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Journal Articles

Pre-Clinical Characterization of VGA039, an Anti-Protein S Monoclonal Antibody Being Developed As a Universal Hemostatic Agent for Various Bleeding Disorders

Lilley Leong, Tony Byun, Benjamin Kim, Ian Huck, Abel Silva, Joanne Chan, Young Cho, John Liu, Christopher J. Horvath, Stephen J. Moore, Sandip Panicker
Journal: Blood
Blood (2022) 140 (Supplement 1): 1666–1667.
https://doi.org/10.1182/blood-2022-170245
Published: 2022
Journal Articles

Bay 94-9027 Can be Accurately Measured across Regions with Appropriate One-Stage Assay Reagent Use

Rajiv K. Pruthi, M.B.B.S., Donna D. Castellone, Nikki Church, MD MBA, Lilley Leong, PhD, Steve Kitchen
Journal: Blood
Blood (2018) 132 (Supplement 1): 2481.
https://doi.org/10.1182/blood-2018-99-113493
Published: 2018
Journal Articles

Hemophilia a Clots Generated with Recombinant Factor VIIa Differed in Structure and Composition from Those Formed with Factor VIII

Lilley Leong, Irina N. Chernysh, Yifan Xu, Cornell Mallari, Billy Wong, Derek Sim, Adam Cuker, MD MS, Joseph Marturano, Thomas Lowery, Katalin Kauser, John W. Weisel
Journal: Blood
Blood (2016) 128 (22): 3798.
https://doi.org/10.1182/blood.V128.22.3798.3798
Published: 2016
Journal Articles

Bay 94-9027, a Site-Specifically Pegylated Recombinant Factor VIII: Preliminary Results from an International Comparative Laboratory Field Study

Nikki Church, Lilley Leong, Yvonne Katterle, Yadagiri Rao Danda, Hannes-Friedrich Ulbrich, Iris Noerenberg, Stefan Bruns, Lisa A. Michaels
Journal: Blood
Blood (2016) 128 (22): 2587.
https://doi.org/10.1182/blood.V128.22.2587.2587
Published: 2016
Journal Articles

Noncovalent stabilization of the factor VIII A2 domain enhances efficacy in hemophilia A mouse vascular injury models

Lilley Leong, Derek Sim, Chandra Patel, Katherine Tran, Perry Liu, Elena Ho, Thomas Thompson, Peter J. Kretschmer, Hironao Wakabayashi, Philip J. Fay, John E. Murphy
Journal: Blood
Blood (2015) 125 (2): 392–398.
https://doi.org/10.1182/blood-2014-02-555656
Published: 2015
Includes: Supplemental data
Journal Articles

Site-Directed Pegylation of BDD FVIII (BAY 94-9027) Does Not Alter the Ability of the Molecule to Generate Thrombin, Activate Factor X or Become Inactivated By Activated Protein C

Subramanian Yegneswaran, PhD, Xiaoqiao Jiang, BS, Pooja Yesantharao, Ji-Yun Kim, PhD, Lilley Leong, PhD MS, Derek S Sim, PhD, Chandra Patel, PhD, Katalin Zsofia Kauser, PhD MD DSc
Journal: Blood
Blood (2014) 124 (21): 1492.
https://doi.org/10.1182/blood.V124.21.1492.1492
Published: 2014
Journal Articles

Reduced Polyethylene Glycol-Conjugated B-Domain–Deleted Factor VIII (PEG-BDD-FVIII) Clearance: Selective Peg Steric Modulation without Affecting Potency

Eric Blasko, Lilley Leong, PhD MS, Derek S Sim, PhD, Liang Tang, PhD, Elena Ho, Jim Wu, Katalin Zsofia Kauser, PhD MD DSc, Babu Subramanyam
Journal: Blood
Blood (2014) 124 (21): 1471.
https://doi.org/10.1182/blood.V124.21.1471.1471
Published: 2014
Journal Articles

Waveform Analysis Extends the Capabilities of aPTT and PT Clotting Assays for Detecting Factor Deficiency and Monitoring Procoagulant Drug Therapy

Lilley Leong, PhD, MS, Xiaoqiao Jiang, BS, Jill Cifrese, MS, John E. Murphy, PhD, Jesper Haaning, PhD, Timothy Myles, PhD
Journal: Blood
Blood (2011) 118 (21): 1205.
https://doi.org/10.1182/blood.V118.21.1205.1205
Published: 2011