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Journal Articles

Statins Enhance Killing of Multiple Myeloma Cells By the BCL-2 Inhibitor Venetoclax and the MCL-1 Inhibitor S63845

David Fruman, PhD, Dennis Juarez, B.S., Grace Diep, Undergraduate, Falisha Nguyen, Undergraduate, Vikas A. Gupta, MD PhD, Lawrence H. Boise, PhD

Blood (2019) 134 (Supplement_1): 4413.

https://doi.org/10.1182/blood-2019-131218

Published: 2019

Journal Articles

Adaptation to Metabolic Stress By Mondoα in Common B-Cell Acute Lymphoblastic Leukemia

Alexandra Sipol, Andreas Petry, Erik Hameister, Agnes Görlach, Jürgen Ruland, Stefan Burdach, Poul Sorensen

Blood (2018) 132 (Supplement 1): 3888.

https://doi.org/10.1182/blood-2018-99-114014

Published: 2018

Journal Articles

Atorvastatin Restored the CD4 + T Cell Homeostasis By Regulating the Axis of Effector T Cells and Regulatory T Cells in Immune Thrombocytopenia

Pengcheng Xu, Yajing Zhao, BA, MD, Ming Hou, MD, Panpan Han

Blood (2018) 132 (Supplement 1): 132.

https://doi.org/10.1182/blood-2018-99-114690

Published: 2018

Journal Articles

Azacitidine and Romidepsin Synergize to Induce Expression of Cancer Testes Antigens (CTA) and Shift Peripheral T-Cell Lymphoma (PTCL) Cell Lines Toward a Th1-like Phenotype

Cristina Kinahan, BS, Luigi Scotto, PhD, Owen A. O'Connor, MD, PhD

Blood (2018) 132 (Supplement 1): 2845.

https://doi.org/10.1182/blood-2018-99-117344

Published: 2018

Journal Articles

Statin Use Is Associated with Decreased Mortality in Multiple Myeloma— a SEER Medicare Study

Shivaprasad Manjappa, MD, Mark A. Fiala, BS, Pavan Kumar Bhamidipati, MBBS, MD, Keith E. Stockerl-Goldstein, MD, Mark A. Schroeder, MD, Armin Ghobadi, MD, Ravi Vij, MDMBA, Tanya M. Wildes, MDMSCI

Blood (2017) 130 (Supplement 1): 1860.

https://doi.org/10.1182/blood.V130.Suppl_1.1860.1860

Published: 2017

Journal Articles

Statins Potentiate the Cytotoxic Effect of ABT-199 in Diffuse Large B Cell Lymphoma

David A. Fruman, PhD, Jong-Hoon Scott Lee, B.S., Thanh-Trang T Vo, PhD, Shruti Bhatt, PhD, Jonathan H. Schatz, MD, Anthony Letai, MD PhD

Blood (2016) 128 (22): 3969.

https://doi.org/10.1182/blood.V128.22.3969.3969

Published: 2016

Journal Articles

A Genomic Predictive Signature for Rigosertib in Lower Risk MDS Derived By Integrating Clinical Response, Mechanism of Action Data and Simulation

Steven M. Fruchtman, MD, Abdullah Mahmood Ali, PhD, Michael E. Petrone, MD MPH, Patrick Simon Zbyszewski, MBA, Benjamin Hoffman, PhD, Shireen Vali, PhD, Neeraj Kumar Singh, Shahabuddin Usmani, Himanshu Grover, Taher Abbasi, Azra Raza, MD

Blood (2016) 128 (22): 5535.

https://doi.org/10.1182/blood.V128.22.5535.5535

Published: 2016

Journal Articles

Effects of Isoprenoid Biosynthetic Pathway Inhibition on Glucose Uptake in Myeloma Cells

Kaitlyn M. Dykstra, PhD, Sarah A. Holstein, MD PhD

Blood (2016) 128 (22): 3300.

https://doi.org/10.1182/blood.V128.22.3300.3300

Published: 2016

Journal Articles

Gamma-Tocotrienol and Simvastatin Synergistically Induce Cytotoxicity In Leukemia Cell Lines, K-562 and HL-60

Ko Maung, Victoria Palau, Janet Lightner, Marianne Brannon, Koyamangalath Krishnan, MD

Blood (2013) 122 (21): 4927.

https://doi.org/10.1182/blood.V122.21.4927.4927

Published: 2013

Journal Articles

Dissecting The Effects Of Isoprenoid Pathway Inhibition On Hemostasis and Thrombosis: Differential Effects Of Atorvastatin and Digeranyl Bisphosphonate In Hypercholesterolemic Mice

Neha Bhasin, MD, Jeff Stevens, PhD, Masaru Niki, MD, PhD, Huaxiang Tong, PhD, Craig Kuder, PhD, Raymond J. Hohl, MD, PhD, Steven R Lentz, MD, PhD

Blood (2013) 122 (21): 2378.

https://doi.org/10.1182/blood.V122.21.2378.2378

Published: 2013

Journal Articles

Statins Use Improves the Clinical Outcomes of Salvage Therapy in Relapsed/Refractory CLL

Long Xuan Trinh, MD, Young Kwang Chae, MD, MPH, Preetesh Jain, MD, DM, PhD, Ohad Benjamini, MD, Xuemei Wang, MS, Susan Lerner, MS, William G. Wierda, MD, Ph.D., Zeev Estrov, MD, PhD, Michael J. Keating, MD

Blood (2012) 120 (21): 3931.

https://doi.org/10.1182/blood.V120.21.3931.3931

Published: 2012

Journal Articles

Niche-Based Screening Reveals Leukemia Stem Cell Specific Therapeutics

Blood (2011) 118 (21): 760.

https://doi.org/10.1182/blood.V118.21.760.760

Published: 2011

Journal Articles

A Mechanistic Rationale for the Use of Statins to Enhance JAK Inhibitor Therapy in MPNs

Lori N. Griner, Kathy L. McGraw, Joseph O. Johnson, Alan F. List, MD, Gary W. Reuther

Blood (2011) 118 (21): 2816.

https://doi.org/10.1182/blood.V118.21.2816.2816

Published: 2011

Journal Articles

12/15-Lipoxygenase gene knockout severely impairs ischemia-induced angiogenesis due to lack of Rac1 farnesylation

Nikhlesh K. Singh, Venkatesh Kundumani-Sridharan, Gadiparthi N. Rao

Blood (2011) 118 (20): 5701–5712.

https://doi.org/10.1182/blood-2011-04-347468

Published: 2011

Journal Articles

In Vivo Treatment of AML Patients with High-Dose Simvastatin Inhibits Geranylgeranylation In AML Cells

Karen van der Weide, Susan D.P.W.M. de Jonge-Peeters, Gerwin A. Huls, MD, PhD, Rudolf S.N. Fehrmann, Jan J. Schuringa, PhD, Folkert Kuipers, PhD, Elisabeth G.E. de Vries, MD, PhD, Edo Vellenga, MD, PhD

Blood (2010) 116 (21): 3280.

https://doi.org/10.1182/blood.V116.21.3280.3280

Published: 2010

Journal Articles

Platelet Tissue Factor Activity In Patients with Hypercholesterolemia: Modulation of Procoagulant Activity by Statins

Olga Panes, Mónica Acevedo, M.D., Valeria Matus, PhD, Claudia G. Sáez, PhD, Jaime Pereira, MD, Diego Mezzano, MD

Blood (2010) 116 (21): 156.

https://doi.org/10.1182/blood.V116.21.156.156

Published: 2010

Journal Articles

Association of Gene-Environment Interactions with Venous Thromboembolism (VTE): A Pathway-Directed Candidate-Gene Case-Control Study

John A. Heit, M.D., Sebastian M. Armasu, Tanya Petterson, David N. Rider, Julie M Cunningham, PhD, Mariza de Andrade, PhD

Blood (2010) 116 (21): 480.

https://doi.org/10.1182/blood.V116.21.480.480

Published: 2010

Journal Articles

Exploiting the mevalonate pathway to distinguish statin-sensitive multiple myeloma

James W. Clendening, Aleksandra Pandyra, Zhihua Li, Paul C. Boutros, Anna Martirosyan, Richard Lehner, Igor Jurisica, Suzanne Trudel, Linda Z. Penn

Blood (2010) 115 (23): 4787–4797.

https://doi.org/10.1182/blood-2009-07-230508

Published: 2010

Includes: Supplemental data

Journal Articles

Association of Gene-Gene Interactions with Venous Thromboembolism (VTE): A Pathway-Directed Candidate-Gene Case-Control Study.

John A. Heit, M.D., Sebastian M. Armasu, M.S., Tanya M. Petterson, M.S., David N. Rider, Julie M. Cunningham, Ph.D., Mariza de Andrade, Ph.D.

Blood (2009) 114 (22): 150.

https://doi.org/10.1182/blood.V114.22.150.150

Published: 2009

Journal Articles

Heterogeneity in Simvastatin-Induced Cytotoxicity in AML Is Related to Differential Ras-Isoprenylation, Rather Than to Blockade of Cholesterol Synthesis.

Karen van der Weide, Patrick M. Korthuis, Folkert Kuipers, Elisabeth G.E. de Vries, Edo Vellenga

Blood (2009) 114 (22): 1718.

https://doi.org/10.1182/blood.V114.22.1718.1718

Published: 2009

NARROW

Statins Enhance Killing of Multiple Myeloma Cells By the BCL-2 Inhibitor Venetoclax and the MCL-1 Inhibitor S63845

Adaptation to Metabolic Stress By Mondoα in Common B-Cell Acute Lymphoblastic Leukemia

Atorvastatin Restored the CD4 + T Cell Homeostasis By Regulating the Axis of Effector T Cells and Regulatory T Cells in Immune Thrombocytopenia

Azacitidine and Romidepsin Synergize to Induce Expression of Cancer Testes Antigens (CTA) and Shift Peripheral T-Cell Lymphoma (PTCL) Cell Lines Toward a Th1-like Phenotype

Statin Use Is Associated with Decreased Mortality in Multiple Myeloma— a SEER Medicare Study

Statins Potentiate the Cytotoxic Effect of ABT-199 in Diffuse Large B Cell Lymphoma

A Genomic Predictive Signature for Rigosertib in Lower Risk MDS Derived By Integrating Clinical Response, Mechanism of Action Data and Simulation

Effects of Isoprenoid Biosynthetic Pathway Inhibition on Glucose Uptake in Myeloma Cells

Gamma-Tocotrienol and Simvastatin Synergistically Induce Cytotoxicity In Leukemia Cell Lines, K-562 and HL-60

Dissecting The Effects Of Isoprenoid Pathway Inhibition On Hemostasis and Thrombosis: Differential Effects Of Atorvastatin and Digeranyl Bisphosphonate In Hypercholesterolemic Mice

Statins Use Improves the Clinical Outcomes of Salvage Therapy in Relapsed/Refractory CLL

Niche-Based Screening Reveals Leukemia Stem Cell Specific Therapeutics

A Mechanistic Rationale for the Use of Statins to Enhance JAK Inhibitor Therapy in MPNs

12/15-Lipoxygenase gene knockout severely impairs ischemia-induced angiogenesis due to lack of Rac1 farnesylation

In Vivo Treatment of AML Patients with High-Dose Simvastatin Inhibits Geranylgeranylation In AML Cells

Platelet Tissue Factor Activity In Patients with Hypercholesterolemia: Modulation of Procoagulant Activity by Statins

Association of Gene-Environment Interactions with Venous Thromboembolism (VTE): A Pathway-Directed Candidate-Gene Case-Control Study

Exploiting the mevalonate pathway to distinguish statin-sensitive multiple myeloma

Association of Gene-Gene Interactions with Venous Thromboembolism (VTE): A Pathway-Directed Candidate-Gene Case-Control Study.

Heterogeneity in Simvastatin-Induced Cytotoxicity in AML Is Related to Differential Ras-Isoprenylation, Rather Than to Blockade of Cholesterol Synthesis.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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