115513

Published: 2018

Journal Articles

Severe Trauma Leads to a Fall in Intracellular Triphosphates and a Rise in cAMP in Platelets

Daniel N Darlington, PhD, Xiaowu Wu, MD MSc, Andrew P. Cap, MD PhD

Blood (2017) 130 (Supplement 1): 2318.

https://doi.org/10.1182/blood.V130.Suppl_1.2318.2318

Published: 2017

Journal Articles

In Vivo Brain Redox Imaging in Transgenic-Knockout Sickle Mice

Min-Hui Cui, PhD, Seetharama Acharya, PhD, Henny Heisler Billett, MD, Craig A Branch, PhD MS

Blood (2017) 130 (Supplement 1): 2229.

https://doi.org/10.1182/blood.V130.Suppl_1.2229.2229

Published: 2017

Journal Articles

Intravascular Hemolysis Leads to Increased Esophagus Smooth Muscle Contractions in Mice: Implication for Dysphagia and Odynophagia

Fabio H Silva, PhD, Eduardo C Alexandre, PhD, Fabiano B Calmasini, PhD, Carla Fernanda Franco-Penteado, BSc, PhD, Edson Antunes, PhD, Kleber Yotsumoto Fertrin, MD PhD, Fernando Ferreira Costa, MD PhD

Blood (2017) 130 (Supplement 1): 3470.

https://doi.org/10.1182/blood.V130.Suppl_1.3470.3470

Published: 2017

Journal Articles

Platelets from Fresh and Cold-Stored Whole Blood Contribute to Clot Formation after Transfusion in Rats with Acute Traumatic Coagulopathy

Xiaowu Wu, MD MMSc, Robbie Montgomery, MS, Bin Liu, BS, Jeffrey D Keesee, BS, Avi Benov, MD, Daniel N Darlington, PhD, Andrew P Cap, MD PhD

Blood (2016) 128 (22): 1457.

https://doi.org/10.1182/blood.V128.22.1457.1457

Published: 2016

Journal Articles

24-Hour Profile of Microvascular Liver Perfusion in Sickle Cell Disease Mice Following Hypoxia-Induced Vaso-Occlusion

Keith Abe, B.S., Michael Wright, B.S., Derek Sim, PhD, Magdalena Alonso-Galicia, PhD, Katalin Kauser

Blood (2016) 128 (22): 1300.

https://doi.org/10.1182/blood.V128.22.1300.1300

Published: 2016

Journal Articles

VWF-FVIII Interactions Influence Hemostatic Thrombus Stability in Murine Models of Hemophilia Α and Type 2N VWD

Laura L Swystun, PhD, Courtney Dwyer, Kate Nesbitt, Kassandra Hebert, David Lillicrap, MD

Blood (2016) 128 (22): 1403.

https://doi.org/10.1182/blood.V128.22.1403.1403

Published: 2016

Journal Articles

Fetal Hemoglobin Improves Cerebral Blood Flow and Decreases Brain Inflammation in Transgenic- Sickle Mice

Min Hui Cui, PhD, Henny H Billett, MD, Sandra Suzuka, M.S., Kamalakar Ambadipudi, M.S., Caterina P. Minniti, MD, Seetharama Acharya, PhD, Craig A Branch, PhD

Blood (2016) 128 (22): 3639.

https://doi.org/10.1182/blood.V128.22.3639.3639

Published: 2016

Journal Articles

Novel Gene Therapy Strategy for Hemophilia a By Hydrodynamic Gene Delivery Combined with Non-Viral Piggybac Transposon Vector in Canine Model

Masashi Noda, DVM, Hideto Matsui, MD PhD, Yasunori Matsunari, MD, Sunao Ochi, DVM, Midori Shima, MD PhD, Yasushi Fukuoka, Takeshi Sato, MD, Hiroshi Anai, MD PhD, Kimihiko Kichikawa, MD PhD, Masanari Nakayama, DVM, PhD, Akitsu Hotta, PhD, Mitsuhiko Sugimoto, MD PhD

Blood (2015) 126 (23): 4419.

https://doi.org/10.1182/blood.V126.23.4419.4419

Published: 2015

Journal Articles

Cerebral Perfusion Patterns in Transgenic Murine Models of Sickle Cell Disease As Seen By MRI Is Reflective of Their Anemia Profile and Parallels the Human Disease

Craig A Branch, MS, PhD, Min-Hui Cui, PhD, Nicholas Branch, Seetharama Acharya

Blood (2015) 126 (23): 968.

https://doi.org/10.1182/blood.V126.23.968.968

Published: 2015

Journal Articles

Relevant Role of Von Willebrand Factor in Ischemia-Reperfusion Model of Acute Kidney Injury in Mice

Shiro Ono, Hideto Matsui, MD PhD, Masashi Noda, Shogo Kasuda, Yasunori Matsunari, MD, Noritaka Yada, Kenji Nishio, Mitsuhiko Sugimoto, MD PhD

Blood (2015) 126 (23): 2243.

https://doi.org/10.1182/blood.V126.23.2243.2243

Published: 2015

Journal Articles

Tissue-Specific Regulation of Iron Release in Response to Body Iron Status Under Erythropoietic Stimulation

Yukari Matsuo-Tezuka, Mariko Noguchi-Sasaki, PhD, Mitsue Kurasawa, Keigo Yorozu, PhD, Yasushi Shimonaka

Blood (2015) 126 (23): 2148.

https://doi.org/10.1182/blood.V126.23.2148.2148

Published: 2015

Journal Articles

Protection of Microvascular Liver Perfusion with 5-Hydroxymethylfurfural in Sickle Cell Disease Mice Following Hypoxia-Induced Vasoocclusion

Michael Wright, Derek Sim, Magdalena Alonso-Galicia, Katalin Kauser, Keith Abe

Blood (2015) 126 (23): 3382.

https://doi.org/10.1182/blood.V126.23.3382.3382

Published: 2015

Journal Articles

Surgical Control/Cure of 5TGM1 Murine Multiple Myeloma Model By Thyroparathyroidectomy

Maurizio Zangari, MD, Donghoon Yoon, PhD, Hanna Yoo, MS, Young Sik Kim, PhD

Blood (2014) 124 (21): 3387.

https://doi.org/10.1182/blood.V124.21.3387.3387

Published: 2014

Journal Articles

Discovery of a Novel, Potent, Selective and Injectable Small Molecule Inhibitor of Blood Coagulation Factor XIa, ONO-8610539: in Vitro and in Vivo Pharmacological Profiles

Masashi Gohda, PhD, Masaru Sakai, Kenji Tanaka, Tetsuya Hagio, PhD, Keizo Suzuki, Sho Koyama, Takehiro Ono, Ai Hashimoto, Hidekazu Matsuya, Yasushi Hirota, PhD, Takashi Kondo, PhD, Taihei Nishiyama, PhD, Akira Imagawa, Kazuhito Kawabata, PhD

Blood (2014) 124 (21): 1542.

https://doi.org/10.1182/blood.V124.21.1542.1542

Published: 2014

Journal Articles

Whole Blood Stored at 4°C for 7 Days Is Equivalent to Fresh Whole Blood for Resuscitation of Severe Polytrauma

Daniel N Darlington, PhD, Jacob Chen, MD, Xiaowu Wu, MD, Jeffery Keesee, BS, Bin Liu, BS, Andrew P Cap, MDPhD

Blood (2014) 124 (21): 1558.

https://doi.org/10.1182/blood.V124.21.1558.1558

Published: 2014

NARROW

Next-Generation FVIII Mimetic Shows Superior Effect in a FIX- and Fx-Humanized Mouse Model In Vivo

Mitigation of Vascular Permeability Using Bradykinin Receptor Antagonist and Anti-Fibrinolytic Agent in Rats with Polytrauma and Hemorrhagic Shock

Fast Onset of Action of Subcutaneously Administered Marzeptacog Alfa (Activated) Supports on-Demand Treatment in Hemophilia a Mice

Trauma Leads to a Rise in Intracellular cAMP and Adenylate Cyclase Activity in Rats

Intravascular Hemolysis Leads to Priapism Phenotype: Experimental Evidence

Severe Trauma Leads to a Fall in Intracellular Triphosphates and a Rise in cAMP in Platelets

In Vivo Brain Redox Imaging in Transgenic-Knockout Sickle Mice

Intravascular Hemolysis Leads to Increased Esophagus Smooth Muscle Contractions in Mice: Implication for Dysphagia and Odynophagia

Platelets from Fresh and Cold-Stored Whole Blood Contribute to Clot Formation after Transfusion in Rats with Acute Traumatic Coagulopathy

24-Hour Profile of Microvascular Liver Perfusion in Sickle Cell Disease Mice Following Hypoxia-Induced Vaso-Occlusion

VWF-FVIII Interactions Influence Hemostatic Thrombus Stability in Murine Models of Hemophilia Α and Type 2N VWD

Fetal Hemoglobin Improves Cerebral Blood Flow and Decreases Brain Inflammation in Transgenic- Sickle Mice

Novel Gene Therapy Strategy for Hemophilia a By Hydrodynamic Gene Delivery Combined with Non-Viral Piggybac Transposon Vector in Canine Model

Cerebral Perfusion Patterns in Transgenic Murine Models of Sickle Cell Disease As Seen By MRI Is Reflective of Their Anemia Profile and Parallels the Human Disease

Relevant Role of Von Willebrand Factor in Ischemia-Reperfusion Model of Acute Kidney Injury in Mice

Tissue-Specific Regulation of Iron Release in Response to Body Iron Status Under Erythropoietic Stimulation

Protection of Microvascular Liver Perfusion with 5-Hydroxymethylfurfural in Sickle Cell Disease Mice Following Hypoxia-Induced Vasoocclusion

Surgical Control/Cure of 5TGM1 Murine Multiple Myeloma Model By Thyroparathyroidectomy

Discovery of a Novel, Potent, Selective and Injectable Small Molecule Inhibitor of Blood Coagulation Factor XIa, ONO-8610539: in Vitro and in Vivo Pharmacological Profiles

Whole Blood Stored at 4°C for 7 Days Is Equivalent to Fresh Whole Blood for Resuscitation of Severe Polytrauma

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American Society of Hematology

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