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Journal Articles

Identification of Optimized Peptide Nucleic Acid (PNA) Designs for Nuclease-Free Gene Editing in Sickle Cell Disease Hematopoietic Stem and Progenitor Cells (HSPCs)

Allen Ebens, PhD, Andrew Curd, B.Sc., Derek Sim, PhD, Elias Quijano, B.Sc., Florence Tam, M.Sc., James Coull, PhD,, Lily Huang, M.Sc., Mark Hayes, PhD, Marshall Fordyce, MD, Robert Pearson, B.Sc., Susan Whoriskey, PhD, Tumul Srivastava, PhD, Xiaojun Li, MD, Zhen Zhang, PhD

Blood (2019) 134 (Supplement_1): 4645.

https://doi.org/10.1182/blood-2019-127538

Published: 2019

Journal Articles

24-Hour Profile of Microvascular Liver Perfusion in Sickle Cell Disease Mice Following Hypoxia-Induced Vaso-Occlusion

Keith Abe, B.S., Michael Wright, B.S., Derek Sim, PhD, Magdalena Alonso-Galicia, PhD, Katalin Kauser

Blood (2016) 128 (22): 1300.

https://doi.org/10.1182/blood.V128.22.1300.1300

Published: 2016

Journal Articles

Hemophilia a Clots Generated with Recombinant Factor VIIa Differed in Structure and Composition from Those Formed with Factor VIII

Lilley Leong, Irina N. Chernysh, Yifan Xu, Cornell Mallari, Billy Wong, Derek Sim, Adam Cuker, MD MS, Joseph Marturano, Thomas Lowery, Katalin Kauser, John W. Weisel

Blood (2016) 128 (22): 3798.

https://doi.org/10.1182/blood.V128.22.3798.3798

Published: 2016

Journal Articles

Targeted Inhibition of Activated Protein C Anticoagulant Activity By Monoclonal Antibody HAPC1573 for Treatment of Hemophilia

Xiao-Yan Zhao, PhD, Subramanian Yegneswaran, PhD, Maxine Bauzon, Derek Sim, Chandra Patel, PhD, Doug Schneider, Kirk McLean, Ying Zhu, MD, Xiaoqiao Jiang, Vince Evans, Jian-Ming Gu, PhD, Inge Ivens, PhD, Jun Xu, PhD, Peter Wolfgang Bringmann, PhD, Katalin Kauser, Charles Esmon, PhD

Blood (2016) 128 (22): 80.

https://doi.org/10.1182/blood.V128.22.80.80

Published: 2016

Journal Articles

A Factor VIII with Site-Specific Pegylation Attenuates the Binding with Inhibitors Results in the Retention of Hemostatic Effect

Koji Yada, MDPhD, Keiji Nogami, MDPhD, Chandra Patel, Derek Sim, Katalin Kauser, MD PhD, Midori Shima, MD PhD

Blood (2015) 126 (23): 1076.

https://doi.org/10.1182/blood.V126.23.1076.1076

Published: 2015

Journal Articles

Acute Efficacy of a Novel Anti-Tissue Factor Pathway Inhibitor Antibody BAY 1093884 in Hemophilia A Mouse Severe Tail Bleeding

Yifan Xu, Maria Koellenberger, Volker Laux, Katalin Kauser, Derek Sim, PhD

Blood (2015) 126 (23): 3500.

https://doi.org/10.1182/blood.V126.23.3500.3500

Published: 2015

Journal Articles

Protection of Microvascular Liver Perfusion with 5-Hydroxymethylfurfural in Sickle Cell Disease Mice Following Hypoxia-Induced Vasoocclusion

Michael Wright, Derek Sim, Magdalena Alonso-Galicia, Katalin Kauser, Keith Abe

Blood (2015) 126 (23): 3382.

https://doi.org/10.1182/blood.V126.23.3382.3382

Published: 2015

Journal Articles

Characterization of a High-Affinity Fully Human IgG2 Antibody Against Tissue Factor Pathway Inhibitor As a Bypass Agent for the Treatment of Hemophilia

Maxine Bauzon, Bing Liu, Joanna Grudzinska-Goebel, Jan Tebbe, Junliang Pan, Jill Cifrese, Zhuozhi Wang, Derek Sim

Blood (2015) 126 (23): 3513.

https://doi.org/10.1182/blood.V126.23.3513.3513

Published: 2015

Journal Articles

Noncovalent stabilization of the factor VIII A2 domain enhances efficacy in hemophilia A mouse vascular injury models

Lilley Leong, Derek Sim, Chandra Patel, Katherine Tran, Perry Liu, Elena Ho, Thomas Thompson, Peter J. Kretschmer, Hironao Wakabayashi, Philip J. Fay, John E. Murphy

Blood (2015) 125 (2): 392–398.

https://doi.org/10.1182/blood-2014-02-555656

Published: 2015

Includes: Supplemental data

Journal Articles

Critical role for Syk in responses to vascular injury

Blood (2011) 118 (18): 5000–5010.

https://doi.org/10.1182/blood-2011-06-360743

Published: 2011

Includes: Supplemental data

Journal Articles

A Chemical Genetic Analysis of Platelet Activation Identifies An Antithrombotic Allosteric Modulator That Acts through Helix 8 of Par1

Louisa M. Dowal, Derek Sim, James R Dilks, Price Blair, Sarah Beaudry, Bradley Denker, George Koukos, Athan Kuliopulos, Robert Flaumenhaft

Blood (2010) 116 (21): 483.

https://doi.org/10.1182/blood.V116.21.483.483

Published: 2010

NARROW

Identification of Optimized Peptide Nucleic Acid (PNA) Designs for Nuclease-Free Gene Editing in Sickle Cell Disease Hematopoietic Stem and Progenitor Cells (HSPCs)

24-Hour Profile of Microvascular Liver Perfusion in Sickle Cell Disease Mice Following Hypoxia-Induced Vaso-Occlusion

Hemophilia a Clots Generated with Recombinant Factor VIIa Differed in Structure and Composition from Those Formed with Factor VIII

Targeted Inhibition of Activated Protein C Anticoagulant Activity By Monoclonal Antibody HAPC1573 for Treatment of Hemophilia

A Factor VIII with Site-Specific Pegylation Attenuates the Binding with Inhibitors Results in the Retention of Hemostatic Effect

Acute Efficacy of a Novel Anti-Tissue Factor Pathway Inhibitor Antibody BAY 1093884 in Hemophilia A Mouse Severe Tail Bleeding

Protection of Microvascular Liver Perfusion with 5-Hydroxymethylfurfural in Sickle Cell Disease Mice Following Hypoxia-Induced Vasoocclusion

Characterization of a High-Affinity Fully Human IgG2 Antibody Against Tissue Factor Pathway Inhibitor As a Bypass Agent for the Treatment of Hemophilia

Noncovalent stabilization of the factor VIII A2 domain enhances efficacy in hemophilia A mouse vascular injury models

Critical role for Syk in responses to vascular injury

A Chemical Genetic Analysis of Platelet Activation Identifies An Antithrombotic Allosteric Modulator That Acts through Helix 8 of Par1

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American Society of Hematology

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ASH Publications

American Society of Hematology

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