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Journal Articles

Manufacture and In Vivo Support of Gene-Edited, Regulatory-like, T-Cells (edTreg) Using a Synthetic IL2 Receptor

Gene I. Uenishi, PhD, Cornell Mallari, Luis Gamboa, Samuel West, Chester Jacobs, Noelle Dahl, Greg Boucher, Samantha Chin, Rangoli Aeran, Dariusz Wodziak, Simon Gebremeskel, Karen Vo, PhD, Cade E. Ito, Laura Smith, Chandra Patel, PhD, Keith Abe, PhD, Basha Stankovich, PhD, Karen Sommer, PhD, Troy R. Torgerson, MD PhD, David J. Rawlings, MD, Andrew M. Scharenberg, MD, Greg J. Cost, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3355.
https://doi.org/10.1182/blood-2019-130945
Published: 2019
Journal Articles

Targeted Inhibition of Activated Protein C Anticoagulant Activity By Monoclonal Antibody HAPC1573 for Treatment of Hemophilia

Xiao-Yan Zhao, PhD, Subramanian Yegneswaran, PhD, Maxine Bauzon, Derek Sim, Chandra Patel, PhD, Doug Schneider, Kirk McLean, Ying Zhu, MD, Xiaoqiao Jiang, Vince Evans, Jian-Ming Gu, PhD, Inge Ivens, PhD, Jun Xu, PhD, Peter Wolfgang Bringmann, PhD, Katalin Kauser, Charles Esmon, PhD
Journal: Blood
Blood (2016) 128 (22): 80.
https://doi.org/10.1182/blood.V128.22.80.80
Published: 2016
Journal Articles

Plasma Tissue Factor Pathway Inhibitor (TFPI) Levels in Healthy Subjects and Patients with Hemophilia A and B

Jian-Ming Gu, Chandra Patel, Katalin Kauser
Journal: Blood
Blood (2015) 126 (23): 4672.
https://doi.org/10.1182/blood.V126.23.4672.4672
Published: 2015
Journal Articles

A Factor VIII with Site-Specific Pegylation Attenuates the Binding with Inhibitors Results in the Retention of Hemostatic Effect

Koji Yada, MDPhD, Keiji Nogami, MDPhD, Chandra Patel, Derek Sim, Katalin Kauser, MD PhD, Midori Shima, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1076.
https://doi.org/10.1182/blood.V126.23.1076.1076
Published: 2015
Journal Articles

Noncovalent stabilization of the factor VIII A2 domain enhances efficacy in hemophilia A mouse vascular injury models

Lilley Leong, Derek Sim, Chandra Patel, Katherine Tran, Perry Liu, Elena Ho, Thomas Thompson, Peter J. Kretschmer, Hironao Wakabayashi, Philip J. Fay, John E. Murphy
Journal: Blood
Blood (2015) 125 (2): 392–398.
https://doi.org/10.1182/blood-2014-02-555656
Published: 2015
Includes: Supplemental data
Journal Articles

Site-Directed Pegylation of BDD FVIII (BAY 94-9027) Does Not Alter the Ability of the Molecule to Generate Thrombin, Activate Factor X or Become Inactivated By Activated Protein C

Subramanian Yegneswaran, PhD, Xiaoqiao Jiang, BS, Pooja Yesantharao, Ji-Yun Kim, PhD, Lilley Leong, PhD MS, Derek S Sim, PhD, Chandra Patel, PhD, Katalin Zsofia Kauser, PhD MD DSc
Journal: Blood
Blood (2014) 124 (21): 1492.
https://doi.org/10.1182/blood.V124.21.1492.1492
Published: 2014
Journal Articles

Glycopegylated Factor IX Enables Prolonged Efficacy After Subcutaneous Injection But Requires a Higher Than Expected Plasma Activity To Prevent Bleeding In Hemophilia B Mice

Derek S Sim, Alan Brooks, Cornell Mallari, Yifan Xu, Rick I Feldman, Doug Schneider, Chandra Patel, Eric Blasko, Elena Ho, Yan Su, Bing Liu, Volker Laux, John E Murphy
Journal: Blood
Blood (2013) 122 (21): 1104.
https://doi.org/10.1182/blood.V122.21.1104.1104
Published: 2013
Journal Articles

Enhanced efficacy of recombinant FVIII in noncovalent complex with PEGylated liposome in hemophilia A mice

Junliang Pan, Tongyao Liu, Ji-Yun Kim, Daguang Zhu, Chandra Patel, Zhi-Hua Cui, Xin Zhang, James O. Newgren, Aaron Reames, Dodie Canivel, Gary Jesmok, Glenn F. Pierce, Jurg M. Sommer, Haiyan Jiang
Journal: Blood
Blood (2009) 114 (13): 2802–2811.
https://doi.org/10.1182/blood-2009-03-212423
Published: 2009
Journal Articles

Enhanced Efficacy of Recombinant Factor VIII in Non-Covalent Complex with PEGylated Liposome in Hemophilia A Mice.

Junliang Pan, PhD, Tongyao Liu, Ji-Yun Kim, PhD, Chandra Patel, PhD, Jim Newgren, MS, Jurg Sommer, PhD, Glenn Pierce, MD, PhD, Haiyan Jiang, PhD
Journal: Blood
Blood (2007) 110 (11): 3149.
https://doi.org/10.1182/blood.V110.11.3149.3149
Published: 2007