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Journal Articles

Gpibα Engagement Induces Activation of Human Platelet TF and Association with Constitutively Platelet Surface-Bound FVIIa

Olga Panes, Biochemist, M. Francisca Becerra, Biochemist, Roger Valle, Biochemist, Claudia G Sáez, PhD, Patricia Hidalgo, MT, Jaime Pereira, MD, Jennifer Royce, Wolfram Ruf, MD, PhD, Diego Mezzano, MD

Blood (2019) 134 (Supplement_1): 2337.

https://doi.org/10.1182/blood-2019-126359

Published: 2019

Journal Articles

Platelet Tissue Factor Activity Is Specifically Induced By Gpib Activation Pathway, Independent of GPVI, α IIb β and Protein Disulfide Isomerase Activities

Olga Panes, BM, BCh, Valeria Matus, PhD, Claudia G Sáez, PhD, Jaime Pereira, MD, Luz María Pozo, BCh, Diego Mezzano, MD

Blood (2017) 130 (Supplement 1): 2305.

https://doi.org/10.1182/blood.V130.Suppl_1.2305.2305

Published: 2017

Journal Articles

GPIbα Activation Triggers Platelet Tissue Factor/FVIIa-Dependent Procoagulant Activity, Which Is Dampened By Platelet Secreted TFPI and Protein S. Novel Platelet-Based Model of Hemostasis

Olga Panes, César González, Gustavo Soto, Jaime Pereira, MD, Valeria Matus, PhD, Claudia G. Sáez, PhD, Patricia Hidalgo, Diego Mezzano, MD

Blood (2014) 124 (21): 1430.

https://doi.org/10.1182/blood.V124.21.1430.1430

Published: 2014

Journal Articles

Tissue Factor-Dependent Pro-Coagulant Activity Of Human Platelets Is Directly Related To Membrane Cholesterol Content. Rosuvastatin, But Not Atorvastatin, Reduces The Platelet Cholesterol, Tissue Factor Protein and Clotting Activity In Hypercholesterolemic Patients

Olga Panes, Juan P. Valderas, M.D., Mónica Acevedo, M.D., Susana Contreras, Jaime Pereira, M.D., Attilio Rigotti, M.D., PhD., Diego Mezzano, M.D.

Blood (2013) 122 (21): 34.

https://doi.org/10.1182/blood.V122.21.34.34

Published: 2013

Journal Articles

Platelet Glycoprotein VI: An Adenine Insertion in Exon 6 Generates a Truncated Form of the Protein Associated with Bleeding Disorder in 4 Chilean Unrelated Patients

Valeria Matus, PhD, José Guillermo Valenzuela, Claudia G Sáez, PhD, Patricia Hidalgo, Olga Panes, Jaime Pereira, M.D., Diego Mezzano, M.D.

Blood (2012) 120 (21): 3302.

https://doi.org/10.1182/blood.V120.21.3302.3302

Published: 2012

Journal Articles

Circulating Human Platelets Express LRP-1 and uPAR mRNAs and Synthesize the Proteins: The Complex LRP-1, uPAR, PAI-1 and uPA Play a Role in Modulating Fibrinolysis in Platelet-Rich Thrombi

Olga Panes, Valeria Matus, PhD, César González, Claudia G Sáez, PhD, Jaime Pereira, M.D., Diego Mezzano, M.D.

Blood (2012) 120 (21): 1116.

https://doi.org/10.1182/blood.V120.21.1116.1116

Published: 2012

Journal Articles

Platelet Tissue Factor Activity In Patients with Hypercholesterolemia: Modulation of Procoagulant Activity by Statins

Olga Panes, Mónica Acevedo, M.D., Valeria Matus, PhD, Claudia G. Sáez, PhD, Jaime Pereira, MD, Diego Mezzano, MD

Blood (2010) 116 (21): 156.

https://doi.org/10.1182/blood.V116.21.156.156

Published: 2010

Journal Articles

Platelet Tissue Factor: Fast and Specific Clotting Activation Pathway Mediated by VWF-GPIba Interaction and Platelet Membrane FVII. Human Platelets Contain All the Components for Assembling the Prothrombinase Complex and Their Procoagulant Function Is Independent of Aggregation/Secretion and GPVI Function.

Olga Panes, Valeria Matus, PhD, Claudia G. Sáaez, PhD, Jaime Pereira, MD, Diego Mezzano, MD

Blood (2009) 114 (22): 3000.

https://doi.org/10.1182/blood.V114.22.3000.3000

Published: 2009

Journal Articles

Platelet Tissue Factor: Expression of Pro-Coagulant Activity depends on Gpibα Activation and Signaling through Lyn-Mediated Phosphorylation. A Platelet-Based Model of Hemostasis

Olga Panes, Paula Ibarra, Valeria Matus, PhD, Claudia G. Sáez, PhD, Jaime Pereira, MD, Diego Mezzano, MD

Blood (2008) 112 (11): 113.

https://doi.org/10.1182/blood.V112.11.113.113

Published: 2008

Journal Articles

Human Platelets Express and Synthesize CD3-ε Chain

Claudia G. Sáez, PhD, Valeria Matus, PhD, Olga Panes, Jaime Pereira, MD, Diego Mezzano, MD

Blood (2008) 112 (11): 5363.

https://doi.org/10.1182/blood.V112.11.5363.5363

Published: 2008

Journal Articles

Evidence of Endothelial Dysfunction in Cocaine Users.

Jai me Pereira, MD, Claudia G. Sáez, PhD, Julio Pallavicini, MD, Paulina Olivares, Olga Panes, Natalia Moreno, Sabine Belmont, Teresa Massardo, MD, Diego Mezzano, MD

Blood (2008) 112 (11): 1891.

https://doi.org/10.1182/blood.V112.11.1891.1891

Published: 2008

Journal Articles

Human platelets synthesize and express functional tissue factor

Olga Panes, Valeria Matus, Claudia G. Sáez, Teresa Quiroga, Jaime Pereira, Diego Mezzano

Blood (2007) 109 (12): 5242–5250.

https://doi.org/10.1182/blood-2006-06-030619

Published: 2007

Includes: Supplemental data

Journal Articles

Human Platelet Tissue Factor Is Localized in Lipid Rafts and Is Associated with GPIb-IX-V Complex in the Membrane: Association between Adhesive and Procoagulant Activities of Platelets.

Olga Panes, Valeria Matus, PhD, Claudia G. Sáez, PhD, Alan Gárate, Jaime Pereira, MD, Diego Mezzano, MD

Blood (2006) 108 (11): 1474.

https://doi.org/10.1182/blood.V108.11.1474.1474

Published: 2006

Journal Articles

Elevated Levels of Cell-Derived Microparticles with Procoagulant Activity in Cocaine Abusers: Association with Increased Thrombin Generation and a Prothrombotic State.

Jaime Pereira, MD, Gino Alfaro, Teresa Massardo, MD, Julio Pallavicini, MD, Claudia Sáez, PhD, Manuela Goycoolea, Olga Panes, Diego Mezzano, MD

Blood (2005) 106 (11): 2629.

https://doi.org/10.1182/blood.V106.11.2629.2629

Published: 2005

Journal Articles

Diagnostic Assessment of Patients with Inherited Mucocutaneous Hemorrhages (IMCH): Opening a Pandora Box?.

Diego Mezzano, MD, Teresa Quiroga, MD, Manuela Goycoolea, Blanca Muñoz, Eduardo Aranda, Olga Panes, Jaime Pereira, MD

Blood (2004) 104 (11): 4009.

https://doi.org/10.1182/blood.V104.11.4009.4009

Published: 2004

Journal Articles

Loss of Platelet Membrane Phospholipid Asymmetry in Systemic Lupus Erythematosus: Association with Disease Activity and Hypercoagulable State.

Jaime Pereira, MD, Teresa Quiroga, MD, Loreto Massardo, MD, Carol Pérez, MD, Gino Alfaro, Mauricio Ocqueteau, MD, Olga Panes, Diego Mezzano, MD

Blood (2004) 104 (11): 2588.

https://doi.org/10.1182/blood.V104.11.2588.2588

Published: 2004

NARROW

Gpibα Engagement Induces Activation of Human Platelet TF and Association with Constitutively Platelet Surface-Bound FVIIa

Platelet Tissue Factor Activity Is Specifically Induced By Gpib Activation Pathway, Independent of GPVI, α IIb β and Protein Disulfide Isomerase Activities

GPIbα Activation Triggers Platelet Tissue Factor/FVIIa-Dependent Procoagulant Activity, Which Is Dampened By Platelet Secreted TFPI and Protein S. Novel Platelet-Based Model of Hemostasis

Tissue Factor-Dependent Pro-Coagulant Activity Of Human Platelets Is Directly Related To Membrane Cholesterol Content. Rosuvastatin, But Not Atorvastatin, Reduces The Platelet Cholesterol, Tissue Factor Protein and Clotting Activity In Hypercholesterolemic Patients

Platelet Glycoprotein VI: An Adenine Insertion in Exon 6 Generates a Truncated Form of the Protein Associated with Bleeding Disorder in 4 Chilean Unrelated Patients

Circulating Human Platelets Express LRP-1 and uPAR mRNAs and Synthesize the Proteins: The Complex LRP-1, uPAR, PAI-1 and uPA Play a Role in Modulating Fibrinolysis in Platelet-Rich Thrombi

Platelet Tissue Factor Activity In Patients with Hypercholesterolemia: Modulation of Procoagulant Activity by Statins

Platelet Tissue Factor: Expression of Pro-Coagulant Activity depends on Gpibα Activation and Signaling through Lyn-Mediated Phosphorylation. A Platelet-Based Model of Hemostasis

Human Platelets Express and Synthesize CD3-ε Chain

Evidence of Endothelial Dysfunction in Cocaine Users.

Human platelets synthesize and express functional tissue factor

Human Platelet Tissue Factor Is Localized in Lipid Rafts and Is Associated with GPIb-IX-V Complex in the Membrane: Association between Adhesive and Procoagulant Activities of Platelets.

Elevated Levels of Cell-Derived Microparticles with Procoagulant Activity in Cocaine Abusers: Association with Increased Thrombin Generation and a Prothrombotic State.

Diagnostic Assessment of Patients with Inherited Mucocutaneous Hemorrhages (IMCH): Opening a Pandora Box?.

Loss of Platelet Membrane Phospholipid Asymmetry in Systemic Lupus Erythematosus: Association with Disease Activity and Hypercoagulable State.

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American Society of Hematology

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American Society of Hematology

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