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Journal Articles

Evidence of Endothelial Dysfunction and Activation of RhoA/Rho Kinase Pathway in Inflammatory Bowel Disease

Jaime Pereira, MD, Claudia G Saez, PhD, Manuel Alvarez, MD, Felipe Silva, MD, Nixa Olivares, Jose G Valenzuela, Antonia Pastore, Diego Mezzano, MD

Blood (2019) 134 (Supplement_1): 3641.

https://doi.org/10.1182/blood-2019-126033

Published: 2019

Journal Articles

Time to Change Our Practice: Experience in the Treatment of Steroid Refractory Graft Versus Host Disease in a Universitary Hospital in Chile

Nicolas Triantafilo, MD, Mauricio Sarmiento Maldonado, MD, Felipe Palacios, MD, James Campbell, MD, Vicente Sandoval, MD, Andres Rojas, MD, Jara Veronica, Soto Katherine, Silvana Arellano, Carla Lorca, Isabel Pizarro, Elizabeth Rivera, Mauricio Galleguillos, Isabel Rodriguez, Pablo Bertin, MD, Mauricio Ocqueteau, MD, Jaime Pereira, MD

Blood (2019) 134 (Supplement_1): 5683.

https://doi.org/10.1182/blood-2019-131737

Published: 2019

Journal Articles

Historical Analysis of a Cohort of Chilean Patients Treated with Autologous Stem Cell Transplantation Since 1993: Optimization of Stem Cell Collections, Risk Factors for Poor Mobilizers and Efficient Plerixafor Use

Mauricio Sarmiento Maldonado, MD, Jara Veronica, Silvana Arellano, Soto Katherine, Carla Lorca, Isabel Pizarro, Pablo Bertin, MD, Mauricio Galleguillos, Elizabeth Rivera, Isabel Rodriguez, Nicole Beffermann, Mauricio Ocqueteau, MD, Jaime Pereira, MD

Blood (2019) 134 (Supplement_1): 5641.

https://doi.org/10.1182/blood-2019-124328

Published: 2019

Journal Articles

Gpibα Engagement Induces Activation of Human Platelet TF and Association with Constitutively Platelet Surface-Bound FVIIa

Olga Panes, Biochemist, M. Francisca Becerra, Biochemist, Roger Valle, Biochemist, Claudia G Sáez, PhD, Patricia Hidalgo, MT, Jaime Pereira, MD, Jennifer Royce, Wolfram Ruf, MD, PhD, Diego Mezzano, MD

Blood (2019) 134 (Supplement_1): 2337.

https://doi.org/10.1182/blood-2019-126359

Published: 2019

Journal Articles

Endothelial Dysfunction and Platelet Activation in Major Depressive Disorder: Association with Brain Perfusion Abnormalities

Jaime Pereira, MD, Teresa Massardo, MD, Claudia G Saez, PhD, Nixa Olivares, Jose G Valenzuela, Luis Risco, MD, Jonathan Veliz, MD, Jane Spuler, MD, Gabriel Castro, MD, Ellieth Falloux, MD, Carolina Villa, MD, Juan C Quintana, MD, Daniel Vicentini, MD, Diego Mezzano, MD

Blood (2018) 132 (Supplement 1): 4968.

https://doi.org/10.1182/blood-2018-99-113565

Published: 2018

Journal Articles

Platelet Tissue Factor Activity Is Specifically Induced By Gpib Activation Pathway, Independent of GPVI, α IIb β and Protein Disulfide Isomerase Activities

Olga Panes, BM, BCh, Valeria Matus, PhD, Claudia G Sáez, PhD, Jaime Pereira, MD, Luz María Pozo, BCh, Diego Mezzano, MD

Blood (2017) 130 (Supplement 1): 2305.

https://doi.org/10.1182/blood.V130.Suppl_1.2305.2305

Published: 2017

Journal Articles

Interaction of Human Platelets with Enterohemorrhagic E. coli O111, Induces an Increase in the Procoagulant Activity, Thrombin Generation and Adhesion to Endothelial Cells

Valeria Matus, PhD, José Guillermo Valenzuela, Claudia G Sáez, PhD, Patricia Hidalgo, Karla Pereira, Jaime Pereira, MD, Diego Mezzano, MD

Blood (2014) 124 (21): 4989.

https://doi.org/10.1182/blood.V124.21.4989.4989

Published: 2014

Journal Articles

GPIbα Activation Triggers Platelet Tissue Factor/FVIIa-Dependent Procoagulant Activity, Which Is Dampened By Platelet Secreted TFPI and Protein S. Novel Platelet-Based Model of Hemostasis

Olga Panes, César González, Gustavo Soto, Jaime Pereira, MD, Valeria Matus, PhD, Claudia G. Sáez, PhD, Patricia Hidalgo, Diego Mezzano, MD

Blood (2014) 124 (21): 1430.

https://doi.org/10.1182/blood.V124.21.1430.1430

Published: 2014

Journal Articles

Role of Sigma-1 Receptor in Cocaine-Induced Endothelial Cell Damage

Jaime Pereira, MD, María P Hernández, Claudia G Saez, PhD, Karla Pereira-Flores, Alberto Leguina, Diego Mezzano, MD

Blood (2014) 124 (21): 1446.

https://doi.org/10.1182/blood.V124.21.1446.1446

Published: 2014

Journal Articles

Tissue Factor-Dependent Pro-Coagulant Activity Of Human Platelets Is Directly Related To Membrane Cholesterol Content. Rosuvastatin, But Not Atorvastatin, Reduces The Platelet Cholesterol, Tissue Factor Protein and Clotting Activity In Hypercholesterolemic Patients

Olga Panes, Juan P. Valderas, M.D., Mónica Acevedo, M.D., Susana Contreras, Jaime Pereira, M.D., Attilio Rigotti, M.D., PhD., Diego Mezzano, M.D.

Blood (2013) 122 (21): 34.

https://doi.org/10.1182/blood.V122.21.34.34

Published: 2013

Journal Articles

Circulating Human Platelets Express LRP-1 and uPAR mRNAs and Synthesize the Proteins: The Complex LRP-1, uPAR, PAI-1 and uPA Play a Role in Modulating Fibrinolysis in Platelet-Rich Thrombi

Olga Panes, Valeria Matus, PhD, César González, Claudia G Sáez, PhD, Jaime Pereira, M.D., Diego Mezzano, M.D.

Blood (2012) 120 (21): 1116.

https://doi.org/10.1182/blood.V120.21.1116.1116

Published: 2012

Journal Articles

Platelet Glycoprotein VI: An Adenine Insertion in Exon 6 Generates a Truncated Form of the Protein Associated with Bleeding Disorder in 4 Chilean Unrelated Patients

Valeria Matus, PhD, José Guillermo Valenzuela, Claudia G Sáez, PhD, Patricia Hidalgo, Olga Panes, Jaime Pereira, M.D., Diego Mezzano, M.D.

Blood (2012) 120 (21): 3302.

https://doi.org/10.1182/blood.V120.21.3302.3302

Published: 2012

Journal Articles

Cocaine-Induced Endothelial Dysfunction: Role of RhoA/Rho Kinase Pathway Activation.

Jaime Pereira, M.D., Claudia G Saez, Ph.D., Julio Pallavicini, M.D., Karla Pereira-Flores, Camila Mendoza, Romina Hernández, Ph.D., Ulises Novoa, María Paz Ocaranza, Ph.D., Teresa Massardo, M.D., Diego Mezzano, M.D., Jorge Jalil, M.D.

Blood (2012) 120 (21): 2177.

https://doi.org/10.1182/blood.V120.21.2177.2177

Published: 2012

Journal Articles

Human Platelets Express Functional Pannexin-1

Jaime Pereira, MD, Kenji F Shoji, Anibal A Vargas, Juan A Orellana, Claudia G Saez, Ph.D., Karla Pereira, Cathy Paddock, Christopher Kuckleburg, PhD, Peter J. Newman, PhD, Diego Mezzano, MD, Juan C Sáez, Ph.D.

Blood (2011) 118 (21): 1132.

https://doi.org/10.1182/blood.V118.21.1132.1132

Published: 2011

Journal Articles

Platelet Tissue Factor Activity In Patients with Hypercholesterolemia: Modulation of Procoagulant Activity by Statins

Olga Panes, Mónica Acevedo, M.D., Valeria Matus, PhD, Claudia G. Sáez, PhD, Jaime Pereira, MD, Diego Mezzano, MD

Blood (2010) 116 (21): 156.

https://doi.org/10.1182/blood.V116.21.156.156

Published: 2010

Journal Articles

Effect of Short-Term Abstinence on Cocaine-Induced Endothelial Dysfunction and Platelet Activation

Jaime Pereira, MD, Claudia G Saez, Ph.D., Julio Pallavicini, M.D., Paulina Olivares, PhD, Natalia Moreno, PhD, Manuel Cabreras, Teresa Massardo, M.D., Diego Mezzano, MD

Blood (2010) 116 (21): 4205.

https://doi.org/10.1182/blood.V116.21.4205.4205

Published: 2010

Journal Articles

Platelet Tissue Factor: Fast and Specific Clotting Activation Pathway Mediated by VWF-GPIba Interaction and Platelet Membrane FVII. Human Platelets Contain All the Components for Assembling the Prothrombinase Complex and Their Procoagulant Function Is Independent of Aggregation/Secretion and GPVI Function.

Olga Panes, Valeria Matus, PhD, Claudia G. Sáaez, PhD, Jaime Pereira, MD, Diego Mezzano, MD

Blood (2009) 114 (22): 3000.

https://doi.org/10.1182/blood.V114.22.3000.3000

Published: 2009

Journal Articles

Platelet Tissue Factor: Expression of Pro-Coagulant Activity depends on Gpibα Activation and Signaling through Lyn-Mediated Phosphorylation. A Platelet-Based Model of Hemostasis

Olga Panes, Paula Ibarra, Valeria Matus, PhD, Claudia G. Sáez, PhD, Jaime Pereira, MD, Diego Mezzano, MD

Blood (2008) 112 (11): 113.

https://doi.org/10.1182/blood.V112.11.113.113

Published: 2008

Journal Articles

Human Platelets Express and Synthesize CD3-ε Chain

Claudia G. Sáez, PhD, Valeria Matus, PhD, Olga Panes, Jaime Pereira, MD, Diego Mezzano, MD

Blood (2008) 112 (11): 5363.

https://doi.org/10.1182/blood.V112.11.5363.5363

Published: 2008

Journal Articles

Human platelets synthesize and express functional tissue factor

Olga Panes, Valeria Matus, Claudia G. Sáez, Teresa Quiroga, Jaime Pereira, Diego Mezzano

Blood (2007) 109 (12): 5242–5250.

https://doi.org/10.1182/blood-2006-06-030619

Published: 2007

Includes: Supplemental data

NARROW

Evidence of Endothelial Dysfunction and Activation of RhoA/Rho Kinase Pathway in Inflammatory Bowel Disease

Time to Change Our Practice: Experience in the Treatment of Steroid Refractory Graft Versus Host Disease in a Universitary Hospital in Chile

Historical Analysis of a Cohort of Chilean Patients Treated with Autologous Stem Cell Transplantation Since 1993: Optimization of Stem Cell Collections, Risk Factors for Poor Mobilizers and Efficient Plerixafor Use

Gpibα Engagement Induces Activation of Human Platelet TF and Association with Constitutively Platelet Surface-Bound FVIIa

Endothelial Dysfunction and Platelet Activation in Major Depressive Disorder: Association with Brain Perfusion Abnormalities

Platelet Tissue Factor Activity Is Specifically Induced By Gpib Activation Pathway, Independent of GPVI, α IIb β and Protein Disulfide Isomerase Activities

Interaction of Human Platelets with Enterohemorrhagic E. coli O111, Induces an Increase in the Procoagulant Activity, Thrombin Generation and Adhesion to Endothelial Cells

GPIbα Activation Triggers Platelet Tissue Factor/FVIIa-Dependent Procoagulant Activity, Which Is Dampened By Platelet Secreted TFPI and Protein S. Novel Platelet-Based Model of Hemostasis

Role of Sigma-1 Receptor in Cocaine-Induced Endothelial Cell Damage

Tissue Factor-Dependent Pro-Coagulant Activity Of Human Platelets Is Directly Related To Membrane Cholesterol Content. Rosuvastatin, But Not Atorvastatin, Reduces The Platelet Cholesterol, Tissue Factor Protein and Clotting Activity In Hypercholesterolemic Patients

Circulating Human Platelets Express LRP-1 and uPAR mRNAs and Synthesize the Proteins: The Complex LRP-1, uPAR, PAI-1 and uPA Play a Role in Modulating Fibrinolysis in Platelet-Rich Thrombi

Platelet Glycoprotein VI: An Adenine Insertion in Exon 6 Generates a Truncated Form of the Protein Associated with Bleeding Disorder in 4 Chilean Unrelated Patients

Cocaine-Induced Endothelial Dysfunction: Role of RhoA/Rho Kinase Pathway Activation.

Human Platelets Express Functional Pannexin-1

Platelet Tissue Factor Activity In Patients with Hypercholesterolemia: Modulation of Procoagulant Activity by Statins

Effect of Short-Term Abstinence on Cocaine-Induced Endothelial Dysfunction and Platelet Activation

Platelet Tissue Factor: Expression of Pro-Coagulant Activity depends on Gpibα Activation and Signaling through Lyn-Mediated Phosphorylation. A Platelet-Based Model of Hemostasis

Human Platelets Express and Synthesize CD3-ε Chain

Human platelets synthesize and express functional tissue factor

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